(22 nodes) (2021) Therapeutic Effects and Safe Uses of Plant-Derived Polyphenolic Compounds in Cardiovascular Diseases: A Review. network (Helianthus annuus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	A0A251SAW8	Putative calcium-binding EF-hand family protein. (171 aa)
	CALM	Putative calmodulin; Belongs to the calmodulin family. (182 aa)
	A0A251T1P8	Putative EF-hand domain pair. (177 aa)
	coxI	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (564 aa)
	A0A251VF41	Putative EF-hand domain pair. (174 aa)
	A0A251V2W6	Putative EF-hand domain pair, Serine/threonine-protein phosphatase with EF-hands; Belongs to the calmodulin family. (149 aa)
	A0A251UPH6	Putative flagellar calcium-binding protein calflagin, EF-hand domain pair. (147 aa)
	A0A251UD38	Putative EF-hand domain pair. (186 aa)
	A0A251U3C3	3-hydroxy-3-methylglutaryl coenzyme A reductase. (590 aa)
	A0A251U398	Putative EF-hand domain pair. (163 aa)
	A0A251TZZ1	Putative EF-hand domain pair. (177 aa)
	A0A251TUX7	3-hydroxy-3-methylglutaryl coenzyme A reductase. (572 aa)
	COX2	Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (352 aa)
	A0A251RNT7	Putative EF-hand domain pair, Serine/threonine-protein phosphatase with EF-hands. (167 aa)
	HMDH2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (559 aa)
	HMDH	3-hydroxy-3-methylglutaryl coenzyme A reductase. (517 aa)
	A0A251RWS8	Putative parvalbumin. (167 aa)
	CALM-2	Putative calmodulin. (149 aa)
	A0A251TFX5	Putative EF-hand domain pair. (151 aa)
	A0A251SVH3	Putative EF-hand domain pair. (71 aa)
	HMDH1	3-hydroxy-3-methylglutaryl coenzyme A reductase. (595 aa)
	HMDH2-2	3-hydroxy-3-methylglutaryl coenzyme A reductase. (597 aa)

Your Current Organism:

Helianthus annuus

NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A251RNT7	CALM-2	A0A251RNT7	A0A251TGR3	Putative EF-hand domain pair, Serine/threonine-protein phosphatase with EF-hands.	Putative calmodulin.	0.445
A0A251RWS8	A0A251SVH3	A0A251RWS8	A0A251SVH3	Putative parvalbumin.	Putative EF-hand domain pair.	0.404
A0A251RWS8	CALM-2	A0A251RWS8	A0A251TGR3	Putative parvalbumin.	Putative calmodulin.	0.414
A0A251SAW8	A0A251SVH3	A0A251SAW8	A0A251SVH3	Putative calcium-binding EF-hand family protein.	Putative EF-hand domain pair.	0.448
A0A251SAW8	CALM-2	A0A251SAW8	A0A251TGR3	Putative calcium-binding EF-hand family protein.	Putative calmodulin.	0.443
A0A251SVH3	A0A251RWS8	A0A251SVH3	A0A251RWS8	Putative EF-hand domain pair.	Putative parvalbumin.	0.404
A0A251SVH3	A0A251SAW8	A0A251SVH3	A0A251SAW8	Putative EF-hand domain pair.	Putative calcium-binding EF-hand family protein.	0.448
A0A251UD38	CALM-2	A0A251UD38	A0A251TGR3	Putative EF-hand domain pair.	Putative calmodulin.	0.441
CALM-2	A0A251RNT7	A0A251TGR3	A0A251RNT7	Putative calmodulin.	Putative EF-hand domain pair, Serine/threonine-protein phosphatase with EF-hands.	0.445
CALM-2	A0A251RWS8	A0A251TGR3	A0A251RWS8	Putative calmodulin.	Putative parvalbumin.	0.414
CALM-2	A0A251SAW8	A0A251TGR3	A0A251SAW8	Putative calmodulin.	Putative calcium-binding EF-hand family protein.	0.443
CALM-2	A0A251UD38	A0A251TGR3	A0A251UD38	Putative calmodulin.	Putative EF-hand domain pair.	0.441
COX2	coxI	A0A1Y3BUU4	W0FGR8	Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.	0.994
coxI	COX2	W0FGR8	A0A1Y3BUU4	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.	Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1.	0.994