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| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa) |
| | Adeg_0884 | TIGRFAM: aspartate kinase; aspartate kinase, monofunctional class; PFAM: aspartate/glutamate/uridylate kinase; amino acid-binding ACT domain protein; KEGG: pca:Pcar_1006 aspartate kinase; Belongs to the aspartokinase family. (408 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (510 aa) |
| | Adeg_0892 | TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein; KEGG: dat:HRM2_04850 NrdD. (695 aa) |
| | Adeg_0930 | Cobalt ABC transporter, ATPase subunit; KEGG: dar:Daro_1694 cobalt transport protein ATP-binding subunit; TIGRFAM: cobalt ABC transporter, ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase. (272 aa) |
| | Adeg_0940 | PFAM: protein of unknown function DUF265; SMART: AAA ATPase; KEGG: GF10190 gene product from transcript GF10190-RA. (181 aa) |
| | Adeg_0975 | KEGG: dat:HRM2_05520 putative CRISPR-associated helicase Cas3 (ATP-dependent DNA helicase); TIGRFAM: CRISPR-associated helicase Cas3; PFAM: helicase domain protein; SMART: DEAD-like helicase. (821 aa) |
| | Adeg_0980 | Hypothetical protein. (710 aa) |
| | Adeg_0989 | KEGG: gur:Gura_3491 GTPase or GTP-binding protein-like protein. (371 aa) |
| | pstB | Phosphate ABC transporter, ATPase subunit; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (251 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (916 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (204 aa) |
| | Adeg_1029 | Hypothetical protein. (410 aa) |
| | Adeg_1041 | PFAM: type II secretion system protein E; KEGG: bph:Bphy_5324 type II secretion system protein E. (444 aa) |
| | Adeg_1058 | Hypothetical protein. (122 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (393 aa) |
| | Adeg_1092 | PFAM: UvrD/REP helicase; KEGG: geo:Geob_0379 UvrD/REP helicase. (707 aa) |
| | gatC | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (93 aa) |
| | gatA | glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (489 aa) |
| | gatB | glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (479 aa) |
| | Adeg_1104 | PFAM: ABC transporter related; ABC nitrate/sulphonate/bicarbonate family transporter, ATPase subunit; SMART: AAA ATPase; KEGG: gme:Gmet_0523 ABC transporter-related protein. (426 aa) |
| | Adeg_1105 | PFAM: binding-protein-dependent transport systems inner membrane component; KEGG: lpp:lpp0135 hypothetical protein. (572 aa) |
| | panC | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (289 aa) |
| | ddl | D-alanine/D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (308 aa) |
| | Adeg_1138 | Chromosome segregation ATPase-like protein; KEGG: hypothetical protein. (433 aa) |
| | cmk | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: geo:Geob_2362 cytidylate kinase. (218 aa) |
| | Adeg_1168 | Transcriptional activator of acetoin/glycerol metabolism-like protein; KEGG: dat:HRM2_47650 signal-transduction and transcriptional-control protein. (180 aa) |
| | Adeg_1170 | PFAM: Thiamine biosynthesis protein-like; KEGG: sat:SYN_01419 putative tRNA (5-methylaminomethyl-2-thiouridylate) -methyltransferase / fibronectin/fibrinogen-binding protein. (329 aa) |
| | Adeg_1177 | PFAM: Bifunctional DNA primase/polymerase; Primase 1; KEGG: dol:Dole_2704 bifunctional DNA primase/polymerase. (283 aa) |
| | Adeg_1178 | KEGG: sfu:Sfum_2502 hypothetical protein. (430 aa) |
| | Adeg_1193 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pca:Pcar_3057 ATP-binding component of citrate-dependent iron (III) transport protein. (250 aa) |
| | Adeg_1205 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: aeh:Mlg_2035 ABC transporter related. (251 aa) |
| | Adeg_1214 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: tdn:Suden_2064 ABC transporter-related protein. (245 aa) |
| | pfkA-2 | Phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (368 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (214 aa) |
| | Adeg_1239 | KEGG: dma:DMR_33020 hypothetical protein. (88 aa) |
| | Adeg_1283 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | Adeg_1300 | KEGG: dol:Dole_2757 tryptophanyl-tRNA synthetase; TIGRFAM: tryptophanyl-tRNA synthetase; PFAM: aminoacyl-tRNA synthetase class Ib. (324 aa) |
| | Adeg_1302 | PFAM: CBS domain containing protein; Polynucleotide adenylyltransferase region; phosphoesterase DHHA1; phosphoesterase RecJ domain protein; SMART: CBS domain containing protein; KEGG: sfu:Sfum_0679 polynucleotide adenylyltransferase region; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (769 aa) |
