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DNF11_3033 DNF11_3033 cnp3 cnp3 DNF11_3767 DNF11_3767 DNF11_3747 DNF11_3747 PSMD10 PSMD10 TIF6 TIF6 ERB1 ERB1 dip1 dip1 Actr10 Actr10 DNF11_3779 DNF11_3779 DBNL DBNL CAPZB CAPZB ria1 ria1 NDUFAF2 NDUFAF2 SRP68 SRP68 Arpc5 Arpc5 PAC1_2 PAC1_2 Srpr Srpr tor2 tor2 tif211 tif211 myo2 myo2 POB3 POB3 hhoA hhoA HET-E1_2 HET-E1_2 Srprb Srprb tfg1 tfg1 HIR1 HIR1 RBM39 RBM39 FYV4 FYV4 SAC6 SAC6 zuo1 zuo1 GMFB GMFB rng2 rng2 DNF11_1357 DNF11_1357 Rpn11 Rpn11 DNF11_2522 DNF11_2522 DNF11_3233 DNF11_3233 DNF11_3281 DNF11_3281 gcn1 gcn1 SPT6 SPT6 DNF11_3191 DNF11_3191 letm1 letm1 slp1_1 slp1_1 DNF11_2993 DNF11_2993 rpa3 rpa3 FIL1 FIL1 cap-1 cap-1 COF1 COF1 Ndufa4l2 Ndufa4l2 end4 end4 DNF11_2795 DNF11_2795 ECD ECD crn1 crn1 ubp6 ubp6 DNF11_2425 DNF11_2425 MAD1 MAD1 frr frr DNF11_1629 DNF11_1629 PRP5 PRP5 vps28 vps28 arc1 arc1 DNF11_2000 DNF11_2000 nuf2 nuf2 nuo-40 nuo-40 DNF11_0829 DNF11_0829 srw1 srw1 DNF11_0899 DNF11_0899 YTM1 YTM1 SPT16 SPT16 arc2 arc2 IMA1 IMA1 psme4 psme4 NOP7 NOP7 DNF11_1132 DNF11_1132 DNF11_0011 DNF11_0011 rhp23 rhp23 sec-61 sec-61 Arpc4 Arpc4 sce3 sce3 Sacs Sacs NMD3 NMD3 Dynll1 Dynll1 ISW2 ISW2 mad2 mad2 ANB1 ANB1 GUF1 GUF1 DNF11_0681 DNF11_0681 DNF11_0781 DNF11_0781 Gorasp2 Gorasp2 cbp3 cbp3 DNF11_0008 DNF11_0008 DNF11_0875 DNF11_0875 DNF11_0108 DNF11_0108 strap strap DNF11_1073 DNF11_1073 TPM2 TPM2 cpc-2 cpc-2 TSR2 TSR2 ARP6 ARP6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DNF11_3033Uncharacterized protein. (1002 aa)
cnp3Centromere protein 3. (691 aa)
DNF11_3767Putative AAA domain-containing protein C16E9.10c. (706 aa)
DNF11_3747Uncharacterized protein. (200 aa)
PSMD1026S proteasome non-ATPase regulatory subunit 10. (247 aa)
TIF6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (245 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (823 aa)
dip1Protein dip1. (606 aa)
Actr10Actin-related protein 10; Belongs to the actin family. (329 aa)
DNF11_3779NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (138 aa)
DBNLDrebrin-like protein. (607 aa)
CAPZBF-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (284 aa)
ria1Ribosome assembly protein 1. (1013 aa)
NDUFAF2Mimitin, mitochondrial. (175 aa)
SRP68Signal recognition particle subunit SRP68. (719 aa)
Arpc5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (156 aa)
PAC1_2Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (428 aa)
SrprSignal recognition particle receptor subunit alpha. (640 aa)
tor2Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2352 aa)
tif211Eukaryotic translation initiation factor 2 subunit alpha. (298 aa)
myo2Myosin type-2 heavy chain 1; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1326 aa)
POB3FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (574 aa)
hhoAHistone H1. (201 aa)
HET-E1_2Vegetative incompatibility protein HET-E-1. (369 aa)
SrprbSignal recognition particle receptor subunit beta. (357 aa)
tfg1Transcription initiation factor IIF subunit alpha. (640 aa)
HIR1Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (794 aa)
RBM39RNA-binding protein 39. (428 aa)
FYV4Protein FYV4, mitochondrial. (140 aa)
SAC6Fimbrin. (615 aa)
zuo1Zuotin. (448 aa)
GMFBGlia maturation factor beta. (138 aa)
rng2Ras GTPase-activating-like protein rng2. (1582 aa)
DNF11_1357Uncharacterized protein. (521 aa)
Rpn1126S proteasome non-ATPase regulatory subunit 14. (308 aa)
DNF11_2522Mago binding protein. (196 aa)
DNF11_3233WLM domain-containing protein. (320 aa)
DNF11_3281LETM1-like protein. (318 aa)
gcn1Translational activator gcn1. (2582 aa)
SPT6Transcription elongation factor SPT6. (1497 aa)
