(52 nodes) Mixed, incl. Protein tyrosine kinase activity, and Protein tyrosine kinase binding network (Anopheles darlingi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_010197	Tyrosine-protein kinase. (691 aa)
	AND_010176	Signal transducer and activator of transcription. (928 aa)
	AND_009206	Titin. (8216 aa)
	AND_008762	Tyrosine-protein kinase transmembrane receptor Ror2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (701 aa)
	AND_009234	Uncharacterized protein. (910 aa)
	AND_010295	Receptor protein tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (807 aa)
	AND_009486	IRS-type PTB domain-containing protein. (751 aa)
	AND_009230	Ras GTP exchange factor. (505 aa)
	AND_009681	Signal transduction protein lnk-realted. (711 aa)
	AND_007123	Tyrosine-protein kinase receptor. (1229 aa)
	AND_007490	Protein tyrosine phosphatase n11 (Shp2). (823 aa)
	AND_007380	Tyrosine-protein kinase. (537 aa)
	AND_008414	Putative ras-related gtpase. (189 aa)
	AND_007698	Crk. (278 aa)
	AND_005865	Uncharacterized protein. (2101 aa)
	AND_005827	Ras GTP exchange factor, son of sevenless. (1869 aa)
	AND_006400	Insulin receptor. (1096 aa)
	AND_006817	Insulin-like peptide 2. (147 aa)
	AND_006699	Stretchin-mlck. (2840 aa)
	AND_006094	Cbl-d. (182 aa)
	AND_006538	Dab2-interacting protein. (1134 aa)
	AND_005231	Receptor protein-tyrosine kinase. (1494 aa)
	AND_005922	Uncharacterized protein. (827 aa)
	AND_005048	Tyrosine-protein kinase receptor. (1592 aa)
	AND_006235	Guanylate cyclase. (1468 aa)
	AND_006349	IRS-type PTB domain-containing protein. (533 aa)
	AND_004966	Uncharacterized protein. (1562 aa)
	AND_003939	Guanine nucleotide-releasing factor 2. (497 aa)
	AND_003474	Tyrosine-protein kinase. (496 aa)
	AND_003471	Uncharacterized protein. (1303 aa)
	AND_004694	Uncharacterized protein. (291 aa)
	AND_004656	Uncharacterized protein. (768 aa)
	AND_004635	Uncharacterized protein. (580 aa)
	AND_003475	Uncharacterized protein. (1340 aa)
	AND_003418	Cell adhesion molecule. (2798 aa)
	AND_002482	Scavenger receptor class A-like, serine protease; Belongs to the peptidase S1 family. (211 aa)
	AND_003619	Uncharacterized protein. (2150 aa)
	AND_002111	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1507 aa)
	AND_003395	Tyrosine-protein kinase receptor. (931 aa)
	AND_001767	Uncharacterized protein. (1851 aa)
	AND_002478	Scavenger receptor class A-like, serine protease. (1222 aa)
	AND_002117	Tyrosine phosphatase, non-receptor type nt1. (757 aa)
	AND_001760	Unc-89 protein. (5569 aa)
	AND_000740	Proto-oncogene tyrosine-protein kinase ROS. (1727 aa)
	AND_000733	Jak kinase hopscotch. (337 aa)
	AND_001557	Shc transforming protein. (138 aa)
	AND_001548	Shc transforming protein. (307 aa)
	AND_000118	Uncharacterized protein. (1139 aa)
	AND_000930	Grb2-associated binder, gab. (894 aa)
	AND_000681	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (656 aa)
	AND_000745	Uncharacterized protein. (775 aa)
	AND_000609	Growth factor receptor-bound protein. (178 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000118	AND_000681	W5JV63	W5JWD1	Uncharacterized protein.	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.810
AND_000118	AND_000733	W5JV63	W5JTK4	Uncharacterized protein.	Jak kinase hopscotch.	0.850
AND_000118	AND_001760	W5JV63	W5JT47	Uncharacterized protein.	Unc-89 protein.	0.758
AND_000118	AND_002111	W5JV63	W5JPQ3	Uncharacterized protein.	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.807
AND_000118	AND_003418	W5JV63	W5JND2	Uncharacterized protein.	Cell adhesion molecule.	0.537
AND_000118	AND_003471	W5JV63	W5JKV7	Uncharacterized protein.	Uncharacterized protein.	0.612
AND_000118	AND_003474	W5JV63	W5JK69	Uncharacterized protein.	Tyrosine-protein kinase.	0.501
AND_000118	AND_003475	W5JV63	W5JN82	Uncharacterized protein.	Uncharacterized protein.	0.501
AND_000118	AND_003619	W5JV63	W5JP08	Uncharacterized protein.	Uncharacterized protein.	0.451
AND_000118	AND_004694	W5JV63	W5JKZ8	Uncharacterized protein.	Uncharacterized protein.	0.694
AND_000118	AND_005231	W5JV63	W5JG62	Uncharacterized protein.	Receptor protein-tyrosine kinase.	0.541
AND_000118	AND_007380	W5JV63	W5JAG1	Uncharacterized protein.	Tyrosine-protein kinase.	0.501
AND_000118	AND_007490	W5JV63	W5JA53	Uncharacterized protein.	Protein tyrosine phosphatase n11 (Shp2).	0.569
AND_000118	AND_009206	W5JV63	W5J457	Uncharacterized protein.	Titin.	0.797
AND_000118	AND_010176	W5JV63	W5J1W2	Uncharacterized protein.	Signal transducer and activator of transcription.	0.871
AND_000609	AND_000681	W5JWU5	W5JWD1	Growth factor receptor-bound protein.	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.767
AND_000609	AND_000733	W5JWU5	W5JTK4	Growth factor receptor-bound protein.	Jak kinase hopscotch.	0.767
AND_000609	AND_000740	W5JWU5	W5JTJ9	Growth factor receptor-bound protein.	Proto-oncogene tyrosine-protein kinase ROS.	0.971
AND_000609	AND_000745	W5JWU5	W5JWP5	Growth factor receptor-bound protein.	Uncharacterized protein.	0.748
AND_000609	AND_000930	W5JWU5	W5JVY8	Growth factor receptor-bound protein.	Grb2-associated binder, gab.	0.996