(23 nodes) Mixed, incl. CENP-T/Histone H4, histone fold, and Histone H3 network (Helianthus annuus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A251RR84	Putative SNF2-related, N-terminal domain-containing protein. (2681 aa)
	A0A251S7R1	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (107 aa)
	A0A251S9Y5	Histone H3; Belongs to the histone H3 family. (136 aa)
	H33	Putative histone H3.3. (143 aa)
	A0A251SAQ0	Putative histone H3/CENP-A. (213 aa)
	A0A251SEX0	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (127 aa)
	H33-2	Putative histone H3.3. (146 aa)
	H2A	Histone H2A; Belongs to the histone H2A family. (150 aa)
	TPR10	Putative ankyrin repeat family protein. (488 aa)
	A0A251SP40	Uncharacterized protein. (115 aa)
	A0A251T1X4	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	A0A251T2S4	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (192 aa)
	H2AV2	Histone H2A; Belongs to the histone H2A family. (139 aa)
	H2B	Histone H2B; Belongs to the histone H2B family. (137 aa)
	A0A251U3T0	Putative histone H2B; Belongs to the histone H2B family. (66 aa)
	SDG26	Putative SET domain group 26. (460 aa)
	A0A251U783	Histone H2B; Belongs to the histone H2B family. (141 aa)
	A0A251UL39	Histone H2A; Belongs to the histone H2A family. (225 aa)
	A0A251UP18	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (121 aa)
	A0A251UR62	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (203 aa)
	H32	Putative histone H3 type 2. (133 aa)
	H3-2	Histone H3; Belongs to the histone H3 family. (133 aa)
	ASHH2	Putative histone-lysine N-methyltransferase ASHH2. (1420 aa)

Your Current Organism:

Helianthus annuus

NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251RR84	A0A251S7R1	A0A251RR84	A0A251S7R1	Putative SNF2-related, N-terminal domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.894
A0A251RR84	A0A251S9Y5	A0A251RR84	A0A251S9Y5	Putative SNF2-related, N-terminal domain-containing protein.	Histone H3; Belongs to the histone H3 family.	0.880
A0A251RR84	A0A251SAQ0	A0A251RR84	A0A251SAQ0	Putative SNF2-related, N-terminal domain-containing protein.	Putative histone H3/CENP-A.	0.880
A0A251RR84	A0A251SEX0	A0A251RR84	A0A251SEX0	Putative SNF2-related, N-terminal domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.894
A0A251RR84	A0A251SP40	A0A251RR84	A0A251SP40	Putative SNF2-related, N-terminal domain-containing protein.	Uncharacterized protein.	0.919
A0A251RR84	A0A251T1X4	A0A251RR84	A0A251T1X4	Putative SNF2-related, N-terminal domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.894
A0A251RR84	A0A251T2S4	A0A251RR84	A0A251T2S4	Putative SNF2-related, N-terminal domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.894
A0A251RR84	A0A251U3T0	A0A251RR84	A0A251U3T0	Putative SNF2-related, N-terminal domain-containing protein.	Putative histone H2B; Belongs to the histone H2B family.	0.764
A0A251RR84	A0A251U783	A0A251RR84	A0A251U783	Putative SNF2-related, N-terminal domain-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.764
A0A251RR84	A0A251UL39	A0A251RR84	A0A251UL39	Putative SNF2-related, N-terminal domain-containing protein.	Histone H2A; Belongs to the histone H2A family.	0.407
A0A251RR84	A0A251UP18	A0A251RR84	A0A251UP18	Putative SNF2-related, N-terminal domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.894
A0A251RR84	A0A251UR62	A0A251RR84	A0A251UR62	Putative SNF2-related, N-terminal domain-containing protein.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.894
A0A251RR84	H2A	A0A251RR84	A0A251SL05	Putative SNF2-related, N-terminal domain-containing protein.	Histone H2A; Belongs to the histone H2A family.	0.662
A0A251RR84	H2AV2	A0A251RR84	A0A251TRT7	Putative SNF2-related, N-terminal domain-containing protein.	Histone H2A; Belongs to the histone H2A family.	0.407
A0A251RR84	H2B	A0A251RR84	A0A251U3R7	Putative SNF2-related, N-terminal domain-containing protein.	Histone H2B; Belongs to the histone H2B family.	0.764
A0A251RR84	H3-2	A0A251RR84	A0A251URE9	Putative SNF2-related, N-terminal domain-containing protein.	Histone H3; Belongs to the histone H3 family.	0.880
A0A251RR84	H32	A0A251RR84	A0A251UR94	Putative SNF2-related, N-terminal domain-containing protein.	Putative histone H3 type 2.	0.880
A0A251RR84	H33	A0A251RR84	A0A251SAB5	Putative SNF2-related, N-terminal domain-containing protein.	Putative histone H3.3.	0.880
A0A251RR84	H33-2	A0A251RR84	A0A251SJA9	Putative SNF2-related, N-terminal domain-containing protein.	Putative histone H3.3.	0.880
A0A251RR84	TPR10	A0A251RR84	A0A251SM03	Putative SNF2-related, N-terminal domain-containing protein.	Putative ankyrin repeat family protein.	0.955