(58 nodes) Nucleic acid-binding, OB-fold network (Fusarium nygamai)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	FNYG_06462	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate; Belongs to the eukaryotic GTase family. (389 aa)
	FNYG_06374	Ribosomal_L2_C domain-containing protein. (372 aa)
	FNYG_06401	Uncharacterized protein. (68 aa)
	FNYG_06412	RNB domain-containing protein. (1001 aa)
	FNYG_05136	TRAM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (542 aa)
	FNYG_04690	Uncharacterized protein. (1197 aa)
	FNYG_06439	Ribosomal_L2_C domain-containing protein. (288 aa)
	FNYG_04699	Uncharacterized protein. (389 aa)
	FNYG_04798	Uncharacterized protein. (193 aa)
	FNYG_04953	DNA ligase. (869 aa)
	FNYG_04109	Uncharacterized protein. (335 aa)
	FNYG_04125	Lysine--tRNA ligase. (609 aa)
	FNYG_04120	Uncharacterized protein. (260 aa)
	FNYG_06996	ECR1_N domain-containing protein. (331 aa)
	FNYG_06943	Transcription elongation factor Spt6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression; Belongs to the SPT6 family. (1406 aa)
	FNYG_07194	Uncharacterized protein. (107 aa)
	FNYG_08370	Uncharacterized protein. (138 aa)
	FNYG_08598	AAA domain-containing protein; Belongs to the AAA ATPase family. (459 aa)
	FNYG_08899	AAA domain-containing protein; Belongs to the AAA ATPase family. (389 aa)
	FNYG_08964	Uncharacterized protein; Belongs to the RNR ribonuclease family. (983 aa)
	FNYG_09224	DNA helicase; Belongs to the MCM family. (1006 aa)
	FNYG_09170	AAA domain-containing protein; Belongs to the AAA ATPase family. (448 aa)
	FNYG_09448	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (608 aa)
	FNYG_09701	DNA helicase; Belongs to the MCM family. (721 aa)
	FNYG_10401	S1 motif domain-containing protein. (311 aa)
	FNYG_11034	Uncharacterized protein. (269 aa)
	FNYG_10972	Uncharacterized protein. (182 aa)
	FNYG_10966	S1-like domain-containing protein. (135 aa)
	FNYG_11209	DNA helicase; Belongs to the MCM family. (957 aa)
	FNYG_11157	Uncharacterized protein. (1798 aa)
	FNYG_11450	AA_TRNA_LIGASE_II domain-containing protein. (564 aa)
	FNYG_11592	DNA helicase; Belongs to the MCM family. (889 aa)
	FNYG_11724	Uncharacterized protein. (172 aa)
	FNYG_11699	AAA domain-containing protein; Belongs to the AAA ATPase family. (391 aa)
	FNYG_13221	AAA domain-containing protein; Belongs to the AAA ATPase family. (421 aa)
	FNYG_13182	Uncharacterized protein; Belongs to the universal ribosomal protein uS12 family. (145 aa)
	FNYG_13541	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family. (173 aa)
	FNYG_14359	DNA helicase; Belongs to the MCM family. (879 aa)
	FNYG_14265	AA_TRNA_LIGASE_II domain-containing protein. (967 aa)
	FNYG_14290	Eukaryotic translation initiation factor 5A. (164 aa)
	FNYG_04164	Uncharacterized protein. (395 aa)
	FNYG_04201	AA_TRNA_LIGASE_II domain-containing protein. (582 aa)
	FNYG_04248	S1-like domain-containing protein; Belongs to the eIF-1A family. (158 aa)
	FNYG_04257	Uncharacterized protein. (245 aa)
	FNYG_03288	RNB domain-containing protein. (1360 aa)
	FNYG_03292	DNA_LIGASE_A3 domain-containing protein. (568 aa)
	MCM7	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (814 aa)
	FNYG_03432	POT1PC domain-containing protein. (503 aa)
	FNYG_03483	Telo_bind domain-containing protein. (1529 aa)
	FNYG_03514	Uncharacterized protein. (208 aa)
	FNYG_03604	AA_TRNA_LIGASE_II domain-containing protein. (637 aa)
	FNYG_03106	DNA ligase. (984 aa)
	FNYG_03237	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (148 aa)
	FNYG_01983	Uncharacterized protein. (168 aa)
	FNYG_02078	DNA ligase. (880 aa)
	FNYG_01783	AAA domain-containing protein; Belongs to the AAA ATPase family. (442 aa)
	FNYG_00654	Zf-primase domain-containing protein. (770 aa)
	FNYG_00725	Uncharacterized protein. (282 aa)

