Your Input: | |
| | thiM | Putative hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (273 aa) |
| | cysS | cysteine--tRNA ligase; KEGG: bha:BH0111 2.5e-103 cysS; cysteinyl-tRNA synthetase K01883; COG: COG0215 Cysteinyl-tRNA synthetase; Psort location: Cytoplasmic, score: 9.98; Belongs to the class-I aminoacyl-tRNA synthetase family. (460 aa) |
| | folC | Bifunctional protein FolC; KEGG: bca:BCE_4548 8.8e-53 folC; folylpolyglutamate synthase K01930; COG: COG0285 Folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 8.87. (386 aa) |
| | EDS74592.1 | Aminopeptidase I zinc metalloprotease (M18); KEGG: cac:CAC1091 3.3e-156 aspartyl aminopeptidase K01269; COG: COG1362 Aspartyl aminopeptidase; Psort location: Cytoplasmic, score: 8.87. (455 aa) |
| | EDS74588.1 | DHHA2 domain protein; KEGG: cpe:CPE2055 1.0e-152 probable manganase-dependent inorganic pyrophosphatase K01507; COG: COG1227 Inorganic pyrophosphatase/exopolyphosphatase; Psort location: Cytoplasmic, score: 8.87. (546 aa) |
| | tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (386 aa) |
| | queH | Hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (210 aa) |
| | EDS74574.1 | FAD dependent oxidoreductase; KEGG: mma:MM1656 1.6e-55 oxidoreductase K00100; COG: COG0665 Glycine/D-amino acid oxidases (deaminating); Psort location: Cytoplasmic, score: 8.87. (453 aa) |
| | nadA | Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (303 aa) |
| | EDS74568.1 | DnaJ domain protein; COG: COG2214 DnaJ-class molecular chaperone; Psort location: Cytoplasmic, score: 9.65. (202 aa) |
| | glmM | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. (449 aa) |
| | EDS74552.1 | Propanediol utilization protein PduL; Involved in 1,2-propanediol (1,2-PD) degradation by catalyzing the conversion of propanoyl-CoA to propanoyl-phosphate. (190 aa) |
| | map | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (248 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa) |
| | EDS74747.1 | KEGG: mbu:Mbur_1602 0.0043 Fe-S protein, radical SAM family K04035; COG: NOG29880 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (229 aa) |
| | EDS74743.1 | six-Cys-in-45 modification radical SAM protein; KEGG: syg:sync_2368 3.1e-05 arylsulfatase regulator; COG: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); Psort location: Cytoplasmic, score: 8.87. (461 aa) |
| | EDS74726.1 | Radical SAM domain protein; KEGG: reh:H16_A0887 2.6e-21 splB1; DNA repair photolyase K01669; COG: COG1533 DNA repair photolyase; Psort location: Cytoplasmic, score: 8.87. (256 aa) |
| | EDS74721.1 | Cytidine/deoxycytidylate deaminase family protein; KEGG: spi:MGAS10750_Spy1706 1.2e-16 cytidine deaminase K01489; COG: COG0295 Cytidine deaminase; Psort location: Cytoplasmic, score: 8.87. (142 aa) |
| | EDS74699.1 | KEGG: cpf:CPF_2374 3.9e-50 selD; selenide, water dikinase K01008; COG: COG0709 Selenophosphate synthase; Psort location: Cytoplasmic, score: 8.87. (162 aa) |
| | cas3 | CRISPR-associated helicase Cas3; KEGG: afu:AF0071 9.0e-16 ATP-dependent RNA helicase, putative; COG: COG1203 Predicted helicases; Psort location: Cytoplasmic, score: 8.87. (720 aa) |
| | cas4 | CRISPR-associated protein Cas4; COG: COG1468 RecB family exonuclease; Psort location: Cytoplasmic, score: 8.87. (162 aa) |
| | cas1-2 | CRISPR-associated endonuclease Cas1, HMARI/TNEAP subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (335 aa) |
| | cas2-2 | CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (105 aa) |
| | EDS74669.1 | KEGG: spo:SPAPB2B4.01c 4.6e-05 putative N-acetylglucosaminyl phosphatidylinositol deacetylase K03434; COG: KOG3332 N-acetylglucosaminyl phosphatidylinositol de-N-acetylase. (226 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (536 aa) |
| | purF | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (472 aa) |
| | carB-2 | KEGG: bce:BC3886 0. carbamoyl-phosphate synthase large chain K01955; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Psort location: Cytoplasmic, score: 8.87; Belongs to the CarB family. (1060 aa) |
| | EDS74641.1 | 2Fe-2S iron-sulfur cluster-binding domain protein; KEGG: mag:amb2019 7.9e-29 4-hydroxybenzoyl-CoA reductase gamma subunit K04107; COG: COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs; Psort location: Cytoplasmic, score: 8.87. (154 aa) |
| | EDS74640.1 | KEGG: mta:Moth_1960 2.1e-124 aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K00087; COG: COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs; Psort location: CytoplasmicMembrane, score: 9.49. (763 aa) |
| | EDS74818.1 | KEGG: lmf:LMOf2365_0150 3.1e-215 inosine-5'-monophosphate dehydrogenase, putative K00088; COG: COG0516 IMP dehydrogenase/GMP reductase; Psort location: Cytoplasmic, score: 8.87. (504 aa) |
| | miaB | tRNA-i(6)A37 thiotransferase enzyme MiaB; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (481 aa) |
| | EDS74814.1 | Putative metallophosphoesterase; COG: COG1692 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. (259 aa) |
| | fucO | Lactaldehyde reductase; KEGG: cpf:CPF_1046 2.2e-152 fucO; lactaldehyde reductase K00048; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: Cytoplasmic, score: 9.98. (381 aa) |
