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AND_007815 AND_007815 AND_001151 AND_001151 ND2 ND2 COX1 COX1 COX2 COX2 ATP6 ATP6 COX3 COX3 ND3 ND3 ND5 ND5 ND4 ND4 ND4L ND4L CYTB CYTB ND1 ND1 AND_006288 AND_006288 AND_010493 AND_010493 AND_010637 AND_010637 AND_010040 AND_010040 AND_010241 AND_010241 AND_010086 AND_010086 AND_009762 AND_009762 AND_010268 AND_010268 AND_008921 AND_008921 AND_010546 AND_010546 AND_009977 AND_009977 AND_008448 AND_008448 AND_008439 AND_008439 AND_009798 AND_009798 AND_009744 AND_009744 AND_008548 AND_008548 AND_009633 AND_009633 AND_009049 AND_009049 AND_007604 AND_007604 AND_009283 AND_009283 AND_008617 AND_008617 AND_007843 AND_007843 AND_008905 AND_008905 AND_008425 AND_008425 AND_007054 AND_007054 AND_006974 AND_006974 AND_006641 AND_006641 AND_006289 AND_006289 AND_007700 AND_007700 AND_005978 AND_005978 AND_006938 AND_006938 AND_006107 AND_006107 AND_006785 AND_006785 AND_005976 AND_005976 AND_005498 AND_005498 AND_006966 AND_006966 AND_006936 AND_006936 AND_006810 AND_006810 AND_006754 AND_006754 AND_006685 AND_006685 AND_006592 AND_006592 AND_006180 AND_006180 AND_005997 AND_005997 AND_005582 AND_005582 AND_005575 AND_005575 AND_005555 AND_005555 AND_005864 AND_005864 AND_004520 AND_004520 AND_005919 AND_005919 AND_004433 AND_004433 AND_003839 AND_003839 AND_003865 AND_003865 AND_005090 AND_005090 AND_003553 AND_003553 AND_003329 AND_003329 AND_004138 AND_004138 AND_003257 AND_003257 AND_002854 AND_002854 AND_002590 AND_002590 AND_003656 AND_003656 AND_004172 AND_004172 AND_002488 AND_002488 AND_003975 AND_003975 AND_003911 AND_003911 AND_003811 AND_003811 AND_002442 AND_002442 AND_002393 AND_002393 AND_002332 AND_002332 AND_002054 AND_002054 AND_003551 AND_003551 AND_002226 AND_002226 AND_003578 AND_003578 AND_002115 AND_002115 AND_001840 AND_001840 AND_001808 AND_001808 AND_002585 AND_002585 AND_001153 AND_001153 AND_002747 AND_002747 AND_001034 AND_001034 AND_001155 AND_001155 AND_001813 AND_001813 AND_001995 AND_001995 AND_001997 AND_001997 AND_001677 AND_001677 AND_001458 AND_001458 AND_001456 AND_001456 AND_001580 AND_001580 AND_001050 AND_001050 AND_000070 AND_000070
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
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AND_007815ATP synthase-coupling factor 6, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain; Belongs to the eukaryotic ATPase subunit F6 family. (107 aa)
AND_001151NADH ubiquinone dehydrogenase. (83 aa)
ND2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (341 aa)
COX1Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (512 aa)
COX2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (228 aa)
ATP6ATP synthase subunit a. (226 aa)
COX3Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (262 aa)
ND3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (117 aa)
ND5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (580 aa)
ND4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (447 aa)
ND4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (99 aa)
CYTBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (378 aa)
ND1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa)
AND_006288ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (503 aa)
AND_010493Uncharacterized protein. (155 aa)
AND_010637NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (143 aa)
AND_010040NADH dehydrogenase flavoprotein 2, mitochondrial. (239 aa)
AND_010241NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa)
AND_010086Putative cell death-regulatory protein grim19. (151 aa)
AND_009762Cytochrome b-c1 complex subunit 6; This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. This protein may mediate formation of the complex between cytochromes c and c1. Belongs to the UQCRH/QCR6 family. (87 aa)
AND_010268Mitochondrial ATPase inhibitor. (105 aa)
AND_008921ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (551 aa)
AND_010546Inorganic pyrophosphatase. (344 aa)
AND_009977Cytochrome c proximal; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
AND_008448ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (182 aa)
AND_008439NADH:ubiquinone dehydrogenase; Belongs to the complex I LYR family. (156 aa)
AND_009798Mitochondrial NADH dehydrogenase Fe-S protein. (101 aa)
AND_009744NAD(P)-bd_dom domain-containing protein. (202 aa)
AND_008548NADH dehydrogenase. (125 aa)
AND_009633NADH-ubiquinone oxidoreductase B8 subunit. (97 aa)
AND_009049Cytochrome c oxidase polypeptide. (157 aa)
AND_007604FAD oxidoreductase. (526 aa)
AND_009283ATP synthase B chain, mitochondrial. (237 aa)
AND_008617NADH-ubiquinone oxidoreductase ashi subunit. (175 aa)
AND_007843Uncharacterized protein. (273 aa)
AND_008905Uncharacterized protein. (2561 aa)
