(117 nodes) Positive regulation of transcription by RNA polymerase II network (Pyrenophora triticirepentis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	PTRG_04116	C2H2 type zinc finger domain containing protein. (723 aa)
	PTRG_03035	Histone deacetylase 6. (1164 aa)
	PTRG_03020	Uncharacterized protein. (163 aa)
	PTRG_02906	Uncharacterized protein. (573 aa)
	PTRG_02716	26S protease regulatory subunit S10B; Belongs to the AAA ATPase family. (393 aa)
	PTRG_02688	Uncharacterized protein. (498 aa)
	PTRG_02685	Multiprotein-bridging factor 1. (158 aa)
	PTRG_02542	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1416 aa)
	PTRG_02467	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1029 aa)
	PTRG_02429	Plus3 domain-containing protein. (501 aa)
	PTRG_02422	Uncharacterized protein. (275 aa)
	PTRG_02401	Zn(2)-C6 fungal-type domain-containing protein. (1056 aa)
	PTRG_03339	26S protease regulatory subunit 6B; Belongs to the AAA ATPase family. (421 aa)
	PTRG_03180	CP2 domain-containing protein. (813 aa)
	MED10	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (142 aa)
	PTRG_00223	Fork head transcription factor 1. (866 aa)
	PTRG_01547	Uncharacterized protein. (196 aa)
	PTRG_01486	Uncharacterized protein. (520 aa)
	PTRG_01287	Transcriptional repressor rco-1. (593 aa)
	PTRG_01281	Nuclear transcription factor Y subunit C-3. (312 aa)
	PTRG_01232	BZIP domain-containing protein. (160 aa)
	PTRG_02266	ISWI chromatin-remodeling complex ATPase ISW2. (1002 aa)
	PTRG_01176	Forkhead box protein J2. (768 aa)
	PTRG_00421	TMF_TATA_bd domain-containing protein. (893 aa)
	PTRG_00506	HMG box protein. (513 aa)
	PTRG_00444	C-myc binding protein. (162 aa)
	PTRG_00486	Zinc finger protein 383. (680 aa)
	PTRG_00119	Uncharacterized protein. (381 aa)
	PTRG_00091	pH-response transcription factor pacC/RIM101. (591 aa)
	KAE1	tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (353 aa)
	PTRG_01735	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (709 aa)
	PTRG_00641	Serine/threonine-protein kinase bur1. (560 aa)
	PTRG_01827	Transcription factor prr1. (586 aa)
	PTRG_00750	Cell differentiation protein rcd1. (329 aa)
	PTRG_01912	Uncharacterized protein. (315 aa)
	PTRG_01953	Uncharacterized protein. (311 aa)
	PTRG_01954	PC4 domain-containing protein. (175 aa)
	PTRG_00853	Uncharacterized protein. (798 aa)
	PTRG_00886	Uncharacterized protein. (409 aa)
	PTRG_01011	GTPase inhibitor. (208 aa)
	PTRG_01024	Helicase SWR1. (1760 aa)
	PTRG_01072	Esterase/lipase/thioesterase. (343 aa)
	PTRG_01131	Zinc finger protein OZF. (457 aa)
	PTRG_01137	SNF2 family ATP-dependent chromatin-remodeling factor snf21. (1273 aa)
	PTRG_01157	Alpha/beta hydrolase fold-3 domain containing protein. (355 aa)
	PTRG_06746	DUF3835 domain-containing protein. (613 aa)
	PTRG_06399	Uncharacterized protein. (121 aa)
	PTRG_06006	Uncharacterized protein. (255 aa)
	PTRG_05599	Zn(2)-C6 fungal-type domain-containing protein. (769 aa)
	PTRG_05544	Zn(2)-C6 fungal-type domain-containing protein. (970 aa)
	PTRG_05496	Beta-lactamase family protein. (410 aa)
	PTRG_05354	MADS box transcription factor Mcm1. (220 aa)
	PTRG_06159	TPR repeat-containing protein. (870 aa)
