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RAD50 RAD50 NPL4 NPL4 vma3 vma3 DNF11_2604 DNF11_2604 vma-7 vma-7 hap2 hap2 mrp10 mrp10 DNF11_1922 DNF11_1922 DNF11_2705 DNF11_2705 SCO1 SCO1 STI1 STI1 Ndufa4l2 Ndufa4l2 MKP2 MKP2 cyc1 cyc1 DNF11_3001 DNF11_3001 hsf1 hsf1 DNF11_0887 DNF11_0887 UFD1 UFD1 DNF11_2179 DNF11_2179 VMA2 VMA2 L7rn6 L7rn6 DNF11_3083 DNF11_3083 DNF11_3184 DNF11_3184 DNF11_3215 DNF11_3215 rhb1 rhb1 gcn1 gcn1 Dmn Dmn DNF11_1217 DNF11_1217 DNF11_3294 DNF11_3294 DNF11_3146 DNF11_3146 ASF1 ASF1 DNF11_2488 DNF11_2488 SSZ1 SSZ1 wat1 wat1 wis1 wis1 ESA1 ESA1 zuo1 zuo1 DNF11_2788 DNF11_2788 HAP3 HAP3 sod2 sod2 mlkA mlkA DNF11_3734 DNF11_3734 COX13 COX13 DNF11_1807 DNF11_1807 SSB SSB vma-8 vma-8 PRMT13 PRMT13 HIR1 HIR1 atp6v1c1 atp6v1c1 vma1 vma1 Srprb Srprb nup146 nup146 cox2 cox2 skh1 skh1 cox1 cox1 chl1 chl1 tor2 tor2 Srpr Srpr vph-1 vph-1 DNF11_3638 DNF11_3638 HSP81-3 HSP81-3 Dctn4 Dctn4 SIN3 SIN3 NUP205 NUP205 dhkJ dhkJ DNF11_3979 DNF11_3979 hyou1 hyou1 ssb1 ssb1 afg2 afg2 DNF11_3807 DNF11_3807 wos2 wos2 hrf1 hrf1 cox3 cox3 FMP21 FMP21 DNF11_0200 DNF11_0200 scn1 scn1 DNF11_0086 DNF11_0086 FAO2 FAO2 CPK1 CPK1 NPR3 NPR3 DNF11_0551 DNF11_0551 DNF11_0603 DNF11_0603 CCP2 CCP2 NPRL2 NPRL2 vha-10 vha-10 DNF11_0396 DNF11_0396 DNF11_0674 DNF11_0674 GPX2 GPX2 cmkA cmkA SHY1 SHY1 NSP1_1 NSP1_1 SWR1 SWR1 gcn2 gcn2 tetA tetA DCTN1 DCTN1 COX11 COX11 Sod2b Sod2b VhaSFD VhaSFD tbl1xr1-a tbl1xr1-a ppk4 ppk4 cya-4 cya-4 VMA4 VMA4 ssn6 ssn6 FUZ7 FUZ7 samB samB IML1 IML1 STE11 STE11 TEF1 TEF1 DNF11_1070 DNF11_1070 DNF11_1191 DNF11_1191 vma16 vma16 gtr2 gtr2 COX6 COX6 DNF11_0996 DNF11_0996 clr3 clr3 NFYC2 NFYC2 mcs4 mcs4 gacS gacS DNF11_0752 DNF11_0752 RPL40 RPL40 new16 new16 Nup160 Nup160 Dync1li2 Dync1li2 rbx-1 rbx-1 DNF11_1733 DNF11_1733 mas5 mas5 CCP1 CCP1 DNF11_0982 DNF11_0982 NSP1_2 NSP1_2 RPS27A RPS27A CLYBL CLYBL UMS2 UMS2 Hm13 Hm13 Rraga Rraga CDC48 CDC48 DNF11_1895 DNF11_1895 cox-4 cox-4 DNF11_1279 DNF11_1279 MRE11 MRE11 HSF2 HSF2 hsp-88 hsp-88 HTB1 HTB1 cmk1 cmk1 vma6 vma6 mip1 mip1 spm1 spm1 srk1 srk1 GLR1 GLR1 DNF11_2086 DNF11_2086 DNF11_1408 DNF11_1408 MBTPS2 MBTPS2 gsk3 gsk3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD50DNA repair protein RAD50. (1050 aa)
NPL4Nuclear protein localization protein 4. (599 aa)
vma3V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (163 aa)
DNF11_2604Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the amidase family. GatA subfamily. (440 aa)
vma-7V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (120 aa)
hap2Transcriptional activator hap2. (544 aa)
mrp1037S ribosomal protein mrp10, mitochondrial. (79 aa)
DNF11_1922Anaphase-promoting complex subunit 5. (657 aa)
DNF11_2705Uncharacterized protein. (1873 aa)
SCO1Protein SCO1, mitochondrial. (312 aa)
STI1Heat shock protein STI1. (584 aa)
Ndufa4l2NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2. (86 aa)
MKP2Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (401 aa)
cyc1Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (100 aa)
DNF11_3001Putative RWD, RING finger and WD repeat-containing protein C11E3.05. (694 aa)
hsf1Heat shock factor protein. (623 aa)
DNF11_0887Thioredoxin-like_fold domain-containing protein. (235 aa)
UFD1Ubiquitin fusion degradation protein 1. (384 aa)
DNF11_2179Uncharacterized protein. (366 aa)
VMA2Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (510 aa)
L7rn6Protein Hikeshi. (188 aa)
DNF11_3083Antibiotic biosynthesis monooxygenase. (105 aa)
DNF11_318437S ribosomal protein S26A, mitochondrial. (277 aa)
DNF11_3215Flavin_Reduct domain-containing protein. (216 aa)
rhb1GTP-binding protein rhb1. (192 aa)
gcn1Translational activator gcn1. (2582 aa)
