STRINGSTRING
EDP12382.1 EDP12382.1 serC serC pdxB pdxB EDP12329.1 EDP12329.1 EDP12339.1 EDP12339.1 EDP12340.1 EDP12340.1 EDP12345.1 EDP12345.1 EDP12353.1 EDP12353.1 EDP12360.1 EDP12360.1 EDP12361.1 EDP12361.1 EDP12300.1 EDP12300.1 EDP12213.1 EDP12213.1 EDP12275.1 EDP12275.1 EDP12278.1 EDP12278.1 EDP12118.1 EDP12118.1 EDP12129.1 EDP12129.1 EDP12136.1 EDP12136.1 pfkA pfkA pyk pyk EDP12152.1 EDP12152.1 EDP12160.1 EDP12160.1 EDP12162.1 EDP12162.1 EDP12163.1 EDP12163.1 pdxB-2 pdxB-2 dapA dapA EDP12191.1 EDP12191.1 EDP12192.1 EDP12192.1 rex rex EDP12080.1 EDP12080.1 cscA cscA EDP12048.1 EDP12048.1 EDP11823.1 EDP11823.1 EDP11832.1 EDP11832.1 EDP11856.1 EDP11856.1 EDP11911.1 EDP11911.1 EDP11924.1 EDP11924.1 EDP11931.1 EDP11931.1 EDP11936.1 EDP11936.1 EDP11937.1 EDP11937.1 EDP11949.1 EDP11949.1 EDP11973.1 EDP11973.1 EDP11979.1 EDP11979.1 map map adk adk EDP12027.1 EDP12027.1 EDP11421.1 EDP11421.1 fba fba purD purD EDP11451.1 EDP11451.1 EDP11455.1 EDP11455.1 EDP11457.1 EDP11457.1 pfp pfp EDP11488.1 EDP11488.1 EDP11489.1 EDP11489.1 EDP11495.1 EDP11495.1 EDP11496.1 EDP11496.1 EDP11499.1 EDP11499.1 EDP11503.1 EDP11503.1 EDP11510.1 EDP11510.1 ispE ispE EDP11515.1 EDP11515.1 EDP11525.1 EDP11525.1 metK metK EDP11539.1 EDP11539.1 EDP11540.1 EDP11540.1 EDP11541.1 EDP11541.1 pdxB-3 pdxB-3 aroB aroB aroC aroC aroF aroF aroA aroA EDP11558.1 EDP11558.1 EDP11566.1 EDP11566.1 miaA miaA EDP11583.1 EDP11583.1 rfbD rfbD rfbB rfbB rfbC rfbC rfbA rfbA galU galU glyA glyA EDP11658.1 EDP11658.1 EDP11659.1 EDP11659.1 purE purE EDP11683.1 EDP11683.1 purF purF purM purM purN purN purH purH EDP11696.1 EDP11696.1 EDP11698.1 EDP11698.1 cscA-2 cscA-2 EDP11742.1 EDP11742.1 map-2 map-2 EDP11761.1 EDP11761.1 prs prs rpiB rpiB gpmI gpmI ispF ispF EDP11789.1 EDP11789.1 EDP11808.1 EDP11808.1 EDP11811.1 EDP11811.1 plsY plsY ispH ispH ispG ispG dapA-2 dapA-2 purC purC EDP11196.1 EDP11196.1 dxs dxs EDP11204.1 EDP11204.1 EDP11208.1 EDP11208.1 ribF ribF EDP11217.1 EDP11217.1 gltA gltA aroD aroD aroK aroK aroF-2 aroF-2 EDP11243.1 EDP11243.1 EDP11253.1 EDP11253.1 dxr dxr cdsA cdsA uppS uppS trmD trmD EDP11403.1 EDP11403.1 EDP11413.1 EDP11413.1 EDP11022.1 EDP11022.1 hisZ hisZ hisG hisG hisD hisD EDP11040.1 EDP11040.1 hisB hisB hisH hisH hisA hisA hisF hisF hisI hisI hisE hisE EDP11053.1 EDP11053.1 EDP11054.1 EDP11054.1 EDP11056.1 EDP11056.1 malQ malQ EDP10819.1 EDP10819.1 EDP10820.1 EDP10820.1 EDP10843.1 EDP10843.1 ilvA ilvA rpe rpe EDP10863.1 EDP10863.1 EDP10867.1 EDP10867.1 EDP10871.1 EDP10871.1 EDP10878.1 EDP10878.1 EDP10885.1 EDP10885.1 EDP10887.1 EDP10887.1 EDP10990.1 EDP10990.1 pgi pgi ppdK ppdK EDP10413.1 EDP10413.1 proC proC EDP10439.1 EDP10439.1 EDP10457.1 EDP10457.1 EDP10460.1 EDP10460.1 ldh ldh EDP10471.1 EDP10471.1 EDP10474.1 EDP10474.1 EDP10485.1 EDP10485.1 EDP10488.1 EDP10488.1 EDP10493.1 EDP10493.1 nifJ nifJ EDP10506.1 EDP10506.1 EDP10510.1 EDP10510.1 proA proA EDP10519.1 EDP10519.1 EDP10527.1 EDP10527.1 EDP10536.1 EDP10536.1 cysE cysE EDP10555.1 EDP10555.1 EDP10567.1 EDP10567.1 EDP10568.1 EDP10568.1 EDP10569.1 EDP10569.1 grpE grpE EDP10587.1 EDP10587.1 deoD deoD EDP10601.1 EDP10601.1 EDP10634.1 EDP10634.1 asnA asnA EDP10671.1 EDP10671.1 EDP10681.1 EDP10681.1 EDP10685.1 EDP10685.1 EDP10703.1 EDP10703.1 tig tig EDP10724.1 EDP10724.1 xpt xpt EDP10744.1 EDP10744.1 EDP10745.1 EDP10745.1 EDP10746.1 EDP10746.1 EDP10752.1 EDP10752.1 EDP10771.1 EDP10771.1 EDP10783.1 EDP10783.1 EDP10785.1 EDP10785.1 EDP10794.1 EDP10794.1 EDP10064.1 EDP10064.1 ndk ndk tpiA tpiA pgk pgk EDP10096.1 EDP10096.1 glgA glgA glgD glgD glgC glgC ispD ispD lysA lysA dapA-3 dapA-3 dapB dapB EDP10147.1 EDP10147.1 EDP10165.1 EDP10165.1 tilS tilS hpt hpt EDP10182.1 EDP10182.1 EDP10206.1 EDP10206.1 EDP10208.1 EDP10208.1 glgB glgB gpsA gpsA glgP glgP EDP10242.1 EDP10242.1 pulA pulA EDP10255.1 EDP10255.1 gap gap eno eno EDP10320.1 EDP10320.1 EDP10330.1 EDP10330.1 EDP10344.1 EDP10344.1 EDP10347.1 EDP10347.1 asd asd EDP10350.1 EDP10350.1 EDP10351.1 EDP10351.1 thrC thrC thrB thrB EDP10354.1 EDP10354.1 maf maf EDP10361.1 EDP10361.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
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EDP12382.1LPXTG-motif cell wall anchor domain protein; Psort location: Cellwall, score:9.98. (495 aa)
serCPhosphoserine transaminase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (379 aa)
pdxB4-phosphoerythronate dehydrogenase; KEGG: btk:BT9727_3022 1.0e-106 serA; D-3-phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (390 aa)
EDP12329.1Aminotransferase, class I/II; KEGG: bce:BC2896 2.8e-95 aspartate aminotransferase; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score:8.87. (381 aa)
EDP12339.1Transketolase, thiamine diphosphate binding domain protein; KEGG: cno:NT01CX_1267 3.4e-92 transketolase, N-terminal subunit K00615; COG: COG3959 Transketolase, N-terminal subunit; Psort location: Cytoplasmic, score:8.87. (275 aa)
EDP12340.1Transketolase, pyridine binding domain protein; KEGG: cno:NT01CX_1268 2.8e-104 transketolase, C-terminal subunit K00615; COG: COG3958 Transketolase, C-terminal subunit. (309 aa)
