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SAE2 SAE2 A0A251S005 A0A251S005 A0A251S6U4 A0A251S6U4 A0A251S6V0 A0A251S6V0 A0A251SIJ3 A0A251SIJ3 TOP2 TOP2 A0A251SS39 A0A251SS39 SUMO1 SUMO1 A0A251T4V9 A0A251T4V9 ATSIZ1 ATSIZ1 A0A251TX27 A0A251TX27 ATSAE1B ATSAE1B A0A251UPC5 A0A251UPC5 SUM2 SUM2 A0A251VIU5 A0A251VIU5 A0A251VJJ7 A0A251VJJ7 MGO1 MGO1 TOPII TOPII A0A251VPJ6 A0A251VPJ6
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
SAE2SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. (647 aa)
A0A251S005DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (847 aa)
A0A251S6U4Small ubiquitin-related modifier. (94 aa)
A0A251S6V0Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
A0A251SIJ3Small ubiquitin-related modifier. (102 aa)
TOP2DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1488 aa)
A0A251SS39Putative zinc finger, PHD-type. (783 aa)
SUMO1Small ubiquitin-related modifier. (104 aa)
A0A251T4V9Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
ATSIZ1Putative DNA-binding protein. (885 aa)
A0A251TX27Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
ATSAE1BPutative SUMO activating enzyme 1B. (319 aa)
A0A251UPC5Putative rad60/SUMO-like domain, Ubiquitin-related domain protein. (90 aa)
SUM2Small ubiquitin-related modifier. (104 aa)
A0A251VIU5Putative zinc finger, PHD-type. (846 aa)
A0A251VJJ7Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. (160 aa)
MGO1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (776 aa)
TOPIIDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1499 aa)
A0A251VPJ6Putative SAP domain-containing protein. (862 aa)
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
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