(13 nodes) (2021) Pathway engineering for high-yield production of lutein in Escherichia coli. network (Helianthus annuus)

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Your Input:
	PAC	Putative pale cress protein (PAC). (320 aa)
	HMDH2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (559 aa)
	HMDH	3-hydroxy-3-methylglutaryl coenzyme A reductase. (517 aa)
	CYP97A3	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family. (605 aa)
	HMDH1	3-hydroxy-3-methylglutaryl coenzyme A reductase. (595 aa)
	HMDH2-2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (597 aa)
	CRTI	Putative phytoene dehydrogenase, chloroplastic/chromoplastic. (555 aa)
	PRK	Phosphoribulokinase. (407 aa)
	A0A251TUX7	3-hydroxy-3-methylglutaryl coenzyme A reductase. (572 aa)
	LCYB	Putative lycopene beta cyclase, chloroplastic/chromoplastic. (541 aa)
	A0A251U3C3	3-hydroxy-3-methylglutaryl coenzyme A reductase. (590 aa)
	HMCS1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (458 aa)
	MVA1	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (455 aa)

Your Current Organism:

Helianthus annuus

NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251TUX7	CYP97A3	A0A251TUX7	A0A251RSH4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family.	0.426
A0A251TUX7	HMCS1	A0A251TUX7	A0A251UFJ6	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.974
A0A251TUX7	MVA1	A0A251TUX7	A0A251VID0	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.997
A0A251U3C3	CYP97A3	A0A251U3C3	A0A251RSH4	3-hydroxy-3-methylglutaryl coenzyme A reductase.	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family.	0.426
A0A251U3C3	HMCS1	A0A251U3C3	A0A251UFJ6	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.974
A0A251U3C3	MVA1	A0A251U3C3	A0A251VID0	3-hydroxy-3-methylglutaryl coenzyme A reductase.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.997
CRTI	CYP97A3	A0A251SDL9	A0A251RSH4	Putative phytoene dehydrogenase, chloroplastic/chromoplastic.	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family.	0.695
CRTI	LCYB	A0A251SDL9	A0A251TZI8	Putative phytoene dehydrogenase, chloroplastic/chromoplastic.	Putative lycopene beta cyclase, chloroplastic/chromoplastic.	0.864
CRTI	PAC	A0A251SDL9	A0A251VLS4	Putative phytoene dehydrogenase, chloroplastic/chromoplastic.	Putative pale cress protein (PAC).	0.716
CRTI	PRK	A0A251SDL9	A0A251SSJ2	Putative phytoene dehydrogenase, chloroplastic/chromoplastic.	Phosphoribulokinase.	0.468
CYP97A3	A0A251TUX7	A0A251RSH4	A0A251TUX7	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.426
CYP97A3	A0A251U3C3	A0A251RSH4	A0A251U3C3	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.426
CYP97A3	CRTI	A0A251RSH4	A0A251SDL9	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family.	Putative phytoene dehydrogenase, chloroplastic/chromoplastic.	0.695
CYP97A3	LCYB	A0A251RSH4	A0A251TZI8	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family.	Putative lycopene beta cyclase, chloroplastic/chromoplastic.	0.986
CYP97A3	PAC	A0A251RSH4	A0A251VLS4	Putative cytochrome P450, family 97, subfamily A, polypeptide 3; Belongs to the cytochrome P450 family.	Putative pale cress protein (PAC).	0.627
HMCS1	A0A251TUX7	A0A251UFJ6	A0A251TUX7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.974
HMCS1	A0A251U3C3	A0A251UFJ6	A0A251U3C3	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.974
HMCS1	HMDH	A0A251UFJ6	A0A251RS13	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.974
HMCS1	HMDH1	A0A251UFJ6	A0A251S4J7	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.974
HMCS1	HMDH2	A0A251UFJ6	A0A251RRW5	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	3-hydroxy-3-methylglutaryl coenzyme A reductase.	0.974