STRINGSTRING
BUD6 BUD6 dip1 dip1 act2 act2 CAPZB CAPZB Arpc5 Arpc5 CLTC CLTC crn1 crn1 DNF11_2366 DNF11_2366 rhoA rhoA myo2 myo2 BNI1 BNI1 ARHGDIA ARHGDIA cdc4 cdc4 sla1 sla1 end4 end4 tea4 tea4 COF1 COF1 Cdc42bpb Cdc42bpb rga1 rga1 rho1 rho1 DNF11_2973 DNF11_2973 DNF11_3033 DNF11_3033 ppk30 ppk30 wat1 wat1 ent1 ent1 DNF11_3605 DNF11_3605 Pxn Pxn CDC42 CDC42 arc3 arc3 SAC6 SAC6 hob3 hob3 actr2 actr2 Arpc4 Arpc4 vps1 vps1 RVS167 RVS167 SIW14 SIW14 rid1 rid1 DNF11_0781 DNF11_0781 arc1 arc1 DNF11_0108 DNF11_0108 arc2 arc2 DNF11_1132 DNF11_1132 imp2 imp2 DNF11_2000 DNF11_2000 DNF11_0272 DNF11_0272 TPM2 TPM2 CDC14 CDC14 CBK1 CBK1 MYO1 MYO1 cap1 cap1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BUD6Bud site selection protein 6. (841 aa)
dip1Protein dip1. (606 aa)
act2Actin-related protein 3; Belongs to the actin family. (436 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (284 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (156 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1675 aa)
crn1Coronin; Belongs to the WD repeat coronin family. (634 aa)
DNF11_2366ENTH domain-containing protein. (401 aa)
rhoAGTP-binding protein rhoA. (205 aa)
myo2Myosin type-2 heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1326 aa)
BNI1Protein BNI1. (1640 aa)
ARHGDIARho GDP-dissociation inhibitor 1. (219 aa)
cdc4Myosin regulatory light chain cdc4. (140 aa)
sla1Actin cytoskeleton-regulatory complex protein sla1. (1001 aa)
end4Endocytosis protein end4. (1489 aa)
tea4Tip elongation aberrant protein Tea4. (951 aa)
COF1Cofilin; Belongs to the actin-binding proteins ADF family. (139 aa)
Cdc42bpbSerine/threonine-protein kinase MRCK beta. (1029 aa)
rga1Rho-type GTPase-activating protein 1. (1017 aa)
rho1GTP-binding protein rho1. (205 aa)
DNF11_2973Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
DNF11_3033Uncharacterized protein. (1002 aa)
ppk30Serine/threonine-protein kinase ppk30. (762 aa)
wat1WD repeat-containing protein wat1. (363 aa)
ent1Epsin-1. (428 aa)
DNF11_3605SH3 domain-containing protein. (828 aa)
PxnPaxillin. (350 aa)
CDC42Cell division control protein 42. (191 aa)
arc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (177 aa)
SAC6Fimbrin. (615 aa)
hob3Protein hob3. (262 aa)
actr2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (392 aa)
Arpc4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
vps1Vacuolar protein sorting-associated protein 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (681 aa)
RVS167Reduced viability upon starvation protein 167. (381 aa)
SIW14Tyrosine-protein phosphatase SIW14. (287 aa)
rid1GTPase-binding protein rid1. (393 aa)
DNF11_0781SH3 domain-containing protein. (462 aa)
arc1Actin-related protein 2/3 complex subunit 1. (429 aa)
DNF11_0108Uncharacterized protein. (588 aa)
arc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (309 aa)
DNF11_1132WH2 domain-containing protein. (355 aa)
imp2Septation protein imp2. (723 aa)
DNF11_2000Ysc84 domain-containing protein. (293 aa)
DNF11_0272Uncharacterized protein. (1113 aa)
TPM2Tropomyosin-2. (161 aa)
CDC14Tyrosine-protein phosphatase CDC14. (617 aa)
CBK1Serine/threonine-protein kinase CBK1. (508 aa)
MYO1Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1252 aa)
cap1Adenylyl cyclase-associated protein; Belongs to the CAP family. (491 aa)
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.