50 items (Malassezia restricta) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	DNF11_1732	Uncharacterized protein. (321 aa)
	CPR	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (713 aa)
	DNF11_0086	Hamartin protein. (764 aa)
	CPK1	Mitogen-activated protein kinase. (296 aa)
	vha-10	V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (120 aa)
	DNF11_0022	Arf-GAP domain-containing protein. (342 aa)
	Ppp4r1	Serine/threonine-protein phosphatase 4 regulatory subunit 1. (1057 aa)
	ste16	Protein ste16. (1205 aa)
	VhaSFD	V-type proton ATPase subunit H. (481 aa)
	VMA4	V-type proton ATPase subunit E. (226 aa)
	DNF11_0991	WD_REPEATS_REGION domain-containing protein. (446 aa)
	MCM1	Pheromone receptor transcription factor. (464 aa)
	SLT2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (550 aa)
	sck1	Non-specific serine/threonine protein kinase. (629 aa)
	vma16	Putative V-type proton ATPase 20 kDa proteolipidsubunit; Belongs to the V-ATPase proteolipid subunit family. (197 aa)
	RPL40	60S ribosomal protein L40. (152 aa)
	DNF11_1336	HbrB-like protein. (655 aa)
	CHK1	Serine/threonine-protein kinase CHK1; Belongs to the protein kinase superfamily. (487 aa)
	pph-1	Serine/threonine-protein phosphatase. (306 aa)
	DNF11_1584	Putative ADP-ribosylation factor-binding proteinC25H2.16c. (431 aa)
	paa1	Protein phosphatase PP2A regulatory subunit A. (588 aa)
	RPS27A	40S ribosomal protein S27a. (158 aa)
	SHO1	High osmolarity signaling protein SHO1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (379 aa)
	pep12	Syntaxin pep12; Belongs to the syntaxin family. (293 aa)
	vma6	V-type proton ATPase subunit d. (311 aa)
	spm1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (536 aa)
	ksg1	Serine/threonine-protein kinase ksg1. (968 aa)
	gad8	Non-specific serine/threonine protein kinase. (538 aa)
	ssh4	Protein ssh4. (477 aa)
	EMI1	Early meiotic induction protein 1. (155 aa)
	ehs1	Calcium influx-promoting protein ehs1. (673 aa)
	csh3	Protein csh3. (224 aa)
	vma3	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (163 aa)
	vma-7	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (120 aa)
	pkcA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1264 aa)
	MKP2	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (401 aa)
	VMA2	Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (510 aa)
	DNF11_3215	Flavin_Reduct domain-containing protein. (216 aa)
	HOG1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (386 aa)
	wat1	WD repeat-containing protein wat1. (363 aa)
	VPS27	Vacuolar protein sorting-associated protein 27. (428 aa)
	vma-8	V-type proton ATPase subunit D. (264 aa)
	atp6v1c1	V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (396 aa)
	Dusp12	Dual specificity protein phosphatase 12. (325 aa)
	vma1	V-type proton ATPase catalytic subunit A. (618 aa)
	sin1	Stress-activated map kinase-interacting protein 1. (698 aa)
	Pxn	Paxillin. (350 aa)
	tor2	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2352 aa)
	vph-1	V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (843 aa)
	HSP81-3	Heat shock protein 81-3. (698 aa)

Your Current Organism:

Malassezia restricta

NCBI taxonomy Id: 425264
Other names: M. restricta CBS 7877, Malassezia restricta CBS 7877

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHK1	pph-1	A0A3G2S3E5	A0A3G2S3F8	Serine/threonine-protein kinase CHK1; Belongs to the protein kinase superfamily.	Serine/threonine-protein phosphatase.	0.827
CPK1	Dusp12	A0A3G2S063	A0A3G2SA15	Mitogen-activated protein kinase.	Dual specificity protein phosphatase 12.	0.602
CPK1	EMI1	A0A3G2S063	A0A3G2S5T1	Mitogen-activated protein kinase.	Early meiotic induction protein 1.	0.499
CPK1	HOG1	A0A3G2S063	A0A3G2S844	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.419
CPK1	MKP2	A0A3G2S063	A0A3G2S6Y1	Mitogen-activated protein kinase.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.902
CPK1	ehs1	A0A3G2S063	A0A3G2S5W8	Mitogen-activated protein kinase.	Calcium influx-promoting protein ehs1.	0.405
CPK1	gad8	A0A3G2S063	A0A3G2S5G5	Mitogen-activated protein kinase.	Non-specific serine/threonine protein kinase.	0.473
CPK1	ksg1	A0A3G2S063	A0A3G2S587	Mitogen-activated protein kinase.	Serine/threonine-protein kinase ksg1.	0.401
CPK1	pph-1	A0A3G2S063	A0A3G2S3F8	Mitogen-activated protein kinase.	Serine/threonine-protein phosphatase.	0.425
CPK1	sck1	A0A3G2S063	A0A3G2S264	Mitogen-activated protein kinase.	Non-specific serine/threonine protein kinase.	0.456
CPR	DNF11_0086	A0A3G2RZ56	A0A3G2RZR2	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Hamartin protein.	0.412
CPR	DNF11_3215	A0A3G2RZ56	A0A3G2S7U5	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Flavin_Reduct domain-containing protein.	0.401
CPR	HSP81-3	A0A3G2RZ56	A0A3G2SB54	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	Heat shock protein 81-3.	0.412
DNF11_0086	CPR	A0A3G2RZR2	A0A3G2RZ56	Hamartin protein.	NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family.	0.412
DNF11_0086	DNF11_1732	A0A3G2RZR2	A0A3G2S5W1	Hamartin protein.	Uncharacterized protein.	0.410
DNF11_0086	RPL40	A0A3G2RZR2	A0A3G2S356	Hamartin protein.	60S ribosomal protein L40.	0.444
DNF11_0086	RPS27A	A0A3G2RZR2	A0A3G2S3X0	Hamartin protein.	40S ribosomal protein S27a.	0.444
DNF11_0086	tor2	A0A3G2RZR2	A0A3G2SAL4	Hamartin protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.756
DNF11_1336	sin1	A0A3G2S3E3	A0A3G2SA59	HbrB-like protein.	Stress-activated map kinase-interacting protein 1.	0.719
DNF11_1336	tor2	A0A3G2S3E3	A0A3G2SAL4	HbrB-like protein.	Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.	0.770