DmnPutative dynactin subunit 2. (316 aa)
DNF11_1217NAD-dependent protein deacetylase hst1. (463 aa)
DNF11_3294Thioredoxin Y, chloroplastic. (145 aa)
DNF11_3146J domain-containing protein. (422 aa)
ASF1Histone chaperone ASF1. (204 aa)
DNF11_2488Chaperone protein DnaJ. (500 aa)
SSZ1Ribosome-associated complex subunit SSZ1; Belongs to the heat shock protein 70 family. (587 aa)
wat1WD repeat-containing protein wat1. (363 aa)
wis1Protein kinase wis1. (479 aa)
ESA1Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (466 aa)
zuo1Zuotin. (448 aa)
DNF11_2788Heat shock factor binding protein 1. (69 aa)
HAP3Transcriptional activator HAP3. (233 aa)
sod2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (202 aa)
mlkAMyosin light chain kinase A. (927 aa)
DNF11_3734Uncharacterized protein. (300 aa)
COX13Cytochrome c oxidase subunit 6A, mitochondrial; Belongs to the cytochrome c oxidase subunit 6A family. (134 aa)
DNF11_1807Thioredoxin; Belongs to the thioredoxin family. (108 aa)
SSBHeat shock protein SSB; Belongs to the heat shock protein 70 family. (619 aa)
vma-8V-type proton ATPase subunit D. (264 aa)
PRMT13Putative histone-arginine methyltransferase 1.3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (401 aa)
HIR1Protein HIR; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (794 aa)
atp6v1c1V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (396 aa)
vma1V-type proton ATPase catalytic subunit A. (618 aa)
SrprbSignal recognition particle receptor subunit beta. (357 aa)
nup146Nucleoporin nup146. (1686 aa)
cox2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (263 aa)
skh1MAP kinase kinase skh1/pek1. (428 aa)
cox1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (528 aa)
chl1ATP-dependent RNA helicase chl1. (786 aa)
tor2Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2352 aa)
SrprSignal recognition particle receptor subunit alpha. (640 aa)
vph-1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (843 aa)
DNF11_3638Uncharacterized protein. (233 aa)
HSP81-3Heat shock protein 81-3. (698 aa)
Dctn4Dynactin subunit 4. (290 aa)
SIN3Transcriptional regulatory protein SIN3. (1227 aa)
NUP205Nuclear pore complex protein Nup205. (1877 aa)
dhkJHybrid signal transduction histidine kinase J. (1296 aa)
DNF11_3979Chaperone protein DnaJ. (384 aa)
hyou1Hypoxia up-regulated protein 1. (880 aa)
ssb1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (621 aa)
afg2ATPase family gene 2 protein. (729 aa)
DNF11_3807Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (172 aa)
wos2Protein wos2. (198 aa)
hrf1Protein transport protein yif1. (372 aa)
cox3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (287 aa)
FMP21Protein FMP21, mitochondrial. (117 aa)
DNF11_0200Chaperone protein DnaJ. (408 aa)
scn1Cut9-interacting protein scn1. (301 aa)
DNF11_0086Hamartin protein. (764 aa)
FAO2Long-chain-alcohol oxidase FAO2. (1031 aa)
CPK1Mitogen-activated protein kinase. (296 aa)
NPR3Nitrogen permease regulator 3. (732 aa)
DNF11_0551DNA replication and checkpoint protein. (431 aa)
DNF11_0603Transcription initiation factor TFIID component TAF4 family protein. (488 aa)
CCP2Peroxidase; Belongs to the peroxidase family. (303 aa)
NPRL2Nitrogen permease regulator 2-like protein. (696 aa)
vha-10V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (120 aa)
DNF11_0396J domain-containing protein. (327 aa)
DNF11_0674Deoxyribonuclease Tat-D. (326 aa)
GPX2Glutathione peroxidase; Belongs to the glutathione peroxidase family. (159 aa)
cmkACalcium/calmodulin-dependent protein kinase; Belongs to the protein kinase superfamily. (384 aa)
SHY1SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (277 aa)
