18 items (Anopheles darlingi) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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Predicted Interactions

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Your Input:
	AND_010608	FACT complex subunit spt16. (1081 aa)
	AND_010187	Transcription elongation factor SPT5. (1089 aa)
	AND_009402	Antimeros. (555 aa)
	AND_008839	Another transcription unit protein. (643 aa)
	AND_008215	DNA-directed RNA polymerase II subunit J. (117 aa)
	AND_008600	TPR repeat-containing protein. (1234 aa)
	AND_007407	Cdc73 domain protein. (544 aa)
	AND_007401	DNA-directed RNA polymerase II 19 kDa polypeptide. (173 aa)
	AND_005046	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
	AND_006582	DNA-directed RNA polymerase subunit rpb6. (131 aa)
	AND_005336	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (116 aa)
	AND_005115	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (730 aa)
	AND_003778	DNA-directed RNA polymerase II subunit. (273 aa)
	AND_005224	Transcription elongation factor s-ii. (332 aa)
	AND_001836	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (127 aa)
	AND_001853	RNA polymerase-associated protein Rtf1. (673 aa)
	AND_000616	DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
	AND_000842	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1880 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000616	AND_000842	W5JT59	W5JT78	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
AND_000616	AND_001836	W5JT59	W5JPR2	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.999
AND_000616	AND_001853	W5JT59	W5JQG2	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	RNA polymerase-associated protein Rtf1.	0.907
AND_000616	AND_003778	W5JT59	W5JJD1	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase II subunit.	0.999
AND_000616	AND_005046	W5JT59	W5JFU4	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.999
AND_000616	AND_005115	W5JT59	W5JIR0	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]	0.977
AND_000616	AND_005224	W5JT59	W5JJW7	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	Transcription elongation factor s-ii.	0.990
AND_000616	AND_005336	W5JT59	W5JFX8	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family.	0.992
AND_000616	AND_006582	W5JT59	W5JFU5	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase subunit rpb6.	0.999
AND_000616	AND_007401	W5JT59	W5JCB3	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase II 19 kDa polypeptide.	0.999
AND_000616	AND_007407	W5JT59	W5J929	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	Cdc73 domain protein.	0.952
AND_000616	AND_008215	W5JT59	W5J6V9	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	DNA-directed RNA polymerase II subunit J.	0.999
AND_000616	AND_008600	W5JT59	W5J743	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	TPR repeat-containing protein.	0.959
AND_000616	AND_008839	W5JT59	W5J6D6	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	Another transcription unit protein.	0.949
AND_000616	AND_009402	W5JT59	W5J4X5	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	Antimeros.	0.955
AND_000616	AND_010187	W5JT59	W5J4B3	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	Transcription elongation factor SPT5.	0.991
AND_000616	AND_010608	W5JT59	W5J3B2	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	FACT complex subunit spt16.	0.976
AND_000842	AND_000616	W5JT78	W5JT59	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerases I, II, and III subunit RPABC5.	0.999
AND_000842	AND_001836	W5JT78	W5JPR2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.999
AND_000842	AND_001853	W5JT78	W5JQG2	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	RNA polymerase-associated protein Rtf1.	0.935