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GSH1 GSH1 ATMGL ATMGL A0A251RMP4 A0A251RMP4 A0A251RMR8 A0A251RMR8 A0A251RMU3 A0A251RMU3 LDHA LDHA AK3 AK3 A0A251RRC9 A0A251RRC9 A0A251RSN8 A0A251RSN8 ASP1 ASP1 A0A251RUC4 A0A251RUC4 SPD1 SPD1 A0A251RW65 A0A251RW65 A0A251RY29 A0A251RY29 SERA SERA A0A251RZ67 A0A251RZ67 AGT3 AGT3 A0A251S0H1 A0A251S0H1 A0A251S327 A0A251S327 HMT-1 HMT-1 MTND1 MTND1 AGT2 AGT2 A0A251S6M8 A0A251S6M8 ACCO ACCO A0A251S6Y1 A0A251S6Y1 ACCO3 ACCO3 1A13 1A13 A0A251S7Q1 A0A251S7Q1 CMT3 CMT3 SAHH2 SAHH2 ATSERAT3:2 ATSERAT3:2 AGT2-2 AGT2-2 DCAM DCAM A0A251SJ05 A0A251SJ05 MDHG MDHG METE2 METE2 A0A251SP66 A0A251SP66 A0A251SP99 A0A251SP99 1A11 1A11 LDHA-2 LDHA-2 A0A251SRH7 A0A251SRH7 A0A251SRW3 A0A251SRW3 A0A251SRX6 A0A251SRX6 A0A251SRZ8 A0A251SRZ8 A0A251SX18 A0A251SX18 ATSERAT1:1 ATSERAT1:1 A0A251SZ13 A0A251SZ13 DCAM-2 DCAM-2 A0A251T1Y0 A0A251T1Y0 A0A251T281 A0A251T281 A0A251T2A7 A0A251T2A7 SPD1-3 SPD1-3 A0A251T3N6 A0A251T3N6 MDHG-2 MDHG-2 ACS8 ACS8 A0A251T798 A0A251T798 A0A251T817 A0A251T817 ACCO1 ACCO1 A0A251TAN0 A0A251TAN0 ST1 ST1 DNM1A DNM1A A0A251TE11 A0A251TE11 A0A251TGL8 A0A251TGL8 HMT-2 HMT-2 CYSK1 CYSK1 CYSK CYSK ATMTN1 ATMTN1 ATMTK ATMTK A0A251TKX9 A0A251TKX9 A0A251TLI1 A0A251TLI1 EDA9 EDA9 A0A251TM95 A0A251TM95 A0A251TMX9 A0A251TMX9 A0A251TTM2 A0A251TTM2 A0A251TUC8 A0A251TUC8 A0A251TUE4 A0A251TUE4 A0A251TVQ4 A0A251TVQ4 MTO1 MTO1 A0A251TYL4 A0A251TYL4 MDH MDH MTBC1 MTBC1 SAT5 SAT5 ATCYSD1 ATCYSD1 DCAM-3 DCAM-3 SMTA SMTA DCAM-4 DCAM-4 A0A251U6S1 A0A251U6S1 A0A251U8U5 A0A251U8U5 A0A251U8X0 A0A251U8X0 ASP3 ASP3 ATBCAT-5 ATBCAT-5 METK2 METK2 AK AK A0A251UD42 A0A251UD42 BUD2 BUD2 A0A251UEK1 A0A251UEK1 A0A251UEY4 A0A251UEY4 ACS5 ACS5 1A11-2 1A11-2 CAS1-2 CAS1-2 MEGL MEGL CBL CBL ACS7 ACS7 A0A251UK90 A0A251UK90 MDHC MDHC A0A251UN16 A0A251UN16 METK2-2 METK2-2 ACCO2 ACCO2 A0A251UTE3 A0A251UTE3 PGDH PGDH A0A251UW38 A0A251UW38 A0A251UZR5 A0A251UZR5 1A12 1A12 DNM1B DNM1B A0A251V2K7 A0A251V2K7 ACO1 ACO1 A0A251V9I9 A0A251V9I9 MDH-2 MDH-2 A0A251VGX4 A0A251VGX4 A0A251VH41 A0A251VH41 ASP5 ASP5 AKH AKH CMT1 CMT1 CYSKP CYSKP METK3 METK3 A0A251VNH1 A0A251VNH1 MTNA MTNA HOG1 HOG1 A0A251VRV6 A0A251VRV6 METK3-2 METK3-2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GSH1Putative glutamate--cysteine ligase protein. (520 aa)
ATMGLPutative methionine gamma-lyase. (450 aa)
A0A251RMP4Putative tyrosine/nicotianamine aminotransferase, Pyridoxal phosphate-dependent transferase. (417 aa)
A0A251RMR8Putative C-5 cytosine methyltransferase. (870 aa)
A0A251RMU3Putative bromo adjacent homology (BAH) domain protein. (872 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (351 aa)
AK3Aspartokinase; Belongs to the aspartokinase family. (549 aa)
A0A251RRC9Putative tyrosine transaminase family protein. (426 aa)
A0A251RSN8Putative pyridoxal phosphate-dependent transferase. (497 aa)
ASP1Aspartate aminotransferase. (421 aa)
A0A251RUC4Putative pyridoxal phosphate-dependent transferase. (468 aa)
SPD1Putative spermidine synthase 1; Belongs to the spermidine/spermine synthase family. (332 aa)
A0A251RW65Putative pyridoxal phosphate (PLP)-dependent transferases superfamily protein. (393 aa)
A0A251RY29Putative D-cysteine desulfhydrase. (424 aa)
SERAD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (599 aa)
A0A251RZ67Putative cysteine synthase. (285 aa)
AGT3Putative alanine:glyoxylate aminotransferase 3; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (482 aa)
A0A251S0H1Malate dehydrogenase. (363 aa)
A0A251S327Putative pyridoxal phosphate (PLP)-dependent transferases superfamily protein. (451 aa)
HMT-1Putative homocysteine S-methyltransferase family protein. (338 aa)
MTND11,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (188 aa)
AGT2Putative alanine-glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (474 aa)
A0A251S6M8S-adenosylmethionine decarboxylase proenzyme. (353 aa)