| | Adeg_1311 | PFAM: Serine/threonine protein kinase-related; tyrosine protein kinase; PASTA domain containing protein; SMART: serine/threonine protein kinase; tyrosine protein kinase; PASTA domain containing protein; KEGG: azo:azo3774 putative serine/threonine protein kinase. (584 aa) |
| | Adeg_1328 | ATPase-like, ParA/MinD; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (302 aa) |
| | Adeg_1345 | PFAM: helicase domain protein; SNF2-related protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: rpf:Rpic12D_2671 helicase domain protein. (953 aa) |
| | Adeg_1368 | Hypothetical protein; KEGG: sat:SYN_01836 MreB-like ATPase involved in cell division. (333 aa) |
| | Adeg_1370 | PFAM: ATP-binding region ATPase domain protein; KEGG: afw:Anae109_2771 DNA topoisomerase VI subunit B. (882 aa) |
| | Adeg_1371 | KEGG: mxa:MXAN_1883 hypothetical protein. (550 aa) |
| | Adeg_1373 | Replicative DNA helicase-like protein; KEGG: lhk:LHK_01738 DnaB. (460 aa) |
| | Adeg_1387 | KEGG: dal:Dalk_2229 putative ATP/GTP-binding protein. (229 aa) |
| | Adeg_1391 | PFAM: Thiamin pyrophosphokinase catalytic region. (372 aa) |
| | Adeg_1394 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (551 aa) |
| | nadK | NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (288 aa) |
| | Adeg_1401 | TIGRFAM: stage IV sporulation protein A; PFAM: Sporulation stage IV protein A. (490 aa) |
| | rgy | Reverse gyrase; Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication; In the C-terminal section; belongs to the prokaryotic type I/III topoisomerase family. (1143 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (874 aa) |
| | Adeg_1445 | PFAM: SEC-C motif domain protein; KEGG: glo:Glov_2998 sec-C motif domain protein. (419 aa) |
| | Adeg_1465 | TIGRFAM: alpha-ribazole phosphatase; PFAM: Phosphoglycerate mutase; KEGG: azo:azo2798 phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (205 aa) |
| | kdpB | K+-transporting ATPase, B subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (673 aa) |
| | kdpC | Potassium-transporting ATPase, C subunit; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (205 aa) |
| | Adeg_1488 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dat:HRM2_48730 LivG5. (259 aa) |
| | Adeg_1489 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfu:Sfum_0838 ABC transporter related. (251 aa) |
| | Adeg_1534 | TIGRFAM: septum site-determining protein MinD; PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sfu:Sfum_1281 septum site-determining protein MinD. (264 aa) |
| | Adeg_1540 | TIGRFAM: cell shape determining protein, MreB/Mrl family; PFAM: cell shape determining protein MreB/Mrl; cell division protein FtsA; KEGG: gme:Gmet_0918 rod shape-determining protein MreB. (344 aa) |
| | Adeg_1548 | KEGG: cla:Cla_0048 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: ATP-cone domain protein. (670 aa) |
| | nrdR | ATP-cone domain protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (163 aa) |
| | murC | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (461 aa) |
| | murD | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (457 aa) |
| | murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate/D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (464 aa) |
| | murE | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (492 aa) |
| | Adeg_1593 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: azo:azo3442 ABC transporter ATP-binding protein. (263 aa) |
| | Adeg_1598 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfr:Sfri_1831 ABC transporter related. (260 aa) |
| | pgk | PFAM: phosphoglycerate kinase; KEGG: pca:Pcar_1332 phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (392 aa) |
| | Adeg_1621 | Conserved hypothetical protein; Displays ATPase and GTPase activities. (288 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (347 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (193 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (243 aa) |
| | Adeg_1642 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dal:Dalk_3521 ABC transporter related. (274 aa) |
| | lysS | KEGG: gsu:GSU2271 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetase class II (D K and N); tRNA synthetase class II (G H P and S); nucleic acid binding OB-fold tRNA/helicase-type; Belongs to the class-II aminoacyl-tRNA synthetase family. (489 aa) |