| | recU | Recombination protein U; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (199 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (214 aa) |
| | EDS74799.1 | DnaD domain protein; KEGG: sha:SH1234 0.0065 polA; DNA polymerase I K02335; COG: COG3935 Putative primosome component and related proteins; Psort location: Cytoplasmic, score: 8.87. (204 aa) |
| | pyk-2 | Pyruvate kinase; KEGG: ssp:SSP1069 2.9e-125 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87. (476 aa) |
| | pheT | KEGG: gka:GK2706 2.5e-151 phenylalanyl-tRNA synthetase beta subunit K01890; COG: COG0073 EMAP domain; Psort location: Cytoplasmic, score: 9.98. (796 aa) |
| | pheS | KEGG: bld:BLi03016 1.4e-123 pheS; phenylalanyl-tRNA synthetase (alpha subunit); RBL00343 K01889; COG: COG0016 Phenylalanyl-tRNA synthetase alpha subunit; Psort location: Cytoplasmic, score: 10.00. (373 aa) |
| | gltX-2 | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (476 aa) |
| | EDS75038.1 | HD domain protein; COG: COG1896 Predicted hydrolases of HD superfamily; Psort location: Cytoplasmic, score: 8.87. (197 aa) |
| | EDS75027.1 | Metallo-beta-lactamase domain protein; KEGG: afu:AF0939 2.2e-07 ribonuclease Z K00784; COG: COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III; Psort location: Cytoplasmic, score: 8.87. (270 aa) |
| | EDS75026.1 | FeoA domain protein; COG: COG1918 Fe2+ transport system protein A; Psort location: Cytoplasmic, score: 8.87. (83 aa) |
| | EDS75024.1 | Hypothetical protein; COG: NOG10982 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (213 aa) |
| | coaX | Pantothenate kinase, type III; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (257 aa) |
| | phnX | Phosphonoacetaldehyde hydrolase; Involved in phosphonate degradation; Belongs to the HAD-like hydrolase superfamily. PhnX family. (259 aa) |
| | EDS75005.1 | Hypothetical protein; KEGG: spk:MGAS9429_Spy0861 2.6e-92 Zn-dependent hydrolase; COG: COG0595 Predicted hydrolase of the metallo-beta-lactamase superfamily; Psort location: Cytoplasmic, score: 8.87. (568 aa) |
| | EDS75001.1 | Metallo-beta-lactamase domain protein; KEGG: fnu:FN1162 2.7e-26 hydroxyacylglutathione hydrolase K01069; COG: COG0491 Zn-dependent hydrolases, including glyoxylases. (202 aa) |
| | hydE | Iron-only hydrogenase maturation rSAM protein HydE; KEGG: bth:BT1835 5.6e-106 biotin synthetase K01012; COG: COG0502 Biotin synthase and related enzymes; Psort location: Cytoplasmic, score: 8.87. (362 aa) |
| | hydG | Iron-only hydrogenase maturation rSAM protein HydG; KEGG: mac:MA0154 2.8e-16 bioB; biotin synthase K01012; COG: COG1060 Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes; Psort location: Cytoplasmic, score: 8.87. (475 aa) |
| | EDS74984.1 | Hypothetical protein; COG: COG1633 Uncharacterized conserved protein. (176 aa) |
| | EDS74980.1 | Hypothetical protein; KEGG: eru:Erum8530 0.0042 icd; isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 8.87. (106 aa) |
| | EDS74979.1 | Radical SAM domain protein; KEGG: dps:DP0065 7.3e-08 pflA; related to pyruvate formate-lyase activating enzyme K04069; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. (353 aa) |
| | EDS74977.1 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (263 aa) |
| | EDS74972.1 | PHP domain protein; KEGG: btl:BALH_4780 3.7e-31 epsC; capsular polysaccharide biosynthesis protein K01104; COG: COG4464 Capsular polysaccharide biosynthesis protein; Psort location: Cytoplasmic, score: 8.87. (246 aa) |
| | EDS74969.1 | Aminopeptidase I zinc metalloprotease (M18); KEGG: cac:CAC0607 3.9e-75 aspartyl aminopeptidase K01269; COG: COG1362 Aspartyl aminopeptidase; Psort location: Cytoplasmic, score: 8.87. (328 aa) |
| | EDS74965.1 | Rubredoxin; KEGG: syn:sll0550 3.3e-46 flavoprotein; COG: COG0426 Uncharacterized flavoproteins; Psort location: Cytoplasmic, score: 8.87. (597 aa) |
| | EDS74963.1 | Bacterial type II secretion system domain protein F; COG: COG1459 Type II secretory pathway, component PulF; Psort location: CytoplasmicMembrane, score: 9.99. (333 aa) |
| | dxs | 1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (624 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (407 aa) |
| | deoB | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. (393 aa) |
| | EDS74933.1 | ACT domain protein; KEGG: nph:NP5006A 6.0e-08 purU; formyltetrahydrofolate deformylase K01433; COG: COG3830 ACT domain-containing protein; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0237 family. (99 aa) |
| | parE | DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 2 subfamily. (642 aa) |
| | tkt | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (658 aa) |
| | EDS74913.1 | Peptidase M16 inactive domain protein; KEGG: bcz:BCZK3546 1.1e-104 insulysin, peptidase family M16 (insulinase) K01408; COG: COG0612 Predicted Zn-dependent peptidases; Psort location: Cytoplasmic, score: 8.87. (426 aa) |
| | EDS74912.1 | Peptidase M16 inactive domain protein; KEGG: bld:BLi01909 1.6e-67 hypothetical protein; COG: COG0612 Predicted Zn-dependent peptidases; Psort location: Cytoplasmic, score: 8.87. (420 aa) |
