73 items (Pygocentrus nattereri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC108437029	Uncharacterized protein. (243 aa)
	LOC108438559	Nuclear receptor subfamily 1, group H, member 5. (492 aa)
	LOC108426775	Adhesion G protein-coupled receptor G1. (616 aa)
	LOC108436245	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (195 aa)
	cav3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (150 aa)
	ripk2	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (576 aa)
	adam17	ADAM metallopeptidase domain 17a. (851 aa)
	pias4	Protein inhibitor of activated STAT, 4a. (505 aa)
	mavs	CARD_2 domain-containing protein. (666 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (486 aa)
	LOC108429038	Tumor necrosis factor receptor superfamily, member 1a. (390 aa)
	ikbke	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (737 aa)
	rnf185	Ring finger protein 185. (191 aa)
	LOC108441862	Cylindromatosis (turban tumor syndrome), like. (730 aa)
	LOC108428766	LSM14A mRNA processing body assembly factor a. (428 aa)
	sigirr	Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain. (429 aa)
	edn1	Endothelin 1. (194 aa)
	ythdf2	YTH N(6)-methyladenosine RNA binding protein 2. (614 aa)
	otud4	Uncharacterized protein. (1364 aa)
	LOC108424063	RAB guanine nucleotide exchange factor (GEF) 1, like. (507 aa)
	LOC108434239	OTU deubiquitinase with linear linkage specificity a. (897 aa)
	supt5h	Transcription elongation factor SPT5. (984 aa)
	samhd1	SAM domain and HD domain 1. (594 aa)
	LOC108428134	Coiled-coil domain containing 3a. (263 aa)
	LOC108438065	HD domain-containing protein. (561 aa)
	socs1	Suppressor of cytokine signaling 1a. (190 aa)
	rabgef1	RAB guanine nucleotide exchange factor (GEF) 1. (502 aa)
	prkn	RBR-type E3 ubiquitin transferase. (590 aa)
	il6st	Interleukin 6 signal transducer. (862 aa)
	ythdf3	YTH N(6)-methyladenosine RNA binding protein 3. (602 aa)
	LOC108441157	Interferon regulatory factor 3. (476 aa)
	LOC108434534	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
	LOC108412092	Uncharacterized protein. (975 aa)
	LOC108410928	ADAM metallopeptidase domain 17b. (805 aa)
	spata2	Spermatogenesis associated 2. (545 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (953 aa)
	LOC108443375	Uncharacterized protein. (414 aa)
	ENSPNAP00000024596	HD domain-containing protein. (622 aa)
	lsm14a	LSM14A mRNA processing body assembly factor b. (480 aa)
	ENSPNAP00000018835	OTU deubiquitinase with linear linkage specificity b. (336 aa)
	mettl3	Methyltransferase like 3; Belongs to the MT-A70-like family. (610 aa)
	ENSPNAP00000019588	HD domain-containing protein. (385 aa)
	cav1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (180 aa)
	adar	Adenosine deaminase RNA specific. (1366 aa)
	ube2k	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
	LOC108427152	Protein inhibitor of activated STAT, 4b. (429 aa)
	med1	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1731 aa)
	ENSPNAP00000024589	HD domain-containing protein. (396 aa)
	dcst1	DC-STAMP domain containing 1. (644 aa)
	fadd	Fas (tnfrsf6)-associated via death domain. (190 aa)
	tbk1	TANK-binding kinase 1. (726 aa)
	trim44	Tripartite motif containing 44. (334 aa)
	LOC108442078	Colony stimulating factor 1b (macrophage). (280 aa)
	parp14	Poly [ADP-ribose] polymerase. (1663 aa)
	traip	TRAF-interacting protein. (442 aa)
	irak1	Interleukin-1 receptor-associated kinase 1. (704 aa)
	LOC108415890	Phe_ZIP domain-containing protein. (261 aa)
	trim32	Tripartite motif containing 32. (665 aa)
	mul1	Mitochondrial E3 ubiquitin protein ligase 1b. (353 aa)
	ecm1	Extracellular matrix protein 1b. (476 aa)
	LOC108415404	Uncharacterized protein. (1170 aa)
	LOC108434694	Uncharacterized protein. (427 aa)
	rnf113a	Ring finger protein 113A. (321 aa)
	LOC108412969	Uncharacterized protein. (435 aa)
	PTPRC	Protein tyrosine phosphatase receptor type C. (1204 aa)
	sharpin	SHANK-associated RH domain interacting protein. (343 aa)
	ENSPNAP00000027867	C1q and TNF related 4. (325 aa)
	LOC108435991	Coiled-coil domain containing 3b. (291 aa)
	OTOP1	Otopetrin 1. (598 aa)
	ENSPNAP00000027231	Apolipoprotein A-Ia. (222 aa)
	LOC108425768	Colony stimulating factor 1a (macrophage). (550 aa)
	ttll12	Tubulin tyrosine ligase-like family, member 12. (637 aa)
	gas6	Uncharacterized protein. (651 aa)

