STRINGSTRING
AND_008458 AND_008458 AND_010209 AND_010209 AND_009607 AND_009607 AND_010478 AND_010478 AND_009634 AND_009634 AND_009254 AND_009254 AND_009880 AND_009880 AND_010372 AND_010372 AND_010064 AND_010064 AND_000887 AND_000887 AND_001430 AND_001430 AND_000092 AND_000092 AND_001366 AND_001366 AND_001632 AND_001632 AND_001484 AND_001484 AND_001581 AND_001581 AND_000382 AND_000382 AND_001838 AND_001838 AND_001356 AND_001356 AND_000716 AND_000716 AND_000448 AND_000448 AND_001637 AND_001637 AND_000582 AND_000582 AND_000839 AND_000839 AND_002299 AND_002299 AND_002295 AND_002295 AND_000682 AND_000682 AND_002281 AND_002281 AND_001300 AND_001300 AND_001494 AND_001494 AND_003337 AND_003337 AND_004016 AND_004016 AND_004464 AND_004464 AND_004468 AND_004468 AND_004457 AND_004457 AND_004282 AND_004282 AND_005202 AND_005202 AND_003828 AND_003828 AND_004997 AND_004997 AND_004329 AND_004329 AND_005738 AND_005738 AND_004442 AND_004442 AND_004739 AND_004739 AND_006581 AND_006581 AND_006948 AND_006948 AND_005572 AND_005572 AND_006644 AND_006644 AND_005906 AND_005906 AND_000101 AND_000101 AND_000364 AND_000364 AND_000050 AND_000050 AND_001201 AND_001201 AND_004726 AND_004726 AND_010197 AND_010197 AND_010093 AND_010093 AND_005973 AND_005973 AND_005789 AND_005789 AND_007631 AND_007631 AND_006441 AND_006441 AND_007811 AND_007811 AND_007978 AND_007978 AND_007599 AND_007599 AND_007813 AND_007813 AND_007844 AND_007844 AND_007997 AND_007997 AND_009236 AND_009236 MCM7 MCM7 AND_009020 AND_009020 AND_008613 AND_008613 AND_009786 AND_009786 AND_009916 AND_009916
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AND_008458Origin recognition complex subunit 3. (698 aa)
AND_010209DNA polymerase delta small subunit. (456 aa)
AND_009607Fork head. (511 aa)
AND_010478Archipelago. (1642 aa)
AND_009634Uncharacterized protein. (1550 aa)
AND_009254DNA helicase; Belongs to the MCM family. (822 aa)
AND_009880DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (339 aa)
AND_010372Uncharacterized protein. (223 aa)
AND_010064Timeless protein. (1288 aa)
AND_000887Mini-chromosome maintenance complex-binding protein. (619 aa)
AND_001430RING-type domain-containing protein. (460 aa)
AND_000092Uncharacterized protein. (501 aa)
AND_001366Zinc finger protein. (121 aa)
AND_001632Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (461 aa)
AND_001484DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (236 aa)
AND_001581DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (575 aa)
AND_000382DNA ligase 4; Belongs to the ATP-dependent DNA ligase family. (954 aa)
AND_001838DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family. (1321 aa)
AND_001356Pita. (688 aa)
AND_000716DNA helicase; Belongs to the MCM family. (733 aa)
AND_000448CAF1-p150_C2 domain-containing protein. (663 aa)
AND_001637DNA polymerase epsilon subunit 3. (127 aa)
AND_000582DNA polymerase subunit gamma 1, mitochondrial. (1219 aa)
AND_000839Replication factor C subunit 3. (358 aa)
AND_002299DNA replication factor Cdt1. (702 aa)
AND_002295WD repeat and HMG-box DNA-binding protein 1. (1005 aa)
AND_000682Uncharacterized protein. (474 aa)
AND_002281Replication factor C subunit 2. (343 aa)
AND_001300Rif1_N domain-containing protein. (1970 aa)
AND_001494High mobility group protein DSP1. (494 aa)
AND_003337RNase H domain-containing protein. (1247 aa)
AND_004016DNA polymerase. (1593 aa)
AND_004464Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
AND_004468Rothmund-thomson syndrome DNA helicase recq4. (1671 aa)
AND_004457DNA helicase; Belongs to the MCM family. (815 aa)
AND_004282Single-stranded DNA-binding protein, mitochondrial. (134 aa)
AND_005202RING-type domain-containing protein. (721 aa)
AND_003828ATP-dependent DNA helicase hus2. (1444 aa)
AND_004997DNA helicase; Belongs to the MCM family. (888 aa)
AND_004329Psf3. (203 aa)
AND_005738Uncharacterized protein. (323 aa)
AND_004442Pom1. (692 aa)
AND_004739DNA primase; Belongs to the eukaryotic-type primase small subunit family. (428 aa)
AND_006581Downstream neighbor of Son. (593 aa)
AND_006948DNA polymerase. (1092 aa)
AND_005572Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (621 aa)
AND_006644Partner of sld5. (194 aa)
AND_005906Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance; Belongs to the MGME1 family. (353 aa)
AND_000101DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (234 aa)
AND_000364DNA helicase; Belongs to the MCM family. (873 aa)
AND_000050DNA replication helicase dna2. (1110 aa)
AND_001201ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (680 aa)
AND_004726DNA polymerase theta. (2046 aa)
AND_010197Tyrosine-protein kinase. (691 aa)
AND_010093Werner helicase interacting protein. (580 aa)
AND_005973Uncharacterized protein. (957 aa)
AND_005789Uncharacterized protein. (1097 aa)
AND_007631Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (471 aa)
AND_006441Replication factor c / DNA polymerase iii gamma-tau subunit. (327 aa)
AND_007811DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2234 aa)
AND_007978Uncharacterized protein. (565 aa)
AND_007599SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (717 aa)
AND_007813DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (524 aa)
AND_007844Origin recognition complex subunit 6. (266 aa)
AND_007997Timeout/timeless-2. (1181 aa)
AND_009236Uncharacterized protein. (1548 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (717 aa)
AND_009020WD_REPEATS_REGION domain-containing protein. (1744 aa)
AND_008613Replication factor C subunit 4. (360 aa)
AND_009786E2F_TDP domain-containing protein. (422 aa)
AND_009916DNA topoisomerase 2-binding protein 1. (653 aa)
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
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