| | acpS | Holo-[acyl-carrier-protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (110 aa) |
| | rseP | RIP metalloprotease RseP; KEGG: tte:TTE1401 3.4e-51 predicted membrane-associated Zn-dependent protease 1; COG: COG0750 Predicted membrane-associated Zn-dependent proteases 1; Psort location: CytoplasmicMembrane, score: 10.00. (359 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (383 aa) |
| | uppS | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (251 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (690 aa) |
| | rnhB-2 | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (206 aa) |
| | EDS74841.1 | Radical SAM domain protein; COG: COG0641 Arylsulfatase regulator (Fe-S oxidoreductase); Psort location: Cytoplasmic, score: 8.87. (507 aa) |
| | EDS74839.1 | Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score: 8.87. (1253 aa) |
| | purD | KEGG: pca:Pcar_2231 2.7e-106 phosphoribosylamine--glycine ligase K01945; COG: COG0151 Phosphoribosylamine-glycine ligase; Psort location: Cytoplasmic, score: 8.87; Belongs to the GARS family. (416 aa) |
| | EDS75275.1 | SUF system FeS assembly protein, NifU family; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: Cytoplasmic, score: 8.87. (142 aa) |
| | EDS75273.1 | KEGG: baa:BA_4936 1.1e-29 5-formyltetrahydrofolate cyclo-ligase family K01934; COG: COG0212 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (177 aa) |
| | EDS75253.1 | NifU-like protein; COG: COG0694 Thioredoxin-like proteins and domains; Psort location: Cytoplasmic, score: 8.87. (83 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (404 aa) |
| | EDS75249.1 | Radical SAM protein, TIGR01212 family; KEGG: btk:BT9727_4481 2.2e-88 conserved hypothetical protein, possible Fe-S oxidoreductase; COG: COG1242 Predicted Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (313 aa) |
| | EDS75245.1 | KEGG: reh:H16_B1845 2.8e-24 uracil-dna glycosylase K01249; COG: COG1573 Uracil-DNA glycosylase. (192 aa) |
| | EDS75241.1 | Rubrerythrin; KEGG: cpr:CPR_0938 2.0e-22 periplasmic [Fe] hydrogenase 1 K00532; COG: COG1592 Rubrerythrin; Psort location: Cytoplasmic, score: 8.87. (194 aa) |
| | pyrE | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (211 aa) |
| | tagD-2 | KEGG: bcl:ABC3101 5.6e-51 tagD; glycerol-3-phosphate cytidylyltransferase K00980; COG: COG0615 Cytidylyltransferase; Psort location: Cytoplasmic, score: 9.98. (128 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (432 aa) |
| | EDS75208.1 | Riboflavin biosynthesis protein RibD C-terminal domain protein; KEGG: mja:MJ0671 1.4e-15 5-amino-6-(5-phosphoribosylamino)uracil reductase K00082; COG: COG1985 Pyrimidine reductase, riboflavin biosynthesis. (241 aa) |
| | EDS75200.1 | Glycyl-radical enzyme activating protein family protein; KEGG: cno:NT01CX_1221 2.6e-62 pflC; glycerol dehydratase activator K00538; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.98. (298 aa) |
| | tagD | KEGG: bld:BLi03818 1.2e-50 tagD; glycerol-3-phosphate cytidylyltransferase; RBL05030 K00980; COG: COG0615 Cytidylyltransferase; Psort location: Cytoplasmic, score: 9.98. (129 aa) |
| | EDS75164.1 | Alcohol dehydrogenase, iron-dependent; KEGG: ctc:CTC00408 1.1e-104 NADH-dependent butanol dehydrogenase A K00100; COG: COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family; Psort location: Cytoplasmic, score: 9.98. (389 aa) |
| | EDS75155.1 | Hypothetical protein; COG: COG0822 NifU homolog involved in Fe-S cluster formation; Psort location: Cytoplasmic, score: 8.87. (230 aa) |
| | eno-2 | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (429 aa) |
| | EDS75153.1 | Iron dependent repressor DNA binding domain protein; COG: COG1321 Mn-dependent transcriptional regulator; Psort location: Cytoplasmic, score: 9.98. (120 aa) |
| | EDS75145.1 | Creatinase; KEGG: cpr:CPR_2506 5.8e-88 metallopeptidase, family M24 K01271; COG: COG0006 Xaa-Pro aminopeptidase; Psort location: Cytoplasmic, score: 8.87. (357 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa) |
| | murE-2 | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (454 aa) |
| | EDS75105.1 | KEGG: ctc:CTC01806 2.7e-209 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: COG1410 Methionine synthase I, cobalamin-binding domain; Psort location: Cytoplasmic, score: 8.87. (785 aa) |
| | EDS75104.1 | Vitamin B12 dependent methionine synthase, activation domain protein; KEGG: ctc:CTC01807 5.9e-24 putative 5-methyltetrahydrofolate--homocysteine methyltransferase K00548; COG: NOG21937 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (210 aa) |
| | EDS75098.1 | Cytidine and deoxycytidylate deaminase zinc-binding region; KEGG: fnu:FN1902 5.3e-55 deoxycytidylate deaminase K01493; COG: COG2131 Deoxycytidylate deaminase; Psort location: Cytoplasmic, score: 8.87. (154 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (259 aa) |
| | EDS75081.1 | KEGG: spd:SPD_1659 1.3e-12 phosphodiesterase, MJ0936 family protein; COG: COG0622 Predicted phosphoesterase; Psort location: Cytoplasmic, score: 8.87. (154 aa) |
| | ysxC | Ribosome biogenesis GTP-binding protein YsxC; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (199 aa) |
