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CAPZB CAPZB act2 act2 dip1 dip1 BUD6 BUD6 RRD1 RRD1 cap1 cap1 hob3 hob3 psidin psidin Arpc5 Arpc5 PAC1_2 PAC1_2 myo2 myo2 CKAP5 CKAP5 BNI1 BNI1 ARHGDIA ARHGDIA cdc4 cdc4 Pxn Pxn CDC42 CDC42 RGD2 RGD2 TBCD TBCD spt20 spt20 nuf2 nuf2 DNF11_2000 DNF11_2000 DNF11_2124 DNF11_2124 arc1 arc1 CBK1 CBK1 TUB4 TUB4 CDC11 CDC11 kif11_2 kif11_2 MYO1 MYO1 actr2 actr2 CLTC CLTC crn1 crn1 NPL4 NPL4 DNF11_2366 DNF11_2366 ask1 ask1 DNF11_0627 DNF11_0627 nudA nudA rhoA rhoA WRAP73 WRAP73 sla1 sla1 end4 end4 tea4 tea4 COF1 COF1 Cdc42bpb Cdc42bpb rga1 rga1 rho1 rho1 DNF11_2973 DNF11_2973 DNF11_3033 DNF11_3033 ppk30 ppk30 plo1 plo1 scd1 scd1 DYNC1H1 DYNC1H1 CDC10 CDC10 MPS1 MPS1 alp6 alp6 wat1 wat1 alp4 alp4 ent1 ent1 DNF11_3605 DNF11_3605 SAC6 SAC6 cdc37 cdc37 TUB1 TUB1 ZNF207 ZNF207 tbce tbce DNF11_1887 DNF11_1887 ark1 ark1 arc3 arc3 CLIP1 CLIP1 RRD2 RRD2 nudE nudE Arpc4 Arpc4 vps1 vps1 RVS167 RVS167 kif11_1 kif11_1 SIW14 SIW14 DNF11_0390 DNF11_0390 rid1 rid1 BIM1 BIM1 DNF11_0781 DNF11_0781 DCTN1 DCTN1 TUB-B TUB-B bimC bimC DNF11_0108 DNF11_0108 DNF11_0272 DNF11_0272 STRIP1 STRIP1 DNF11_1101 DNF11_1101 cdc31 cdc31 DNF11_0866 DNF11_0866 TPM2 TPM2 CDC14 CDC14 klp6 klp6 TUB-1A TUB-1A ase1 ase1 Dync1li2 Dync1li2 arc2 arc2 DNF11_1132 DNF11_1132 CDC48 CDC48 imp2 imp2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (284 aa)
act2Actin-related protein 3; Belongs to the actin family. (436 aa)
dip1Protein dip1. (606 aa)
BUD6Bud site selection protein 6. (841 aa)
RRD1Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (327 aa)
cap1Adenylyl cyclase-associated protein; Belongs to the CAP family. (491 aa)
hob3Protein hob3. (262 aa)
psidinPhagocyte signaling-impaired protein. (791 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (156 aa)
PAC1_2Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (428 aa)
myo2Myosin type-2 heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1326 aa)
CKAP5Cytoskeleton-associated protein 5. (1825 aa)
BNI1Protein BNI1. (1640 aa)
ARHGDIARho GDP-dissociation inhibitor 1. (219 aa)
cdc4Myosin regulatory light chain cdc4. (140 aa)
PxnPaxillin. (350 aa)
CDC42Cell division control protein 42. (191 aa)
RGD2Rho-GTPase-activating protein RGD2. (973 aa)
TBCDTubulin-specific chaperone D. (1021 aa)
spt20SAGA complex subunit spt20. (471 aa)
nuf2Kinetochore protein nuf2. (443 aa)
DNF11_2000Ysc84 domain-containing protein. (293 aa)
DNF11_2124Afadin-and alpha-actinin-Binding protein. (318 aa)
arc1Actin-related protein 2/3 complex subunit 1. (429 aa)
CBK1Serine/threonine-protein kinase CBK1. (508 aa)
TUB4Tubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. (453 aa)
CDC11Cell division control protein 11; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (343 aa)
kif11_2Kinesin-related protein 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1041 aa)
MYO1Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1252 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (392 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
crn1Coronin; Belongs to the WD repeat coronin family. (634 aa)
NPL4Nuclear protein localization protein 4. (599 aa)
DNF11_2366ENTH domain-containing protein. (401 aa)
ask1DASH complex subunit ask1. (395 aa)
DNF11_0627Actin-2; Belongs to the actin family. (885 aa)
nudADynein heavy chain, cytoplasmic. (2907 aa)
