STRINGSTRING
ENSPNAP00000021980 ENSPNAP00000021980 LOC108419472 LOC108419472 LOC108420573 LOC108420573 LOC108433826 LOC108433826 ENSPNAP00000022791 ENSPNAP00000022791 ENSPNAP00000022830 ENSPNAP00000022830 ENSPNAP00000023571 ENSPNAP00000023571 xrcc4 xrcc4 LOC108410485-2 LOC108410485-2 ENSPNAP00000024710 ENSPNAP00000024710 tmem182 tmem182 dclre1c dclre1c poll poll nhej1 nhej1 ENSPNAP00000025869 ENSPNAP00000025869 brca1 brca1 ENSPNAP00000026198 ENSPNAP00000026198 dntt dntt ube2v2 ube2v2 paxip1 paxip1 ENSPNAP00000001729 ENSPNAP00000001729 LOC108410485 LOC108410485 ENSPNAP00000003136 ENSPNAP00000003136 cnppd1 cnppd1 rnf168 rnf168 LOC108414279 LOC108414279 rnf169 rnf169 LOC108430889 LOC108430889 ENSPNAP00000005929 ENSPNAP00000005929 rnf8 rnf8 slc23a3 slc23a3 atm atm herc2 herc2 LOC108414247 LOC108414247 ankrd11 ankrd11 LOC108417104 LOC108417104 ENSPNAP00000007863 ENSPNAP00000007863 ENSPNAP00000007876 ENSPNAP00000007876 LOC108417023 LOC108417023 xrcc6 xrcc6 LOC108416587 LOC108416587 ENSPNAP00000008783 ENSPNAP00000008783 LOC108429172 LOC108429172 ENSPNAP00000009494 ENSPNAP00000009494 nsd2 nsd2 rif1 rif1 ENSPNAP00000010953 ENSPNAP00000010953 pias4 pias4 ENSPNAP00000011941 ENSPNAP00000011941 ENSPNAP00000012483 ENSPNAP00000012483 ENSPNAP00000012622 ENSPNAP00000012622 ENSPNAP00000013605 ENSPNAP00000013605 LOC108437842 LOC108437842 mdc1 mdc1 ENSPNAP00000015493 ENSPNAP00000015493 tdp2 tdp2 LOC108427799 LOC108427799 LOC108427738 LOC108427738 LOC108418248 LOC108418248 LOC108418150 LOC108418150 ENSPNAP00000018190 ENSPNAP00000018190 LOC108417841 LOC108417841 ENSPNAP00000018754 ENSPNAP00000018754 polm polm LOC108418992 LOC108418992 LOC108418988 LOC108418988 LOC108422227 LOC108422227 ENSPNAP00000019271 ENSPNAP00000019271 tdp1 tdp1 ENSPNAP00000019589 ENSPNAP00000019589 LOC108438310 LOC108438310 LOC108417709 LOC108417709 ENSPNAP00000020073 ENSPNAP00000020073 LOC108416669 LOC108416669 ENSPNAP00000020106 ENSPNAP00000020106 LOC108416132 LOC108416132 ENSPNAP00000020276 ENSPNAP00000020276 LOC108416669-2 LOC108416669-2 nbn nbn ENSPNAP00000020334 ENSPNAP00000020334 ENSPNAP00000020371 ENSPNAP00000020371 rad50 rad50 ENSPNAP00000020520 ENSPNAP00000020520 LOC108420155 LOC108420155 LOC108427152 LOC108427152 ENSPNAP00000020643 ENSPNAP00000020643 ENSPNAP00000020700 ENSPNAP00000020700 LIG4 LIG4 ENSPNAP00000021371 ENSPNAP00000021371 LOC108415447 LOC108415447 LOC108422872 LOC108422872 ENSPNAP00000021584 ENSPNAP00000021584 ENSPNAP00000037477 ENSPNAP00000037477 ENSPNAP00000037462 ENSPNAP00000037462 LOC108416669-3 LOC108416669-3 ENSPNAP00000037449 ENSPNAP00000037449 ENSPNAP00000037077 ENSPNAP00000037077 LOC108413812 LOC108413812 ENSPNAP00000036865 ENSPNAP00000036865 LOC108421775 LOC108421775 ENSPNAP00000035796 ENSPNAP00000035796 LOC108419246 LOC108419246 ENSPNAP00000034399 ENSPNAP00000034399 ENSPNAP00000034115 ENSPNAP00000034115 ENSPNAP00000033142 ENSPNAP00000033142 tp53bp1 tp53bp1 prkdc prkdc ube2n ube2n mre11 mre11 ENSPNAP00000031130 ENSPNAP00000031130 LOC108415449 LOC108415449 ankrd12 ankrd12 xrcc5 xrcc5 ENSPNAP00000028475 ENSPNAP00000028475 ENSPNAP00000028302 ENSPNAP00000028302 LOC108416827 LOC108416827 ENSPNAP00000027502 ENSPNAP00000027502 LOC108414247-2 LOC108414247-2 LOC108417204 LOC108417204 ENSPNAP00000027130 ENSPNAP00000027130 LOC108419634 LOC108419634 ENSPNAP00000021833 ENSPNAP00000021833 LOC108422628 LOC108422628 ENSPNAP00000021972 ENSPNAP00000021972
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSPNAP00000021980annotation not available (67 aa)
LOC108419472Histone domain-containing protein; Belongs to the histone H2B family. (80 aa)
LOC108420573Histone H2B-like. (118 aa)
LOC108433826Tyrosyl-DNA phosphodiesterase 2b. (368 aa)
