(15 nodes) (2020) Improved cis-Abienol production through increasing precursor supply in Escherichia coli. network (Helianthus annuus)

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Your Input:
	HMDH2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (559 aa)
	HMDH	3-hydroxy-3-methylglutaryl coenzyme A reductase. (517 aa)
	HMDH1	3-hydroxy-3-methylglutaryl coenzyme A reductase. (595 aa)
	HMDH2-2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (597 aa)
	ISPE	Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic. (400 aa)
	ISPG	Putative 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (Ferredoxin) protein. (740 aa)
	A0A251TUX7	3-hydroxy-3-methylglutaryl coenzyme A reductase. (572 aa)
	TPS4	Putative (E)-beta-ocimene synthase protein. (592 aa)
	A0A251U3C3	3-hydroxy-3-methylglutaryl coenzyme A reductase. (590 aa)
	FPPS	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family. (382 aa)
	HMCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (458 aa)
	GPPS	Putative geranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. (412 aa)
	ISPF	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. (232 aa)
	MVA1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (455 aa)
	PAC	Putative pale cress protein (PAC). (320 aa)

Your Current Organism:

Helianthus annuus

NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251TUX7	FPPS	A0A251TUX7	A0A251U7H3	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.718
A0A251TUX7	GPPS	A0A251TUX7	A0A251V4B7	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative geranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.695
A0A251TUX7	HMCS1	A0A251TUX7	A0A251UFJ6	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.974
A0A251TUX7	ISPE	A0A251TUX7	A0A251SIN7	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic.	0.680
A0A251TUX7	ISPF	A0A251TUX7	A0A251V9T9	3-hydroxy-3-methylglutaryl coenzyme A reductase.	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.	0.605
A0A251TUX7	ISPG	A0A251TUX7	A0A251SJU5	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (Ferredoxin) protein.	0.459
A0A251TUX7	MVA1	A0A251TUX7	A0A251VID0	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.997
A0A251U3C3	FPPS	A0A251U3C3	A0A251U7H3	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	0.723
A0A251U3C3	GPPS	A0A251U3C3	A0A251V4B7	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative geranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.696
A0A251U3C3	HMCS1	A0A251U3C3	A0A251UFJ6	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.974
A0A251U3C3	ISPE	A0A251U3C3	A0A251SIN7	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase, chloroplastic/chromoplastic.	0.680
A0A251U3C3	ISPF	A0A251U3C3	A0A251V9T9	3-hydroxy-3-methylglutaryl coenzyme A reductase.	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.	0.606
A0A251U3C3	ISPG	A0A251U3C3	A0A251SJU5	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (Ferredoxin) protein.	0.461
A0A251U3C3	MVA1	A0A251U3C3	A0A251VID0	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.997
FPPS	A0A251TUX7	A0A251U7H3	A0A251TUX7	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.718
FPPS	A0A251U3C3	A0A251U7H3	A0A251U3C3	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.723
FPPS	GPPS	A0A251U7H3	A0A251V4B7	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	Putative geranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family.	0.947
FPPS	HMCS1	A0A251U7H3	A0A251UFJ6	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.672
FPPS	HMDH	A0A251U7H3	A0A251RS13	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.723
FPPS	HMDH1	A0A251U7H3	A0A251S4J7	Putative farnesyl pyrophosphate synthase; Belongs to the FPP/GGPP synthase family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.723