| | EDS75065.1 | COG: COG2003 DNA repair proteins; Psort location: Cytoplasmic, score: 8.87; Belongs to the UPF0758 family. (225 aa) |
| | cgtA | Obg family GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (428 aa) |
| | EDS75473.1 | KEGG: bth:BT4678 3.0e-100 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score: 8.87. (404 aa) |
| | EDS75472.1 | Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (363 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (374 aa) |
| | EDS75466.1 | Hypothetical protein; COG: COG1879 ABC-type sugar transport system, periplasmic component. (314 aa) |
| | EDS75438.1 | Glycyl-radical enzyme activating protein family protein; KEGG: tko:TK0290 3.5e-58 pyruvate-formate lyase-activating enzyme K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.98. (313 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (226 aa) |
| | alaS | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (869 aa) |
| | EDS75393.1 | Putative phosphoribosylamine--glycine ligase; KEGG: ctc:CTC01706 1.1e-40 putative carbamoyl-phosphate synthase large chain K01954; COG: COG0439 Biotin carboxylase; Psort location: Cytoplasmic, score: 8.87. (413 aa) |
| | EDS75366.1 | Hypothetical protein. (68 aa) |
| | EDS75354.1 | Iron dependent repressor DNA binding domain protein; KEGG: crp:CRP_036 0.0076 putative tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase K00566; COG: COG1321 Mn-dependent transcriptional regulator; Psort location: Cytoplasmic, score: 9.98. (137 aa) |
| | pnp | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (710 aa) |
| | pfkA-2 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (371 aa) |
| | EDS75339.1 | FeoA domain protein; COG: COG1918 Fe2+ transport system protein A. (70 aa) |
| | EDS75338.1 | FeoA domain protein; KEGG: bsu:BG10819 0.0097 atpA; ATP synthase alpha chain K02111; COG: COG1918 Fe2+ transport system protein A; Psort location: Cytoplasmic, score: 8.87. (72 aa) |
| | EDS75334.1 | Heavy metal-associated domain protein; KEGG: tde:TDE0008 7.3e-09 copper-translocating P-type ATPase K01533; COG: COG2217 Cation transport ATPase; Psort location: Cytoplasmic, score: 8.87. (119 aa) |
| | EDS75314.1 | Copper-exporting ATPase; KEGG: cpf:CPF_0534 2.0e-185 copper-translocating P-type ATPase K01533; COG: COG2217 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00. (812 aa) |
| | EDS75313.1 | COG: COG1937 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score: 8.87. (83 aa) |
| | eno | Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa) |
| | EDS75636.1 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (87 aa) |
| | EDS75635.1 | Hypothetical protein; Psort location: Cytoplasmic, score: 8.87. (240 aa) |
| | gpmI | 2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (505 aa) |
| | cutC | CutC family protein; Participates in the control of copper homeostasis. Belongs to the CutC family. (245 aa) |
| | EDS75574.1 | Heavy metal-associated domain protein; KEGG: fnu:FN0259 4.5e-10 zinc-transporting ATPase K01534; COG: COG2608 Copper chaperone. (77 aa) |
| | cadA | Cadmium-exporting ATPase; KEGG: btk:BT9727_0506 3.5e-193 cation-transporting ATPase, P-type; COG: COG2217 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 10.00. (622 aa) |
| | EDS75552.1 | Hypothetical protein; KEGG: mxa:MXAN_0764 3.3e-18 peptidase, M24 (methionyl aminopeptidase 1) family K01423; COG: NOG08884 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (410 aa) |
| | pepT | Peptidase T; Cleaves the N-terminal amino acid of tripeptides. Belongs to the peptidase M20B family. (402 aa) |
| | pflA | Pyruvate formate-lyase 1-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (249 aa) |
| | murE | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (483 aa) |
| | yqeV | tRNA methylthiotransferase YqeV; KEGG: bce:BC4308 7.7e-125 Fe-S oxidoreductase; COG: COG0621 2-methylthioadenine synthetase; Psort location: Cytoplasmic, score: 8.87. (428 aa) |
| | sodC | KEGG: ctc:CTC00590 6.5e-25 superoxide dismutase (Cu-Zn) K04565; COG: COG2032 Cu/Zn superoxide dismutase. (161 aa) |
| | thiE | Thiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (212 aa) |
| | EDS75528.1 | Rubredoxin; KEGG: cpr:CPR_0938 9.4e-10 periplasmic [Fe] hydrogenase 1 K00532; COG: COG1592 Rubrerythrin; Psort location: Cytoplasmic, score: 8.87. (186 aa) |
| | rpe | KEGG: mcp:MCAP_0260 5.8e-49 rpe; ribulose-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score: 8.87. (213 aa) |
| | rsgA | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (285 aa) |
| | rlmN | 23S rRNA m2A2503 methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs; Belongs to the radical SAM superfamily. RlmN family. (342 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (746 aa) |
| | EDS75509.1 | Conserved hypothetical protein, YfiH family; COG: COG1496 Uncharacterized conserved protein; Belongs to the multicopper oxidase YfiH/RL5 family. (251 aa) |
| | nnrD | YjeF domain protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...] (494 aa) |
| | EDS75504.1 | KEGG: spd:SPD_1659 8.1e-11 phosphodiesterase, MJ0936 family protein; COG: COG0622 Predicted phosphoesterase. (160 aa) |