ENSPNAP00000022791annotation not available (114 aa)
ENSPNAP00000022830Histone H2A; Belongs to the histone H2A family. (139 aa)
ENSPNAP00000023571Histone H2A; Belongs to the histone H2A family. (149 aa)
xrcc4X-ray repair complementing defective repair in Chinese hamster cells 4. (338 aa)
LOC108410485-2Histone H2B-like. (124 aa)
ENSPNAP00000024710Histone H2B; Belongs to the histone H2B family. (117 aa)
tmem182Transmembrane protein 182a. (240 aa)
dclre1cDNA cross-link repair 1C, PSO2 homolog (S. cerevisiae). (693 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (563 aa)
nhej1Nonhomologous end-joining factor 1. (315 aa)
ENSPNAP00000025869annotation not available (114 aa)
brca1Uncharacterized protein. (1583 aa)
ENSPNAP00000026198Histone H2A; Belongs to the histone H2A family. (150 aa)
dnttDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (483 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
paxip1PAX interacting (with transcription-activation domain) protein 1. (1108 aa)
ENSPNAP00000001729Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (96 aa)
LOC108410485Histone H2B; Belongs to the histone H2B family. (124 aa)
ENSPNAP00000003136Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (151 aa)
cnppd1Cyclin Pas1/PHO80 domain containing 1. (435 aa)
rnf168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (467 aa)
LOC108414279Histone H2A; Belongs to the histone H2A family. (136 aa)
rnf169Ring finger protein 169. (646 aa)
LOC108430889Uncharacterized protein. (251 aa)
ENSPNAP00000005929Reverse transcriptase domain-containing protein. (452 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (515 aa)
slc23a3Solute carrier family 23 member 3. (584 aa)
atmNon-specific serine/threonine protein kinase. (3080 aa)
herc2HECT and RLD domain containing E3 ubiquitin protein ligase 2. (4770 aa)
LOC108414247Histone H2A; Belongs to the histone H2A family. (128 aa)
ankrd11Ankyrin repeat domain 11. (2829 aa)
LOC108417104Histone domain-containing protein; Belongs to the histone H2B family. (91 aa)
ENSPNAP00000007863Histone H2A; Belongs to the histone H2A family. (138 aa)
ENSPNAP00000007876Histone H2B; Belongs to the histone H2B family. (109 aa)
LOC108417023Histone H2A; Belongs to the histone H2A family. (141 aa)
xrcc6X-ray repair complementing defective repair in Chinese hamster cells 6. (554 aa)
LOC108416587Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (102 aa)
ENSPNAP00000008783Reverse transcriptase domain-containing protein. (411 aa)
LOC108429172Histone H2B; Belongs to the histone H2B family. (117 aa)
ENSPNAP00000009494Histone H2B; Belongs to the histone H2B family. (89 aa)
nsd2Nuclear receptor binding SET domain protein 2. (1379 aa)
rif1Replication timing regulatory factor 1. (2383 aa)
ENSPNAP00000010953Reverse transcriptase domain-containing protein. (350 aa)
pias4Protein inhibitor of activated STAT, 4a. (505 aa)
ENSPNAP00000011941Histone H2A; Belongs to the histone H2A family. (126 aa)
ENSPNAP00000012483Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (114 aa)
ENSPNAP00000012622Histone H2B; Belongs to the histone H2B family. (114 aa)
ENSPNAP00000013605Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (92 aa)
LOC108437842Transmembrane protein 182b. (271 aa)
mdc1Uncharacterized protein. (2154 aa)
ENSPNAP00000015493Histone H2B; Belongs to the histone H2B family. (74 aa)
tdp2Tyrosyl-DNA phosphodiesterase 2a. (393 aa)
LOC108427799Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (541 aa)
LOC108427738Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (535 aa)
LOC108418248Histone H2B 1/2-like. (67 aa)
LOC108418150Histone domain-containing protein; Belongs to the histone H2B family. (108 aa)
