8 items (Anopheles darlingi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_010578	Metastasis-associated protein MTA. (945 aa)
	AND_009033	Uncharacterized protein. (674 aa)
	AND_010092	Lysine-specific histone demethylase. (921 aa)
	AND_009867	Methyl-cpg binding protein, mbd. (316 aa)
	AND_006680	P66_CC domain-containing protein. (845 aa)
	AND_004775	REST corepressor. (626 aa)
	AND_001486	Chromodomain helicase DNA binding protein. (2227 aa)
	AND_000362	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1180 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000362	AND_001486	W5JUI4	W5JRF8	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Chromodomain helicase DNA binding protein.	0.795
AND_000362	AND_004775	W5JUI4	W5JJN4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	REST corepressor.	0.852
AND_000362	AND_006680	W5JUI4	W5JB16	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	P66_CC domain-containing protein.	0.723
AND_000362	AND_009033	W5JUI4	W5J5V7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Uncharacterized protein.	0.751
AND_000362	AND_009867	W5JUI4	W5J6U8	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Methyl-cpg binding protein, mbd.	0.854
AND_000362	AND_010092	W5JUI4	W5J634	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Lysine-specific histone demethylase.	0.847
AND_000362	AND_010578	W5JUI4	W5J4W5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Metastasis-associated protein MTA.	0.846
AND_001486	AND_000362	W5JRF8	W5JUI4	Chromodomain helicase DNA binding protein.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.795
AND_001486	AND_004775	W5JRF8	W5JJN4	Chromodomain helicase DNA binding protein.	REST corepressor.	0.937
AND_001486	AND_006680	W5JRF8	W5JB16	Chromodomain helicase DNA binding protein.	P66_CC domain-containing protein.	0.984
AND_001486	AND_009867	W5JRF8	W5J6U8	Chromodomain helicase DNA binding protein.	Methyl-cpg binding protein, mbd.	0.983
AND_001486	AND_010092	W5JRF8	W5J634	Chromodomain helicase DNA binding protein.	Lysine-specific histone demethylase.	0.929
AND_001486	AND_010578	W5JRF8	W5J4W5	Chromodomain helicase DNA binding protein.	Metastasis-associated protein MTA.	0.986
AND_004775	AND_000362	W5JJN4	W5JUI4	REST corepressor.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.852
AND_004775	AND_001486	W5JJN4	W5JRF8	REST corepressor.	Chromodomain helicase DNA binding protein.	0.937
AND_004775	AND_006680	W5JJN4	W5JB16	REST corepressor.	P66_CC domain-containing protein.	0.686
AND_004775	AND_009033	W5JJN4	W5J5V7	REST corepressor.	Uncharacterized protein.	0.929
AND_004775	AND_009867	W5JJN4	W5J6U8	REST corepressor.	Methyl-cpg binding protein, mbd.	0.760
AND_004775	AND_010092	W5JJN4	W5J634	REST corepressor.	Lysine-specific histone demethylase.	0.993
AND_004775	AND_010578	W5JJN4	W5J4W5	REST corepressor.	Metastasis-associated protein MTA.	0.708