(34 nodes) 2-Oxocarboxylic acid metabolism network (Trichoderma reesei)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	G0R842_HYPJQ	Dehydratase. (616 aa)
	G0R861_HYPJQ	Small regulatory subunit of acetolactate synthase. (311 aa)
	G0R8N2_HYPJQ	Acetolactate synthase. (683 aa)
	idh2	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (379 aa)
	G0RA60_HYPJQ	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (778 aa)
	G0RAE7_HYPJQ	N-acetyltransferase domain-containing protein. (604 aa)
	G0RAX4_HYPJQ	Aspartate aminotransferase. (414 aa)
	G0RBX3_HYPJQ	Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (369 aa)
	G0RBY4_HYPJQ	Branched-chain amino acid aminotransferase. (400 aa)
	G0RBY9_HYPJQ	Predicted protein. (318 aa)
	G0RC37_HYPJQ	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (409 aa)
	G0RDF0_HYPJQ	Aminotransferase. (548 aa)
	G0RFA6_HYPJQ	Dehydratase. (607 aa)
	G0RFT7_HYPJQ	Amino transferase. (438 aa)
	G0RGS3_HYPJQ	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate; Belongs to the ArgJ family. (447 aa)
	G0RIR9_HYPJQ	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (787 aa)
	cit1	Citrate synthase; Belongs to the citrate synthase family. (472 aa)
	G0RLK6_HYPJQ	Acetylornithine aminotransferase-like protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (420 aa)
	G0RLM5_HYPJQ	Isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (367 aa)
	G0RM40_HYPJQ	Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (811 aa)
	G0RMN2_HYPJQ	Aspartate-semialdehyde dehydrogenase. (362 aa)
	G0RNI5_HYPJQ	Alanine transaminase-like protein. (480 aa)
	G0RNL3_HYPJQ	Isopropylmalate/homocitrate/citramalate synthase. (616 aa)
	G0RQR9_HYPJQ	Dehydratase family. (604 aa)
	G0RRP4_HYPJQ	Citrate synthase; Belongs to the citrate synthase family. (474 aa)
	G0RSB3_HYPJQ	Aspartate aminotransferase. (425 aa)
	G0RSU4_HYPJQ	Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (424 aa)
	G0RTE6_HYPJQ	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (404 aa)
	G0RTT9_HYPJQ	Predicted protein. (356 aa)
	G0RU29_HYPJQ	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (784 aa)
	G0RUQ0_HYPJQ	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (410 aa)
	G0RUX6_HYPJQ	Isocitrate dehydrogenase. (417 aa)
	G0RV43_HYPJQ	Aspartokinase. (513 aa)
	G0RWK5_HYPJQ	Beta-isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (380 aa)

Your Current Organism:

Trichoderma reesei

NCBI taxonomy Id: 431241
Other names: T. reesei QM6a, Trichoderma reesei QM6a

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G0R842_HYPJQ	G0R861_HYPJQ	G0R842	G0R861	Dehydratase.	Small regulatory subunit of acetolactate synthase.	0.673
G0R842_HYPJQ	G0R8N2_HYPJQ	G0R842	G0R8N2	Dehydratase.	Acetolactate synthase.	0.766
G0R842_HYPJQ	G0RA60_HYPJQ	G0R842	G0RA60	Dehydratase.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.830
G0R842_HYPJQ	G0RBX3_HYPJQ	G0R842	G0RBX3	Dehydratase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.404
G0R842_HYPJQ	G0RBY4_HYPJQ	G0R842	G0RBY4	Dehydratase.	Branched-chain amino acid aminotransferase.	0.968
G0R842_HYPJQ	G0RC37_HYPJQ	G0R842	G0RC37	Dehydratase.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.968
G0R842_HYPJQ	G0RFA6_HYPJQ	G0R842	G0RFA6	Dehydratase.	Dehydratase.	0.912
G0R842_HYPJQ	G0RLM5_HYPJQ	G0R842	G0RLM5	Dehydratase.	Isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.410
G0R842_HYPJQ	G0RMN2_HYPJQ	G0R842	G0RMN2	Dehydratase.	Aspartate-semialdehyde dehydrogenase.	0.523
G0R842_HYPJQ	G0RNL3_HYPJQ	G0R842	G0RNL3	Dehydratase.	Isopropylmalate/homocitrate/citramalate synthase.	0.961
G0R842_HYPJQ	G0RQR9_HYPJQ	G0R842	G0RQR9	Dehydratase.	Dehydratase family.	0.911
G0R842_HYPJQ	G0RSU4_HYPJQ	G0R842	G0RSU4	Dehydratase.	Homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family.	0.629
G0R842_HYPJQ	G0RTE6_HYPJQ	G0R842	G0RTE6	Dehydratase.	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family.	0.934
G0R842_HYPJQ	G0RTT9_HYPJQ	G0R842	G0RTT9	Dehydratase.	Predicted protein.	0.404
G0R842_HYPJQ	G0RUQ0_HYPJQ	G0R842	G0RUQ0	Dehydratase.	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.968
G0R842_HYPJQ	G0RWK5_HYPJQ	G0R842	G0RWK5	Dehydratase.	Beta-isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.	0.410
G0R842_HYPJQ	idh2	G0R842	G0RA51	Dehydratase.	Isocitrate dehydrogenase [NAD] subunit, mitochondrial.	0.404
G0R861_HYPJQ	G0R842_HYPJQ	G0R861	G0R842	Small regulatory subunit of acetolactate synthase.	Dehydratase.	0.673
G0R861_HYPJQ	G0R8N2_HYPJQ	G0R861	G0R8N2	Small regulatory subunit of acetolactate synthase.	Acetolactate synthase.	0.999
G0R861_HYPJQ	G0RA60_HYPJQ	G0R861	G0RA60	Small regulatory subunit of acetolactate synthase.	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.	0.943