STRINGSTRING
arc1 arc1 Arpc4 Arpc4 MYO2 MYO2 CHS8 CHS8 DNF11_0681 DNF11_0681 rid1 rid1 DNF11_0781 DNF11_0781 DNF11_0108 DNF11_0108 DNF11_0559 DNF11_0559 TPM2 TPM2 DNF11_0358 DNF11_0358 arc2 arc2 IMA1 IMA1 DNF11_1132 DNF11_1132 DNF11_2065 DNF11_2065 DNF11_2000 DNF11_2000 EDE1 EDE1 MYO1 MYO1 DNF11_2425 DNF11_2425 actr2 actr2 crn1 crn1 sla1 sla1 end4 end4 COF1 COF1 cap-1 cap-1 DNF11_2973 DNF11_2973 PAN1 PAN1 DNF11_3033 DNF11_3033 rng2 rng2 GMFB GMFB SAC6 SAC6 FYV4 FYV4 arc3 arc3 BNI1 BNI1 myo2 myo2 Arpc5 Arpc5 psidin psidin CAPZB CAPZB DBNL DBNL act2 act2 BUD6 BUD6 cap1 cap1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
arc1Actin-related protein 2/3 complex subunit 1. (429 aa)
Arpc4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
MYO2Myosin-2; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1522 aa)
CHS8Chitin synthase 8; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1826 aa)
DNF11_0681FRG1-like family protein. (250 aa)
rid1GTPase-binding protein rid1. (393 aa)
DNF11_0781SH3 domain-containing protein. (462 aa)
DNF11_0108Uncharacterized protein. (588 aa)
DNF11_0559Uncharacterized protein. (196 aa)
TPM2Tropomyosin-2. (161 aa)
DNF11_0358Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology. (862 aa)
arc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (309 aa)
IMA1Integral inner nuclear membrane protein ima1. (394 aa)
DNF11_1132WH2 domain-containing protein. (355 aa)
DNF11_2065Uncharacterized protein. (655 aa)
DNF11_2000Ysc84 domain-containing protein. (293 aa)
EDE1EH domain-containing and endocytosis protein 1. (1015 aa)
MYO1Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1252 aa)
DNF11_2425Phosducin-like protein C2A9.09. (215 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (392 aa)
crn1Coronin; Belongs to the WD repeat coronin family. (634 aa)
sla1Actin cytoskeleton-regulatory complex protein sla1. (1001 aa)
end4Endocytosis protein end4. (1489 aa)
COF1Cofilin; Belongs to the actin-binding proteins ADF family. (139 aa)
cap-1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (358 aa)
DNF11_2973Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
PAN1Actin cytoskeleton-regulatory complex protein PAN1. (1102 aa)
DNF11_3033Uncharacterized protein. (1002 aa)
rng2Ras GTPase-activating-like protein rng2. (1582 aa)
GMFBGlia maturation factor beta. (138 aa)
SAC6Fimbrin. (615 aa)
FYV4Protein FYV4, mitochondrial. (140 aa)
arc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (177 aa)
BNI1Protein BNI1. (1640 aa)
myo2Myosin type-2 heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1326 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (156 aa)
psidinPhagocyte signaling-impaired protein. (791 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (284 aa)
DBNLDrebrin-like protein. (607 aa)
act2Actin-related protein 3; Belongs to the actin family. (436 aa)
BUD6Bud site selection protein 6. (841 aa)
cap1Adenylyl cyclase-associated protein; Belongs to the CAP family. (491 aa)
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
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