EDP12345.1ACT domain protein; KEGG: nph:NP5006A 0.0039 purU; formyltetrahydrofolate deformylase K01433; COG: COG3830 ACT domain-containing protein; Belongs to the UPF0237 family. (91 aa)
EDP12353.1Nuclease-like protein; KEGG: efa:EF_B0045 2.5e-25 nuc-2; thermonuclease precursor K01174; COG: COG1525 Micrococcal nuclease (thermonuclease) homologs; Psort location: Extracellular, score:10.00. (207 aa)
EDP12360.1KEGG: sak:SAK_0393 7.8e-21 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (266 aa)
EDP12361.1Aldose 1-epimerase; KEGG: ldb:Ldb1268 2.6e-30 putative mutarotase K01785; COG: COG2017 Galactose mutarotase and related enzymes; Psort location: Cytoplasmic, score:8.87. (287 aa)
EDP12300.1Transcriptional regulator, Spx/MgsR family; KEGG: lsl:LSL_1330 5.2e-32 arsC; arsenate reductase; COG: COG1393 Arsenate reductase and related proteins, glutaredoxin family; Psort location: Cytoplasmic, score:8.87; Belongs to the ArsC family. (145 aa)
EDP12213.1Hypothetical protein; Psort location: Extracellular, score:8.82. (40 aa)
EDP12275.1KEGG: cpe:CPE1070 1.4e-45 fabG; 3-oxoacyl-[acyl-carrier-protein] reductase K00059; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score:9.98; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (249 aa)
EDP12278.1HAD hydrolase, family IIB; KEGG: aha:AHA_0482 0.00010 phosphatase YidA K01112; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (252 aa)
EDP12118.1KEGG: sak:SAK_0393 4.1e-08 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (287 aa)
EDP12129.1EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.87. (279 aa)
EDP12136.1Hypothetical protein; KEGG: tbd:Tbd_2668 9.7e-14 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score:9.99. (368 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (326 aa)
pykPyruvate kinase; KEGG: bce:BC4599 1.3e-131 pyruvate kinase K00873; COG: COG0469 Pyruvate kinase; Psort location: Cytoplasmic, score:8.87. (473 aa)
EDP12152.1ROK family protein; KEGG: bha:BH0797 2.8e-49 glucose kinase K00845; COG: COG1940 Transcriptional regulator/sugar kinase; Psort location: Cytoplasmic, score:9.98. (300 aa)
EDP12160.1Cof-like hydrolase; KEGG: ecc:c0907 4.5e-17 ybiV; putative sugar phosphatase K07757; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (297 aa)
EDP12162.1COG: COG5341 Uncharacterized protein conserved in bacteria. (129 aa)
EDP12163.1KEGG: ctc:CTC01025 3.5e-19 heptaprenyl diphosphate synthase component I K00805; COG: COG4769 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:9.99. (166 aa)
pdxB-2KEGG: eci:UTI89_C3974 3.1e-57 phosphoglycerate dehydrogenase K00018; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (310 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa)
EDP12191.1GIY-YIG catalytic domain protein; KEGG: mca:MCA0838 0.00020 type I restriction-modification system, R subunit K01153; COG: COG2827 Predicted endonuclease containing a URI domain. (96 aa)
EDP12192.1COG: COG5401 Spore germination protein; Psort location: Cytoplasmic, score:8.87. (330 aa)
rexCoA binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (239 aa)
EDP12080.1KEGG: bcz:BCZK3111 2.2e-09 transcriptional regulator, GntR family; COG: COG2188 Transcriptional regulators; Psort location: Cytoplasmic, score:8.87. (225 aa)
cscASucrose-6-phosphate hydrolase; KEGG: bli:BL03892 3.4e-60 sacAA; sucrase-6-phosphate hydrolase K01193; COG: COG1621 Beta-fructosidases (levanase/invertase); Psort location: Cytoplasmic, score:9.65; Belongs to the glycosyl hydrolase 32 family. (435 aa)
EDP12048.1Kinase, PfkB family; KEGG: ser:SERP1494 1.3e-69 fructokinase, putative K00847; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score:9.98. (316 aa)
EDP11823.1Plasmid recombination enzyme; COG: NOG17369 non supervised orthologous group. (365 aa)
EDP11832.1Hypothetical protein; Psort location: Cytoplasmic, score:8.87. (124 aa)
EDP11856.1Hypothetical protein. (113 aa)
EDP11911.1Cof-like hydrolase; KEGG: btl:BALH_4896 2.5e-32 hydrolase, haloacid dehalogenase-like family K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (276 aa)
EDP11924.1Aspartate kinase I; KEGG: bha:BH2400 2.4e-43 dapG; aspartate kinase I K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.87. (242 aa)
EDP11931.1Hypothetical protein; COG: NOG10981 non supervised orthologous group. (248 aa)
EDP11936.1Histidinol phosphate phosphatase HisJ family; KEGG: btk:BT9727_1297 2.3e-32 hisK; histidinol-phosphatase K04486; COG: COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Psort location: Cytoplasmic, score:8.87. (263 aa)
EDP11937.1Kinase, PfkB family; KEGG: ser:SERP1494 1.6e-78 fructokinase, putative K00847; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score:9.98; Belongs to the carbohydrate kinase PfkB family. (322 aa)
EDP11949.1Hypothetical protein; KEGG: tbd:Tbd_2668 4.4e-16 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score:9.99. (380 aa)
EDP11973.1KEGG: cpf:CPF_1229 2.4e-36 histidinol phosphate phosphatase family protein K04486; COG: COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Psort location: Cytoplasmic, score:8.87. (250 aa)
