(135 nodes) Hippo signaling pathway - multiple species network (Pygocentrus nattereri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pcdh17	Protocadherin 17. (1135 aa)
	LOC108443897	Chloride channel protein. (768 aa)
	LOC108441590	TEA domain family member 3 b. (417 aa)
	LOC108442942	Cadherin-related family member 1a. (863 aa)
	ENSPNAP00000002582	Si:dkey-1m11.6. (1665 aa)
	LOC108441494	TEA domain family member 1a. (390 aa)
	ENSPNAP00000005139	Cadherin_2 domain-containing protein. (115 aa)
	ENSPNAP00000005144	Uncharacterized protein. (772 aa)
	pcdh7	Protocadherin 7b. (1241 aa)
	LOC108430951	Protocadherin b. (808 aa)
	ENSPNAP00000005196	Uncharacterized protein. (856 aa)
	LOC108430924	Protocadherin 2 alpha a 15. (795 aa)
	ENSPNAP00000005265	Uncharacterized protein. (226 aa)
	ENSPNAP00000005310	CA domain-containing protein. (259 aa)
	LOC108430948	Uncharacterized protein. (943 aa)
	ENSPNAP00000005498	Protocadherin 2 alpha c. (1229 aa)
	ENSPNAP00000005522	Uncharacterized protein. (691 aa)
	PCDH10	Protocadherin 10. (1089 aa)
	pcdh18	Protocadherin 18b. (1159 aa)
	ENSPNAP00000005680	Uncharacterized protein. (94 aa)
	cdhr2	Uncharacterized protein. (1301 aa)
	LOC108413018	Protocadherin 18a. (1111 aa)
	sav1	Salvador family WW domain containing protein 1. (405 aa)
	lats1	Large tumor suppressor kinase 1. (1110 aa)
	frmd6	FERM domain containing 6. (609 aa)
	LOC108440819	Ras association domain family member 2a. (321 aa)
	LOC108428003	Chloride channel protein. (808 aa)
	ENSPNAP00000008747	Cadherin_2 domain-containing protein. (155 aa)
	ENSPNAP00000008819	Uncharacterized protein. (260 aa)
	RASSF1	Ras association domain family member 1. (367 aa)
	tead1	TEA domain family member 1b. (433 aa)
	LOC108442966	Si:ch211-186j3.6; Cadherins are calcium-dependent cell adhesion proteins. (2811 aa)
	cdh23	Cadherin-related 23. (3136 aa)
	CNMD	Chondromodulin. (312 aa)
	PCDH8	Protocadherin 8. (989 aa)
	LOC108434738	Uncharacterized protein. (979 aa)
	wwc1	WW and C2 domain containing 1. (1118 aa)
	rassf2	Ras association domain family member 2b. (310 aa)
	CDHR1	Cadherin related family member 1. (881 aa)
	LOC108439533	MOB kinase activator 1Bb. (264 aa)
	LOC108438484	MOB kinase activator 1A. (216 aa)
	LOC108441695	FAT atypical cadherin 1a. (4626 aa)
	LOC108438972	Dachsous cadherin-related 1b. (3261 aa)
	LOC108432272	Cadherin 7a; Cadherins are calcium-dependent cell adhesion proteins. (800 aa)
	LIMD1	LIM domains containing 1. (599 aa)
	ajuba	Ajuba LIM protein. (695 aa)
	LOC108437817	Uncharacterized protein. (951 aa)
	LOC108437325	Si:dkey-22o22.2; Cadherins are calcium-dependent cell adhesion proteins. (2749 aa)
	ENSPNAP00000016368	Protocadherin 1 alpha 6. (479 aa)
	ENSPNAP00000016544	Protocadherin 1 gamma 1. (891 aa)
	ENSPNAP00000016582	Protocadherin 1 gamma 1. (1048 aa)
	ENSPNAP00000016592	Protocadherin 1 gamma 1. (960 aa)
	ENSPNAP00000016639	Cadherin_2 domain-containing protein. (145 aa)
	ENSPNAP00000016653	Uncharacterized protein. (911 aa)
	ENSPNAP00000016687	Uncharacterized protein. (586 aa)
	ENSPNAP00000016691	Uncharacterized protein. (286 aa)
	CDH8	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins. (801 aa)
	ENSPNAP00000017116	Uncharacterized protein. (757 aa)
	ENSPNAP00000017141	Uncharacterized protein. (289 aa)
	ENSPNAP00000017149	Uncharacterized protein. (865 aa)