ACCOPutative 1-aminocyclopropane-1-carboxylate oxidase; Belongs to the iron/ascorbate-dependent oxidoreductase family. (318 aa)
A0A251S6Y1Putative pyridoxal phosphate-dependent transferase. (472 aa)
ACCO3Putative 1-aminocyclopropane-1-carboxylate oxidase 3; Belongs to the iron/ascorbate-dependent oxidoreductase family. (319 aa)
1A13Putative 1-aminocyclopropane-1-carboxylate synthase 3. (472 aa)
A0A251S7Q1Putative pyridoxal phosphate-dependent transferase. (472 aa)
CMT3Cytosine-specific methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (855 aa)
SAHH2Adenosylhomocysteinase. (485 aa)
ATSERAT3:2Putative serine acetyltransferase 3,2. (357 aa)
AGT2-2Putative alanine-glyoxylate aminotransferase 2; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (469 aa)
DCAMS-adenosylmethionine decarboxylase proenzyme. (361 aa)
A0A251SJ05Putative glutathione synthase, eukaryotic, Pre-ATP-grasp domain protein. (317 aa)
MDHGMalate dehydrogenase. (352 aa)
METE2Putative 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 2. (832 aa)
A0A251SP66Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (380 aa)
A0A251SP99Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (381 aa)
1A11Putative 1-aminocyclopropane-1-carboxylate synthase 1. (487 aa)
LDHA-2L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (350 aa)
A0A251SRH7Putative cobalamin-independent methionine synthase. (1649 aa)
A0A251SRW3Aspartate aminotransferase. (496 aa)
A0A251SRX6Putative tyrosine transaminase family protein. (412 aa)
A0A251SRZ8S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (437 aa)
A0A251SX18Malate dehydrogenase. (397 aa)
ATSERAT1:1Putative serine acetyltransferase 1,1. (290 aa)
A0A251SZ13Aspartate aminotransferase. (419 aa)
DCAM-2S-adenosylmethionine decarboxylase proenzyme. (355 aa)
A0A251T1Y0Putative semialdehyde dehydrogenase family protein. (380 aa)
A0A251T281Putative HAD hydrolase, subfamily IA. (334 aa)
A0A251T2A7Putative pyridoxal-5'-phosphate-dependent enzyme family protein. (424 aa)
SPD1-3Putative spermidine synthase 1; Belongs to the spermidine/spermine synthase family. (328 aa)
A0A251T3N6Malate dehydrogenase. (347 aa)
MDHG-2Malate dehydrogenase. (358 aa)
ACS8Putative 1-amino-cyclopropane-1-carboxylate synthase 8. (472 aa)
A0A251T798Putative cys/Met metabolism, pyridoxal phosphate-dependent enzyme. (535 aa)
A0A251T817Putative serine O-acetyltransferase. (373 aa)
ACCO1Putative 1-aminocyclopropane-1-carboxylate oxidase 1; Belongs to the iron/ascorbate-dependent oxidoreductase family. (281 aa)
A0A251TAN0Putative serine O-acetyltransferase, Serine acetyltransferase. (349 aa)
ST1Sulfurtransferase. (378 aa)
DNM1ADNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1584 aa)
A0A251TE11Putative nucleoside phosphorylase. (252 aa)
A0A251TGL8Putative pyridoxal phosphate (PLP)-dependent transferases superfamily protein. (458 aa)
HMT-2Putative homocysteine methyltransferase 2. (340 aa)
CYSK1Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (325 aa)
CYSKCysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (325 aa)
ATMTN1Putative methylthioadenosine nucleosidase 1. (260 aa)
ATMTKPutative S-methyl-5-thioribose kinase. (415 aa)
A0A251TKX9Putative tyrosine/nicotianamine aminotransferase, Pyridoxal phosphate-dependent transferase. (412 aa)
A0A251TLI1Malate dehydrogenase. (344 aa)
EDA9D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (596 aa)
A0A251TM95Putative glutathione synthase, eukaryotic. (279 aa)
A0A251TMX9Putative oxoglutarate/iron-dependent dioxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family. (308 aa)
A0A251TTM2Putative pyridoxal phosphate-dependent transferase. (445 aa)
A0A251TUC8Putative pyridoxal phosphate-dependent transferase. (460 aa)
A0A251TUE4Putative spermidine/spermine synthase; Belongs to the spermidine/spermine synthase family. (342 aa)
