(10 nodes) RNA polymerase II, core complex network (Fusarium nygamai)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPB2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1270 aa)
	FNYG_13418	RPOL4c domain-containing protein. (158 aa)
	FNYG_12622	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (1047 aa)
	FNYG_12050	RNA_pol_L_2 domain-containing protein. (143 aa)
	FNYG_11912	Uncharacterized protein. (72 aa)
	FNYG_11724	Uncharacterized protein. (172 aa)
	FNYG_10249	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene. (123 aa)
	FNYG_07569	RPOLD domain-containing protein. (340 aa)
	FNYG_04460	RPOL9 domain-containing protein. (186 aa)
	RPB1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1744 aa)

Your Current Organism:

Fusarium nygamai

NCBI taxonomy Id: 42673
Other names: ATCC 58555, BBA 69862, CBS 749.97, DAOM 225148, F. nygamai, Gibberella nygamai, IMI 375354, NRRL 13448

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FNYG_04460	FNYG_07569	A0A2K0WJ16	A0A2K0WA69	RPOL9 domain-containing protein.	RPOLD domain-containing protein.	0.997
FNYG_04460	FNYG_10249	A0A2K0WJ16	A0A2K0W2B3	RPOL9 domain-containing protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.993
FNYG_04460	FNYG_11724	A0A2K0WJ16	A0A2K0VY33	RPOL9 domain-containing protein.	Uncharacterized protein.	0.997
FNYG_04460	FNYG_11912	A0A2K0WJ16	A0A2K0VXN5	RPOL9 domain-containing protein.	Uncharacterized protein.	0.998
FNYG_04460	FNYG_12050	A0A2K0WJ16	A0A2K0VX56	RPOL9 domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.999
FNYG_04460	FNYG_12622	A0A2K0WJ16	A0A2K0VVF1	RPOL9 domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.990
FNYG_04460	FNYG_13418	A0A2K0WJ16	A0A2K0VTC8	RPOL9 domain-containing protein.	RPOL4c domain-containing protein.	0.997
FNYG_04460	RPB1	A0A2K0WJ16	A0A2K0WM34	RPOL9 domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.996
FNYG_04460	RPB2	A0A2K0WJ16	A0A2K0UTM4	RPOL9 domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.997
FNYG_07569	FNYG_04460	A0A2K0WA69	A0A2K0WJ16	RPOLD domain-containing protein.	RPOL9 domain-containing protein.	0.997
FNYG_07569	FNYG_10249	A0A2K0WA69	A0A2K0W2B3	RPOLD domain-containing protein.	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.995
FNYG_07569	FNYG_11724	A0A2K0WA69	A0A2K0VY33	RPOLD domain-containing protein.	Uncharacterized protein.	0.997
FNYG_07569	FNYG_11912	A0A2K0WA69	A0A2K0VXN5	RPOLD domain-containing protein.	Uncharacterized protein.	0.997
FNYG_07569	FNYG_12050	A0A2K0WA69	A0A2K0VX56	RPOLD domain-containing protein.	RNA_pol_L_2 domain-containing protein.	0.998
FNYG_07569	FNYG_12622	A0A2K0WA69	A0A2K0VVF1	RPOLD domain-containing protein.	Transcription elongation factor SPT5; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	0.995
FNYG_07569	FNYG_13418	A0A2K0WA69	A0A2K0VTC8	RPOLD domain-containing protein.	RPOL4c domain-containing protein.	0.997
FNYG_07569	RPB1	A0A2K0WA69	A0A2K0WM34	RPOLD domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.997
FNYG_07569	RPB2	A0A2K0WA69	A0A2K0UTM4	RPOLD domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
FNYG_10249	FNYG_04460	A0A2K0W2B3	A0A2K0WJ16	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	RPOL9 domain-containing protein.	0.993
FNYG_10249	FNYG_07569	A0A2K0W2B3	A0A2K0WA69	Transcription elongation factor SPT4; The SPT4-SPT5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene.	RPOLD domain-containing protein.	0.995