EDP11979.1O-methyltransferase; KEGG: btk:BT9727_4116 4.0e-41 O-methyltransferase; possible caffeoyl-CoA O-methyltransferase K00599; COG: COG4122 Predicted O-methyltransferase; Psort location: Cytoplasmic, score:8.87. (198 aa)
mapMethionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (257 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (215 aa)
EDP12027.1KEGG: sak:SAK_1047 4.2e-46 methyltransferase domain protein K00564; COG: COG2813 16S RNA G1207 methylase RsmC; Psort location: Cytoplasmic, score:8.87. (198 aa)
EDP11421.1CBS domain protein; KEGG: afu:AF0847 1.7e-10 guaB-1; IMP dehydrogenase K00088; COG: COG0517 FOG: CBS domain. (215 aa)
fbaKEGG: cpf:CPF_1557 9.2e-106 fba; fructose-1,6-bisphosphate aldolase, class II K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score:8.87. (288 aa)
purDKEGG: bcz:BCZK0274 5.1e-112 purD; phosphoribosylamine--glycine ligase K01945; COG: COG0151 Phosphoribosylamine-glycine ligase; Psort location: Cytoplasmic, score:8.87; Belongs to the GARS family. (410 aa)
EDP11451.1KEGG: mgm:Mmc1_3649 6.8e-23 ribulose-phosphate 3-epimerase K01783; COG: KOG3111 D-ribulose-5-phosphate 3-epimerase; Psort location: Cytoplasmic, score:8.87. (238 aa)
EDP11455.1Cof-like hydrolase; KEGG: btk:BT9727_5077 9.2e-19 hydrolase, haloacid dehalogenase-like family; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (270 aa)
EDP11457.1Putative fructose-6-phosphate aldolase; KEGG: gme:Gmet_0497 2.4e-36 transaldolase K00616; COG: COG0176 Transaldolase; Psort location: Cytoplasmic, score:8.87. (222 aa)
pfpDiphosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (552 aa)
EDP11488.1Hypothetical protein; KEGG: pub:SAR11_0709 0.0018 gmk; guanylate kinase K00942; Psort location: Cytoplasmic, score:8.87. (201 aa)
EDP11489.1UbiC transcription regulator-associated domain protein; KEGG: reh:H16_A3019 1.2e-11 hutC; histidine utilization repressor; COG: COG2188 Transcriptional regulators; Psort location: Cytoplasmic, score:8.87. (243 aa)
EDP11495.1KEGG: bcl:ABC3505 9.5e-72 fructose-bisphosphate aldolase K01622; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score:8.87. (282 aa)
EDP11496.1SIS domain protein; KEGG: cac:CAC0397 8.2e-06 predicted sugar phosphate aminotransferase involved in capsule formation K08094; COG: COG1737 Transcriptional regulators. (248 aa)
EDP11499.1FAD dependent oxidoreductase; KEGG: cpe:CPE2551 1.7e-129 glpA; probable glycerol-3-phosphate dehydrogenase K00111; COG: COG0579 Predicted dehydrogenase; Psort location: Cytoplasmic, score:8.87. (478 aa)
EDP11503.1Ketose-bisphosphate aldolase; KEGG: cpe:CPE0086 3.4e-51 alf1; fructose-1,6-bisphosphate aldolase K01624; COG: COG0191 Fructose/tagatose bisphosphate aldolase; Psort location: Cytoplasmic, score:8.87. (284 aa)
EDP11510.1Putative ribulose-phosphate 3-epimerase; KEGG: sha:SH1693 1.2e-27 cfxE; ribulose-5-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score:8.87. (218 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (280 aa)
EDP11515.1Transposase, IS605 OrfB family; KEGG: sso:SSO9221 0.0030 rpoM-2; DNA-directed RNA polymerase subunit M K03057; COG: COG0675 Transposase and inactivated derivatives; Psort location: Cytoplasmic, score:8.87. (379 aa)
EDP11525.1KEGG: cpf:CPF_1229 2.2e-40 histidinol phosphate phosphatase family protein K04486; COG: COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Psort location: Cytoplasmic, score:8.87. (265 aa)
metKMethionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (390 aa)
EDP11539.1Aminotransferase, class I/II; KEGG: sde:Sde_1232 1.6e-16 aspartate transaminase K00811; COG: COG1448 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score:9.98. (416 aa)
EDP11540.1Chorismate mutase; KEGG: det:DET0461 5.9e-40 tyrA; chorismate mutase / prephenate dehydratase K04093:K04518; COG: COG0077 Prephenate dehydratase; Psort location: Cytoplasmic, score:9.98. (374 aa)
EDP11541.1KEGG: vpa:VPA1569 1.8e-47 putative transaldolase K08313; COG: COG0176 Transaldolase; Psort location: Cytoplasmic, score:8.87. (226 aa)
pdxB-3KEGG: bcl:ABC0220 3.8e-52 D-3-phosphoglycerate dehydrogenase K00058; COG: COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Psort location: Cytoplasmic, score:9.98; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (322 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (334 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (364 aa)
aroF3-deoxy-7-phosphoheptulonate synthase; KEGG: cac:CAC0892 8.9e-108 phospho-2-dehydro-3-deoxyheptonate aldolase K03856; COG: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Psort location: Cytoplasmic, score:8.87. (338 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (421 aa)
EDP11558.1KEGG: cno:NT01CX_0626 3.6e-56 prephenate dehydrogenase K00210; COG: COG0287 Prephenate dehydrogenase; Psort location: Cytoplasmic, score:8.87. (282 aa)
EDP11566.1Diaminopimelate dehydrogenase; Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate. (327 aa)
miaAtRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (302 aa)
