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mot1 mot1 DNF11_3820 DNF11_3820 DNF11_2973 DNF11_2973 Pros45 Pros45 cap-1 cap-1 pkcA pkcA rhoA rhoA DNF11_2430 DNF11_2430 pab1 pab1 DNF11_1672 DNF11_1672 PSMC4 PSMC4 SAR1 SAR1 MYO1 MYO1 SNX4 SNX4 sed5 sed5 arc1 arc1 Pxn Pxn CDC42 CDC42 arc3 arc3 DNF11_3864 DNF11_3864 rav1 rav1 dma1 dma1 rpt4 rpt4 ncb2 ncb2 plo1 plo1 pkaR pkaR DNF11_3033 DNF11_3033 cap1 cap1 BUD6 BUD6 DBNL DBNL CAPZB CAPZB Arpc5 Arpc5 crk1 crk1 gap1 gap1 POB3 POB3 SED4 SED4 DNF11_1132 DNF11_1132 DNF11_1843 DNF11_1843 arc2 arc2 CTI6 CTI6 CDC14 CDC14 clr3 clr3 cpc-2 cpc-2 rgf3 rgf3 DNF11_0108 DNF11_0108 DNF11_0189 DNF11_0189 NPRL2 NPRL2 PPP2R5D PPP2R5D DNF11_0551 DNF11_0551 tbp1_1 tbp1_1 Sacs Sacs Arpc4 Arpc4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mot1Putative helicase mot1. (1772 aa)
DNF11_3820SPT2 chromatin protein. (286 aa)
DNF11_2973Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
Pros4526S protease regulatory subunit 8; Belongs to the AAA ATPase family. (416 aa)
cap-1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (358 aa)
pkcAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1264 aa)
rhoAGTP-binding protein rhoA. (205 aa)
DNF11_2430RRM domain-containing protein. (547 aa)
pab1Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (493 aa)
DNF11_1672Uncharacterized protein. (257 aa)
PSMC426S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (409 aa)
SAR1Small COPII coat GTPase SAR1; Belongs to the small GTPase superfamily. SAR1 family. (189 aa)
MYO1Myosin-1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1252 aa)
SNX4Sorting nexin-4. (492 aa)
sed5Integral membrane protein sed5; Belongs to the syntaxin family. (336 aa)
arc1Actin-related protein 2/3 complex subunit 1. (429 aa)
PxnPaxillin. (350 aa)
CDC42Cell division control protein 42. (191 aa)
arc3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (177 aa)
DNF11_3864Uncharacterized protein. (222 aa)
rav1Regulator of V-ATPase in vacuolar membrane protein 1. (1268 aa)
dma1Putative E3 ubiquitin-protein ligase dma1. (334 aa)
rpt4Putative 26S protease subunit rpt4; Belongs to the AAA ATPase family. (390 aa)
ncb2Negative cofactor 2 complex subunit beta. (146 aa)
plo1Serine/threonine-protein kinase. (810 aa)
pkaRcAMP-dependent protein kinase regulatory subunit. (313 aa)
DNF11_3033Uncharacterized protein. (1002 aa)
cap1Adenylyl cyclase-associated protein; Belongs to the CAP family. (491 aa)
BUD6Bud site selection protein 6. (841 aa)
DBNLDrebrin-like protein. (607 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (284 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (156 aa)
crk1Serine/threonine-protein kinase crk1; Belongs to the protein kinase superfamily. (369 aa)
gap1GTPase-activating protein. (747 aa)
POB3FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (574 aa)
SED4Guanine nucleotide-exchange factor SED4. (378 aa)
DNF11_1132WH2 domain-containing protein. (355 aa)
DNF11_1843Uncharacterized protein. (258 aa)
arc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (309 aa)
CTI6Histone deacetylase complex subunit CTI6. (492 aa)
CDC14Tyrosine-protein phosphatase CDC14. (617 aa)
clr3Histone deacetylase clr3. (642 aa)
cpc-2Guanine nucleotide-binding protein subunit beta-like protein. (324 aa)
rgf3Rho1 guanine nucleotide exchange factor 3. (1084 aa)
DNF11_0108Uncharacterized protein. (588 aa)
DNF11_0189Uncharacterized protein. (559 aa)
NPRL2Nitrogen permease regulator 2-like protein. (696 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (751 aa)
DNF11_0551DNA replication and checkpoint protein. (431 aa)
tbp1_126S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (427 aa)
SacsSacsin. (1690 aa)
Arpc4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
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