ENSPNAP00000018190annotation not available (64 aa)
LOC108417841Histone H2B-like. (117 aa)
ENSPNAP00000018754Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (78 aa)
polmDNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (473 aa)
LOC108418992Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (91 aa)
LOC108418988Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
LOC108422227Histone H2B-like. (91 aa)
ENSPNAP00000019271annotation not available (75 aa)
tdp1Tyrosyl-DNA phosphodiesterase 1. (572 aa)
ENSPNAP00000019589annotation not available (67 aa)
LOC108438310Si:dkey-217f16.6. (1656 aa)
LOC108417709Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (85 aa)
ENSPNAP00000020073annotation not available (63 aa)
LOC108416669Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
ENSPNAP00000020106Uncharacterized protein. (108 aa)
LOC108416132Histone H4. (103 aa)
ENSPNAP00000020276Si:dkey-23a13.12. (62 aa)
LOC108416669-2Histone H4. (103 aa)
nbnNibrin. (884 aa)
ENSPNAP00000020334annotation not available (77 aa)
ENSPNAP00000020371annotation not available (64 aa)
rad50RAD50 homolog, double strand break repair protein. (1312 aa)
ENSPNAP00000020520annotation not available (64 aa)
LOC108420155Histone H4-like. (101 aa)
LOC108427152Protein inhibitor of activated STAT, 4b. (429 aa)
ENSPNAP00000020643Reverse transcriptase domain-containing protein. (550 aa)
ENSPNAP00000020700annotation not available (67 aa)
LIG4DNA ligase. (905 aa)
ENSPNAP00000021371annotation not available (74 aa)
LOC108415447Histone H2A; Belongs to the histone H2A family. (128 aa)
LOC108422872Histone H4-like. (79 aa)
ENSPNAP00000021584annotation not available (64 aa)
ENSPNAP00000037477annotation not available (64 aa)
ENSPNAP00000037462annotation not available (67 aa)
LOC108416669-3Histone H4. (103 aa)
ENSPNAP00000037449annotation not available (67 aa)
ENSPNAP00000037077annotation not available (78 aa)
LOC108413812Histone H2B. (124 aa)
ENSPNAP00000036865Ligase IV, DNA, ATP-dependent. (905 aa)
LOC108421775Histone H2B 1/2-like. (67 aa)
ENSPNAP00000035796annotation not available (67 aa)
LOC108419246Histone H2B; Belongs to the histone H2B family. (124 aa)
ENSPNAP00000034399Histone H2B; Belongs to the histone H2B family. (112 aa)
ENSPNAP00000034115annotation not available (64 aa)
ENSPNAP00000033142Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (99 aa)
tp53bp1Tumor protein p53 binding protein, 1. (1804 aa)
prkdcProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4091 aa)
ube2nUbiquitin-conjugating enzyme E2Na; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (598 aa)
ENSPNAP00000031130Uncharacterized protein; Belongs to the histone H2A family. (232 aa)
LOC108415449Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (105 aa)
ankrd12Ankyrin repeat domain 12. (2032 aa)
xrcc5X-ray repair complementing defective repair in Chinese hamster cells 5. (736 aa)
ENSPNAP00000028475Histone H2B; Belongs to the histone H2B family. (126 aa)
ENSPNAP00000028302Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (94 aa)
LOC108416827Histone H2A-like. (141 aa)
ENSPNAP00000027502Histone H2A; Belongs to the histone H2A family. (114 aa)
LOC108414247-2Histone H2A-like. (128 aa)
LOC108417204Histone H4-like. (96 aa)
ENSPNAP00000027130Histone H2B; Belongs to the histone H2B family. (114 aa)
LOC108419634Histone H2B 1/2-like. (67 aa)
ENSPNAP00000021833Uncharacterized protein. (322 aa)
LOC108422628Histone H2B-like. (67 aa)
ENSPNAP00000021972annotation not available (67 aa)
Your Current Organism:
Pygocentrus nattereri
NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha
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