rhoAGTP-binding protein rhoA. (205 aa)
WRAP73WD repeat-containing protein WRAP73. (528 aa)
sla1Actin cytoskeleton-regulatory complex protein sla1. (1001 aa)
end4Endocytosis protein end4. (1489 aa)
tea4Tip elongation aberrant protein Tea4. (951 aa)
COF1Cofilin; Belongs to the actin-binding proteins ADF family. (139 aa)
Cdc42bpbSerine/threonine-protein kinase MRCK beta. (1029 aa)
rga1Rho-type GTPase-activating protein 1. (1017 aa)
rho1GTP-binding protein rho1. (205 aa)
DNF11_2973Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
DNF11_3033Uncharacterized protein. (1002 aa)
ppk30Serine/threonine-protein kinase ppk30. (762 aa)
plo1Serine/threonine-protein kinase. (810 aa)
scd1Rho guanine nucleotide exchange factor scd1. (866 aa)
DYNC1H1Cytoplasmic dynein 1 heavy chain 1. (1486 aa)
CDC10Cell division control protein 10; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (324 aa)
MPS1Serine/threonine-protein kinase MPS1. (562 aa)
alp6Spindle pole body component. (689 aa)
wat1WD repeat-containing protein wat1. (363 aa)
alp4Spindle pole body component alp4. (1560 aa)
ent1Epsin-1. (428 aa)
DNF11_3605SH3 domain-containing protein. (828 aa)
SAC6Fimbrin. (615 aa)
cdc37Hsp90 co-chaperone Cdc37. (495 aa)
TUB1Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
ZNF207Zinc finger protein 207. (228 aa)
tbceTubulin-specific chaperone E. (457 aa)
DNF11_1887Uncharacterized protein. (515 aa)
ark1Serine/threonine-protein kinase ark1; Belongs to the protein kinase superfamily. (432 aa)
arc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (177 aa)
CLIP1CAP-Gly domain-containing linker protein 1. (619 aa)
RRD2Serine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (426 aa)
nudENuclear distribution protein nudE. (400 aa)
Arpc4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
vps1Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (681 aa)
RVS167Reduced viability upon starvation protein 167. (381 aa)
kif11_1Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (870 aa)
SIW14Tyrosine-protein phosphatase SIW14. (287 aa)
DNF11_0390Uncharacterized protein. (428 aa)
rid1GTPase-binding protein rid1. (393 aa)
BIM1Protein BIM1. (661 aa)
DNF11_0781SH3 domain-containing protein. (462 aa)
DCTN1Dynactin subunit 1. (1019 aa)
TUB-BTubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (456 aa)
bimCKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (797 aa)
DNF11_0108Uncharacterized protein. (588 aa)
DNF11_0272Uncharacterized protein. (1113 aa)
STRIP1Striatin-interacting protein 1. (1031 aa)
DNF11_1101Uncharacterized protein. (553 aa)
cdc31Cell division control protein 31. (184 aa)
DNF11_0866Actin. (360 aa)
TPM2Tropomyosin-2. (161 aa)
CDC14Tyrosine-protein phosphatase CDC14. (617 aa)
klp6Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1082 aa)
TUB-1ATubulin alpha chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (451 aa)
ase1Anaphase spindle elongation protein 1. (666 aa)
Dync1li2Cytoplasmic dynein 1 light intermediate chain 2. (437 aa)
arc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (309 aa)
DNF11_1132WH2 domain-containing protein. (355 aa)
CDC48Cell division control protein 48; Belongs to the AAA ATPase family. (830 aa)
imp2Septation protein imp2. (723 aa)
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
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