| | EDS75498.1 | E1-E2 ATPase; KEGG: btl:BALH_0536 2.9e-48 cation-transporting ATPase, P-type; COG: COG2217 Cation transport ATPase; Psort location: CytoplasmicMembrane, score: 9.99. (658 aa) |
| | EDS75494.1 | Thermophilic metalloprotease (M29); KEGG: cpr:CPR_1965 3.3e-117 aminopeptidase K01269; COG: COG2309 Leucyl aminopeptidase (aminopeptidase T). (419 aa) |
| | nadK | NAD(+)/NADH kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (260 aa) |
| | EDS75968.1 | M42 glutamyl aminopeptidase; KEGG: btk:BT9727_0795 6.8e-78 yhfE; glucanase; deblocking aminopeptidase K01269; COG: COG1363 Cellulase M and related proteins. (339 aa) |
| | cas2 | CRISPR-associated endoribonuclease Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (107 aa) |
| | cas1 | CRISPR-associated endonuclease Cas1, NMENI subtype; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (297 aa) |
| | csn1 | CRISPR-associated protein, Csn1 family; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans- encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this [...] (1116 aa) |
| | EDS75950.1 | ATP-grasp domain protein; KEGG: cpe:CPE0819 2.0e-05 ddlB; D-alanine-D-alanine ligase K01921; COG: NOG08747 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (401 aa) |
| | EDS75948.1 | Hypothetical protein; KEGG: aae:aq_742 2.3e-05 purD; phosphoribosylamine-glycine ligase K01945; COG: NOG08747 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (399 aa) |
| | EDS75940.1 | Hypothetical protein; COG: NOG13832 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87; Belongs to the arginase family. (253 aa) |
| | rnj | Hypothetical protein; An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (590 aa) |
| | hflX | GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (408 aa) |
| | EDS75906.1 | Rubredoxin; KEGG: cpr:CPR_0938 4.3e-36 periplasmic [Fe] hydrogenase 1 K00532; COG: COG1592 Rubrerythrin. (194 aa) |
| | rdgB | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (195 aa) |
| | bioB | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (319 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (216 aa) |
| | EDS75835.1 | Putative mannose-6-phosphate isomerase, class I; KEGG: bth:BT0373 3.0e-20 mannose-6-phosphate isomerase K01809; COG: COG1482 Phosphomannose isomerase; Psort location: Cytoplasmic, score: 8.87. (568 aa) |
| | EDS75825.1 | Sugar-binding domain protein; KEGG: msm:MSMEG_3095 4.0e-25 D-ribose-binding periplasmic protein; COG: COG1879 ABC-type sugar transport system, periplasmic component; Psort location: Cytoplasmic, score: 8.87. (288 aa) |
| | EDS75819.1 | ImpB/MucB/SamB family protein; KEGG: btl:BALH_p0040 1.5e-41 uvrX; DNA-damage repair protein (DNA polymerase IV) K00961; COG: COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair; Psort location: Cytoplasmic, score: 8.87. (506 aa) |
| | EDS75817.1 | Class II glutamine amidotransferase; KEGG: syn:sll1502 0. gltB; NADH-dependent glutamate synthase large subunit K00268; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score: 8.87. (1511 aa) |
| | EDS75796.1 | COG: COG2364 Predicted membrane protein; Psort location: CytoplasmicMembrane, score: 9.99. (217 aa) |
| | EDS75777.1 | Putative HAD hydrolase, family IB; KEGG: ctc:CTC01739 1.4e-29 phosphoserine phosphatase K01079; COG: COG0560 Phosphoserine phosphatase; Psort location: Cytoplasmic, score: 8.87. (207 aa) |
| | EDS75746.1 | Creatinase; KEGG: fnu:FN0453 5.4e-140 Xaa-Pro aminopeptidase K01262; COG: COG0006 Xaa-Pro aminopeptidase; Psort location: Cytoplasmic, score: 8.87. (583 aa) |
| | nrdG | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (166 aa) |
| | EDS75741.1 | Radical SAM domain protein; KEGG: bha:BH2952 1.3e-104 Mg-protoporphyrin IX monomethyl ester oxidative cyclase K04034; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (544 aa) |
| | EDS75738.1 | Hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type; KEGG: ctc:CTC02562 9.2e-90 fumarate hydratase subunit A K01677; COG: COG1951 Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain; Psort location: Cytoplasmic, score: 8.87. (280 aa) |
| | EDS75727.1 | SNF2 family N-terminal domain protein; KEGG: lwe:lwe1660 2.5e-119 DNA/RNA helicase protein K01529; COG: COG0553 Superfamily II DNA/RNA helicases, SNF2 family; Psort location: Cytoplasmic, score: 8.87. (1064 aa) |
| | hcp | Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O. (525 aa) |
| | EDS75667.1 | Iron transport-associated domain protein. (270 aa) |
| | EDS75666.1 | KEGG: chy:CHY_0128 4.3e-76 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87. (282 aa) |
| | nagA | KEGG: efa:EF3044 3.0e-75 nagA-2; N-acetylglucosamine-6-phosphate deacetylase K01443; COG: COG1820 N-acetylglucosamine-6-phosphate deacetylase. (383 aa) |
| | carB | KEGG: sat:SYN_02589 0. carbamoyl-phosphate synthase large chain K01954; COG: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Belongs to the CarB family. (1072 aa) |
| | gltX | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (479 aa) |
| | ispF | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (160 aa) |