NSP1_1Nucleoporin NSP1. (1100 aa)
SWR1Helicase SWR1. (1396 aa)
gcn2Serine/threonine-protein kinase gcn2. (1650 aa)
tetATetracycline resistance protein, class C. (640 aa)
DCTN1Dynactin subunit 1. (1019 aa)
COX11Cytochrome c oxidase assembly protein COX11, mitochondrial. (268 aa)
Sod2bSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (203 aa)
VhaSFDV-type proton ATPase subunit H. (481 aa)
tbl1xr1-aF-box-like/WD repeat-containing protein TBL1XR1-A. (584 aa)
ppk4Serine/threonine-protein kinase ppk4. (977 aa)
cya-4Cytochrome c oxidase polypeptide 5, mitochondrial. (184 aa)
VMA4V-type proton ATPase subunit E. (226 aa)
ssn6General transcriptional corepressor ssn6. (810 aa)
FUZ7Dual specificity protein kinase FUZ7. (626 aa)
samBMYND-type zinc finger protein samB. (681 aa)
IML1Vacuolar membrane-associated protein IML1. (1448 aa)
STE11Serine/threonine-protein kinase STE11. (875 aa)
TEF1Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (460 aa)
DNF11_1070Molecular chaperone DnaK; Belongs to the heat shock protein 70 family. (673 aa)
DNF11_1191Cytochrome c oxidase subunit VIIc. (74 aa)
vma16Putative V-type proton ATPase 20 kDa proteolipidsubunit; Belongs to the V-ATPase proteolipid subunit family. (197 aa)
gtr2GTP-binding protein gtr2. (372 aa)
COX6Cytochrome c oxidase subunit 6, mitochondrial. (140 aa)
DNF11_099660Kd inner membrane protein. (295 aa)
clr3Histone deacetylase clr3. (642 aa)
NFYC2Nuclear transcription factor Y subunit C-2. (357 aa)
mcs4Response regulator mcs4. (923 aa)
gacSSensor protein GacS. (1040 aa)
DNF11_0752Chaperone protein DnaJ. (382 aa)
RPL4060S ribosomal protein L40. (152 aa)
new16Cytochrome c oxidase subunit 6B-like protein new16. (116 aa)
Nup160Nuclear pore complex protein Nup160. (1296 aa)
Dync1li2Cytoplasmic dynein 1 light intermediate chain 2. (437 aa)
rbx-1RING-box protein 1. (105 aa)
DNF11_1733Mitoc_mL59 domain-containing protein. (205 aa)
mas5Mitochondrial protein import protein mas5. (427 aa)
CCP1Peroxidase; Belongs to the peroxidase family. (367 aa)
DNF11_0982Heat shock 70 kDa protein; Belongs to the heat shock protein 70 family. (659 aa)
NSP1_2Nucleoporin NSP1. (829 aa)
RPS27A40S ribosomal protein S27a. (158 aa)
CLYBLCitrate lyase subunit beta-like protein, mitochondrial. (276 aa)
UMS2Heat shock 70 kDa protein 2; Belongs to the heat shock protein 70 family. (638 aa)
Hm13Minor histocompatibility antigen H13. (389 aa)
RragaRas-related GTP-binding protein A. (382 aa)
CDC48Cell division control protein 48; Belongs to the AAA ATPase family. (830 aa)
DNF11_1895Uncharacterized protein. (519 aa)
cox-4Cytochrome c oxidase subunit 4, mitochondrial. (153 aa)
DNF11_1279Uncharacterized protein. (486 aa)
MRE11Double-strand break repair protein MRE11; Belongs to the MRE11/RAD32 family. (540 aa)
HSF2Heat shock factor protein 2. (540 aa)
hsp-88Heat shock protein Hsp88. (778 aa)
HTB1Histone H2B; Belongs to the histone H2B family. (141 aa)
cmk1Calcium/calmodulin-dependent protein kinase typeI; Belongs to the protein kinase superfamily. (358 aa)
vma6V-type proton ATPase subunit d. (311 aa)
mip1WD repeat-containing protein mip1. (1525 aa)
spm1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (536 aa)
srk1Serine/threonine-protein kinase srk1. (568 aa)
GLR1Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (481 aa)
DNF11_2086FCP1 homology domain-containing protein. (450 aa)
DNF11_1408BAG domain protein. (253 aa)
MBTPS2Membrane-bound transcription factor site-2 protease. (472 aa)
gsk3Protein kinase gsk3. (401 aa)
Your Current Organism:
Malassezia restricta
NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877
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