Your Input: | |
| | aroE | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (271 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (207 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (220 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa) |
| | dut | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (152 aa) |
| | argA | KEGG: slo:Shew_3478 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. (439 aa) |
| | purD | KEGG: slo:Shew_3413 phosphoribosylamine--glycine ligase; Belongs to the GARS family. (430 aa) |
| | purH | IMP cyclohydrolase; KEGG: slo:Shew_3412 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase. (534 aa) |
| | Ssed_0461 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family. (252 aa) |
| | Ssed_0504 | KEGG: sbl:Sbal_0464 oxidoreductase FAD/NAD(P)-binding domain protein. (236 aa) |
| | fhs | KEGG: slo:Shew_0443 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (570 aa) |
| | Ssed_0676 | KEGG: ilo:IL2163 cysteine synthase. (362 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (431 aa) |
| | alr | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (358 aa) |
| | Ssed_0806 | KEGG: sdn:Sden_3196 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. (197 aa) |
| | argD | KEGG: slo:Shew_0578 acetylornithine and succinylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (405 aa) |
| | Ssed_0817 | KEGG: slo:Shew_0779 aspartate kinase; Belongs to the aspartokinase family. (450 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (383 aa) |
| | Ssed_0937 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (352 aa) |
| | argR | Arginine repressor, ArgR; Regulates arginine biosynthesis genes. (156 aa) |
| | Ssed_0959 | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (160 aa) |
| | purT | Phosphoribosylaminoimidazole carboxylase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (391 aa) |
| | Ssed_1089 | KEGG: slo:Shew_1013 aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (339 aa) |
| | mtnN | Adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'- methylthioribose and S-ribosylhomocysteine, respectively. Belongs to the PNP/UDP phosphorylase family. MtnN subfamily. (230 aa) |
| | Ssed_1122 | KEGG: sfr:Sfri_3408 inosine/uridine-preferring nucleoside hydrolase; Belongs to the IUNH family. (324 aa) |
| | thyA | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (283 aa) |
| | Ssed_1163 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (363 aa) |
| | Ssed_1164 | KEGG: shm:Shewmr7_2915 chorismate mutase. (379 aa) |
| | Ssed_1168 | KEGG: slo:Shew_1072 chorismate mutase. (662 aa) |
| | Ssed_1175 | Aspartate kinase., Homoserine dehydrogenase; KEGG: slo:Shew_1079 aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (821 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (312 aa) |
| | Ssed_1177 | KEGG: slo:Shew_1081 threonine synthase. (426 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (418 aa) |
| | surE | 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (249 aa) |
| | purE | Phosphoribosylaminoimidazole carboxylase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (169 aa) |
| | Ssed_1427 | 5'-nucleotidase; KEGG: slo:Shew_1285 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (581 aa) |
| | tdk | KEGG: sdn:Sden_2536 thymidine kinase. (192 aa) |
| | metAS | Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine; Belongs to the MetA family. (314 aa) |
| | cysS | Cysteine--tRNA ligase; KEGG: slo:Shew_2511 cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (459 aa) |
| | folD | Methylenetetrahydrofolate dehydrogenase (NADP(+)); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa) |
| | Ssed_1559 | KEGG: she:Shewmr4_2477 methionine gamma-lyase. (392 aa) |
| | Ssed_1586 | KEGG: vpa:VP0019 valine-pyruvate aminotransferase. (419 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa) |
| | pdxB | D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (387 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa) |
| | Ssed_1653 | Dihydrofolate synthase; KEGG: she:Shewmr4_1427 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (421 aa) |
| | Ssed_1655 | KEGG: slo:Shew_2303 colicin V production protein. (162 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (504 aa) |
| | trpA | Tryptophan synthase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (272 aa) |
| | trpB | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (407 aa) |
| | trpC | KEGG: slo:Shew_2254 indole-3-glycerol-phosphate synthase., phosphoribosylanthranilate isomerase; Belongs to the TrpC family. (477 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (352 aa) |
| | Ssed_1685 | KEGG: slo:Shew_2252 glutamine amidotransferase of anthranilate synthase. (201 aa) |
| | Ssed_1686 | KEGG: slo:Shew_2251 anthranilate synthase component I. (519 aa) |
| | Ssed_1721 | KEGG: slo:Shew_2382 cysteine synthase A; Belongs to the cysteine synthase/cystathionine beta- synthase family. (322 aa) |
