STRINGSTRING
AND_005522 AND_005522 AND_004958 AND_004958 AND_005319 AND_005319 AND_003785 AND_003785 AND_005218 AND_005218 AND_004803 AND_004803 AND_004775 AND_004775 AND_003609 AND_003609 AND_004964 AND_004964 AND_004895 AND_004895 AND_003347 AND_003347 AND_004544 AND_004544 AND_003184 AND_003184 AND_002930 AND_002930 AND_004549 AND_004549 MED8 MED8 AND_003027 AND_003027 AND_002980 AND_002980 AND_004378 AND_004378 AND_003797 AND_003797 AND_002683 AND_002683 MED20 MED20 AND_002538 AND_002538 Sgf11 Sgf11 AND_004004 AND_004004 AND_002353 AND_002353 MED8-2 MED8-2 AND_003381 AND_003381 AND_002267 AND_002267 AND_003756 AND_003756 AND_003732 AND_003732 MED18 MED18 AND_003713 AND_003713 AND_003659 AND_003659 AND_003060 AND_003060 AND_001955 AND_001955 AND_002957 AND_002957 AND_003346 AND_003346 AND_003351 AND_003351 AND_003379 AND_003379 AND_001953 AND_001953 AND_003225 AND_003225 AND_001775 AND_001775 MED9 MED9 AND_002951 AND_002951 AND_002355 AND_002355 AND_002920 AND_002920 AND_001111 AND_001111 AND_002249 AND_002249 AND_001388 AND_001388 AND_002242 AND_002242 MED10 MED10 AND_002419 AND_002419 AND_001179 AND_001179 AND_001138 AND_001138 AND_002481 AND_002481 AND_000832 AND_000832 AND_001055 AND_001055 AND_002265 AND_002265 AND_002238 AND_002238 AND_000646 AND_000646 AND_001384 AND_001384 AND_000288 AND_000288 AND_000274 AND_000274 AND_001263 AND_001263 AND_001759 AND_001759 AND_001466 AND_001466 AND_000934 AND_000934 AND_001413 AND_001413 AND_000726 AND_000726 AND_001274 AND_001274 AND_001215 AND_001215 AND_001148 AND_001148 AND_001065 AND_001065 AND_001026 AND_001026 AND_001008 AND_001008 AND_000628 AND_000628 AND_000071 AND_000071 e(y)2 e(y)2 AND_000365 AND_000365 AND_000525 AND_000525 AND_000276 AND_000276 AND_006039 AND_006039 AND_007154 AND_007154 AND_007165 AND_007165 AND_007921 AND_007921 AND_006641 AND_006641 AND_006774 AND_006774 AND_008080 AND_008080 MED19 MED19 AND_008327 AND_008327 AND_008240 AND_008240 AND_007865 AND_007865 AND_006842 AND_006842 AND_007352 AND_007352 AND_007392 AND_007392 AND_007441 AND_007441 AND_008615 AND_008615 AND_008712 AND_008712 AND_008830 AND_008830 AND_008155 AND_008155 AND_007198 AND_007198 AND_008315 AND_008315 AND_008329 AND_008329 MED11 MED11 AND_007506 AND_007506 AND_009141 AND_009141 AND_009294 AND_009294 AND_007548 AND_007548 AND_007918 AND_007918 AND_009093 AND_009093 AND_009757 AND_009757 AND_009734 AND_009734 AND_009903 AND_009903 AND_009244 AND_009244 AND_009867 AND_009867 AND_009917 AND_009917 AND_010013 AND_010013 AND_009383 AND_009383 AND_009982 AND_009982 AND_009490 AND_009490 AND_010062 AND_010062 AND_008496 AND_008496 AND_009562 AND_009562 AND_010114 AND_010114 AND_009048 AND_009048 AND_010312 AND_010312 AND_010447 AND_010447 AND_010381 AND_010381 AND_009913 AND_009913 AND_010578 AND_010578 AND_008878 AND_008878 AND_010550 AND_010550 AND_010294 AND_010294 AND_009248 AND_009248 AND_009894 AND_009894 AND_009919 AND_009919 AND_009487 AND_009487 AND_009986 AND_009986 AND_010386 AND_010386 AND_010562 AND_010562 MED15 MED15 AND_007006 AND_007006 AND_006983 AND_006983 AND_005889 AND_005889 AND_006807 AND_006807 AND_005431 AND_005431 AND_006902 AND_006902 AND_005232 AND_005232 AND_005049 AND_005049 AND_006334 AND_006334 MED4 MED4 MED17 MED17 AND_006339 AND_006339 AND_005618 AND_005618 AND_005560 AND_005560 AND_005874 AND_005874 AND_005795 AND_005795 AND_004137 AND_004137 AND_005233 AND_005233 AND_004030 AND_004030 AND_004139 AND_004139
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AND_005522Uncharacterized protein. (968 aa)
AND_004958Uncharacterized protein. (127 aa)
AND_005319Period circadian protein. (1751 aa)
AND_003785Uncharacterized protein. (1466 aa)
AND_005218Nervy. (618 aa)
AND_0048032-hydroxyacid dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (411 aa)
AND_004775REST corepressor. (626 aa)
AND_003609Lim domain binding protein. (746 aa)
AND_004964Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (3188 aa)
AND_004895ANK_REP_REGION domain-containing protein. (4109 aa)
AND_003347Four and a half lim. (290 aa)
AND_004544Cysteine-rich protein. (179 aa)
AND_003184Groucho protein (Enhancer of split). (581 aa)
