(56 nodes) RNA polymerase II, holoenzyme network (Fusarium nygamai)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RPB2	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1270 aa)
	FNYG_14562	Uncharacterized protein. (442 aa)
	FNYG_14793	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (413 aa)
	FNYG_14829	Uncharacterized protein. (427 aa)
	FNYG_15981	Uncharacterized protein. (434 aa)
	FNYG_13737	TAF domain-containing protein. (463 aa)
	FNYG_13392	BTP domain-containing protein. (232 aa)
	FNYG_13418	RPOL4c domain-containing protein. (158 aa)
	FNYG_13410	Uncharacterized protein. (373 aa)
	FNYG_13314	WD_REPEATS_REGION domain-containing protein. (314 aa)
	FNYG_13343	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (468 aa)
	FNYG_13072	PHD domain-containing protein. (718 aa)
	FNYG_13002	Uncharacterized protein. (470 aa)
	FNYG_12050	RNA_pol_L_2 domain-containing protein. (143 aa)
	FNYG_11912	Uncharacterized protein. (72 aa)
	FNYG_11798	Uncharacterized protein. (306 aa)
	FNYG_11724	Uncharacterized protein. (172 aa)
	FNYG_11050	Uncharacterized protein. (380 aa)
	FNYG_11065	Uncharacterized protein. (236 aa)
	FNYG_10910	TFIID_20kDa domain-containing protein. (687 aa)
	FNYG_10757	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (115 aa)
	FNYG_10407	CDC73_C domain-containing protein. (409 aa)
	FNYG_10177	Uncharacterized protein. (499 aa)
	FNYG_10049	Uncharacterized protein. (763 aa)
	FNYG_09211	Uncharacterized protein. (406 aa)
	FNYG_09316	Uncharacterized protein. (416 aa)
	FNYG_09077	TAFII55_N domain-containing protein. (493 aa)
	FNYG_08872	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (188 aa)
	FNYG_08720	TAFII28 domain-containing protein. (320 aa)
	FNYG_08263	Uncharacterized protein. (154 aa)
	FNYG_08396	Uncharacterized protein. (475 aa)
	FNYG_08381	Uncharacterized protein. (825 aa)
	FNYG_07569	RPOLD domain-containing protein. (340 aa)
	FNYG_06955	Plus3 domain-containing protein. (596 aa)
	FNYG_06458	Uncharacterized protein. (1214 aa)
	FNYG_05663	ANK_REP_REGION domain-containing protein. (1762 aa)
	FNYG_05134	Uncharacterized protein. (356 aa)
	FNYG_04589	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (496 aa)
	FNYG_04460	RPOL9 domain-containing protein. (186 aa)
	FNYG_04282	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (304 aa)
	FNYG_03595	Uncharacterized protein. (253 aa)
	FNYG_03626	Uncharacterized protein. (80 aa)
	RPB1	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1744 aa)
	FNYG_03226	Uncharacterized protein. (665 aa)
	FNYG_03237	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa)
	FNYG_02173	Uncharacterized protein. (163 aa)
	FNYG_01801	Uncharacterized protein. (758 aa)
	FNYG_01896	CID domain-containing protein. (406 aa)
	FNYG_01913	HTH TFE/IIEalpha-type domain-containing protein. (385 aa)
	FNYG_01955	Uncharacterized protein. (578 aa)
	FNYG_01389	Cyclin_C_2 domain-containing protein. (348 aa)
	FNYG_00767	Uncharacterized protein. (1499 aa)
	FNYG_00966	DUF3591 domain-containing protein. (1300 aa)
	FNYG_01096	RING-type domain-containing protein. (363 aa)
	FNYG_00050	Helicase ATP-binding domain-containing protein. (748 aa)
	FNYG_00065	BSD domain-containing protein. (645 aa)

Your Current Organism:

Fusarium nygamai

NCBI taxonomy Id: 42673
Other names: ATCC 58555, BBA 69862, CBS 749.97, DAOM 225148, F. nygamai, Gibberella nygamai, IMI 375354, NRRL 13448

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FNYG_00050	FNYG_00065	A0A2K0WWD5	A0A2K0WWF4	Helicase ATP-binding domain-containing protein.	BSD domain-containing protein.	0.997
FNYG_00050	FNYG_00767	A0A2K0WWD5	A0A2K0WTU6	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.893
FNYG_00050	FNYG_00966	A0A2K0WWD5	A0A2K0WUG5	Helicase ATP-binding domain-containing protein.	DUF3591 domain-containing protein.	0.857
FNYG_00050	FNYG_01096	A0A2K0WWD5	A0A2K0WUU1	Helicase ATP-binding domain-containing protein.	RING-type domain-containing protein.	0.997
FNYG_00050	FNYG_01389	A0A2K0WWD5	A0A2K0WSD1	Helicase ATP-binding domain-containing protein.	Cyclin_C_2 domain-containing protein.	0.992
FNYG_00050	FNYG_01801	A0A2K0WWD5	A0A2K0WQZ9	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.857
FNYG_00050	FNYG_01913	A0A2K0WWD5	A0A2K0WRB8	Helicase ATP-binding domain-containing protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.994
FNYG_00050	FNYG_02173	A0A2K0WWD5	A0A2K0WQM7	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.893
FNYG_00050	FNYG_03226	A0A2K0WWD5	A0A2K0WN15	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.979
FNYG_00050	FNYG_03237	A0A2K0WWD5	A0A2K0WN32	Helicase ATP-binding domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.975
FNYG_00050	FNYG_03595	A0A2K0WWD5	A0A2K0WLY0	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.860
FNYG_00050	FNYG_03626	A0A2K0WWD5	A0A2K0WM13	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.978
FNYG_00050	FNYG_04282	A0A2K0WWD5	A0A2K0WJW5	Helicase ATP-binding domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.994
FNYG_00050	FNYG_04460	A0A2K0WWD5	A0A2K0WJ16	Helicase ATP-binding domain-containing protein.	RPOL9 domain-containing protein.	0.976
FNYG_00050	FNYG_04589	A0A2K0WWD5	A0A2K0WIC4	Helicase ATP-binding domain-containing protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.996
FNYG_00050	FNYG_05134	A0A2K0WWD5	A0A2K0WH82	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.997
FNYG_00050	FNYG_07569	A0A2K0WWD5	A0A2K0WA69	Helicase ATP-binding domain-containing protein.	RPOLD domain-containing protein.	0.981
FNYG_00050	FNYG_08263	A0A2K0WWD5	A0A2K0W7Q7	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.977
FNYG_00050	FNYG_08381	A0A2K0WWD5	A0A2K0W833	Helicase ATP-binding domain-containing protein.	Uncharacterized protein.	0.979
FNYG_00050	FNYG_08720	A0A2K0WWD5	A0A2K0W6V1	Helicase ATP-binding domain-containing protein.	TAFII28 domain-containing protein.	0.893