(6 nodes) RNA polymerase, and Transcription termination network (Methylobacterium sp. 446)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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gene neighborhood

gene fusions

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textmining

co-expression

protein homology

Your Input:
	rpoZ	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (137 aa)
	rpoC	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1400 aa)
	rpoB	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1374 aa)
	nusG	NusG antitermination factor; Participates in transcription elongation, termination and antitermination. (177 aa)
	nusA	NusA antitermination factor; Participates in both transcription termination and antitermination. (544 aa)
	rpoD	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (666 aa)

Your Current Organism:

Methylobacterium sp. 446

NCBI taxonomy Id: 426117
Other names: M. sp. 4-46, Methylobacterium sp. 4-46

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
nusA	nusG	M446_2613	M446_0367	NusA antitermination factor; Participates in both transcription termination and antitermination.	NusG antitermination factor; Participates in transcription elongation, termination and antitermination.	0.983
nusA	rpoB	M446_2613	M446_0360	NusA antitermination factor; Participates in both transcription termination and antitermination.	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.992
nusA	rpoC	M446_2613	M446_0359	NusA antitermination factor; Participates in both transcription termination and antitermination.	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.989
nusA	rpoD	M446_2613	M446_6775	NusA antitermination factor; Participates in both transcription termination and antitermination.	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.941
nusA	rpoZ	M446_2613	M446_0030	NusA antitermination factor; Participates in both transcription termination and antitermination.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.939
nusG	nusA	M446_0367	M446_2613	NusG antitermination factor; Participates in transcription elongation, termination and antitermination.	NusA antitermination factor; Participates in both transcription termination and antitermination.	0.983
nusG	rpoB	M446_0367	M446_0360	NusG antitermination factor; Participates in transcription elongation, termination and antitermination.	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.988
nusG	rpoC	M446_0367	M446_0359	NusG antitermination factor; Participates in transcription elongation, termination and antitermination.	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.958
nusG	rpoD	M446_0367	M446_6775	NusG antitermination factor; Participates in transcription elongation, termination and antitermination.	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.683
nusG	rpoZ	M446_0367	M446_0030	NusG antitermination factor; Participates in transcription elongation, termination and antitermination.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.760
rpoB	nusA	M446_0360	M446_2613	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	NusA antitermination factor; Participates in both transcription termination and antitermination.	0.992
rpoB	nusG	M446_0360	M446_0367	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	NusG antitermination factor; Participates in transcription elongation, termination and antitermination.	0.988
rpoB	rpoC	M446_0360	M446_0359	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoB	rpoD	M446_0360	M446_6775	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.970
rpoB	rpoZ	M446_0360	M446_0030	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.994
rpoC	nusA	M446_0359	M446_2613	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	NusA antitermination factor; Participates in both transcription termination and antitermination.	0.989
rpoC	nusG	M446_0359	M446_0367	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	NusG antitermination factor; Participates in transcription elongation, termination and antitermination.	0.958
rpoC	rpoB	M446_0359	M446_0360	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
rpoC	rpoD	M446_0359	M446_6775	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase, sigma 70 subunit, RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.	0.952
rpoC	rpoZ	M446_0359	M446_0030	DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.	0.982