STRINGSTRING
AND_008837 AND_008837 AND_000403 AND_000403 AND_000072 AND_000072 AND_000382 AND_000382 AND_000546 AND_000546 AND_002244 AND_002244 AND_002669 AND_002669 AND_001300 AND_001300 AND_002809 AND_002809 AND_003066 AND_003066 AND_002597 AND_002597 AND_002379 AND_002379 AND_004822 AND_004822 AND_005352 AND_005352 AND_006224 AND_006224 AND_005572 AND_005572 PIF1 PIF1 AND_008178 AND_008178 AND_008059 AND_008059 AND_007678 AND_007678
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AND_008837FHA domain-containing protein. (720 aa)
AND_000403Checkpoint protein; Belongs to the HUS1 family. (294 aa)
AND_000072S6 kinase II beta. (329 aa)
AND_000382DNA ligase 4; Belongs to the ATP-dependent DNA ligase family. (954 aa)
AND_000546Uncharacterized protein. (116 aa)
AND_002244Ku domain-containing protein. (583 aa)
AND_002669Uncharacterized protein. (102 aa)
AND_001300Rif1_N domain-containing protein. (1970 aa)
AND_002809DNA cross-link repair 1A protein. (757 aa)
AND_003066Regulator of telomere elongation helicase 1 homolog; ATP-dependent DNA helicase implicated in DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. (1010 aa)
AND_002597FATC domain-containing protein. (1231 aa)
AND_002379Ku P80 DNA helicase. (728 aa)
AND_004822Spindle-b recombination protein spn-b. (273 aa)
AND_005352NUC194 domain-containing protein. (2413 aa)
AND_006224DNA repair protein RAD50. (1309 aa)
AND_005572Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (621 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (680 aa)
AND_008178Uncharacterized protein. (910 aa)
AND_008059Peptidase C50 domain-containing protein. (595 aa)
AND_007678Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3165 aa)
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
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