| | Adeg_1658 | TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: FAD synthetase; Riboflavin kinase; KEGG: dma:DMR_06190 riboflavin kinase/FMN adenylyltransferase; Belongs to the ribF family. (319 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (637 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (597 aa) |
| | hisS | KEGG: ank:AnaeK_2357 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (429 aa) |
| | Adeg_1686 | TIGRFAM: stage III sporulation protein AA; KEGG: Os07g0187400; hypothetical protein. (323 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (405 aa) |
| | Adeg_1700 | TIGRFAM: acetyl coenzyme A synthetase (ADP forming), alpha domain protein; PFAM: CoA-binding domain protein; KEGG: dma:DMR_20040 CoA-binding domain protein. (699 aa) |
| | Adeg_1702 | PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: hha:Hhal_0638 IstB ATP binding domain-containing protein. (245 aa) |
| | Adeg_1704 | Adenosylcobinamide-phosphate guanylyltransferase; PFAM: cobalbumin biosynthesis protein; protein of unknown function DUF503; KEGG: aeh:Mlg_2824 adenosylcobinamide kinase. (280 aa) |
| | Adeg_1712 | KEGG: sulfate adenylyltransferase; K00958 sulfate adenylyltransferase; TIGRFAM: sulfate adenylyltransferase; PFAM: ATP-sulfurylase. (451 aa) |
| | Adeg_1724 | KEGG: ade:Adeh_0623 twitching motility protein; TIGRFAM: twitching motility protein; PFAM: type II secretion system protein E; SMART: AAA ATPase. (360 aa) |
| | Adeg_1725 | General secretory pathway protein E; KEGG: scl:sce4467 type IV pilus biogenesis protein PilB; TIGRFAM: general secretory pathway protein E; PFAM: type II secretion system protein E; General secretory system II protein E domain protein; SMART: AAA ATPase. (553 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (611 aa) |
| | Adeg_1730 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (781 aa) |
| | Adeg_1731 | Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (277 aa) |
| | glyS | KEGG: sat:SYN_01537 glycyl-tRNA synthetase subunit beta; TIGRFAM: glycyl-tRNA synthetase, beta subunit. (690 aa) |
| | glyQ | KEGG: pca:Pcar_0598 glycyl-tRNA synthetase subunit alpha; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit. (291 aa) |
| | Adeg_1748 | Hypothetical protein; KEGG: mms:mma_2886 RecN DNA repair protein. (222 aa) |
| | nnrE | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] (530 aa) |
| | Adeg_1763 | TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; Heavy metal transport/detoxification protein; Haloacid dehalogenase domain protein hydrolase; KEGG: tbd:Tbd_2266 heavy metal translocating P-type ATPase. (720 aa) |
| | Adeg_1768 | KEGG: mpt:Mpe_B0327 hypothetical protein. (407 aa) |
| | Adeg_1769 | Hypothetical protein; KEGG: hch:HCH_03464 methyl-accepting chemotaxis protein. (330 aa) |
| | Adeg_1777 | PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein; KEGG: predicted protein; K06877. (970 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: gsu:GSU2209 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (824 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (945 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (681 aa) |
| | argG | Argininosuccinate synthase; KEGG: hypothetical protein LOC100266261; K01940 argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; PFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (284 aa) |
| | Adeg_1834 | PFAM: ABC transporter, ATPase, predicted; KEGG: dat:HRM2_34010 ATPase family protein. (570 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (242 aa) |
| | Adeg_1862 | PFAM: phosphoribulokinase/uridine kinase; KEGG: phosphoribulokinase; K00855 phosphoribulokinase. (299 aa) |
| | coaX | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (254 aa) |
| | birA | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (332 aa) |
| | panC-2 | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (288 aa) |
| | Adeg_1882 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (292 aa) |
| | Adeg_1910 | KEGG: dal:Dalk_3532 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; von Willebrand factor type A; SMART: von Willebrand factor type A; AAA ATPase. (660 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (315 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (560 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (865 aa) |
| | Adeg_1944 | PFAM: cell division FtsK/SpoIIIE; DNA translocase ftsK gamma; SMART: AAA ATPase; KEGG: dal:Dalk_3204 cell division FtsK/SpoIIIE; Belongs to the FtsK/SpoIIIE/SftA family. (726 aa) |