Your Current Organism:

Pygocentrus nattereri

NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPNAP00000018835	sharpin	ENSPNAP00000018835	ENSPNAP00000028139	OTU deubiquitinase with linear linkage specificity b.	SHANK-associated RH domain interacting protein.	0.906
LOC108410928	adam17	ENSPNAP00000016944	ENSPNAP00000011623	ADAM metallopeptidase domain 17b.	ADAM metallopeptidase domain 17a.	0.881
LOC108412092	LOC108426775	ENSPNAP00000016745	ENSPNAP00000010157	Uncharacterized protein.	Adhesion G protein-coupled receptor G1.	0.531
LOC108412092	LOC108429038	ENSPNAP00000016745	ENSPNAP00000013875	Uncharacterized protein.	Tumor necrosis factor receptor superfamily, member 1a.	0.961
LOC108412092	LOC108441862	ENSPNAP00000016745	ENSPNAP00000025012	Uncharacterized protein.	Cylindromatosis (turban tumor syndrome), like.	0.886
LOC108412092	cyld	ENSPNAP00000016745	ENSPNAP00000017301	Uncharacterized protein.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.886
LOC108412092	fadd	ENSPNAP00000016745	ENSPNAP00000023242	Uncharacterized protein.	Fas (tnfrsf6)-associated via death domain.	0.749
LOC108412092	ikbke	ENSPNAP00000016745	ENSPNAP00000025513	Uncharacterized protein.	Inhibitor of nuclear factor kappa B kinase subunit epsilon.	0.927
LOC108412092	ripk2	ENSPNAP00000016745	ENSPNAP00000011295	Uncharacterized protein.	Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains.	0.531
LOC108412092	sharpin	ENSPNAP00000016745	ENSPNAP00000028139	Uncharacterized protein.	SHANK-associated RH domain interacting protein.	0.744
LOC108412092	spata2	ENSPNAP00000016745	ENSPNAP00000017206	Uncharacterized protein.	Spermatogenesis associated 2.	0.880
LOC108412092	tbk1	ENSPNAP00000016745	ENSPNAP00000021267	Uncharacterized protein.	TANK-binding kinase 1.	0.891
LOC108424063	LOC108434534	ENSPNAP00000003135	ENSPNAP00000016576	RAB guanine nucleotide exchange factor (GEF) 1, like.	Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family.	0.412
LOC108424063	rabgef1	ENSPNAP00000003135	ENSPNAP00000006188	RAB guanine nucleotide exchange factor (GEF) 1, like.	RAB guanine nucleotide exchange factor (GEF) 1.	0.659
LOC108424063	ube2k	ENSPNAP00000003135	ENSPNAP00000020582	RAB guanine nucleotide exchange factor (GEF) 1, like.	Ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.	0.412
LOC108426775	LOC108412092	ENSPNAP00000010157	ENSPNAP00000016745	Adhesion G protein-coupled receptor G1.	Uncharacterized protein.	0.531
LOC108426775	LOC108429038	ENSPNAP00000010157	ENSPNAP00000013875	Adhesion G protein-coupled receptor G1.	Tumor necrosis factor receptor superfamily, member 1a.	0.628
LOC108426775	LOC108441862	ENSPNAP00000010157	ENSPNAP00000025012	Adhesion G protein-coupled receptor G1.	Cylindromatosis (turban tumor syndrome), like.	0.571
LOC108426775	cyld	ENSPNAP00000010157	ENSPNAP00000017301	Adhesion G protein-coupled receptor G1.	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family.	0.571
LOC108426775	fadd	ENSPNAP00000010157	ENSPNAP00000023242	Adhesion G protein-coupled receptor G1.	Fas (tnfrsf6)-associated via death domain.	0.810