AND_002930Fibronectin type-III domain-containing protein. (1278 aa)
AND_004549Uncharacterized protein. (2182 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (256 aa)
AND_003027LIM zinc-binding domain-containing protein. (297 aa)
AND_002980P160 coactivator FISC. (2091 aa)
AND_004378Ornithine cyclodeaminase. (370 aa)
AND_003797Uncharacterized protein. (898 aa)
AND_002683PHD-type domain-containing protein. (2652 aa)
MED20Mediator of RNA polymerase II transcription subunit 20; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (219 aa)
AND_002538Groucho protein. (685 aa)
Sgf11SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. (180 aa)
AND_004004Brg-1 associated factor. (508 aa)
AND_002353Mesoderm induction early response protein 1. (357 aa)
MED8-2Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (247 aa)
AND_003381Yorkie. (536 aa)
AND_002267Uncharacterized protein. (511 aa)
AND_003756Brg-1 associated factor. (536 aa)
AND_003732Wd-repeat protein. (504 aa)
MED18Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (211 aa)
AND_003713Uncharacterized protein. (827 aa)
AND_003659Notch. (2296 aa)
AND_003060Big brother. (267 aa)
AND_001955Uncharacterized protein. (150 aa)
AND_002957SANT domain-containing protein. (678 aa)
AND_003346Four and a half lim. (286 aa)
AND_003351Uncharacterized protein. (271 aa)
AND_003379Thyroid hormone receptor-associated protein complex 100 kDa component. (1034 aa)
AND_001953Transcription initiation factor TFIID subunit 11. (213 aa)
AND_003225Sap30. (174 aa)
AND_001775Thyroid hormone receptor-associated protein 6. (325 aa)
MED9Mediator of RNA polymerase II transcription subunit 9; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (110 aa)
AND_002951LIM zinc-binding domain-containing protein. (229 aa)
AND_002355Mothers against decapentaplegic homolog. (541 aa)
AND_002920Uncharacterized protein. (434 aa)
AND_001111Cop9 signalosome complex subunit. (445 aa)
AND_002249DEAD box ATP-dependent RNA helicase. (728 aa)
AND_001388Uncharacterized protein. (83 aa)
AND_002242Nnp-1 protein. (741 aa)
MED10Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (130 aa)
AND_002419Sumo ligase. (1238 aa)
AND_001179Growth and transformation-dependent protein. (157 aa)
AND_001138RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (482 aa)
AND_002481Activating signal cointegrator 1. (554 aa)
AND_000832RanBP2-type domain-containing protein. (151 aa)
AND_001055Mediator of RNA polymerase II transcription subunit 6. (263 aa)
AND_002265Uncharacterized protein. (396 aa)
AND_002238JmjC domain-containing protein. (1452 aa)
AND_000646Uncharacterized protein. (3131 aa)
AND_001384Requim, req/dpf2. (539 aa)
AND_000288Uncharacterized protein. (500 aa)
AND_000274Sorting nexin. (1785 aa)
AND_001263Med1 domain-containing protein. (2224 aa)
AND_001759Uncharacterized protein. (168 aa)
AND_001466Proliferation-associated 2g4. (422 aa)
AND_000934DNA methyltransferase 1-associated protein 1. (443 aa)
AND_001413Uncharacterized protein. (267 aa)
AND_000726Mediator complex. (295 aa)
AND_001274Uncharacterized protein. (2771 aa)
AND_001215Suppressor of ty3. (322 aa)
AND_001148RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (456 aa)
AND_001065Uncharacterized protein. (575 aa)
AND_001026Transcriptional adapter. (522 aa)
AND_001008Cir_N domain-containing protein. (215 aa)
AND_000628RrnaAD, ribosomal rRNA adenine dimethylase. (487 aa)
AND_000071CBF domain-containing protein. (1036 aa)
e(y)2Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (93 aa)
AND_000365Cell division cycle and apoptosis regulator protein 1. (1384 aa)
AND_000525Uncharacterized protein. (199 aa)
AND_000276BZIP domain-containing protein. (378 aa)
AND_006039F-box domain-containing protein. (434 aa)
AND_007154Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (302 aa)
AND_007165Lipin-3. (1179 aa)
AND_007921BRCT domain-containing protein. (1412 aa)
AND_006641WW domain-binding protein 2. (315 aa)
AND_006774WD_REPEATS_REGION domain-containing protein. (405 aa)
AND_008080Mediator complex. (138 aa)
MED19Mediator of RNA polymerase II transcription subunit 19; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (252 aa)