| | Adeg_1948 | PFAM: ATPase AAA-2 domain protein; Clp ATPase-like; AAA ATPase central domain protein; UvrB/UvrC protein; ATPase associated with various cellular activities AAA_5; Clp domain protein; SMART: AAA ATPase; KEGG: SORBIDRAFT_06g014590; hypothetical protein; Belongs to the ClpA/ClpB family. (812 aa) |
| | mcsB | ATP:guanido phosphotransferase; Catalyzes the specific phosphorylation of arginine residues in proteins. (356 aa) |
| | Adeg_1964 | PFAM: Circadian clock protein KaiC central region; KEGG: nis:NIS_1761 ATPase. (281 aa) |
| | Adeg_1984 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: mxa:MXAN_4199 putative macrolide efflux ABC transporter, ATP-binding protein. (228 aa) |
| | Adeg_2000 | KEGG: sfu:Sfum_2502 hypothetical protein. (431 aa) |
| | Adeg_2001 | PFAM: Bifunctional DNA primase/polymerase; Primase 1; KEGG: dol:Dole_2704 bifunctional DNA primase/polymerase. (283 aa) |
| | Adeg_2027 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: sat:SYN_02828 flagellar synthesis regulator. (283 aa) |
| | Adeg_2041 | KEGG: gem:GM21_3919 ATPase, FliI/YscN family; TIGRFAM: flagellar protein export ATPase FliI; ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase. (436 aa) |
| | Adeg_2048 | Transcriptional regulator, LuxR family; PFAM: regulatory protein LuxR; Sigma-70 region 4 type 2; SMART: regulatory protein LuxR; KEGG: azo:azo2940 sigma-54 dependent transcriptional regulator. (280 aa) |
| | Adeg_2055 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: dvl:Dvul_2857 ABC transporter related. (244 aa) |
| | fhs | PFAM: formate-tetrahydrofolate ligase FTHFS; KEGG: fthS; formate-dihydrofolate ligase; K01938 formate--tetrahydrofolate ligase; Belongs to the formate--tetrahydrofolate ligase family. (567 aa) |
| | ndk | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (149 aa) |
| | ftsH | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (639 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (471 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (290 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1123 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (298 aa) |
| | Adeg_2113 | KEGG: sfu:Sfum_1039 cob(I)alamin adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. (174 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (512 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (202 aa) |
| | Adeg_2126 | KEGG: dal:Dalk_2229 putative ATP/GTP-binding protein. (216 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (427 aa) |
| | Adeg_2134 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (441 aa) |
| | Adeg_2143 | Hypothetical protein. (163 aa) |
| | Adeg_2146 | PFAM: Cobyrinic acid ac-diamide synthase; KEGG: geo:Geob_0454 cobyrinic acid ac-diamide synthase. (254 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (444 aa) |
| | recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (358 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (636 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (802 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | cbiA | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (460 aa) |
| | argS | KEGG: gem:GM21_1940 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (564 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (547 aa) |
| | Adeg_0054 | PFAM: response regulator receiver; SMART: response regulator receiver; KEGG: mlo:mll3126 two-component response regulator. (109 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (458 aa) |
| | Adeg_0067 | Sua5/YciO/YrdC/YwlC family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (338 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (507 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (287 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (475 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (139 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (166 aa) |
| | recG | ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (685 aa) |
| | Adeg_0134 | PFAM: PhoH family protein; KEGG: mxa:MXAN_4738 PhoH family protein. (319 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (339 aa) |
| | Adeg_0159 | TIGRFAM: 5-formyltetrahydrofolate cyclo-ligase; PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: gsu:GSU1136 5-formyltetrahydrofolate cyclo-ligase family protein; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (199 aa) |
| | groS | Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (94 aa) |
| | groL | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (539 aa) |
