(17 nodes) Base excision repair network (Malassezia globosa)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	MGL_0150	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
	NTH1	Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the OMP decarboxylase family. (663 aa)
	MGL_0418	DNA_pol_E_B domain-containing protein. (192 aa)
	MGL_0419	DNA_pol_D_N domain-containing protein. (218 aa)
	MGL_0515	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2189 aa)
	MGL_1481	Uncharacterized protein. (168 aa)
	MGL_1506	DNA_LIGASE_A3 domain-containing protein. (701 aa)
	MGL_1620	CBFD_NFYB_HMF domain-containing protein. (222 aa)
	MGL_1726	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (525 aa)
	MGL_1813	Uncharacterized protein. (229 aa)
	MGL_2659	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (625 aa)
	MGL_2765	UDG domain-containing protein. (272 aa)
	MGL_3103	Uncharacterized protein. (337 aa)
	MGL_3205	Endo/exonuclease/phosphatase domain-containing protein. (317 aa)
	MGL_3602	ENDO3c domain-containing protein. (339 aa)
	MGL_4003	DNA polymerase. (970 aa)
	MGL_4225	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family. (342 aa)

Your Current Organism:

Malassezia globosa

NCBI taxonomy Id: 425265
Other names: M. globosa CBS 7966, Malassezia globosa CBS 7966

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MGL_0150	MGL_0418	A8PRX6	A8PTF9	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA_pol_E_B domain-containing protein.	0.888
MGL_0150	MGL_0419	A8PRX6	A8PTG1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA_pol_D_N domain-containing protein.	0.888
MGL_0150	MGL_0515	A8PRX6	A8PU18	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.921
MGL_0150	MGL_1506	A8PRX6	A8PXR2	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA_LIGASE_A3 domain-containing protein.	0.969
MGL_0150	MGL_1726	A8PRX6	A8PYU5	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.740
MGL_0150	MGL_1813	A8PRX6	A8Q1N1	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.567
MGL_0150	MGL_2659	A8PRX6	A8Q4W7	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.	0.552
MGL_0150	MGL_3103	A8PRX6	A8Q7S3	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Uncharacterized protein.	0.899
MGL_0150	MGL_3205	A8PRX6	A8Q853	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	Endo/exonuclease/phosphatase domain-containing protein.	0.581
MGL_0150	MGL_4003	A8PRX6	A8QCF6	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA polymerase.	0.963
MGL_0150	MGL_4225	A8PRX6	A8QDP4	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	DNA-(apurinic or apyrimidinic site) lyase; Belongs to the DNA repair enzymes AP/ExoA family.	0.581
MGL_0418	MGL_0150	A8PTF9	A8PRX6	DNA_pol_E_B domain-containing protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.888
MGL_0418	MGL_0419	A8PTF9	A8PTG1	DNA_pol_E_B domain-containing protein.	DNA_pol_D_N domain-containing protein.	0.991
MGL_0418	MGL_0515	A8PTF9	A8PU18	DNA_pol_E_B domain-containing protein.	DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.	0.856
MGL_0418	MGL_1481	A8PTF9	A8PXM4	DNA_pol_E_B domain-containing protein.	Uncharacterized protein.	0.965
MGL_0418	MGL_1506	A8PTF9	A8PXR2	DNA_pol_E_B domain-containing protein.	DNA_LIGASE_A3 domain-containing protein.	0.689
MGL_0418	MGL_1726	A8PTF9	A8PYU5	DNA_pol_E_B domain-containing protein.	DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family.	0.791
MGL_0418	MGL_3103	A8PTF9	A8Q7S3	DNA_pol_E_B domain-containing protein.	Uncharacterized protein.	0.495
MGL_0418	MGL_3205	A8PTF9	A8Q853	DNA_pol_E_B domain-containing protein.	Endo/exonuclease/phosphatase domain-containing protein.	0.424
MGL_0418	MGL_4003	A8PTF9	A8QCF6	DNA_pol_E_B domain-containing protein.	DNA polymerase.	0.997