(30 nodes) (2019) Phytomedicines Used for Diabetes Mellitus in Ghana: A Systematic Search and Review of Preclinical and Clinical Evidence. network (Helianthus annuus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

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Your Input:
	ATHXK2	Phosphotransferase. (498 aa)
	PHSL2	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (916 aa)
	HKL1	Phosphotransferase. (507 aa)
	HKL3	Phosphotransferase. (552 aa)
	ACX4	Putative acyl-CoA oxidase 4. (440 aa)
	A0A251THX1	Putative NAD(P)-linked oxidoreductase superfamily protein. (322 aa)
	A0A251TNQ2	Phosphotransferase. (496 aa)
	A0A251TRU4	Phosphotransferase. (498 aa)
	A0A251TUX7	3-hydroxy-3-methylglutaryl coenzyme A reductase. (572 aa)
	A0A251U3C3	3-hydroxy-3-methylglutaryl coenzyme A reductase. (590 aa)
	A0A251U744	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (643 aa)
	A0A251UFX0	Putative groES-like zinc-binding alcohol dehydrogenase family protein. (360 aa)
	HXK2	Phosphotransferase. (493 aa)
	PHSH	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (844 aa)
	ACX2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (696 aa)
	HXK2-2	Phosphotransferase. (492 aa)
	A0A251V019	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (985 aa)
	ATHXK4	Phosphotransferase. (509 aa)
	A0A251VHQ8	Putative glycosyl hydrolases family 31 protein; Belongs to the glycosyl hydrolase 31 family. (884 aa)
	A0A251VHZ1	Putative glycoside hydrolase family 31; Belongs to the glycosyl hydrolase 31 family. (885 aa)
	HXK1	Phosphotransferase. (494 aa)
	HMDH2-2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (597 aa)
	HMDH1	3-hydroxy-3-methylglutaryl coenzyme A reductase. (595 aa)
	ACX1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (663 aa)
	ACX3	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (672 aa)
	A0A251RTR2	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (657 aa)
	A0A251RT28	Phosphotransferase. (98 aa)
	HMDH	3-hydroxy-3-methylglutaryl coenzyme A reductase. (517 aa)
	HMDH2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (559 aa)
	PHSL1	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (955 aa)

Your Current Organism:

Helianthus annuus

NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251RT28	A0A251TNQ2	A0A251RT28	A0A251TNQ2	Phosphotransferase.	Phosphotransferase.	0.607
A0A251RT28	A0A251TRU4	A0A251RT28	A0A251TRU4	Phosphotransferase.	Phosphotransferase.	0.611
A0A251RT28	A0A251UFX0	A0A251RT28	A0A251UFX0	Phosphotransferase.	Putative groES-like zinc-binding alcohol dehydrogenase family protein.	0.738
A0A251RT28	A0A251V019	A0A251RT28	A0A251V019	Phosphotransferase.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.652
A0A251RT28	A0A251VHQ8	A0A251RT28	A0A251VHQ8	Phosphotransferase.	Putative glycosyl hydrolases family 31 protein; Belongs to the glycosyl hydrolase 31 family.	0.753
A0A251RT28	A0A251VHZ1	A0A251RT28	A0A251VHZ1	Phosphotransferase.	Putative glycoside hydrolase family 31; Belongs to the glycosyl hydrolase 31 family.	0.753
A0A251RT28	ATHXK2	A0A251RT28	A0A251SYJ3	Phosphotransferase.	Phosphotransferase.	0.610
A0A251RT28	ATHXK4	A0A251RT28	A0A251VHM7	Phosphotransferase.	Phosphotransferase.	0.632
A0A251RT28	HKL1	A0A251RT28	A0A251SV07	Phosphotransferase.	Phosphotransferase.	0.636
A0A251RT28	HKL3	A0A251RT28	A0A251T4K8	Phosphotransferase.	Phosphotransferase.	0.615
A0A251RT28	HXK1	A0A251RT28	A0A251SGS4	Phosphotransferase.	Phosphotransferase.	0.609
A0A251RT28	HXK2	A0A251RT28	A0A251UL92	Phosphotransferase.	Phosphotransferase.	0.616
A0A251RT28	HXK2-2	A0A251RT28	A0A251UUM1	Phosphotransferase.	Phosphotransferase.	0.609
A0A251RT28	PHSH	A0A251RT28	A0A251UMQ2	Phosphotransferase.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.624
A0A251RT28	PHSL1	A0A251RT28	A0A251RNZ4	Phosphotransferase.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.624
A0A251RT28	PHSL2	A0A251RT28	A0A251T1W8	Phosphotransferase.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.624
A0A251RTR2	A0A251U744	A0A251RTR2	A0A251U744	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.967
A0A251RTR2	A0A251VHQ8	A0A251RTR2	A0A251VHQ8	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Putative glycosyl hydrolases family 31 protein; Belongs to the glycosyl hydrolase 31 family.	0.416
A0A251RTR2	A0A251VHZ1	A0A251RTR2	A0A251VHZ1	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Putative glycoside hydrolase family 31; Belongs to the glycosyl hydrolase 31 family.	0.416
A0A251RTR2	ACX1	A0A251RTR2	A0A251RWE9	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.968