| | pyk | Pyruvate kinase; KEGG: oih:OB2171 3.5e-129 pykA; pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score: 8.87. (478 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (319 aa) |
| | mutM | DNA-formamidopyrimidine glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (270 aa) |
| | fdx | Ferredoxin; KEGG: mja:MJ1167 7.9e-05 fwdG; formylmethanofuran dehydrogenase, subunit G (tungsten) K00205; COG: COG1141 Ferredoxin; Psort location: Cytoplasmic, score: 8.87. (58 aa) |
| | EDS75995.1 | Transcriptional regulator, Sir2 family; KEGG: tte:TTE1570 7.9e-13 sir2; NAD-dependent protein deacetylase, Sir2 family K01463; COG: COG0846 NAD-dependent protein deacetylases, SIR2 family; Psort location: Cytoplasmic, score: 8.87. (198 aa) |
| | EDS76122.1 | Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: gka:GK3297 1.2e-151 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score: 8.87. (564 aa) |
| | EDS76100.1 | dUTP diphosphatase; COG: COG4508 Uncharacterized protein conserved in bacteria. (152 aa) |
| | luxS | S-ribosylhomocysteinase LuxS; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family. (148 aa) |
| | EDS76091.1 | PHP domain protein; KEGG: vfi:VFA0065 2.6e-30 DNA polymerase beta K04477; COG: COG1387 Histidinol phosphatase and related hydrolases of the PHP family. (249 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (343 aa) |
| | EDS76064.1 | Radical SAM domain protein; KEGG: pca:Pcar_1695 3.7e-31 deoxyribonuclease, TatD family K03424; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score: 8.87. (214 aa) |
| | nifJ | KEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score: 8.87. (1172 aa) |
| | licA | Lichenan-specific phosphotransferase enzyme IIA component; KEGG: bca:BCE_5319 5.0e-27 celC; PTS system, cellobiose-specific IIA component K02759; COG: COG1447 Phosphotransferase system cellobiose-specific component IIA; Psort location: Cytoplasmic, score: 9.98. (102 aa) |
| | rpoC | DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1224 aa) |
| | EDS74093.1 | Putative superoxide reductase; KEGG: pca:Pcar_2347 1.7e-24 desulfoferrodoxin K05919; COG: COG2033 Desulfoferrodoxin; Psort location: Cytoplasmic, score: 8.87. (127 aa) |
| | ilvB | KEGG: chy:CHY_0517 2.1e-163 ilvB1; acetolactate synthase, large subunit, biosynthetic type K01652; COG: COG0028 Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]; Psort location: Cytoplasmic, score: 8.87. (559 aa) |
| | ilvD | KEGG: sat:SYN_01708 4.0e-199 dihydroxy-acid dehydratase K01687; COG: COG0129 Dihydroxyacid dehydratase/phosphogluconate dehydratase; Psort location: Cytoplasmic, score: 8.87; Belongs to the IlvD/Edd family. (558 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (360 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (424 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa) |
| | ddl | D-ala D-ala ligase N-terminal domain protein; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (346 aa) |
| | map-2 | Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (277 aa) |
| | ppk1 | Polyphosphate kinase 1; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (676 aa) |
| | EDS74054.1 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (355 aa) |
| | manA | KEGG: cno:NT01CX_1588 2.0e-62 manA; mannose-6-phosphate isomerase, class I K01809; COG: COG1482 Phosphomannose isomerase; Psort location: Cytoplasmic, score: 8.87. (321 aa) |
| | EDS74043.1 | Hypothetical protein; KEGG: mma:MM1058 4.2e-14 5-amino-6-(5-phosphoribosylamino)uracil reductase K00082; COG: COG1985 Pyrimidine reductase, riboflavin biosynthesis. (245 aa) |
| | lysS | lysine--tRNA ligase; KEGG: gka:GK0074 3.2e-167 lysyl-tRNA synthetase (lysine--tRNA ligase) K04567; COG: COG1190 Lysyl-tRNA synthetase (class II); Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. (496 aa) |
| | trmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (444 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (641 aa) |
| | tadA | Cytidine and deoxycytidylate deaminase zinc-binding region; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (148 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (197 aa) |
| | EDS73961.1 | Putative sporulation transcription factor Spo0A; KEGG: ava:Ava_B0029 7.3e-05 two component transcriptional regulator, LuxR family; COG: COG0784 FOG: CheY-like receiver. (247 aa) |
| | EDS73960.1 | Putative sporulation transcription factor Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (271 aa) |
| | rfbA-2 | Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa) |
| | EDS73923.1 | Arylsulfatase; KEGG: eba:ebA3535 2.1e-44 mdoB; phosphoglycerol transferase I K01002; COG: COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily; Psort location: CytoplasmicMembrane, score: 9.75. (496 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (207 aa) |
| | speB | Agmatinase; KEGG: cpe:CPE0551 6.9e-101 speB; probable agmatinase K01480; COG: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase, arginase family; Psort location: Cytoplasmic, score: 8.87; Belongs to the arginase family. (286 aa) |