EDP11583.1Transcriptional regulator, RpiR family; KEGG: sep:SE0342 0.00010 hypothetical protein K08094; COG: COG1737 Transcriptional regulators; Psort location: Cytoplasmic, score:8.87. (250 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (281 aa)
rfbBKEGG: ljo:LJ1049 2.2e-134 dTDP-D-glucose 4,6-dehydratase K01710; COG: COG1088 dTDP-D-glucose 4,6-dehydratase; Psort location: Cytoplasmic, score:8.87; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (342 aa)
rfbCdTDP-4-dehydrorhamnose 3,5-epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (191 aa)
rfbAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (297 aa)
galUKEGG: cpe:CPE0506 2.4e-91 galF; UTP-glucose-1-phosphate uridylyltransferase K00963; COG: COG1210 UDP-glucose pyrophosphorylase; Psort location: Cytoplasmic, score:8.87. (290 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (409 aa)
EDP11658.1EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.87. (277 aa)
EDP11659.1KEGG: rru:Rru_A1450 1.2e-07 transcriptional regulator, ArsR family; COG: COG0640 Predicted transcriptional regulators. (101 aa)
purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (146 aa)
EDP11683.1Phosphoribosylformylglycinamidine synthase; KEGG: cac:CAC1655 0. purQ, purL; bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain/glutamine amidotransferase domain) K01952; COG: COG0046 Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; Psort location: Cytoplasmic, score:8.87. (1230 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (472 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; KEGG: bha:BH0631 8.9e-108 purM; phosphoribosylaminoimidazole synthetase K01933; COG: COG0150 Phosphoribosylaminoimidazole (AIR) synthetase; Psort location: Cytoplasmic, score:8.87. (343 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (196 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG: bsu:BG10710 1.3e-177 purH, purJ, purHJ; phosphoribosylaminoimidazole carboxy formyl formyltransferase / inosine-monophosphate cyclohydrolase K00602:K01492; COG: COG0138 AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful); Psort location: Cytoplasmic, score:8.87. (510 aa)
EDP11696.1Aldose 1-epimerase; KEGG: ldb:Ldb1268 5.0e-34 putative mutarotase K01785; COG: COG2017 Galactose mutarotase and related enzymes; Psort location: Cytoplasmic, score:8.87. (293 aa)
EDP11698.1Histidinol phosphate phosphatase HisJ family; KEGG: oih:OB0554 3.9e-43 histidinol phosphatase K04486; COG: COG1387 Histidinol phosphatase and related hydrolases of the PHP family; Psort location: Cytoplasmic, score:8.87. (268 aa)
cscA-2Sucrose-6-phosphate hydrolase; KEGG: bli:BL03892 3.4e-60 sacAA; sucrase-6-phosphate hydrolase K01193; COG: COG1621 Beta-fructosidases (levanase/invertase); Psort location: Cytoplasmic, score:9.65. (435 aa)
EDP11742.1Kinase, PfkB family; KEGG: ser:SERP1494 1.3e-69 fructokinase, putative K00847; COG: COG0524 Sugar kinases, ribokinase family; Psort location: Cytoplasmic, score:9.98. (316 aa)
map-2Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (289 aa)
EDP11761.1KEGG: sak:SAK_0393 4.6e-20 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (270 aa)
prsRibose-phosphate diphosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (322 aa)
rpiBKEGG: gka:GK3371 1.5e-43 ribose 5-phosphate isomerase K01808; COG: COG0698 Ribose 5-phosphate isomerase RpiB; Psort location: Cytoplasmic, score:8.87. (149 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the BPG-independent phosphoglycerate mutase family. (525 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (161 aa)
EDP11789.1Methyltransferase domain protein; KEGG: rty:RT0613 3.3e-09 ubiG; 3-demethylubiquinone-9 3-methyltransferase K00568; COG: COG0500 SAM-dependent methyltransferases; Psort location: Cytoplasmic, score:8.87. (262 aa)
EDP11808.1KEGG: reh:H16_A2208 5.8e-07 rhodanese-like: transcriptional regulator, ArsR family; COG: COG0640 Predicted transcriptional regulators; Psort location: Cytoplasmic, score:8.87. (130 aa)
EDP11811.1KEGG: rru:Rru_A1450 1.9e-05 transcriptional regulator, ArsR family; COG: COG0640 Predicted transcriptional regulators; Psort location: Cytoplasmic, score:8.87. (101 aa)
plsYAcyl-phosphate glycerol 3-phosphate acyltransferase; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (203 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (303 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (355 aa)
dapA-2Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (284 aa)
purCKEGG: sat:SYN_00107 6.3e-75 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923; COG: COG0152 Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase; Psort location: Cytoplasmic, score:8.87; Belongs to the SAICAR synthetase family. (227 aa)
EDP11196.1Methyltransferase small domain protein; KEGG: lsa:LSA1267 8.7e-30 putative methyltransferase K00599; COG: COG4123 Predicted O-methyltransferase; Psort location: Cytoplasmic, score:8.87; Belongs to the methyltransferase superfamily. (221 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (625 aa)