AND_008327Uncharacterized protein. (115 aa)
AND_008240Uncharacterized protein. (4309 aa)
AND_007865BTG1 protein. (228 aa)
AND_006842Limd1. (925 aa)
AND_007352TLE_N domain-containing protein. (136 aa)
AND_007392Protein kinase domain-containing protein. (1003 aa)
AND_007441SAP domain-containing protein. (1268 aa)
AND_008615Transcription initiation factor TFIID subunit 9. (274 aa)
AND_008712SNR1. (369 aa)
AND_008830DNA polymerase v. (1264 aa)
AND_008155Sin3b. (2132 aa)
AND_007198Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (826 aa)
AND_008315Mixed-lineage leukemia protein. (7728 aa)
AND_008329Cuticular protein 5 from Low Complexity family. (146 aa)
MED11Mediator of RNA polymerase II transcription subunit 11; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (134 aa)
AND_007506Heat shock factor binding protein. (84 aa)
AND_009141Calphotin. (131 aa)
AND_009294Intersex. (205 aa)
AND_007548Myb-like domain-containing protein. (1687 aa)
AND_007918Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1642 aa)
AND_009093Daxx-like protein. (665 aa)
AND_009757Mediator of RNA polymerase II transcription subunit 21; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (138 aa)
AND_009734Mediator complex. (251 aa)
AND_009903Uncharacterized protein. (517 aa)
AND_009244Chromatin regulatory protein sir2. (556 aa)
AND_009867Methyl-cpg binding protein, mbd. (316 aa)
AND_009917Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
AND_010013POU domain protein. (265 aa)
AND_009383Thyroid hormone receptor-associated protein. (2837 aa)
AND_009982Uncharacterized protein. (2596 aa)
AND_009490Hepatoma-derived GF. (429 aa)
AND_010062Uncharacterized protein. (1841 aa)
AND_008496Chromatin regulatory protein sir2. (353 aa)
AND_009562Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (335 aa)
AND_010114Cabeza. (412 aa)
AND_009048Uncharacterized protein. (179 aa)
AND_010312Uncharacterized protein. (343 aa)
AND_010447Uncharacterized protein. (103 aa)
AND_010381Transcription initiation factor TFIID subunit 6. (669 aa)
AND_009913Autoimmune regulator. (708 aa)
AND_010578Metastasis-associated protein MTA. (945 aa)
AND_008878Host cell factor. (1888 aa)
AND_010550Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. (219 aa)
AND_010294Uncharacterized protein. (188 aa)
AND_009248Uncharacterized protein. (882 aa)
AND_009894Coiled-coil domain-containing protein 124. (212 aa)
AND_009919Uncharacterized protein. (500 aa)
AND_009487Hepatoma-derived GF. (471 aa)
AND_009986F-box and leucine-rich repeat protein 11. (1422 aa)
AND_010386SPT3-associated factor 42. (320 aa)
AND_010562Alpha-aminoadipic semialdehyde synthase, mitochondrial. (930 aa)
MED15Mediator of RNA polymerase II transcription subunit 15; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1026 aa)
AND_007006RRM domain-containing protein. (1732 aa)
AND_006983ARID domain-containing protein. (1545 aa)
AND_005889Noc2l protein. (888 aa)
AND_006807Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (807 aa)
AND_005431Prohibitin. (272 aa)
AND_006902Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (491 aa)
AND_005232Uncharacterized protein. (1687 aa)
AND_005049Uncharacterized protein. (2129 aa)
AND_006334Uncharacterized protein. (522 aa)
MED4Mediator of RNA polymerase II transcription subunit 4; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (265 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (645 aa)
AND_006339p31A. (105 aa)
AND_005618CRSP complex subunit 3. (1474 aa)
AND_005560Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (149 aa)
AND_005874Uncharacterized protein. (468 aa)
AND_005795SRA1 domain-containing protein. (219 aa)
AND_004137Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (523 aa)
AND_005233Mediator of RNA polymerase II transcription subunit 13; Component of the Mediator complex, a coactivator involved in regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1257 aa)
AND_004030Paxillin. (230 aa)
AND_004139Calmodulin-binding transcription activator (Camta), drome. (1999 aa)
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
Server load: low (22%) [HD]