STRINGSTRING
SET45864.1 SET45864.1 SET46061.1 SET46061.1 SET46899.1 SET46899.1 mutS2 mutS2 SET59862.1 SET59862.1 dnaX dnaX SET72253.1 SET72253.1 SET75405.1 SET75405.1 SET80430.1 SET80430.1 SES65253.1 SES65253.1 SES65326.1 SES65326.1 polC polC mutS mutS mutL mutL lexA lexA xseB xseB xseA xseA SES73523.1 SES73523.1 SES86106.1 SES86106.1 SES89825.1 SES89825.1 ligA ligA SES93956.1 SES93956.1 SES96246.1 SES96246.1 SES99385.1 SES99385.1 addA addA SET16428.1 SET16428.1 SET22686.1 SET22686.1 SET23592.1 SET23592.1 SET26857.1 SET26857.1 SET30114.1 SET30114.1 SET30266.1 SET30266.1 SET41957.1 SET41957.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SET45864.1LexA DNA binding domain-containing protein. (84 aa)
SET46061.1D12 class N6 adenine-specific DNA methyltransferase. (461 aa)
SET46899.1DNA polymerase III catalytic subunit, DnaE type. (1157 aa)
mutS2DNA mismatch repair protein MutS2; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (791 aa)
SET59862.1Single-strand binding protein family protein. (210 aa)
dnaXDNA polymerase-3 subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (556 aa)
SET72253.1DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
SET75405.1Single-strand binding protein. (146 aa)
SET80430.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (768 aa)
SES65253.1DNA helicase-2 / ATP-dependent DNA helicase PcrA. (706 aa)
SES65326.1LexA DNA binding domain-containing protein. (81 aa)
polCDNA polymerase III catalytic subunit, PolC type; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (1440 aa)
mutSDNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (872 aa)
mutLDNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (614 aa)
lexASOS-response transcriptional repressor, LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (208 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (75 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (414 aa)
SES73523.1single-stranded-DNA-specific exonuclease. (847 aa)
SES86106.1SurA N-terminal domain-containing protein. (225 aa)
SES89825.1ATP-dependent DNA helicase PcrA. (726 aa)
ligADNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (665 aa)
SES93956.1MutS domain V. (548 aa)
SES96246.1Peptidyl-prolyl cis-trans isomerase C. (249 aa)
SES99385.1Superoxide dismutase, Fe-Mn family; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (203 aa)
addADNA helicase/exodeoxyribonuclease V, subunit A; ATP-dependent DNA helicase. (1192 aa)
SET16428.1MutS domain V; Belongs to the DNA mismatch repair MutS family. (603 aa)
SET22686.1Foldase protein PrsA. (325 aa)
SET23592.1DNA polymerase III, delta prime subunit. (331 aa)
SET26857.1Metallo-beta-lactamase family protein. (543 aa)
SET30114.1CRISPR-associated exonuclease, Cas4 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family. (163 aa)
SET30266.1MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity. Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (644 aa)
SET41957.1DNA polymerase III, delta subunit. (344 aa)
Your Current Organism:
Natronincola peptidivorans
NCBI taxonomy Id: 426128
Other names: DSM 18979, N. peptidivorans, Natronincola peptidivorans corrig. Zhilina et al. 2009, Natronincola peptidovorans, VKM B-2503, strain Z-7031
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