| | purN | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (214 aa) |
| | purM | KEGG: slo:Shew_1513 phosphoribosylformylglycinamidine cyclo-ligase. (345 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) |
| | Ssed_1869 | 3-deoxy-7-phosphoheptulonate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (354 aa) |
| | Ssed_1877 | KEGG: slo:Shew_1555 Glu/Leu/Phe/Val dehydrogenase, dimerisation region; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (344 aa) |
| | Ssed_1879 | KEGG: slo:Shew_1558 adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (455 aa) |
| | deoD | KEGG: vpa:VPA1475 purine nucleoside phosphorylase. (235 aa) |
| | Ssed_1926 | 5'-nucleotidase; KEGG: shm:Shewmr7_2336 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (568 aa) |
| | Ssed_1995 | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (274 aa) |
| | Ssed_2050 | KEGG: slo:Shew_2060 pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (353 aa) |
| | Ssed_2125 | KEGG: slo:Shew_2026 alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa) |
| | Ssed_2247 | KEGG: msm:MSMEG_0277 putative aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (410 aa) |
| | purA-2 | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (418 aa) |
| | pyrF | Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (234 aa) |
| | cmk | KEGG: slo:Shew_1953 cytidylate kinase. (230 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (426 aa) |
| | serC | Phosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (364 aa) |
| | Ssed_2340 | KEGG: slo:Shew_1914 aminotransferase, class I and II. (404 aa) |
| | Ssed_2345 | 5'-nucleotidase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates. (195 aa) |
| | Ssed_2354 | KEGG: slo:Shew_0363 HAD-superfamily hydrolase, subfamily IA, variant 1. (224 aa) |
| | Ssed_2359 | KEGG: shw:Sputw3181_2219 para-aminobenzoate synthase, subunit I. (469 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (294 aa) |
| | Ssed_2443 | KEGG: slo:Shew_1836 uracil-xanthine permease. (408 aa) |
| | pyrD | Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (339 aa) |
| | Ssed_2496 | KEGG: sfr:Sfri_1621 cystathionine beta-lyase. (411 aa) |
| | Ssed_2504 | KEGG: ape:APE_2105.1 uridine phosphorylase. (259 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (299 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (439 aa) |
| | hisC | KEGG: slo:Shew_2199 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (356 aa) |
| | hisB | KEGG: slo:Shew_2200 histidinol-phosphatase; In the N-terminal section; belongs to the histidinol- phosphatase family. (355 aa) |
| | hisH | Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (218 aa) |
| | hisA | KEGG: slo:Shew_2202 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (246 aa) |
| | hisF | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa) |
| | hisI | KEGG: slo:Shew_2204 phosphoribosyl-AMP cyclohydrolase; In the N-terminal section; belongs to the PRA-CH family. (209 aa) |
| | purC | KEGG: slo:Shew_2211 phosphoribosylaminoimidazolesuccinocarboxamide synthase; Belongs to the SAICAR synthetase family. (368 aa) |
| | Ssed_2556 | Hypothetical protein; KEGG: slo:Shew_2211 phosphoribosylaminoimidazolesuccinocarboxamide synthase. (112 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (296 aa) |
| | tmk | dTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (210 aa) |
| | udk | KEGG: slo:Shew_1575 uridine kinase. (211 aa) |
| | Ssed_2669 | KEGG: pin:Ping_2695 5'-nucleotidase domain protein; Belongs to the 5'-nucleotidase family. (569 aa) |
| | Ssed_2694 | KEGG: tde:TDE0870 phosphatase/nucleotidase; Belongs to the 5'-nucleotidase family. (711 aa) |
| | Ssed_2715 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (339 aa) |
| | Ssed_2767 | KEGG: sfr:Sfri_1507 glycosyl transferase, family 3. (390 aa) |
| | Ssed_2772 | KEGG: ppr:PBPRB1892 putative 5'-nucleotidase; Belongs to the 5'-nucleotidase family. (664 aa) |
| | Ssed_2802 | KEGG: vpa:VPA1242 cytosine permease/transport. (421 aa) |
| | Ssed_2803 | N-isopropylammelide isopropylaminohydrolase; KEGG: ppr:PBPRB1375 putative cytosine deaminase. (431 aa) |
| | Ssed_2845 | KEGG: slo:Shew_2228 inosine kinase. (434 aa) |
| | adk-2 | Nucleoside-triphosphate--adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | apt | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (184 aa) |
| | Ssed_2873 | KEGG: slo:Shew_2319 serine O-acetyltransferase. (273 aa) |
| | Ssed_2939 | KEGG: sfr:Sfri_3709 PHP C-terminal domain protein. (246 aa) |
| | cysC | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (228 aa) |
| | cysN | Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (473 aa) |
| | cysD1 | KEGG: slo:Shew_1422 sulfate adenylyltransferase, small subunit. (301 aa) |
| | cysC-2 | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (223 aa) |
| | cysN-2 | Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (469 aa) |
| | cysD2 | KEGG: slo:Shew_1422 sulfate adenylyltransferase, small subunit. (301 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1293 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (525 aa) |
