STRINGSTRING
ORC4 ORC4 A0A251RM95 A0A251RM95 A0A251RPQ8 A0A251RPQ8 A0A251RQ30 A0A251RQ30 A0A251RQ80 A0A251RQ80 A0A251RQY4 A0A251RQY4 CDC6 CDC6 A0A251RUX6 A0A251RUX6 A0A251RXW4 A0A251RXW4 RS27A RS27A A0A251S1T2 A0A251S1T2 A0A251S4H2 A0A251S4H2 ATCDT1B ATCDT1B A0A251S7X4 A0A251S7X4 CDC27 CDC27 A0A251S9C9 A0A251S9C9 A0A251SBH9 A0A251SBH9 ORC3 ORC3 A0A251SBX3 A0A251SBX3 A0A251SCQ6 A0A251SCQ6 A0A251SDE3 A0A251SDE3 A0A251SF10 A0A251SF10 A0A251SF17 A0A251SF17 A0A251SFZ0 A0A251SFZ0 APC8 APC8 A0A251SJG0 A0A251SJG0 A0A251SME6 A0A251SME6 A0A251SMV7 A0A251SMV7 A0A251SNJ0 A0A251SNJ0 MCM4 MCM4 MCM8 MCM8 UBE2C UBE2C A0A251SSV1 A0A251SSV1 A0A251ST95 A0A251ST95 APC7 APC7 A0A251STP7 A0A251STP7 A0A251SVJ2 A0A251SVJ2 PBF1 PBF1 APC2 APC2 ORC6 ORC6 A0A251T273 A0A251T273 A0A251T2C4 A0A251T2C4 A0A251T4N6 A0A251T4N6 A0A251T6K2 A0A251T6K2 A0A251T846 A0A251T846 APC6 APC6 PBB2 PBB2 A0A251T9Z0 A0A251T9Z0 H2B3 H2B3 PDE149 PDE149 ATCDT1A ATCDT1A A0A251TGA6 A0A251TGA6 H2B1 H2B1 A0A251TLB9 A0A251TLB9 MCM7 MCM7 MCM7-2 MCM7-2 A0A251TSA8 A0A251TSA8 A0A251TTB4 A0A251TTB4 A0A251TUX0 A0A251TUX0 A0A251TZE4 A0A251TZE4 A0A251U0T2 A0A251U0T2 A0A251U1U8 A0A251U1U8 A0A251U2C8 A0A251U2C8 H2B H2B A0A251U3T0 A0A251U3T0 HTB1 HTB1 IMB1 IMB1 A0A251U6A5 A0A251U6A5 A0A251U6B0 A0A251U6B0 A0A251U6D9 A0A251U6D9 A0A251U736 A0A251U736 A0A251U783 A0A251U783 A0A251U8C5 A0A251U8C5 A0A251UA37 A0A251UA37 MCM6 MCM6 ORC1B ORC1B A0A251UC72 A0A251UC72 UBC22 UBC22 MCM7-3 MCM7-3 H2B1-2 H2B1-2 A0A251UIE9 A0A251UIE9 A0A251UJ05 A0A251UJ05 MCM2 MCM2 A0A251UJE0 A0A251UJE0 A0A251UJW3 A0A251UJW3 UBC20 UBC20 A0A251ULH4 A0A251ULH4 MCM5 MCM5 A0A251US39 A0A251US39 A0A251USC4 A0A251USC4 A0A251UUP3 A0A251UUP3 A0A251UVG2 A0A251UVG2 ORC2 ORC2 A0A251UX10 A0A251UX10 A0A251UYH8 A0A251UYH8 A0A251UYL0 A0A251UYL0 HBT HBT A0A251UZY1 A0A251UZY1 ORC5 ORC5 MCM31 MCM31 A0A251V2W8 A0A251V2W8 MCM4-2 MCM4-2 MCM9 MCM9 PSB6 PSB6 A0A251V7Y5 A0A251V7Y5 PBA1 PBA1 PSB1 PSB1 A0A251VDK2 A0A251VDK2 A0A251VFH3 A0A251VFH3 A0A251VGJ2 A0A251VGJ2 A0A251VPL1 A0A251VPL1 A0A251VQX3 A0A251VQX3
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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ORC4Origin of replication complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (424 aa)
A0A251RM95Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (251 aa)
A0A251RPQ8Putative winged helix-turn-helix DNA-binding domain-containing protein. (171 aa)
A0A251RQ30Putative transducin/WD40 repeat-like superfamily protein. (753 aa)
A0A251RQ80Putative armadillo-type fold, Importin subunit beta-1, plant. (386 aa)
A0A251RQY4Putative armadillo-type fold, Importin subunit beta-1, plant. (623 aa)
CDC6Cell division control protein; Belongs to the CDC6/cdc18 family. (561 aa)
A0A251RUX6Putative armadillo-type fold, Importin subunit beta-1, plant. (218 aa)
A0A251RXW4Putative P-loop containing nucleoside triphosphate hydrolase. (76 aa)
RS27APutative ubiquitin-40S ribosomal protein S27a. (153 aa)
A0A251S1T2Putative BYPASS related protein. (324 aa)
A0A251S4H2Uncharacterized protein. (56 aa)
ATCDT1BPutative CDT1-B-like protein. (517 aa)
A0A251S7X4Putative ribosomal protein L9/RNase H1, Ribonuclease H1. (286 aa)
CDC27Putative cell division cycle protein. (760 aa)
A0A251S9C9Putative 43kDa postsynaptic protein. (215 aa)
A0A251SBH9Histone H2B; Belongs to the histone H2B family. (134 aa)