DNF11_3191Uncharacterized protein. (319 aa)
letm1LETM1 and EF-hand domain-containing protein 1, mitochondrial. (624 aa)
slp1_1WD repeat-containing protein slp1. (568 aa)
DNF11_2993Eukaryotic translation initiation factor 2A; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl- tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. (581 aa)
rpa360S acidic ribosomal protein P1-alpha 3; Belongs to the eukaryotic ribosomal protein P1/P2 family. (110 aa)
FIL1Guanine nucleotide-binding protein alpha-3 subunit. (359 aa)
cap-1F-actin-capping protein subunit alpha; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. (358 aa)
COF1Cofilin; Belongs to the actin-binding proteins ADF family. (139 aa)
Ndufa4l2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2. (86 aa)
end4Endocytosis protein end4. (1489 aa)
DNF11_2795UBX domain protein. (231 aa)
ECDProtein SGT1. (725 aa)
crn1Coronin; Belongs to the WD repeat coronin family. (634 aa)
ubp6Ubiquitin carboxyl-terminal hydrolase. (505 aa)
DNF11_2425Phosducin-like protein C2A9.09. (215 aa)
MAD1Spindle assembly checkpoint component MAD1. (813 aa)
frrRibosome-recycling factor. (190 aa)
DNF11_1629E3 ubiquitin-protein ligase listerin. (1633 aa)
PRP5Pre-mRNA-processing ATP-dependent RNA helicase PRP5. (869 aa)
vps28Vacuolar protein sorting-associated protein 28; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (214 aa)
arc1Actin-related protein 2/3 complex subunit 1. (429 aa)
DNF11_2000Ysc84 domain-containing protein. (293 aa)
nuf2Kinetochore protein nuf2. (443 aa)
nuo-40NADH-ubiquinone oxidoreductase 40 kDa subunit, mitochondrial. (384 aa)
DNF11_0829LIM domain and RING finger protein.01. (617 aa)
srw1WD repeat-containing protein srw1. (565 aa)
DNF11_0899Epimerase domain-containing protein. (305 aa)
YTM1Ribosome biogenesis protein YTM1. (471 aa)
SPT16FACT complex subunit SPT16. (584 aa)
arc2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (309 aa)
IMA1Integral inner nuclear membrane protein ima1. (394 aa)
psme4Proteasome activator complex subunit 4. (1867 aa)
NOP7Pescadillo homolog; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (648 aa)
DNF11_1132WH2 domain-containing protein. (355 aa)
DNF11_0011OBG-type G domain-containing protein. (697 aa)
rhp23UV excision repair protein rhp23. (376 aa)
sec-61Protein transport protein SEC61 subunit alpha. (478 aa)
Arpc4Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (168 aa)
sce3Putative RNA-binding protein sce3. (383 aa)
SacsSacsin. (1690 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (555 aa)
Dynll1Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (103 aa)
ISW2ISWI chromatin-remodeling complex ATPase ISW2. (1002 aa)
mad2Mitotic spindle checkpoint component mad2. (223 aa)
ANB1Eukaryotic translation initiation factor 5A. (160 aa)
GUF1Translation factor GUF1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. (587 aa)
DNF11_0681FRG1-like family protein. (250 aa)
DNF11_0781SH3 domain-containing protein. (462 aa)
Gorasp2Golgi reassembly-stacking protein 2. (289 aa)
cbp3CBP3-like protein. (281 aa)
DNF11_0008Uncharacterized protein. (532 aa)
DNF11_0875Mitochondrial acidic protein mam33. (269 aa)
DNF11_0108Uncharacterized protein. (588 aa)
strapSerine-threonine kinase receptor-associated protein. (614 aa)
DNF11_1073Uncharacterized protein. (762 aa)
TPM2Tropomyosin-2. (161 aa)
cpc-2Guanine nucleotide-binding protein subunit beta-like protein. (324 aa)
TSR2Pre-rRNA-processing protein TSR2. (197 aa)
ARP6Actin-like protein ARP6; Belongs to the actin family. (482 aa)
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
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