A0A251TVQ4Putative pyridoxal phosphate-dependent transferase. (208 aa)
MTO1Putative pyridoxal phosphate (PLP)-dependent transferases superfamily protein. (532 aa)
A0A251TYL4Putative bifunctional aspartokinase/homoserine dehydrogenase I. (918 aa)
MDHMalate dehydrogenase. (381 aa)
MTBC1Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1; In the N-terminal section; belongs to the aldolase class II family. MtnB subfamily. (505 aa)
SAT5Putative serine acetyltransferase 5. (301 aa)
ATCYSD1Putative cysteine synthase D1. (283 aa)
DCAM-3S-adenosylmethionine decarboxylase proenzyme. (357 aa)
SMTAPutative selenocysteine Se-methyltransferase. (355 aa)
DCAM-4S-adenosylmethionine decarboxylase proenzyme. (335 aa)
A0A251U6S1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (379 aa)
A0A251U8U5Adenosylhomocysteinase. (485 aa)
A0A251U8X0Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (462 aa)
ASP3Aspartate aminotransferase. (445 aa)
ATBCAT-5Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (413 aa)
METK2S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (453 aa)
AKAspartokinase; Belongs to the aspartokinase family. (557 aa)
A0A251UD42Putative cobalamin-independent methionine synthase. (755 aa)
BUD2S-adenosylmethionine decarboxylase proenzyme. (336 aa)
A0A251UEK1L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (350 aa)
A0A251UEY4Putative glutamate--cysteine ligase, GCS2. (360 aa)
ACS5Putative ACC synthase 5. (460 aa)
1A11-2Putative 1-aminocyclopropane-1-carboxylate synthase 1. (479 aa)
CAS1-2Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (368 aa)
MEGLPutative methionine gamma-lyase. (447 aa)
CBLPutative cystathionine beta-lyase. (495 aa)
ACS7Putative 1-amino-cyclopropane-1-carboxylate synthase 7. (438 aa)
A0A251UK90Putative oxoglutarate/iron-dependent dioxygenase; Belongs to the iron/ascorbate-dependent oxidoreductase family. (313 aa)
MDHCMalate dehydrogenase. (363 aa)
A0A251UN16Putative pyridoxal phosphate-dependent transferase. (206 aa)
METK2-2S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (455 aa)
ACCO2Putative 1-aminocyclopropane-1-carboxylate oxidase 2; Belongs to the iron/ascorbate-dependent oxidoreductase family. (310 aa)
A0A251UTE3Putative 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (311 aa)
PGDHD-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (609 aa)
A0A251UW38Putative pyridoxal-5'-phosphate-dependent enzyme family protein. (428 aa)
A0A251UZR5Putative pyridoxal phosphate-dependent transferase. (441 aa)
1A12Putative 1-aminocyclopropane-1-carboxylate synthase. (472 aa)
DNM1BDNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1578 aa)
A0A251V2K7Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (362 aa)
ACO1Putative ACC oxidase 1; Belongs to the iron/ascorbate-dependent oxidoreductase family. (301 aa)
A0A251V9I9Putative serine O-acetyltransferase. (322 aa)
MDH-2Malate dehydrogenase. (332 aa)
A0A251VGX4Putative pyridoxal phosphate-dependent transferase. (208 aa)
A0A251VH41Malate dehydrogenase. (373 aa)
ASP5Aspartate aminotransferase. (513 aa)
AKHPutative bifunctional aspartokinase/homoserine dehydrogenase, chloroplastic. (899 aa)
CMT1Putative chromomethylase 1. (819 aa)
CYSKPCysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (378 aa)
METK3S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (457 aa)
A0A251VNH1Putative cys/Met metabolism, pyridoxal phosphate-dependent enzyme. (342 aa)
MTNAMethylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (372 aa)
HOG1Adenosylhomocysteinase. (485 aa)
A0A251VRV6Aspartate aminotransferase. (501 aa)
METK3-2S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. (390 aa)
Your Current Organism:
Helianthus annuus
NCBI taxonomy Id: 4232
Other names: H. annuus, Helianthus annuus L., common sunflower
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