ORC3Putative origin recognition complex subunit 3. (708 aa)
A0A251SBX3Histone H2B; Belongs to the histone H2B family. (141 aa)
A0A251SCQ6Putative acetyltransferase A, auxiliary subunit. (538 aa)
A0A251SDE3Putative ARM repeat superfamily protein. (526 aa)
A0A251SF10Putative GLTSCR protein, conserved region. (326 aa)
A0A251SF17Putative winged helix-turn-helix DNA-binding domain-containing protein. (110 aa)
A0A251SFZ0Histone H2B; Belongs to the histone H2B family. (142 aa)
APC8Putative anaphase-promoting complex subunit 8. (572 aa)
A0A251SJG0Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. (271 aa)
A0A251SME6Putative E3 ubiquitin ligase, putative. (1820 aa)
A0A251SMV7Putative nucleic acid-binding, OB-fold protein. (61 aa)
A0A251SNJ0Histone H2B; Belongs to the histone H2B family. (173 aa)
MCM4DNA helicase; Belongs to the MCM family. (721 aa)
MCM8Putative DNA helicase MCM8; Belongs to the MCM family. (786 aa)
UBE2CPutative ubiquitin-conjugating enzyme E2 C; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)
A0A251SSV1Putative histone H2B; Belongs to the histone H2B family. (230 aa)
A0A251ST95Putative P-loop containing nucleoside triphosphate hydrolase. (106 aa)
APC7Putative tetratricopeptide repeat (TPR)-containing protein. (560 aa)
A0A251STP7Histone H2B; Belongs to the histone H2B family. (136 aa)
A0A251SVJ2Putative origin recognition complex, subunit 6, metazoa/plant. (102 aa)
PBF1Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (223 aa)
APC2Putative anaphase-promoting complex/cyclosome 2; Belongs to the cullin family. (869 aa)
ORC6Putative origin recognition complex protein 6. (285 aa)
A0A251T273Putative ribonuclease H, bacteria. (311 aa)
A0A251T2C4Putative zinc-binding ribosomal protein, Ubiquitin, Ubiquitin-related domain protein. (153 aa)
A0A251T4N6Putative ubiquitin-conjugating enzyme/RWD-like protein. (116 aa)
A0A251T6K2Putative ribosomal protein L9/RNase H1. (277 aa)
A0A251T846Putative RNase H family protein. (286 aa)
APC6Putative anaphase promoting complex 6. (537 aa)
PBB2Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (269 aa)
A0A251T9Z0GLTSCR1 domain-containing protein. (351 aa)
H2B3Histone H2B; Belongs to the histone H2B family. (142 aa)
PDE149Putative integral membrane TerC family protein. (361 aa)
ATCDT1APutative CDT1-A-like protein. (517 aa)
A0A251TGA6Putative MCM domain-containing protein. (142 aa)
H2B1Histone H2B; Belongs to the histone H2B family. (139 aa)
A0A251TLB9Putative armadillo-type fold protein. (120 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (146 aa)
MCM7-2DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (171 aa)
A0A251TSA8Putative winged helix-turn-helix DNA-binding domain, CDT1 Geminin-binding domain-like protein. (458 aa)
A0A251TTB4Histone H2B; Belongs to the histone H2B family. (166 aa)
A0A251TUX0Histone H2B; Belongs to the histone H2B family. (66 aa)
A0A251TZE4Putative polynucleotidyl transferase, ribonuclease H-like superfamily protein. (271 aa)
A0A251U0T2Putative armadillo-type fold, Importin subunit beta-1, plant. (123 aa)
A0A251U1U8Putative winged helix-turn-helix DNA-binding domain-containing protein. (105 aa)
A0A251U2C8Putative origin recognition complex, subunit 6. (285 aa)
H2BHistone H2B; Belongs to the histone H2B family. (137 aa)
A0A251U3T0Putative histone H2B; Belongs to the histone H2B family. (66 aa)