	ENSPNAP00000017216	Uncharacterized protein. (802 aa)
	ENSPNAP00000017291	Uncharacterized protein. (805 aa)
	ENSPNAP00000017328	Protocadherin 1 gamma 22. (972 aa)
	ENSPNAP00000017360	CA domain-containing protein. (205 aa)
	ENSPNAP00000017383	Cadherin_2 domain-containing protein. (201 aa)
	LOC108437803	Uncharacterized protein. (945 aa)
	LOC108429458	TEA domain-containing protein. (366 aa)
	wtip	WT1 interacting protein. (640 aa)
	LOC108417465	Protocadherin 11. (1229 aa)
	ENSPNAP00000019356	Uncharacterized protein. (892 aa)
	LOC108440501	Uncharacterized protein. (973 aa)
	LOC108440500	Protocadherin 8. (947 aa)
	ENSPNAP00000019502	Cadherin_2 domain-containing protein. (115 aa)
	ENSPNAP00000019516	Uncharacterized protein. (482 aa)
	LOC108415078	Protocadherin 7a. (1330 aa)
	ENSPNAP00000019569	Uncharacterized protein. (794 aa)
	ENSPNAP00000019650	Uncharacterized protein. (975 aa)
	ENSPNAP00000019849	Uncharacterized protein. (698 aa)
	ENSPNAP00000019853	Protocadherin 2 gamma 17. (915 aa)
	LOC108438829	Uncharacterized protein. (410 aa)
	LOC108438833	Protocadherin 2 gamma 17. (784 aa)
	LOC108438834	Protocadherin 2 gamma 17. (871 aa)
	ENSPNAP00000019956	Uncharacterized protein. (826 aa)
	LOC108438827	Uncharacterized protein. (964 aa)
	LOC108426497	Si:ch73-205h11.1. (336 aa)
	LOC108415737	Uncharacterized protein. (919 aa)
	ENSPNAP00000021455	Cadherin_2 domain-containing protein. (75 aa)
	cdh11	Cadherin 11, type 2, OB-cadherin (osteoblast); Cadherins are calcium-dependent cell adhesion proteins. (799 aa)
	rassf4	Ras association domain family member 4a. (322 aa)
	LOC108433795	Dachsous cadherin-related 1a. (3286 aa)
	ENSPNAP00000024398	Si:dkey-1m11.5. (597 aa)
	lats2	Large tumor suppressor kinase 2. (1145 aa)
	LOC108430952	Si:ch73-233f7.1. (998 aa)
	LOC108430927	Si:ch73-379j16.2. (790 aa)
	ENSPNAP00000026201	Uncharacterized protein. (234 aa)
	ENSPNAP00000026217	Uncharacterized protein. (837 aa)
	ENSPNAP00000026236	Protocadherin 2 alpha b 5. (897 aa)
	ENSPNAP00000026279	Uncharacterized protein. (625 aa)
	LOC108434858	Chloride channel protein. (822 aa)
	ENSPNAP00000028473	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins. (664 aa)
	pcdh9	Protocadherin 9. (1238 aa)
	ENSPNAP00000028643	Uncharacterized protein. (278 aa)
	mob1b	MOB kinase activator 1Ba. (216 aa)
	pcdh19	Protocadherin 19. (1107 aa)
	yap1	Yes-associated protein 1. (479 aa)
	dchs2	Uncharacterized protein. (3258 aa)
	clcn3	Chloride channel protein. (752 aa)
	fat1	FAT atypical cadherin 1b. (4516 aa)
	LOC108438453	Protocadherin 1b. (1157 aa)
	LOC108437809	Protocadherin 1a. (1191 aa)
	wwtr1	WW domain containing transcription regulator 1. (451 aa)
	ENSPNAP00000033582	Uncharacterized protein. (792 aa)
	ENSPNAP00000033586	Uncharacterized protein. (337 aa)
	ENSPNAP00000033635	Uncharacterized protein. (780 aa)
	ENSPNAP00000033733	Uncharacterized protein. (880 aa)
	PCDHAC2	Protocadherin alpha subfamily C, 2. (984 aa)
	ENSPNAP00000033928	Uncharacterized protein. (792 aa)
	fat4	FAT atypical cadherin 4. (4972 aa)
	ENSPNAP00000034167	Uncharacterized protein. (711 aa)
	ENSPNAP00000034204	Cadherin_2 domain-containing protein. (116 aa)
	ENSPNAP00000034286	Cadherin_2 domain-containing protein. (85 aa)
	ENSPNAP00000034305	Uncharacterized protein. (1291 aa)
	ENSPNAP00000034367	Uncharacterized protein. (267 aa)