Your Current Organism:

Fusarium nygamai

NCBI taxonomy Id: 42673
Other names: ATCC 58555, BBA 69862, CBS 749.97, DAOM 225148, F. nygamai, Gibberella nygamai, IMI 375354, NRRL 13448

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FNYG_00654	FNYG_02078	A0A2K0WTJ0	A0A2K0WQ93	Zf-primase domain-containing protein.	DNA ligase.	0.451
FNYG_00654	FNYG_04953	A0A2K0WTJ0	A0A2K0WI13	Zf-primase domain-containing protein.	DNA ligase.	0.451
FNYG_00654	FNYG_09224	A0A2K0WTJ0	A0A2K0W4Z7	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.997
FNYG_00654	FNYG_09448	A0A2K0WTJ0	A0A2K0W4D9	Zf-primase domain-containing protein.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.801
FNYG_00654	FNYG_09701	A0A2K0WTJ0	A0A2K0W3U5	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.994
FNYG_00654	FNYG_11034	A0A2K0WTJ0	A0A2K0W020	Zf-primase domain-containing protein.	Uncharacterized protein.	0.713
FNYG_00654	FNYG_11209	A0A2K0WTJ0	A0A2K0VZE9	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.997
FNYG_00654	FNYG_11592	A0A2K0WTJ0	A0A2K0VYK3	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.996
FNYG_00654	FNYG_14359	A0A2K0WTJ0	A0A2K0UT41	Zf-primase domain-containing protein.	DNA helicase; Belongs to the MCM family.	0.992
FNYG_00654	MCM7	A0A2K0WTJ0	A0A2K0WLC1	Zf-primase domain-containing protein.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.997
FNYG_00725	FNYG_05136	A0A2K0WTT4	A0A2K0WH56	Uncharacterized protein.	TRAM domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.	0.459
FNYG_00725	FNYG_11157	A0A2K0WTT4	A0A2K0VZA8	Uncharacterized protein.	Uncharacterized protein.	0.504
FNYG_01783	FNYG_06439	A0A2K0WQY2	A0A2K0WD56	AAA domain-containing protein; Belongs to the AAA ATPase family.	Ribosomal_L2_C domain-containing protein.	0.621
FNYG_01783	FNYG_08598	A0A2K0WQY2	A0A2K0W767	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
FNYG_01783	FNYG_08899	A0A2K0WQY2	A0A2K0W6C4	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
FNYG_01783	FNYG_09170	A0A2K0WQY2	A0A2K0W4U1	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
FNYG_01783	FNYG_10401	A0A2K0WQY2	A0A2K0W241	AAA domain-containing protein; Belongs to the AAA ATPase family.	S1 motif domain-containing protein.	0.402
FNYG_01783	FNYG_11699	A0A2K0WQY2	A0A2K0VXZ8	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
FNYG_01783	FNYG_13221	A0A2K0WQY2	A0A2K0VTY5	AAA domain-containing protein; Belongs to the AAA ATPase family.	AAA domain-containing protein; Belongs to the AAA ATPase family.	0.999
FNYG_01783	FNYG_13541	A0A2K0WQY2	A0A2K0V9V8	AAA domain-containing protein; Belongs to the AAA ATPase family.	Ribosomal_S17_N domain-containing protein; Belongs to the universal ribosomal protein uS17 family.	0.454