	PTRG_07170	FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (582 aa)
	PTRG_07202	RING finger domain containing protein. (723 aa)
	PTRG_07232	ATPase family AAA domain-containing protein 2. (1619 aa)
	PTRG_07329	Med12 domain-containing protein. (1566 aa)
	PTRG_07348	SET domain containing protein. (646 aa)
	PTRG_06977	RPEL repeat protein. (143 aa)
	PTRG_07153	Phosphorus acquisition-controlling protein. (750 aa)
	PTRG_07874	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (56 aa)
	PTRG_07916	BHLH domain-containing protein. (448 aa)
	PTRG_07945	Nuclear transcription factor Y subunit B-10. (188 aa)
	PTRG_08080	SRF-type transcription factor RlmA. (634 aa)
	PTRG_08299	Acetyl-hydrolase. (488 aa)
	PTRG_08409	Transcriptional activator hacA. (307 aa)
	PTRG_08525	Homeobox domain-containing protein. (364 aa)
	PTRG_08532	26S protease regulatory subunit 6A; Belongs to the AAA ATPase family. (460 aa)
	PTRG_08665	Quinic acid utilization activator. (691 aa)
	PTRG_08131	26S protease regulatory subunit 8; Belongs to the AAA ATPase family. (389 aa)
	PTRG_08153	Acid phosphatase (PhoG). (534 aa)
	PTRG_08168	TATA-binding protein-associated phosphoprotein. (132 aa)
	PTRG_08710	Uncharacterized protein. (533 aa)
	PTRG_08793	Serine/threonine-protein kinase crk1. (372 aa)
	PTRG_08865	Myb-like domain-containing protein. (546 aa)
	PTRG_08916	C2H2-type domain-containing protein. (325 aa)
	PTRG_08944	C6 zinc finger domain containing protein. (698 aa)
	PTRG_08977	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (113 aa)
	PTRG_08987	Uncharacterized protein. (89 aa)
	PTRG_09110	ISWI chromatin-remodeling complex ATPase ISW2. (1271 aa)
	PTRG_09130	Quinic acid utilization activator. (648 aa)
	PTRG_09160	GATA factor SREP. (443 aa)
	PTRG_09415	Uncharacterized protein. (305 aa)
	PTRG_09422	Fungal_trans domain-containing protein. (658 aa)
	PTRG_09630	DNA polymerase epsilon subunit C. (161 aa)
	PTRG_09646	Uncharacterized protein. (82 aa)
	PTRG_09789	Zn(2)-C6 fungal-type domain-containing protein. (542 aa)
	PTRG_09846	Uncharacterized protein. (684 aa)
	PTRG_09921	Zn(2)-C6 fungal-type domain-containing protein. (769 aa)
	PTRG_09999	SGF29 C-terminal domain-containing protein. (362 aa)
	PTRG_10001	Uncharacterized protein. (271 aa)
	PTRG_10044	Uncharacterized protein. (258 aa)
	PTRG_10423	HMG box domain-containing protein. (359 aa)
	PTRG_10439	Uncharacterized protein. (250 aa)
	PTRG_10573	F-box domain-containing protein. (492 aa)
	PTRG_10600	C6 zinc finger domain containing protein. (615 aa)
	PTRG_10928	Serine/threonine-protein kinase bur1; Belongs to the protein kinase superfamily. (450 aa)
	PTRG_10964	BRCT domain containing protein. (1551 aa)
	PTRG_11139	NDT80 domain-containing protein. (529 aa)
	PTRG_11164	RNA polymerase II accessory factor. (421 aa)
	PTRG_11191	PAS domain-containing protein. (498 aa)
	PTRG_11232	Uncharacterized protein. (431 aa)
	PTRG_11389	HLH transcription factor (GlcD gamma). (543 aa)
	PTRG_11766	HTH CENPB-type domain-containing protein. (140 aa)
	PTRG_11872	Transcription factor TFIIF complex alpha subunit Tfg1. (701 aa)
	PTRG_06095	Uncharacterized protein. (144 aa)