| | guaB | Malate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa) |
| | dapD | KEGG: slo:Shew_2638 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (274 aa) |
| | purU | Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (277 aa) |
| | Ssed_3168 | KEGG: slo:Shew_2642 flavodoxin/nitric oxide synthase. (154 aa) |
| | trpB-2 | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (400 aa) |
| | Ssed_3254 | KEGG: pha:PSHAa1481 hypothetical protein. (467 aa) |
| | Ssed_3268 | KEGG: slo:Shew_2700 antibiotic biosynthesis monooxygenase. (120 aa) |
| | deoD-2 | KEGG: shw:Sputw3181_2368 purine nucleoside phosphorylase. (234 aa) |
| | Ssed_3283 | KEGG: shw:Sputw3181_3244 O-acetylhomoserine/O-acetylserine sulfhydrylase. (429 aa) |
| | Ssed_3310 | KEGG: slo:Shew_2755 conserved hypothetical protein 730. (450 aa) |
| | Ssed_3356 | KEGG: slo:Shew_2795 xanthine/uracil/vitamin C permease. (476 aa) |
| | deoD-3 | KEGG: slo:Shew_2812 purine nucleoside phosphorylase. (236 aa) |
| | carB | KEGG: slo:Shew_2838 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1072 aa) |
| | carA | KEGG: slo:Shew_2839 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (385 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. (271 aa) |
| | Ssed_3414 | Beta-lactamase; KEGG: sdn:Sden_0822 beta-lactamase. (272 aa) |
| | proA | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (424 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (372 aa) |
| | Ssed_3417 | KEGG: slo:Shew_2849 xanthine/uracil/vitamin C permease. (429 aa) |
| | Ssed_3418 | KEGG: slo:Shew_2850 hypothetical protein. (32 aa) |
| | luxS | S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (169 aa) |
| | add | KEGG: vvy:VVA1020 adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (331 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (769 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (344 aa) |
| | deoD-4 | KEGG: vch:VCA0053 purine nucleoside phosphorylase. (236 aa) |
| | Ssed_3654 | KEGG: vvy:VVA0211 uridine phosphorylase. (243 aa) |
| | Ssed_3657 | KEGG: slo:Shew_3055 CMP/dCMP deaminase, zinc-binding. (145 aa) |
| | gcvP | 2-alkenal reductase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (962 aa) |
| | gcvH | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | gcvT | Glycine cleavage system T protein; The glycine cleavage system catalyzes the degradation of glycine. (364 aa) |
| | Ssed_3682 | KEGG: vco:VC0395_0083 purine nucleoside phosphorylase. (138 aa) |
| | Ssed_3739 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1252 aa) |
| | Ssed_3767 | KEGG: pat:Patl_4039 sulfite reductase (NADPH) flavoprotein, alpha chain. (969 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (255 aa) |
| | cysI | Sulfite reductase (NADPH) hemoprotein, beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (587 aa) |
| | Ssed_3807 | Sulfite reductase (NADPH) flavoprotein, alpha chain; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (591 aa) |
| | Ssed_3910 | KEGG: slo:Shew_3142 hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa) |
| | Ssed_3947 | KEGG: slo:Shew_3196 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (411 aa) |
| | Ssed_4039 | KEGG: slo:Shew_0522 5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (296 aa) |
| | Ssed_4040 | Aspartate kinase., Homoserine dehydrogenase; KEGG: slo:Shew_0521 aspartate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. (795 aa) |
| | Ssed_4041 | Cystathionine gamma-synthase; KEGG: shn:Shewana3_3614 O-succinylhomoserine (thiol)-lyase. (386 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (280 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (414 aa) |
| | Ssed_4160 | KEGG: slo:Shew_0294 alanine--glyoxylate transaminase. (380 aa) |
| | ilvE | Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa) |
| | Ssed_4170 | KEGG: pha:PSHAa0645 serine acetyltransferase. (263 aa) |
| | Ssed_4176 | Branched-chain-amino-acid transaminase; KEGG: slo:Shew_0278 branched-chain amino acid aminotransferase. (363 aa) |
| | Ssed_4223 | KEGG: ilo:IL1531 short chain dehydrogenase/reductase family protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (237 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (358 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (171 aa) |
| | argH | KEGG: slo:Shew_0206 argininosuccinate lyase. (457 aa) |
| | argG | KEGG: slo:Shew_0205 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (407 aa) |
| | Ssed_4274 | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (302 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (263 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (326 aa) |
| | Ssed_4277 | KEGG: slo:Shew_0201 acetylornithine deacetylase (ArgE). (383 aa) |
| | cysQ | 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (270 aa) |
| | Ssed_4347 | KEGG: sbl:Sbal_4195 HAD-superfamily hydrolase, subfamily IA, variant 3. (221 aa) |