EDP11204.1Polyprenyl synthetase; KEGG: bli:BL01524 6.3e-59 ispAB; polyprenyl synthetase,polyprenyl synthetase K00795; COG: COG0142 Geranylgeranyl pyrophosphate synthase; Psort location: Cytoplasmic, score:9.98. (280 aa)
EDP11208.15'-nucleotidase; KEGG: dps:DP1354 3.8e-84 similar to 5'-nucleotidase K01081; COG: NOG04570 non supervised orthologous group. (307 aa)
ribFRiboflavin biosynthesis protein RibF; KEGG: bha:BH2409 2.3e-52 ribC; riboflavin kinase / FAD synthase K00861:K00953; COG: COG0196 FAD synthase; Psort location: Cytoplasmic, score:8.87; Belongs to the ribF family. (319 aa)
EDP11217.1PP-loop family protein; KEGG: reh:H16_A0260 1.8e-29 predicted ATPase of the PP-loop superfamily implicated in cell cycle control K01529; COG: COG0037 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control; Psort location: Cytoplasmic, score:8.87; Belongs to the TtcA family. (319 aa)
gltAKEGG: tte:TTE0693 8.6e-158 gltD2; NADPH-dependent glutamate synthase beta chain and related oxidoreductases K00266; COG: COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases; Psort location: Cytoplasmic, score:9.98. (462 aa)
aroD3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (260 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (422 aa)
aroF-23-deoxy-7-phosphoheptulonate synthase; KEGG: cac:CAC0892 9.9e-109 phospho-2-dehydro-3-deoxyheptonate aldolase K03856; COG: COG2876 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase; Psort location: Cytoplasmic, score:8.87. (348 aa)
EDP11243.1Putative oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (363 aa)
EDP11253.1Hypothetical protein. (96 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (388 aa)
cdsAKEGG: oih:OB1591 1.5e-32 cdsA; phosphatidate cytidylyltransferase K00981; COG: COG0575 CDP-diglyceride synthetase; Psort location: CytoplasmicMembrane, score:10.00. (257 aa)
uppSDi-trans,poly-cis-decaprenylcistransferase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (236 aa)
trmDtRNA (guanine-N(1)-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (240 aa)
EDP11403.1Putative L-serine ammonia-lyase; KEGG: bfr:BF1265 9.9e-93 L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Psort location: Cytoplasmic, score:8.87. (401 aa)
EDP11413.1Hypothetical protein; KEGG: tbd:Tbd_2668 1.0e-11 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score:9.97. (364 aa)
EDP11022.1Rubredoxin; KEGG: fnu:FN1424 2.4e-265 acyl-CoA dehydrogenase, short-chain specific K00248; COG: COG2025 Electron transfer flavoprotein, alpha subunit; Psort location: Cytoplasmic, score:9.98. (634 aa)
hisZPutative ATP phosphoribosyltransferase, regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (377 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (210 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
EDP11040.1Putative histidinol-phosphate transaminase; KEGG: cno:NT01CX_1063 4.9e-52 hisC; histidinol-phosphate aminotransferase K00817; COG: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (358 aa)
hisBKEGG: cno:NT01CX_1064 1.6e-53 imidazoleglycerol-phosphate dehydratase (IGPD) K01693; COG: COG0131 Imidazoleglycerol-phosphate dehydratase; Psort location: Cytoplasmic, score:8.87. (192 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (205 aa)
hisAKEGG: cno:NT01CX_1065 2.6e-62 hisA; phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814; COG: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; Psort location: Cytoplasmic, score:9.65. (238 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (252 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (108 aa)
hisEKEGG: cac:CAC0943 7.3e-26 his_2; phosphoribosyl-ATP pyrophosphohydrolase K01523; COG: COG0140 Phosphoribosyl-ATP pyrophosphohydrolase; Psort location: Cytoplasmic, score:9.98. (107 aa)
EDP11053.1Glycerate kinase; KEGG: tte:TTE2616 7.0e-76 glycerate kinase K00865; COG: COG1929 Glycerate kinase; Psort location: Cytoplasmic, score:8.87; Belongs to the glycerate kinase type-1 family. (383 aa)
EDP11054.1KEGG: rru:Rru_A1450 3.5e-11 transcriptional regulator, ArsR family; COG: COG0640 Predicted transcriptional regulators. (119 aa)
EDP11056.1Dehydrogenase, FMN-dependent; KEGG: lil:LA1488 4.9e-52 L-lactate dehydrogenase K00016; COG: COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases; Psort location: Cytoplasmic, score:8.87. (340 aa)
malQ4-alpha-glucanotransferase; KEGG: ftl:FTL_0488 3.2e-135 4-alpha-glucanotransferase K00705; COG: COG1640 4-alpha-glucanotransferase; Psort location: Cytoplasmic, score:9.98. (490 aa)
EDP10819.1Alpha amylase, catalytic domain protein; KEGG: fal:FRAAL2309 8.1e-59 cyclomaltodextrinase K01208; COG: COG0366 Glycosidases; Psort location: Cytoplasmic, score:9.98. (533 aa)
EDP10820.1Putative radical SAM protein YgiQ; KEGG: eci:UTI89_C3435 6.2e-123 hypothetical protein; COG: COG1032 Fe-S oxidoreductase; Psort location: Cytoplasmic, score:8.87. (608 aa)
EDP10843.1Hypothetical protein; COG: NOG26052 non supervised orthologous group; Psort location: Cytoplasmic, score:8.87. (565 aa)
