(19 nodes) Butanoate metabolism network (Trichoderma reesei)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	G0R7I2_HYPJQ	Uncharacterized protein. (318 aa)
	G0R861_HYPJQ	Small regulatory subunit of acetolactate synthase. (311 aa)
	G0R8N2_HYPJQ	Acetolactate synthase. (683 aa)
	G0RAV6_HYPJQ	Mitochondrial acetoacetyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
	G0RBA5_HYPJQ	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (453 aa)
	G0RD72_HYPJQ	Predicted protein; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
	G0RDA5_HYPJQ	Hydroxymethylglutaryl-CoA lyase. (373 aa)
	G0REH4_HYPJQ	Predicted protein. (696 aa)
	G0RGT4_HYPJQ	Predicted protein. (708 aa)
	G0RH60_HYPJQ	Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (460 aa)
	G0RHX9_HYPJQ	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (519 aa)
	G0RI23_HYPJQ	Glutamate decarboxylase. (513 aa)
	G0RLK7_HYPJQ	Glutamate decarboxylase; Belongs to the group II decarboxylase family. (547 aa)
	G0RNE6_HYPJQ	Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
	G0RNP2_HYPJQ	Predicted protein; Belongs to the aldehyde dehydrogenase family. (785 aa)
	G0RQY9_HYPJQ	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate. (551 aa)
	G0RRY6_HYPJQ	Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (469 aa)
	G0RTQ1_HYPJQ	Predicted protein; Belongs to the enoyl-CoA hydratase/isomerase family. (257 aa)
	G0RWK3_HYPJQ	Succinate semialdehyde dehydrogenase. (498 aa)

Your Current Organism:

Trichoderma reesei

NCBI taxonomy Id: 431241
Other names: T. reesei QM6a, Trichoderma reesei QM6a

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G0R7I2_HYPJQ	G0RAV6_HYPJQ	G0R7I2	G0RAV6	Uncharacterized protein.	Mitochondrial acetoacetyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.978
G0R7I2_HYPJQ	G0RBA5_HYPJQ	G0R7I2	G0RBA5	Uncharacterized protein.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.903
G0R7I2_HYPJQ	G0RD72_HYPJQ	G0R7I2	G0RD72	Uncharacterized protein.	Predicted protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.996
G0R7I2_HYPJQ	G0RDA5_HYPJQ	G0R7I2	G0RDA5	Uncharacterized protein.	Hydroxymethylglutaryl-CoA lyase.	0.414
G0R7I2_HYPJQ	G0REH4_HYPJQ	G0R7I2	G0REH4	Uncharacterized protein.	Predicted protein.	0.944
G0R7I2_HYPJQ	G0RGT4_HYPJQ	G0R7I2	G0RGT4	Uncharacterized protein.	Predicted protein.	0.944
G0R7I2_HYPJQ	G0RHX9_HYPJQ	G0R7I2	G0RHX9	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.925
G0R7I2_HYPJQ	G0RNE6_HYPJQ	G0R7I2	G0RNE6	Uncharacterized protein.	Predicted protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.979
G0R7I2_HYPJQ	G0RQY9_HYPJQ	G0R7I2	G0RQY9	Uncharacterized protein.	Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.	0.925
G0R7I2_HYPJQ	G0RTQ1_HYPJQ	G0R7I2	G0RTQ1	Uncharacterized protein.	Predicted protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.995
G0R861_HYPJQ	G0R8N2_HYPJQ	G0R861	G0R8N2	Small regulatory subunit of acetolactate synthase.	Acetolactate synthase.	0.999
G0R861_HYPJQ	G0RDA5_HYPJQ	G0R861	G0RDA5	Small regulatory subunit of acetolactate synthase.	Hydroxymethylglutaryl-CoA lyase.	0.563
G0R8N2_HYPJQ	G0R861_HYPJQ	G0R8N2	G0R861	Acetolactate synthase.	Small regulatory subunit of acetolactate synthase.	0.999
G0R8N2_HYPJQ	G0RDA5_HYPJQ	G0R8N2	G0RDA5	Acetolactate synthase.	Hydroxymethylglutaryl-CoA lyase.	0.479
G0RAV6_HYPJQ	G0R7I2_HYPJQ	G0RAV6	G0R7I2	Mitochondrial acetoacetyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.978
G0RAV6_HYPJQ	G0RBA5_HYPJQ	G0RAV6	G0RBA5	Mitochondrial acetoacetyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.	3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.	0.994
G0RAV6_HYPJQ	G0RD72_HYPJQ	G0RAV6	G0RD72	Mitochondrial acetoacetyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.	Predicted protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.881
G0RAV6_HYPJQ	G0RDA5_HYPJQ	G0RAV6	G0RDA5	Mitochondrial acetoacetyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.	Hydroxymethylglutaryl-CoA lyase.	0.939
G0RAV6_HYPJQ	G0REH4_HYPJQ	G0RAV6	G0REH4	Mitochondrial acetoacetyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.	Predicted protein.	0.953
G0RAV6_HYPJQ	G0RGT4_HYPJQ	G0RAV6	G0RGT4	Mitochondrial acetoacetyl-CoA thiolase-like protein; Belongs to the thiolase-like superfamily. Thiolase family.	Predicted protein.	0.953