STRINGSTRING
dnaX dnaX IQ63_02810 IQ63_02810 recG recG dnaE dnaE polA_1 polA_1 yceC_4 yceC_4 yceD_7 yceD_7 IQ63_08010 IQ63_08010 IQ63_08040 IQ63_08040 polA_3 polA_3 yceD_2 yceD_2 yceD_3 yceD_3 IQ63_11640 IQ63_11640 bmrR bmrR birA_2 birA_2 IQ63_12990 IQ63_12990 ssb1 ssb1 recD2_2 recD2_2 IQ63_15065 IQ63_15065 yceD_5 yceD_5 yceC_2 yceC_2 yceD_1 yceD_1 recR recR IQ63_17715 IQ63_17715 IQ63_17825 IQ63_17825 iucC_1 iucC_1 polC_2 polC_2 IQ63_22145 IQ63_22145 IQ63_22450 IQ63_22450 recA recA IQ63_23365 IQ63_23365 recF recF dnaN_2 dnaN_2 ssb2 ssb2 IQ63_26080 IQ63_26080 IQ63_26335 IQ63_26335 IQ63_26735 IQ63_26735 yceD_10 yceD_10 yceD_9-2 yceD_9-2 recO recO IQ63_31285 IQ63_31285 IQ63_34880 IQ63_34880 IQ63_35135 IQ63_35135 IQ63_35140 IQ63_35140 polA_2 polA_2 IQ63_35750 IQ63_35750 ruvC ruvC ruvA ruvA ruvB ruvB priA_1 priA_1 yceC_3 yceC_3 yceC_1 yceC_1 polC_1 polC_1 IQ63_43385 IQ63_43385 IQ63_44045 IQ63_44045 dnaN_1 dnaN_1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaXDNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
IQ63_02810DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (328 aa)
recGATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1072 aa)
dnaEDNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1179 aa)
polA_1DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (908 aa)
yceC_4Tellurium resistance protein terZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
yceD_7Export associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (637 aa)
IQ63_08010Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
IQ63_08040Mobilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa)
polA_33'-5' exonuclease; Similar to DNA polymerase I; lacks 5'-3' exonuclease domain; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)
yceD_2Stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
yceD_3Chemical-damaging agent resistance protein C; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
IQ63_11640DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (882 aa)
bmrRMerR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
birA_2Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
IQ63_12990AbrB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
ssb1Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
recD2_2Helicase; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. (750 aa)
IQ63_15065Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
yceD_5Chemical-damaging agent resistance protein C; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
yceC_2Tellurium resistance protein terZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
yceD_1Chemical-damaging agent resistance protein C; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
recRRecombinase RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (199 aa)
IQ63_17715Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
IQ63_17825Cell filamentation protein Fic; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
iucC_1Iron transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (496 aa)
polC_23'-5' exonuclease of DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
IQ63_22145DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
IQ63_22450TerD-family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
recARecombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (378 aa)
IQ63_23365Stress protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
recFRecombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (373 aa)
dnaN_2DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (376 aa)
ssb2Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
IQ63_26080Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
IQ63_26335DNA polymerase III subunit gamma/tau; Derived by automated computational analysis using gene prediction method: Protein Homology. (743 aa)
IQ63_26735Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
yceD_10Chemical-damaging agent resistance protein C; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
yceD_9-2Chemical-damaging agent resistance protein C; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)
recODNA recombination protein RecO; Involved in DNA repair and RecF pathway recombination. (249 aa)
IQ63_31285Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
IQ63_34880Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (885 aa)
IQ63_35135Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
IQ63_35140Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
polA_25'-3' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
IQ63_35750DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
ruvCHolliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (176 aa)
ruvAATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (201 aa)
ruvBATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (352 aa)
priA_1Primosome assembly protein PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (713 aa)
yceC_3Tellurium resistance protein terZ; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa)
yceC_1Stress-induced protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (398 aa)
polC_1DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
IQ63_43385Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (862 aa)
IQ63_44045TerD-family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (175 aa)
dnaN_1DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.