ilvAKEGG: chy:CHY_2459 5.4e-101 ilvA2; threonine dehydratase K01754; COG: COG1171 Threonine dehydratase; Psort location: Cytoplasmic, score:8.87. (430 aa)
rpeKEGG: cdi:DIP1320 2.2e-49 rpe; ribulose-phosphate 3-epimerase K01783; COG: COG0036 Pentose-5-phosphate-3-epimerase; Psort location: Cytoplasmic, score:8.87. (220 aa)
EDP10863.1Hypothetical protein; COG: NOG11206 non supervised orthologous group; Psort location: Cytoplasmic, score:8.87. (249 aa)
EDP10867.1Aminotransferase, class I/II; KEGG: bha:BH3313 6.4e-82 patB; aminotransferase K00842; COG: COG1168 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities; Psort location: Cytoplasmic, score:8.87. (410 aa)
EDP10871.1SNARE-like domain protein; KEGG: pat:Patl_0395 1.0e-05 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00520; COG: COG0398 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score:9.99. (186 aa)
EDP10878.1Acetyltransferase, GNAT family; KEGG: lsl:LSL_1772 1.6e-28 wecD; acetyltransferase K00680; COG: COG0454 Histone acetyltransferase HPA2 and related acetyltransferases; Psort location: Cytoplasmic, score:8.87. (143 aa)
EDP10885.1Hypothetical protein; KEGG: tbd:Tbd_2668 3.6e-11 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score:9.99. (390 aa)
EDP10887.1Transcriptional regulator, RpiR family; KEGG: bcn:Bcen_0486 6.3e-28 glucokinase K00845; COG: COG1737 Transcriptional regulators; Psort location: Cytoplasmic, score:8.87. (289 aa)
EDP10990.1General stress protein 13; KEGG: saa:SAUSA300_0486 3.4e-12 polyribonucleotide nucleotidyltransferase K00962; COG: COG1098 Predicted RNA binding protein (contains ribosomal protein S1 domain); Psort location: Cytoplasmic, score:9.98. (114 aa)
pgiKEGG: bli:BL02591 1.9e-130 pgi; glucose-6-phosphate isomerase K01810; COG: COG0166 Glucose-6-phosphate isomerase; Psort location: Cytoplasmic, score:9.98; Belongs to the GPI family. (424 aa)
ppdKKEGG: cpr:CPR_1983 0. ppdK; pyruvate,phosphate dikinase K01006; COG: COG0574 Phosphoenolpyruvate synthase/pyruvate phosphate dikinase; Psort location: Cytoplasmic, score:9.98; Belongs to the PEP-utilizing enzyme family. (875 aa)
EDP10413.1Hypothetical protein; KEGG: eco:b2045 2.2e-06 wcaK; predicted pyruvyl transferase; COG: COG2327 Uncharacterized conserved protein; Psort location: Cytoplasmic, score:8.87. (367 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa)
EDP10439.1Putative glutamyl-tRNA(Gln) amidotransferase, subunit D; KEGG: lac:LBA1687 8.5e-87 ansA; L-asparaginase K01424; COG: COG0252 L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D; Psort location: Cytoplasmic, score:9.98. (353 aa)
EDP10457.1F5/8 type C domain protein; KEGG: aba:Acid345_0650 7.1e-32 alpha-glucosidase K01187; COG: COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases. (2314 aa)
EDP10460.1F5/8 type C domain protein; KEGG: aba:Acid345_0650 1.2e-33 alpha-glucosidase K01187; COG: COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases. (2026 aa)
ldhL-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (316 aa)
EDP10471.1Putative sporulation integral membrane protein YtvI; KEGG: tbd:Tbd_2668 1.1e-11 phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase K01923; COG: COG0628 Predicted permease; Psort location: CytoplasmicMembrane, score:9.99. (347 aa)
EDP10474.1Peptidase family T4; KEGG: mbo:Mb1368 2.2e-47 probable hydrolase; COG: COG3191 L-aminopeptidase/D-esterase; Psort location: Cytoplasmic, score:8.87. (337 aa)
EDP10485.1Hypothetical protein; KEGG: efa:EF2489 8.6e-22 MurB family protein K00075; COG: NOG19084 non supervised orthologous group. (389 aa)
EDP10488.1COG: COG4627 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.87. (323 aa)
EDP10493.1KEGG: lwe:lwe2649 7.9e-29 Cof-like hydrolase K01564; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (296 aa)
nifJKEGG: fnu:FN1170 0. pyruvate-flavodoxin oxidoreductase K03737; COG: COG1013 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit; Psort location: Cytoplasmic, score:8.87. (1168 aa)
EDP10506.1EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.87. (279 aa)
EDP10510.1Hypothetical protein; COG: COG0535 Predicted Fe-S oxidoreductases; Psort location: Cytoplasmic, score:8.87. (345 aa)
proAGlutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (413 aa)
EDP10519.1Putative glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (193 aa)
EDP10527.1KEGG: tde:TDE2512 2.7e-131 aldehyde dehydrogenase (NADP) family protein K00128; COG: COG1012 NAD-dependent aldehyde dehydrogenases; Psort location: Cytoplasmic, score:9.98. (456 aa)
EDP10536.1KEGG: cpr:CPR_1322 1.2e-71 cysK; cysteine synthase A K01738; COG: COG0031 Cysteine synthase; Psort location: Cytoplasmic, score:8.87. (293 aa)
cysEKEGG: hpy:HP1210 3.7e-54 cysE; serine acetyltransferase (CysE) K00640; COG: COG1045 Serine acetyltransferase; Psort location: Cytoplasmic, score:9.98. (176 aa)
EDP10555.1COG: COG4129 Predicted membrane protein; Psort location: CytoplasmicMembrane, score:9.99. (164 aa)
EDP10567.1Putative aconitate hydratase; KEGG: tte:TTE0473 5.5e-211 acnA; Aconitase A K01681; COG: COG1048 Aconitase A; Psort location: Cytoplasmic, score:8.87. (642 aa)