| | Adeg_0173 | Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: ssn:SSON_2279 acetoacetate metabolism regulatory protein AtoC. (463 aa) |
| | Adeg_0177 | PFAM: peptidase S16 lon domain protein; KEGG: geo:Geob_1956 peptidase S16 lon domain protein. (818 aa) |
| | cbiA-2 | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (458 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (373 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (190 aa) |
| | mnmA | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (344 aa) |
| | Adeg_0281 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: ppd:Ppro_1258 ABC transporter related. (393 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (882 aa) |
| | Adeg_0295 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: sfu:Sfum_1671 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. (426 aa) |
| | selD | Selenide, water dikinase; Synthesizes selenophosphate from selenide and ATP. (347 aa) |
| | purC | KEGG: cco:CCC13826_0132 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (241 aa) |
| | purM | KEGG: gbm:Gbem_2402 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein domain protein; AIR synthase related protein. (346 aa) |
| | purD | KEGG: dps:DP2188 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; protein of unknown function DUF201; ATP-grasp domain protein; Belongs to the GARS family. (426 aa) |
| | hisI | TIGRFAM: phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; phosphoribosyl-ATP pyrophosphohydrolase; KEGG: nis:NIS_1544 histidine biosynthesis bifunctional protein HisI; In the N-terminal section; belongs to the PRA-CH family. (242 aa) |
| | Adeg_0353 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: bpa:BPP0962 putative ABC transport proteins, ATP-binding component. (253 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: Carbamoyl-phosphate synthase small chain; glutamine amidotransferase class-I; KEGG: pca:Pcar_1613 carbamoyl phosphate synthase small subunit; Belongs to the CarA family. (359 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; protein of unknown function DUF201; RimK domain protein ATP-grasp; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; MGS domain protein; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; KEGG: dat:HRM2_47760 CarB2; Belongs to the CarB family. (1075 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (443 aa) |
| | disA | DNA integrity scanning, DisA, linker region; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis. (352 aa) |
| | cysS | KEGG: tgr:Tgr7_0936 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia; Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Belongs to the class-I aminoacyl-tRNA synthetase family. (474 aa) |
| | Adeg_0412 | KEGG: dma:DMR_07210 hypothetical protein. (911 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | Adeg_0440 | TIGRFAM: pyruvate kinase; PFAM: Pyruvate kinase barrel; PEP-utilising protein mobile region; Pyruvate kinase alpha/beta; KEGG: dps:DP3116 pyruvate kinase; Belongs to the pyruvate kinase family. (586 aa) |
| | Adeg_0442 | Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (955 aa) |
| | Adeg_0443 | PFAM: domain of unknown function DUF1727; Mur ligase middle domain protein; KEGG: gme:Gmet_0408 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase. (463 aa) |
| | secA | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (888 aa) |
| | ftsE | Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (229 aa) |
| | Adeg_0472 | Protein of unknown function DUF214; Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (296 aa) |
| | clpX | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (420 aa) |
| | Adeg_0492 | Sigma 54 interacting domain protein; KEGG: gsu:GSU1790 ATP-dependent protease La; TIGRFAM: ATP-dependent protease LonB; PFAM: AAA ATPase central domain protein; peptidase S16 lon domain protein; ATPase associated with various cellular activities AAA_5; magnesium chelatase ChlI subunit; SMART: AAA ATPase. (557 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (797 aa) |
| | Adeg_0507 | Hypothetical protein. (60 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (494 aa) |
| | Adeg_0532 | Two component, sigma54 specific, transcriptional regulator, Fis family; PFAM: sigma-54 factor interaction domain-containing protein; helix-turn-helix Fis-type; response regulator receiver; ATPase associated with various cellular activities AAA_5; SMART: response regulator receiver; AAA ATPase; KEGG: afw:Anae109_2442 two component, sigma54 specific, fis family transcriptional regulator. (470 aa) |
