(39 nodes) Spliceosomal snRNP complex, and SLBP independent Processing of Histone Pre-mRNAs network (Fusarium nygamai)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNYG_15682	Uncharacterized protein; Belongs to the DEAD box helicase family. (723 aa)
	FNYG_14226	WD_REPEATS_REGION domain-containing protein. (354 aa)
	FNYG_13729	Uncharacterized protein. (321 aa)
	FNYG_13449	Small nuclear ribonucleoprotein G. (91 aa)
	FNYG_13376	Sm domain-containing protein. (207 aa)
	FNYG_12611	Uncharacterized protein. (357 aa)
	FNYG_12515	Uncharacterized protein. (534 aa)
	FNYG_11713	Uncharacterized protein. (2206 aa)
	FNYG_11571	JAB_MPN domain-containing protein. (2369 aa)
	FNYG_11379	Splicing factor subunit; Belongs to the SF3B5 family. (121 aa)
	FNYG_10753	Uncharacterized protein. (243 aa)
	FNYG_10195	CPSF_A domain-containing protein. (559 aa)
	FNYG_10196	Uncharacterized protein. (490 aa)
	FNYG_09434	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (199 aa)
	FNYG_09439	Uncharacterized protein. (321 aa)
	FNYG_09194	RRM domain-containing protein. (116 aa)
	FNYG_09260	WD_REPEATS_REGION domain-containing protein. (519 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (99 aa)
	FNYG_09381	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (123 aa)
	FNYG_09031	Uncharacterized protein. (167 aa)
	FNYG_09054	Uncharacterized protein. (1301 aa)
	FNYG_09123	RRM domain-containing protein. (203 aa)
	FNYG_08961	Matrin-type domain-containing protein. (240 aa)
	FNYG_08716	Matrin-type domain-containing protein. (501 aa)
	FNYG_08549	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (96 aa)
	FNYG_08286	RRM domain-containing protein. (391 aa)
	FNYG_07641	Sm domain-containing protein. (89 aa)
	FNYG_06365	Nop domain-containing protein. (630 aa)
	FNYG_06324	Uncharacterized protein. (930 aa)
	FNYG_03273	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (143 aa)
	FNYG_03297	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	FNYG_03331	SF3b1 domain-containing protein. (1210 aa)
	FNYG_03250	Uncharacterized protein. (243 aa)
	FNYG_02118	Uncharacterized protein. (643 aa)
	FNYG_01728	Small nuclear ribonucleoprotein Sm D3. (115 aa)
	FNYG_00934	Tr-type G domain-containing protein. (1000 aa)
	FNYG_00541	PSP domain-containing protein. (603 aa)
	FNYG_00344	Uncharacterized protein. (110 aa)
	FNYG_00047	Uncharacterized protein. (485 aa)

Your Current Organism:

Fusarium nygamai

NCBI taxonomy Id: 42673
Other names: ATCC 58555, BBA 69862, CBS 749.97, DAOM 225148, F. nygamai, Gibberella nygamai, IMI 375354, NRRL 13448

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FNYG_00047	FNYG_00344	A0A2K0WWD2	A0A2K0WVN9	Uncharacterized protein.	Uncharacterized protein.	0.914
FNYG_00047	FNYG_00541	A0A2K0WWD2	A0A2K0WVL1	Uncharacterized protein.	PSP domain-containing protein.	0.983
FNYG_00047	FNYG_00934	A0A2K0WWD2	A0A2K0WUC3	Uncharacterized protein.	Tr-type G domain-containing protein.	0.988
FNYG_00047	FNYG_01728	A0A2K0WWD2	A0A2K0WRN3	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D3.	0.962
FNYG_00047	FNYG_02118	A0A2K0WWD2	A0A2K0WQD3	Uncharacterized protein.	Uncharacterized protein.	0.995
FNYG_00047	FNYG_03250	A0A2K0WWD2	A0A2K0WN29	Uncharacterized protein.	Uncharacterized protein.	0.889
FNYG_00047	FNYG_03273	A0A2K0WWD2	A0A2K0WL07	Uncharacterized protein.	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	0.979
FNYG_00047	FNYG_03297	A0A2K0WWD2	A0A2K0WL25	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D2.	0.983
FNYG_00047	FNYG_03331	A0A2K0WWD2	A0A2K0WL55	Uncharacterized protein.	SF3b1 domain-containing protein.	0.964
FNYG_00047	FNYG_06324	A0A2K0WWD2	A0A2K0WEK3	Uncharacterized protein.	Uncharacterized protein.	0.993
FNYG_00047	FNYG_06365	A0A2K0WWD2	A0A2K0WDC3	Uncharacterized protein.	Nop domain-containing protein.	0.997
FNYG_00047	FNYG_07641	A0A2K0WWD2	A0A2K0WAA6	Uncharacterized protein.	Sm domain-containing protein.	0.976
FNYG_00047	FNYG_08286	A0A2K0WWD2	A0A2K0W7S3	Uncharacterized protein.	RRM domain-containing protein.	0.848
FNYG_00047	FNYG_08549	A0A2K0WWD2	A0A2K0W754	Uncharacterized protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.986
FNYG_00047	FNYG_08716	A0A2K0WWD2	A0A2K0W6T3	Uncharacterized protein.	Matrin-type domain-containing protein.	0.952
FNYG_00047	FNYG_08961	A0A2K0WWD2	A0A2K0W5V3	Uncharacterized protein.	Matrin-type domain-containing protein.	0.963
FNYG_00047	FNYG_09031	A0A2K0WWD2	A0A2K0W5J5	Uncharacterized protein.	Uncharacterized protein.	0.952
FNYG_00047	FNYG_09054	A0A2K0WWD2	A0A2K0W5M2	Uncharacterized protein.	Uncharacterized protein.	0.678
FNYG_00047	FNYG_09123	A0A2K0WWD2	A0A2K0W5T1	Uncharacterized protein.	RRM domain-containing protein.	0.889
FNYG_00047	FNYG_09194	A0A2K0WWD2	A0A2K0W4W6	Uncharacterized protein.	RRM domain-containing protein.	0.677