EDP10568.1KEGG: cno:NT01CX_0234 1.2e-112 citrate synthase I K01647; COG: COG0372 Citrate synthase; Psort location: Cytoplasmic, score:9.98. (445 aa)
EDP10569.1Putative isocitrate dehydrogenase, NAD-dependent; KEGG: mta:Moth_0993 2.2e-88 isocitrate dehydrogenase (NAD+) K00030; COG: COG0473 Isocitrate/isopropylmalate dehydrogenase; Psort location: Cytoplasmic, score:9.98. (332 aa)
grpECo-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] (201 aa)
EDP10587.1Haloacid dehalogenase-like hydrolase; KEGG: cvi:CV1402 3.8e-36 probable phosphoglycolate phosphatase K01091; COG: COG0546 Predicted phosphatases; Psort location: Cytoplasmic, score:8.87. (215 aa)
deoDKEGG: msy:MS53_0447 1.9e-59 deoD; purine-nucleoside phosphorylase K03784; COG: COG0813 Purine-nucleoside phosphorylase; Psort location: Cytoplasmic, score:8.87. (239 aa)
EDP10601.1KEGG: lwe:lwe2136 0.00021 acetyltransferase, GNAT family K00680; COG: COG0456 Acetyltransferases; Psort location: Cytoplasmic, score:8.87. (153 aa)
EDP10634.1Inositol monophosphatase family protein; KEGG: hne:HNE_0169 2.0e-05 cysQ; 3'(2'),5'-bisphosphate nucleotidase K01082; COG: COG1218 3-Phosphoadenosine 5-phosphosulfate (PAPS) 3-phosphatase; Psort location: Cytoplasmic, score:8.87. (282 aa)
asnAAspartate--ammonia ligase; KEGG: cno:NT01CX_1288 5.3e-110 asnA; aspartate--ammonia ligase K01914; COG: COG2502 Asparagine synthetase A; Psort location: Cytoplasmic, score:10.00. (338 aa)
EDP10671.1Transcriptional regulator, GntR family; KEGG: bcz:pE33L466_0090 5.2e-48 aminotransferase, MocR-like; COG: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; Psort location: Cytoplasmic, score:9.98. (478 aa)
EDP10681.1Hypothetical protein; KEGG: ece:Z3906m 1.0e-35 yfjD; uncharacterized CBS domain-containing protein K00638; COG: COG1253 Hemolysins and related proteins containing CBS domains; Psort location: CytoplasmicMembrane, score:7.80. (407 aa)
EDP10685.1Putative asparagine synthase (glutamine-hydrolyzing); KEGG: ban:BA1157 2.1e-106 asnO-1; asparagine synthetase, glutamine-hydrolyzing K01953; COG: COG0367 Asparagine synthase (glutamine-hydrolyzing); Psort location: Cytoplasmic, score:8.87. (567 aa)
EDP10703.1KEGG: sak:SAK_0393 1.7e-23 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (267 aa)
tigTrigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (423 aa)
EDP10724.1ATP-grasp domain protein; KEGG: tte:TTE0816 0.00014 carB; Carbamoylphosphate synthase large subunit (split gene in MJ) K01955; COG: NOG08747 non supervised orthologous group; Psort location: Cytoplasmic, score:8.87. (400 aa)
xptXanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (191 aa)
EDP10744.1Cof-like hydrolase; KEGG: eci:UTI89_C4247 1.9e-27 yidA; hypothetical protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (287 aa)
EDP10745.1KEGG: fnu:FN0495 6.2e-139 acetyl-CoA acetyltransferase K00626; COG: COG0183 Acetyl-CoA acetyltransferase; Psort location: Cytoplasmic, score:9.98; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
EDP10746.1acyl-CoA dehydrogenase, C-terminal domain protein; KEGG: cpe:CPE2300 1.6e-140 bcd; butyryl-CoA dehydrogenase, putative K00248; COG: COG1960 Acyl-CoA dehydrogenases; Psort location: Cytoplasmic, score:8.87. (379 aa)
EDP10752.1Beta-eliminating lyase; KEGG: tde:TDE0005 1.3e-92 ltaE; L-threonine aldolase, low-specificity K01620; COG: COG2008 Threonine aldolase; Psort location: Cytoplasmic, score:8.87. (347 aa)
EDP10771.1NQR2 and RnfD family protein; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (502 aa)
EDP10783.1Cof-like hydrolase; KEGG: spz:M5005_Spy_1331 2.4e-26 peptidyl-prolyl cis-trans isomerase K01802; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (256 aa)
EDP10785.1Phospholipase, patatin family; KEGG: vfi:VFA0714 4.8e-12 serine protease; COG: COG4667 Predicted esterase of the alpha-beta hydrolase superfamily; Psort location: Cytoplasmic, score:8.87. (400 aa)
EDP10794.1SIS domain protein; KEGG: bam:Bamb_0825 2.3e-16 glucokinase K00845; COG: COG1737 Transcriptional regulators; Psort location: Cytoplasmic, score:8.87. (281 aa)
EDP10064.1Putative bile acid 7-dehydroxylase 1/3; KEGG: cpf:CPF_1154 1.8e-77 7-alpha-hydroxysteroid dehydrogenase K00076; COG: COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Psort location: Cytoplasmic, score:9.98. (255 aa)
ndkKEGG: mst:Msp_0630 2.9e-15 ndk; nucleoside diphosphate kinase K00940; COG: COG0105 Nucleoside diphosphate kinase; Psort location: Cytoplasmic, score:8.87. (162 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (247 aa)
pgkPhosphoglycerate kinase; KEGG: efa:EF1963 2.0e-133 pgk; phosphoglycerate kinase K00927; COG: COG0126 3-phosphoglycerate kinase; Psort location: Cytoplasmic, score:9.98. (392 aa)
EDP10096.1KEGG: lin:lin0179 1.4e-214 similar to inosine monophosphate dehydrogenase K00088; COG: COG0517 FOG: CBS domain; Psort location: Cytoplasmic, score:8.87. (503 aa)
glgAGlycogen/starch synthase, ADP-glucose type; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (479 aa)