	PTRG_04801	BHLH domain-containing protein. (125 aa)
	PTRG_04465	Uncharacterized protein. (651 aa)
	PTRG_05285	Start control protein cdc10. (845 aa)
	PTRG_05162	Trichome differentiation protein GL1. (399 aa)
	PTRG_05102	Uncharacterized protein. (360 aa)
	PTRG_05029	GATA type zinc finger protein Asd4. (277 aa)
	PTRG_04965	UDP-N-acetylglucosaminyltransferase. (1529 aa)
	PTRG_03705	Uncharacterized protein. (582 aa)
	PTRG_03699	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (698 aa)
	PTRG_03674	JmjC domain-containing histone demethylation protein 3D. (1291 aa)
	PTRG_04214	E3 ubiquitin-protein ligase. (817 aa)

Your Current Organism:

Pyrenophora triticirepentis

NCBI taxonomy Id: 426418
Other names: P. tritici-repentis Pt-1C-BFP, Pyrenophora tritici-repentis Pt-1C-BFP

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MED10	PTRG_01735	B2VX09	B2VSA9	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	0.747
MED10	PTRG_07329	B2VX09	B2WAL6	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Med12 domain-containing protein.	0.478
MED10	PTRG_08793	B2VX09	B2WFT7	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Serine/threonine-protein kinase crk1.	0.581
MED10	PTRG_08977	B2VX09	B2WGC1	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family.	0.868
MED10	PTRG_11872	B2VX09	B2WPG2	Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.	Transcription factor TFIIF complex alpha subunit Tfg1.	0.903
PTRG_00091	PTRG_00486	B2VRK9	B2VR59	pH-response transcription factor pacC/RIM101.	Zinc finger protein 383.	0.436
PTRG_00091	PTRG_01131	B2VRK9	B2VV64	pH-response transcription factor pacC/RIM101.	Zinc finger protein OZF.	0.412
PTRG_00091	PTRG_01287	B2VRK9	B2VVS5	pH-response transcription factor pacC/RIM101.	Transcriptional repressor rco-1.	0.425
PTRG_00091	PTRG_02906	B2VRK9	B2VZR6	pH-response transcription factor pacC/RIM101.	Uncharacterized protein.	0.459
PTRG_00091	PTRG_04116	B2VRK9	B2W0Y1	pH-response transcription factor pacC/RIM101.	C2H2 type zinc finger domain containing protein.	0.515
PTRG_00091	PTRG_08916	B2VRK9	B2WG60	pH-response transcription factor pacC/RIM101.	C2H2-type domain-containing protein.	0.436
PTRG_00223	PTRG_01176	B2VWY6	B2VVA9	Fork head transcription factor 1.	Forkhead box protein J2.	0.851
PTRG_00223	PTRG_02467	B2VWY6	B2VYH7	Fork head transcription factor 1.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.600
PTRG_00223	PTRG_04965	B2VWY6	B2W3B5	Fork head transcription factor 1.	UDP-N-acetylglucosaminyltransferase.	0.699
PTRG_00223	PTRG_05029	B2VWY6	B2W3H9	Fork head transcription factor 1.	GATA type zinc finger protein Asd4.	0.535
PTRG_00223	PTRG_05285	B2VWY6	B2W485	Fork head transcription factor 1.	Start control protein cdc10.	0.505
PTRG_00223	PTRG_05354	B2VWY6	B2W6B6	Fork head transcription factor 1.	MADS box transcription factor Mcm1.	0.734
PTRG_00223	PTRG_08080	B2VWY6	B2WDM1	Fork head transcription factor 1.	SRF-type transcription factor RlmA.	0.480
PTRG_00223	PTRG_09160	B2VWY6	B2WGV4	Fork head transcription factor 1.	GATA factor SREP.	0.589
PTRG_00223	PTRG_09630	B2VWY6	B2WI21	Fork head transcription factor 1.	DNA polymerase epsilon subunit C.	0.404