| | EDS73872.1 | tRNA nucleotidyltransferase/poly(A) polymerase family protein; KEGG: tdn:Tmden_0005 4.2e-46 polynucleotide adenylyltransferase region K00974; COG: COG0617 tRNA nucleotidyltransferase/poly(A) polymerase; Psort location: Cytoplasmic, score: 8.87. (451 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (940 aa) |
| | hprK | HPr(Ser) kinase/phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable car [...] (311 aa) |
| | EDS73862.1 | Glycyl-radical enzyme activating protein family protein; KEGG: ctc:CTC00937 5.8e-65 pyruvate formate-lyase K04069; COG: COG1180 Pyruvate-formate lyase-activating enzyme; Psort location: Cytoplasmic, score: 9.65. (298 aa) |
| | glmU | UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (467 aa) |
| | prs | Ribose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (318 aa) |
| | dut | dUTP diphosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (170 aa) |
| | nrdG-2 | Anaerobic ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (170 aa) |
| | EDS73826.1 | DHHA1 domain protein; Has phosphodiesterase (PDE) activity against cyclic-di-AMP (c-di-AMP); Belongs to the GdpP/PdeA phosphodiesterase family. (662 aa) |
| | tdk | Thymidine kinase; KEGG: bha:BH3779 1.8e-63 tdk; thymidine kinase K00857; COG: COG1435 Thymidine kinase; Psort location: Cytoplasmic, score: 8.87. (196 aa) |
| | hpt | KEGG: spn:SP_0012 2.4e-50 hypoxanthine-guanine phosphoribosyltransferase K00760; COG: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (176 aa) |
| | hflB | ATP-dependent metallopeptidase HflB; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (648 aa) |
| | EDS73803.1 | LPXTG-motif cell wall anchor domain protein; KEGG: ath:At5g13690 2.7e-88 MSH12.16; alpha-N-acetylglucosaminidase K01205; COG: NOG36584 non supervised orthologous group; Psort location: Extracellular, score: 9.97. (1990 aa) |
| | fba | KEGG: cpf:CPF_1557 3.4e-115 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score: 8.87. (288 aa) |
| | EDS73797.1 | Methyltransferase domain protein; KEGG: spt:SPA1038 1.0e-44 rrmA; rRNA guanine-N1-methyltransferase K00563; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score: 8.87. (271 aa) |
| | EDS73793.1 | F5/8 type C domain protein; KEGG: ddi:DDB0184151 5.8e-67 hypothetical protein K01205; COG: NOG36584 non supervised orthologous group; Psort location: Extracellular, score: 9.55. (1762 aa) |
| | EDS73764.1 | VanZ-like protein; COG: COG5652 Predicted integral membrane protein. (142 aa) |
| | EDS73753.1 | M42 glutamyl aminopeptidase; KEGG: fnu:FN0999 3.9e-66 deblocking aminopeptidase K01269; COG: COG1363 Cellulase M and related proteins; Psort location: Cytoplasmic, score: 8.87. (346 aa) |
| | EDS73752.1 | KEGG: cno:NT01CX_0140 1.6e-202 aconitate hydratase K01680; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score: 8.87. (647 aa) |
| | EDS73751.1 | Putative isocitrate dehydrogenase, NAD-dependent; KEGG: cac:CAC0972 2.9e-93 citC; isocitrate dehydrogenase K00030; COG: COG0473 Isocitrate/isopropylmalate dehydrogenase; Psort location: Cytoplasmic, score: 9.98. (331 aa) |
| | EDS73742.1 | KEGG: cno:NT01CX_1542 4.6e-79 alcohol dehydrogenase, iron-containing K00100; COG: COG1979 Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family; Psort location: Cytoplasmic, score: 9.65. (389 aa) |
| | EDS73731.1 | Hypothetical protein; KEGG: mta:Moth_1016 0.0043 catalase K00429; COG: COG1633 Uncharacterized conserved protein. (149 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa) |
| | EDS73699.1 | 4Fe-4S binding domain protein; KEGG: mmp:MMP1692 4.4e-05 vhuB; polyferredoxin, associated with F420-non-reducing hydrogenase; COG: NOG11133 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (254 aa) |
| | EDS73692.1 | KEGG: sfu:Sfum_0268 3.2e-142 amidophosphoribosyltransferase K00764; COG: COG0034 Glutamine phosphoribosylpyrophosphate amidotransferase; Psort location: Cytoplasmic, score: 8.87; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (469 aa) |
| | EDS73687.1 | Hypothetical protein; KEGG: mmy:MSC_0769 0.0030 pcrA; ATP-dependent DNA helicase K03657; COG: COG3210 Large exoproteins involved in heme utilization or adhesion; Psort location: Cytoplasmic, score: 8.87. (489 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | EDS74457.1 | Alcohol dehydrogenase, iron-dependent; KEGG: cpf:CPF_1465 2.7e-131 adh1; NADPH-dependent butanol dehydrogenase K00100; COG: COG1454 Alcohol dehydrogenase, class IV; Psort location: Cytoplasmic, score: 9.98. (405 aa) |
| | EDS74453.1 | Respiratory-chain NADH dehydrogenase 24 Kd subunit; KEGG: bth:BT0123 3.1e-34 NADH-ubiquinone oxidoreductase subunit K00334; COG: COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit; Psort location: Cytoplasmic, score: 9.98. (163 aa) |
| | EDS74450.1 | 4Fe-4S binding domain protein; KEGG: cno:NT01CX_1006 5.5e-16 hydrogenase K00532; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87. (386 aa) |
| | EDS74446.1 | Hypothetical protein; KEGG: mta:Moth_1718 1.6e-19 NADH dehydrogenase (quinone) K00335; COG: COG3411 Ferredoxin; Psort location: Cytoplasmic, score: 8.87. (122 aa) |
| | EDS74445.1 | 4Fe-4S binding domain protein; KEGG: tte:TTE0893 7.2e-225 nuoF; NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit K00335; COG: COG1894 NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; Psort location: Cytoplasmic, score: 9.98. (599 aa) |