HTB1Histone H2B; Belongs to the histone H2B family. (139 aa)
IMB1Putative importin subunit beta-1. (869 aa)
A0A251U6A5Histone H2B; Belongs to the histone H2B family. (272 aa)
A0A251U6B0Putative histone H2B; Belongs to the histone H2B family. (128 aa)
A0A251U6D9Putative histone H2B. (107 aa)
A0A251U736Histone H2B; Belongs to the histone H2B family. (133 aa)
A0A251U783Histone H2B; Belongs to the histone H2B family. (141 aa)
A0A251U8C5Cell division control protein; Belongs to the CDC6/cdc18 family. (527 aa)
A0A251UA37Putative histone H2B; Belongs to the histone H2B family. (119 aa)
MCM6DNA helicase; Belongs to the MCM family. (839 aa)
ORC1BOrigin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (827 aa)
A0A251UC72Histone H2B; Belongs to the histone H2B family. (175 aa)
UBC22Putative ubiquitin-conjugating enzyme 22; Belongs to the ubiquitin-conjugating enzyme family. (271 aa)
MCM7-3DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (717 aa)
H2B1-2Histone H2B; Belongs to the histone H2B family. (148 aa)
A0A251UIE9Putative proteasome, subunit alpha/beta, nucleophile aminohydrolase. (119 aa)
A0A251UJ05Putative armadillo-type fold, Importin subunit beta-1, plant. (953 aa)
MCM2DNA helicase; Belongs to the MCM family. (958 aa)
A0A251UJE0Putative ubiquitin-conjugating enzyme/RWD-like protein; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
A0A251UJW3Putative ARM repeat superfamily protein. (953 aa)
UBC20Putative ubiquitin-conjugating enzyme 20; Belongs to the ubiquitin-conjugating enzyme family. (172 aa)
A0A251ULH4Histone H2B; Belongs to the histone H2B family. (120 aa)
MCM5DNA helicase; Belongs to the MCM family. (730 aa)
A0A251US39Putative 43kDa postsynaptic protein, Cdc23. (571 aa)
A0A251USC4Putative GLTSCR protein, conserved region. (227 aa)
A0A251UUP3Putative armadillo-type fold, Importin subunit beta-1, plant. (588 aa)
A0A251UVG2Putative importin subunit beta-1, plant. (83 aa)
ORC2Putative origin of replication complex subunit 2. (363 aa)
A0A251UX10Putative histone H2B; Belongs to the histone H2B family. (134 aa)
A0A251UYH8Putative histone H2B; Belongs to the histone H2B family. (85 aa)
A0A251UYL0Putative ARM repeat superfamily protein. (872 aa)
HBTPutative CDC27 family protein. (763 aa)
A0A251UZY1Histone H2B; Belongs to the histone H2B family. (138 aa)
ORC5Putative origin recognition complex protein 5. (538 aa)
MCM31DNA helicase. (757 aa)
A0A251V2W8Putative proteasome inhibitor-related protein. (302 aa)
MCM4-2DNA helicase; Belongs to the MCM family. (806 aa)
MCM9DNA helicase. (666 aa)
PSB6Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (234 aa)
A0A251V7Y5Putative DNA replication licensing factor Mcm2. (61 aa)
PBA1Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (237 aa)
PSB1Proteasome subunit beta; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH; Belongs to the peptidase T1B family. (223 aa)
A0A251VDK2Putative histone H2B; Belongs to the histone H2B family. (138 aa)
A0A251VFH3Putative armadillo-type fold, Importin subunit beta-1, plant. (161 aa)
A0A251VGJ2Uncharacterized protein. (93 aa)
A0A251VPL1Histone H2B; Belongs to the histone H2B family. (144 aa)
A0A251VQX3Histone H2B; Belongs to the histone H2B family. (144 aa)
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
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