	ENSPNAP00000034386	Protocadherin 1 gamma c 5. (812 aa)
	ENSPNAP00000034418	Uncharacterized protein. (269 aa)
	fat2	FAT atypical cadherin 2. (4305 aa)
	wwc3	WWC family member 3. (1151 aa)
	LOC108415085	FERM domain containing 1. (512 aa)
	LOC108440502	Chondromodulin. (332 aa)
	ENSPNAP00000035677	Uncharacterized protein. (282 aa)
	PCDHGB4	Protocadherin gamma subfamily B, 4. (799 aa)
	ENSPNAP00000035860	CA domain-containing protein. (360 aa)
	LOC108438831	Uncharacterized protein. (819 aa)
	rassf6	Ras association domain family member 6. (348 aa)
	LOC108443914	Ras association domain family member 1. (362 aa)

Your Current Organism:

Pygocentrus nattereri

NCBI taxonomy Id: 42514
Other names: P. nattereri, Serrasalmus nattereri, red piranha, red-bellied piranha

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH8	LOC108441695	ENSPNAP00000016896	ENSPNAP00000014440	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.	FAT atypical cadherin 1a.	0.485
CDH8	fat1	ENSPNAP00000016896	ENSPNAP00000032455	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.	FAT atypical cadherin 1b.	0.485
CDH8	fat2	ENSPNAP00000016896	ENSPNAP00000035040	Cadherin 8; Cadherins are calcium-dependent cell adhesion proteins.	FAT atypical cadherin 2.	0.485
CDHR1	LOC108441695	ENSPNAP00000013016	ENSPNAP00000014440	Cadherin related family member 1.	FAT atypical cadherin 1a.	0.485
CDHR1	fat1	ENSPNAP00000013016	ENSPNAP00000032455	Cadherin related family member 1.	FAT atypical cadherin 1b.	0.485
CDHR1	fat2	ENSPNAP00000013016	ENSPNAP00000035040	Cadherin related family member 1.	FAT atypical cadherin 2.	0.485
ENSPNAP00000002582	LOC108441695	ENSPNAP00000002582	ENSPNAP00000014440	Si:dkey-1m11.6.	FAT atypical cadherin 1a.	0.520
ENSPNAP00000002582	fat1	ENSPNAP00000002582	ENSPNAP00000032455	Si:dkey-1m11.6.	FAT atypical cadherin 1b.	0.520
ENSPNAP00000002582	fat2	ENSPNAP00000002582	ENSPNAP00000035040	Si:dkey-1m11.6.	FAT atypical cadherin 2.	0.520
ENSPNAP00000005265	ENSPNAP00000034418	ENSPNAP00000005265	ENSPNAP00000034418	Uncharacterized protein.	Uncharacterized protein.	0.537
ENSPNAP00000005265	LOC108438829	ENSPNAP00000005265	ENSPNAP00000019900	Uncharacterized protein.	Uncharacterized protein.	0.410
ENSPNAP00000005310	ENSPNAP00000034418	ENSPNAP00000005310	ENSPNAP00000034418	CA domain-containing protein.	Uncharacterized protein.	0.474
ENSPNAP00000005680	LOC108441695	ENSPNAP00000005680	ENSPNAP00000014440	Uncharacterized protein.	FAT atypical cadherin 1a.	0.485
ENSPNAP00000005680	fat1	ENSPNAP00000005680	ENSPNAP00000032455	Uncharacterized protein.	FAT atypical cadherin 1b.	0.485
ENSPNAP00000005680	fat2	ENSPNAP00000005680	ENSPNAP00000035040	Uncharacterized protein.	FAT atypical cadherin 2.	0.485
ENSPNAP00000016691	ENSPNAP00000034418	ENSPNAP00000016691	ENSPNAP00000034418	Uncharacterized protein.	Uncharacterized protein.	0.413
ENSPNAP00000024398	LOC108441695	ENSPNAP00000024398	ENSPNAP00000014440	Si:dkey-1m11.5.	FAT atypical cadherin 1a.	0.520
ENSPNAP00000024398	fat1	ENSPNAP00000024398	ENSPNAP00000032455	Si:dkey-1m11.5.	FAT atypical cadherin 1b.	0.520
ENSPNAP00000024398	fat2	ENSPNAP00000024398	ENSPNAP00000035040	Si:dkey-1m11.5.	FAT atypical cadherin 2.	0.520
ENSPNAP00000028473	LOC108441695	ENSPNAP00000028473	ENSPNAP00000014440	Uncharacterized protein; Cadherins are calcium-dependent cell adhesion proteins.	FAT atypical cadherin 1a.	0.485