(11 nodes) Mitotic DNA damage checkpoint signaling network (Fusarium nygamai)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	FNYG_03092	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (463 aa)
	FNYG_06974	MRC1 domain-containing protein. (1294 aa)
	FNYG_07527	Protein kinase domain-containing protein. (553 aa)
	FNYG_08532	Uncharacterized protein. (828 aa)
	FNYG_11831	Uncharacterized protein. (348 aa)
	FNYG_08820	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (724 aa)
	FNYG_08812	ERCC4 domain-containing protein. (676 aa)
	FNYG_10296	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
	FNYG_00794	FHA domain-containing protein. (795 aa)
	FNYG_09294	Uncharacterized protein. (1198 aa)
	FNYG_02178	Checkpoint protein; Belongs to the HUS1 family. (344 aa)

Your Current Organism:

Fusarium nygamai

NCBI taxonomy Id: 42673
Other names: ATCC 58555, BBA 69862, CBS 749.97, DAOM 225148, F. nygamai, Gibberella nygamai, IMI 375354, NRRL 13448

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FNYG_00794	FNYG_02178	A0A2K0WTZ2	A0A2K0WQJ0	FHA domain-containing protein.	Checkpoint protein; Belongs to the HUS1 family.	0.809
FNYG_00794	FNYG_03092	A0A2K0WTZ2	A0A2K0WMM1	FHA domain-containing protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.810
FNYG_00794	FNYG_07527	A0A2K0WTZ2	A0A2K0W9X3	FHA domain-containing protein.	Protein kinase domain-containing protein.	0.775
FNYG_00794	FNYG_08532	A0A2K0WTZ2	A0A2K0W703	FHA domain-containing protein.	Uncharacterized protein.	0.901
FNYG_00794	FNYG_08820	A0A2K0WTZ2	A0A2K0W644	FHA domain-containing protein.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.998
FNYG_00794	FNYG_09294	A0A2K0WTZ2	A0A2K0W561	FHA domain-containing protein.	Uncharacterized protein.	0.788
FNYG_00794	FNYG_10296	A0A2K0WTZ2	A0A2K0W1U2	FHA domain-containing protein.	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.	0.428
FNYG_02178	FNYG_00794	A0A2K0WQJ0	A0A2K0WTZ2	Checkpoint protein; Belongs to the HUS1 family.	FHA domain-containing protein.	0.809
FNYG_02178	FNYG_03092	A0A2K0WQJ0	A0A2K0WMM1	Checkpoint protein; Belongs to the HUS1 family.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.998
FNYG_02178	FNYG_06974	A0A2K0WQJ0	A0A2K0WBG8	Checkpoint protein; Belongs to the HUS1 family.	MRC1 domain-containing protein.	0.637
FNYG_02178	FNYG_07527	A0A2K0WQJ0	A0A2K0W9X3	Checkpoint protein; Belongs to the HUS1 family.	Protein kinase domain-containing protein.	0.816
FNYG_02178	FNYG_08532	A0A2K0WQJ0	A0A2K0W703	Checkpoint protein; Belongs to the HUS1 family.	Uncharacterized protein.	0.894
FNYG_02178	FNYG_08820	A0A2K0WQJ0	A0A2K0W644	Checkpoint protein; Belongs to the HUS1 family.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.851
FNYG_03092	FNYG_00794	A0A2K0WMM1	A0A2K0WTZ2	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	FHA domain-containing protein.	0.810
FNYG_03092	FNYG_02178	A0A2K0WMM1	A0A2K0WQJ0	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Checkpoint protein; Belongs to the HUS1 family.	0.998
FNYG_03092	FNYG_06974	A0A2K0WMM1	A0A2K0WBG8	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	MRC1 domain-containing protein.	0.782
FNYG_03092	FNYG_07527	A0A2K0WMM1	A0A2K0W9X3	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Protein kinase domain-containing protein.	0.821
FNYG_03092	FNYG_08532	A0A2K0WMM1	A0A2K0W703	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.989
FNYG_03092	FNYG_08820	A0A2K0WMM1	A0A2K0W644	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.	0.810
FNYG_03092	FNYG_09294	A0A2K0WMM1	A0A2K0W561	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Uncharacterized protein.	0.755