| | pheS | KEGG: glo:Glov_1873 phenylalanyl-tRNA synthetase, alpha subunit; TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (340 aa) |
| | pheT | TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: mxa:MXAN_3595 phenylalanyl-tRNA synthetase subunit beta; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (780 aa) |
| | mutS2 | MutS2 family protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily. (775 aa) |
| | Adeg_0547 | PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: sfu:Sfum_0164 ABC transporter related. (262 aa) |
| | Adeg_0556 | KEGG: dal:Dalk_3533 magnesium chelatase; PFAM: magnesium chelatase ChlI subunit; SMART: AAA ATPase. (346 aa) |
| | Adeg_0557 | KEGG: sfu:Sfum_1827 ABC transporter related; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase. (279 aa) |
| | Adeg_0560 | KEGG: mes:Meso_2894 daunorubicin resistance ABC transporter ATPase subunit; TIGRFAM: daunorubicin resistance ABC transporter ATPase subunit; PFAM: ABC transporter related; SMART: AAA ATPase. (324 aa) |
| | Adeg_0567 | TIGRFAM: GTP-binding protein YchF; PFAM: Protein of unknown function DUF933; GTP-binding protein HSR1-related; KEGG: ank:AnaeK_4473 GTP-dependent nucleic acid-binding protein EngD. (359 aa) |
| | hslU | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (463 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (255 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (574 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). (219 aa) |
| | Adeg_0605 | PFAM: chaperonin Cpn60/TCP-1; KEGG: hypothetical protein; K09495 T-complex protein 1 subunit gamma. (524 aa) |
| | grpE | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] (210 aa) |
| | dnaK | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (605 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (381 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (256 aa) |
| | Adeg_0625 | Vesicle-fusing ATPase; KEGG: ade:Adeh_1774 FtsH-2 peptidase; PFAM: AAA ATPase central domain protein; peptidase M41; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; Belongs to the AAA ATPase family. (500 aa) |
| | recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (346 aa) |
| | Adeg_0642 | PFAM: ABC transporter related; Transport-associated OB domain protein; SMART: AAA ATPase; KEGG: sat:SYN_00079 ABC-type sugar transport systems, ATPase component; Belongs to the ABC transporter superfamily. (342 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (178 aa) |
| | Adeg_0681 | PFAM: AAA ATPase central domain protein; SMART: AAA ATPase; KEGG: mxa:MXAN_5695 AAA family ATPase. (567 aa) |
| | Adeg_0731 | SMART: AAA ATPase; KEGG: mpt:Mpe_B0371 F-pilin subunit assembly into extended F pili. (569 aa) |
| | Adeg_0749 | Hypothetical protein; KEGG: TAF4; TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa; K03129 transcription initiation factor TFIID subunit D3. (537 aa) |
| | Adeg_0750 | Hypothetical protein. (146 aa) |
| | Adeg_0776 | KEGG: afw:Anae109_3967 Flp pilus assembly protein ATPase CpaE-like protein. (365 aa) |
| | Adeg_0777 | Hypothetical protein; KEGG: lhk:LHK_00966 probable partition-related protein. (352 aa) |
| | Adeg_0779 | ATPase involved in chromosome partitioning-like protein; KEGG: rso:RSc0653 putative pilus assembly protein. (431 aa) |
| | Adeg_0780 | PFAM: type II secretion system protein E; KEGG: pla:Plav_0072 type II secretion system protein E. (431 aa) |
| | Adeg_0799 | PFAM: filamentation induced by cAMP protein Fic; KEGG: bur:Bcep18194_B2094 filamentation induced by cAMP protein Fic. (267 aa) |
| | Adeg_0805 | Hypothetical protein. (1282 aa) |
| | Adeg_0810 | PFAM: filamentation induced by cAMP protein Fic; KEGG: bur:Bcep18194_B2094 filamentation induced by cAMP protein Fic. (267 aa) |
| | Adeg_0813 | KEGG: dal:Dalk_4977 hypothetical protein. (324 aa) |
| | Adeg_0827 | KEGG: aeh:Mlg_1542 DEAD/DEAH box helicase domain-containing protein. (1036 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (202 aa) |
| | Adeg_0853 | PFAM: AAA ATPase central domain protein; ATPase associated with various cellular activities AAA_5; SMART: AAA ATPase; KEGG: ade:Adeh_2708 ATPase associated with various cellular activities, AAA-5. (306 aa) |
| | Adeg_0855 | PFAM: RQC domain. (607 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (730 aa) |
| | spoIIAB | Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (142 aa) |
| | Adeg_0874 | Replicative DNA helicase-like protein; KEGG: lhk:LHK_01738 DnaB. (460 aa) |