glgDGlucose-1-phosphate adenylyltransferase, GlgD subunit; KEGG: cpe:CPE0069 5.8e-65 glgD; glycogen biosynthesis protein K00975; COG: COG0448 ADP-glucose pyrophosphorylase; Psort location: Cytoplasmic, score:8.87. (371 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (378 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (220 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (428 aa)
dapA-3Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (243 aa)
EDP10147.1Aminotransferase, class I/II; KEGG: cpe:CPE0711 1.6e-117 aspC; aspartate aminotransferase; COG: COG0436 Aspartate/tyrosine/aromatic aminotransferase; Psort location: Cytoplasmic, score:8.87. (388 aa)
EDP10165.1Transcriptional regulator, Spx/MgsR family; KEGG: btl:BALH_4524 8.7e-30 arsC; possible arsenate reductase; COG: COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family. (157 aa)
tilStRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (404 aa)
hptHypoxanthine phosphoribosyltransferase; KEGG: lla:L25115 1.9e-50 hpt; hypoxantine-guanine phosphorybosyltransferase K00760; COG: COG0634 Hypoxanthine-guanine phosphoribosyltransferase; Psort location: Cytoplasmic, score:9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (179 aa)
EDP10182.1Transcriptional regulator, ArsR family; COG: COG0640 Predicted transcriptional regulators; Psort location: Cytoplasmic, score:8.87. (358 aa)
EDP10206.1Hypothetical protein; KEGG: ctc:CTC02272 6.5e-25 purine nucleoside phosphorylase K00755; COG: COG1683 Uncharacterized conserved protein; Psort location: Cytoplasmic, score:8.87. (146 aa)
EDP10208.1Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II; KEGG: gka:GK3297 6.1e-148 phosphomannomutase K01840; COG: COG1109 Phosphomannomutase; Psort location: Cytoplasmic, score:8.87. (564 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position. Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (616 aa)
gpsAKEGG: lmf:LMOf2365_1965 5.7e-81 gpsA; glycerol-3-phosphate dehydrogenase, NAD-dependent K00057; COG: COG0240 Glycerol-3-phosphate dehydrogenase; Psort location: Cytoplasmic, score:8.87. (333 aa)
glgPPhosphorylase, glycogen/starch/alpha-glucan family; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (804 aa)
EDP10242.1EDD domain protein, DegV family; COG: COG1307 Uncharacterized protein conserved in bacteria. (288 aa)
pulAPullulanase, type I; KEGG: bat:BAS4597 4.7e-141 pullulanase, putative K01200; COG: COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases; Psort location: Cytoplasmic, score:8.87; Belongs to the glycosyl hydrolase 13 family. (703 aa)
EDP10255.1Hypothetical protein; Psort location: Cytoplasmic, score:8.87. (175 aa)
gapKEGG: fth:FTH_1121 2.9e-125 gapA; glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) K00134; COG: COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Psort location: Cytoplasmic, score:9.65. (337 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (432 aa)
EDP10320.1Asparaginase; KEGG: lsa:LSA1693 6.1e-93 asnA2; L-asparaginase K01424; COG: COG1446 Asparaginase; Psort location: Cytoplasmic, score:8.87. (319 aa)
EDP10330.1TfoX N-terminal domain protein; COG: COG3070 Regulator of competence-specific genes; Psort location: Cytoplasmic, score:8.87. (106 aa)
EDP10344.1HAD hydrolase, family IA, variant 1; KEGG: lil:LA2702 9.8e-15 phosphoglycolate phosphatase K01091; COG: COG0546 Predicted phosphatases; Psort location: Cytoplasmic, score:8.87. (237 aa)
EDP10347.1SNARE-like domain protein; KEGG: pat:Patl_3732 1.3e-09 phospholipase D K01115; COG: COG0398 Uncharacterized conserved protein; Psort location: CytoplasmicMembrane, score:9.99. (233 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (336 aa)
EDP10350.1Aspartate kinase; KEGG: ldb:Ldb1349 1.5e-119 ask; aspartate kinase K00928; COG: COG0527 Aspartokinases; Psort location: Cytoplasmic, score:8.87; Belongs to the aspartokinase family. (448 aa)
EDP10351.1KEGG: ldb:Ldb1350 8.7e-62 homoserine dehydrogenase K00003; COG: COG0460 Homoserine dehydrogenase; Psort location: Cytoplasmic, score:8.87. (394 aa)
thrCThreonine synthase; KEGG: cac:CAC0999 1.6e-126 thrC; threonine synthase K01733; COG: COG0498 Threonine synthase; Psort location: Cytoplasmic, score:8.87. (499 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (294 aa)
EDP10354.1ACT domain protein; KEGG: cac:CAC1234 6.6e-32 pheB; chorismate mutase PheB of B.subtilis ortholog K06209; COG: COG4492 ACT domain-containing protein; Psort location: Cytoplasmic, score:8.87; Belongs to the UPF0735 family. (154 aa)
mafSeptum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (189 aa)
EDP10361.1KEGG: sak:SAK_0393 4.1e-08 Cof-like hydrolase/peptidyl-prolyl cis-trans isomerase domain protein; COG: COG0561 Predicted hydrolases of the HAD superfamily; Psort location: Cytoplasmic, score:8.87. (287 aa)
Your Current Organism:
Absiella dolichum
NCBI taxonomy Id: 428127
Other names: A. dolichum DSM 3991, Absiella dolichum ATCC 29143, Absiella dolichum DSM 3991, Eubacterium dolichum ATCC 29143, Eubacterium dolichum DSM 3991, Eubacterium dolichum strain DSM 3991
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