| | EDS74444.1 | Hydrogenase, Fe-only; KEGG: tte:TTE0894 1.4e-180 nuoG; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) K00336; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87. (582 aa) |
| | folC-2 | Bifunctional protein FolC; KEGG: lmo:lmo1551 1.3e-60 folC; folylpolyglutamate synthase K01930; COG: COG0285 Folylpolyglutamate synthase; Psort location: Cytoplasmic, score: 8.87. (519 aa) |
| | EDS74410.1 | Glyoxalase family protein; KEGG: bth:BT1580 1.0e-42 lactoylglutathione lyase K01759; COG: COG0346 Lactoylglutathione lyase and related lyases; Psort location: Cytoplasmic, score: 8.87. (122 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (929 aa) |
| | EDS74371.1 | Hypothetical protein; KEGG: lic:LIC13172 3.7e-07 adenosine deaminase K01489; COG: NOG34388 non supervised orthologous group; Psort location: Cytoplasmic, score: 8.87. (928 aa) |
| | EDS74345.1 | HpcH/HpaI aldolase/citrate lyase family protein; KEGG: sto:ST1786 0.0018 citrate lyase beta chain K01644; Psort location: Cytoplasmic, score: 8.87; Belongs to the HpcH/HpaI aldolase family. (290 aa) |
| | mraY | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (329 aa) |
| | EDS74316.1 | Methionine synthase, vitamin-B12 independent; KEGG: lsl:LSL_0129 5.1e-112 metE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase K00549; COG: COG0620 Methionine synthase II (cobalamin-independent); Psort location: Cytoplasmic, score: 8.87. (372 aa) |
| | pepF | Oligoendopeptidase F; KEGG: tte:TTE1010 4.9e-123 Oligoendopeptidase F K08602; COG: COG1164 Oligoendopeptidase F; Psort location: Cytoplasmic, score: 9.98. (591 aa) |
| | ispG | 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (351 aa) |
| | nfo | Apurinic endonuclease (APN1); Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (286 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (303 aa) |
| | EDS74282.1 | Dinuclear metal center protein, YbgI family; COG: COG0327 Uncharacterized conserved protein; Psort location: Cytoplasmic, score: 8.87. (249 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (583 aa) |
| | EDS74276.1 | Putative radical SAM protein YgiQ; KEGG: fnu:FN0734 8.1e-130 Fe-S oxidoreductase; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score: 8.87. (637 aa) |
| | recO | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (250 aa) |
| | cdd | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (138 aa) |
| | ybeY | Translation metalloprotein YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (152 aa) |
| | EDS74246.1 | Hypothetical protein; KEGG: reu:Reut_B4409 6.3e-27 catalase K07217; COG: COG3546 Mn-containing catalase; Psort location: Cytoplasmic, score: 8.87. (203 aa) |
| | EDS74234.1 | PHP domain protein; KEGG: cno:NT01CX_1524 2.1e-28 CpsB protein K01104; COG: COG4464 Capsular polysaccharide biosynthesis protein; Psort location: Cytoplasmic, score: 8.87. (253 aa) |
| | EDS74223.1 | 4Fe-4S binding domain protein; KEGG: mka:MK0930 1.7e-05 coenzyme F420-reducing hydrogenase, gamma subunit K00439; COG: COG1145 Ferredoxin; Psort location: Cytoplasmic, score: 8.87. (253 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (165 aa) |
| | aroB | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (352 aa) |
| | thrS | threonine--tRNA ligase; KEGG: fnu:FN0611 1.7e-182 threonyl-tRNA synthetase K01868; COG: COG0441 Threonyl-tRNA synthetase; Psort location: Cytoplasmic, score: 10.00; Belongs to the class-II aminoacyl-tRNA synthetase family. (606 aa) |
| | EDS74200.1 | 4Fe-4S binding domain protein; KEGG: cno:NT01CX_0464 3.1e-98 Fe-hydrogenase large subunit family protein K00532; COG: COG4624 Iron only hydrogenase large subunit, C-terminal domain; Psort location: Cytoplasmic, score: 8.87. (507 aa) |
| | tsaD | Putative glycoprotease GCP; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (344 aa) |
| | ackA-2 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (396 aa) |
| | def-2 | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (136 aa) |
| | EDS74149.1 | COG: COG4851 Protein involved in sex pheromone biosynthesis. (357 aa) |
| | ligA | DNA ligase (NAD+); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (682 aa) |
| | pyrK | Oxidoreductase NAD-binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (251 aa) |
| | pyrC | Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (422 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (189 aa) |
| | pfp | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (412 aa) |
| | EDS74119.1 | Putative dipeptidase; KEGG: lin:lin1661 5.6e-90 similar to Xaa-His dipeptidase K01439; COG: COG0624 Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases; Psort location: Cytoplasmic, score: 8.87. (455 aa) |
| | ptsP | Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (576 aa) |
| | EDS74629.1 | Alcohol dehydrogenase, iron-dependent; KEGG: msu:MS2190 0. eutG; alcohol dehydrogenase IV K00001:K04072; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score: 9.98; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (882 aa) |