AND_008425Mitochondrial processing peptidase alpha subunit; Belongs to the peptidase M16 family. (548 aa)
AND_007054Mitochondrial cytochrome c oxidase subunit VIC. (79 aa)
AND_006974Transmembrane protein 70. (235 aa)
AND_006641WW domain-binding protein 2. (315 aa)
AND_006289ATP-synt_ab_N domain-containing protein. (250 aa)
AND_007700ATP synthase subunit; Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proto [...] (99 aa)
AND_005978Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (76 aa)
AND_006938Zinc finger protein. (67 aa)
AND_006107NADH-ubiquinone oxidoreductase 39 kDa subunit. (401 aa)
AND_006785Eukaryotic translation initiation factor 4E binding protein (4EBP). (215 aa)
AND_005976Uncharacterized protein. (423 aa)
AND_005498Ecsit (Evolutionarily conserved signaling intermediate in toll pathways). (395 aa)
AND_006966Protein arginine methyltransferase NDUFAF7; Arginine methyltransferase involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). (476 aa)
AND_006936Uncharacterized protein. (170 aa)
AND_006810Cytochrome c oxidase, subunit VB. (119 aa)
AND_006754Uncharacterized protein. (225 aa)
AND_006685NADH dehydrogenase 1 alpha subcomplex subunit 5. (154 aa)
AND_006592Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (158 aa)
AND_006180NADH dehydrogenase; Belongs to the complex I LYR family. (124 aa)
AND_005997Uncharacterized protein. (189 aa)
AND_005582Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (268 aa)
AND_005575RPII140-upstream protein. (315 aa)
AND_005555NADH dehydrogenase iron-sulfur protein 8, mitochondrial. (217 aa)
AND_005864Uncharacterized protein. (88 aa)
AND_004520NADH-plastoquinone oxidoreductase; Belongs to the complex I 20 kDa subunit family. (210 aa)
AND_005919Uncharacterized protein. (149 aa)
AND_004433NADH-ubiquinone oxidoreductase fe-s protein 2 (Ndufs2); Belongs to the complex I 49 kDa subunit family. (473 aa)
AND_003839THAP-type domain-containing protein. (508 aa)
AND_003865NADH dehydrogenase. (100 aa)
AND_005090Mitochondrial NADH:ubiquinone oxidoreductase ESSS subunit. (152 aa)
AND_003553ATP synthase subunit d, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the cent [...] (172 aa)
AND_003329NADH-ubiquinone oxidoreductase; Belongs to the complex I 75 kDa subunit family. (730 aa)
AND_004138Phospholysine phosphohistidine inorganic pyrophosphate phosphatase. (307 aa)
AND_003257Chaperone protein. (336 aa)
AND_002854Low molecular mass ubiquinone-binding protein. (82 aa)
AND_002590Oxidoreductase. (630 aa)
AND_003656Mitochondrial NADH-ubiquinone oxidoreductase AGGG subunit. (104 aa)
AND_004172NADH:ubiquinone dehydrogenase. (180 aa)
AND_0024886.3 kDa salivary peptide. (70 aa)
AND_003975Ubiquinol-cytochrome c reductase complex core protein. (439 aa)
AND_003911Mitochondrial processing peptidase beta subunit; Belongs to the peptidase M16 family. (475 aa)
AND_003811Putative cytochrome c oxidase subunit 7A, mitochondrial. (74 aa)
AND_002442NADH-ubiquinone oxidoreductase sgdh subunit. (189 aa)
AND_002393ATP synthase subunit gamma. (297 aa)
AND_002332Uncharacterized protein. (87 aa)
AND_002054NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (125 aa)
AND_003551NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (395 aa)
AND_002226Mitochondrial processing peptidase beta subunit. (511 aa)
AND_003578NADH:ubiquinone dehydrogenase. (107 aa)
AND_002115Ubiquinol cytochrome C oxidoreductase-subunit 6.4kD-subunit. (55 aa)
AND_001840Uncharacterized protein. (91 aa)
AND_001808Mitochondrial ATP synthase lipid binding protein; Belongs to the ATPase C chain family. (138 aa)
AND_002585Mitochondrial ATP synthase F chain. (107 aa)
AND_001153ATP synthase subunit epsilon, mitochondrial. (61 aa)
AND_002747Cytochrome c oxidase subunit VIIa. (89 aa)
AND_001034NADH dehydrogenase [ubiquinone] 1 subunit C2; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (114 aa)
AND_001155NADH dehydrogenase iron-sulfur protein 3, mitochondrial; Belongs to the complex I 30 kDa subunit family. (264 aa)
AND_001813Cytochrome c oxidase, subunit VIA; Belongs to the cytochrome c oxidase subunit 6A family. (148 aa)
AND_001995Methyltransf_11 domain-containing protein. (332 aa)
AND_001997Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (110 aa)
AND_001677ATP-synt_C domain-containing protein; Belongs to the ATPase C chain family. (135 aa)
AND_001458Lethal 35Di. (163 aa)
AND_001456Cytochrome c oxidase subunit iv. (202 aa)
AND_001580Cytochrome C1. (307 aa)
AND_001050NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (489 aa)
AND_000070ATP synthase delta chain, mitochondrial. (159 aa)
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
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