STRINGSTRING
AND_000448 AND_000448 AND_000762 AND_000762 AND_001644 AND_001644 AND_001911 AND_001911 AND_000923 AND_000923 AND_001014 AND_001014 AND_002142 AND_002142 AND_002244 AND_002244 AND_002249 AND_002249 AND_002809 AND_002809 AND_002597 AND_002597 AND_003242 AND_003242 AND_002909 AND_002909 AND_001907 AND_001907 AND_002379 AND_002379 AND_002145 AND_002145 AND_002533 AND_002533 AND_004032 AND_004032 AND_004056 AND_004056 AND_003011 AND_003011 AND_004468 AND_004468 AND_002908 AND_002908 AND_004550 AND_004550 AND_004457 AND_004457 AND_004225 AND_004225 AND_005202 AND_005202 AND_005296 AND_005296 AND_004822 AND_004822 AND_005352 AND_005352 AND_005277 AND_005277 AND_003828 AND_003828 AND_004997 AND_004997 AND_005738 AND_005738 AND_004510 AND_004510 AND_005892 AND_005892 AND_005934 AND_005934 AND_004726 AND_004726 AND_004541 AND_004541 AND_006224 AND_006224 AND_005811 AND_005811 AND_004800 AND_004800 AND_006467 AND_006467 AND_005307 AND_005307 AND_006667 AND_006667 AND_005483 AND_005483 AND_005605 AND_005605 AND_005572 AND_005572 AND_007086 AND_007086 AND_005789 AND_005789 PIF1 PIF1 AND_010388 AND_010388 AND_009880 AND_009880 AND_009254 AND_009254 AND_010227 AND_010227 AND_009634 AND_009634 AND_009395 AND_009395 AND_010389 AND_010389 AND_010083 AND_010083 AND_010002 AND_010002 AND_009917 AND_009917 AND_009233 AND_009233 MCM7 MCM7 AND_009583 AND_009583 AND_008291 AND_008291 AND_007678 AND_007678 AND_009236 AND_009236 AND_009226 AND_009226 AND_007921 AND_007921 AND_008137 AND_008137 AND_006652 AND_006652 AND_006675 AND_006675 AND_007799 AND_007799 AND_007978 AND_007978 AND_007599 AND_007599 AND_008837 AND_008837 AND_008833 AND_008833 AND_008344 AND_008344 AND_008542 AND_008542 AND_000049 AND_000049 AND_000185 AND_000185 AND_000101 AND_000101 AND_000403 AND_000403 AND_000364 AND_000364 AND_000050 AND_000050 AND_001098 AND_001098 AND_000677 AND_000677 AND_001354 AND_001354 AND_001201 AND_001201 AND_001203 AND_001203 AND_001484 AND_001484 AND_001615 AND_001615 AND_000382 AND_000382 AND_001925 AND_001925 AND_000546 AND_000546 AND_000597 AND_000597 AND_001574 AND_001574 AND_000716 AND_000716
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AND_000448CAF1-p150_C2 domain-containing protein. (663 aa)
AND_000762DNA replication licensing factor MCM8; Belongs to the MCM family. (831 aa)
AND_001644Protein kinase domain-containing protein. (669 aa)
AND_001911Transcription-associated protein 1; Belongs to the PI3/PI4-kinase family. (1742 aa)
AND_000923DNA repair and recombination protein RAD54. (791 aa)
AND_001014TP6A_N domain-containing protein. (656 aa)
AND_002142XPG-like endonuclease. (747 aa)
AND_002244Ku domain-containing protein. (583 aa)
AND_002249DEAD box ATP-dependent RNA helicase. (728 aa)
AND_002809DNA cross-link repair 1A protein. (757 aa)
AND_002597FATC domain-containing protein. (1231 aa)
AND_003242SOSS complex subunit B. (240 aa)
AND_002909E1a binding protein P400. (1411 aa)
AND_001907Transcription-associated protein 1. (1862 aa)
AND_002379Ku P80 DNA helicase. (728 aa)
AND_002145Translationally controlled tumor protein; Belongs to the TCTP family. (171 aa)
AND_002533Crossover junction endonuclease MUS81. (462 aa)
AND_004032Transcription-associated protein 1. (544 aa)
AND_004056DNA polymerase eta. (876 aa)
AND_003011Enhancer of Polycomb. (2101 aa)
AND_004468Rothmund-thomson syndrome DNA helicase recq4. (1671 aa)
AND_002908E1a binding protein P400. (2899 aa)
AND_004550Structural maintenance of chromosomes 6 smc6. (1081 aa)
AND_004457DNA helicase; Belongs to the MCM family. (815 aa)
AND_004225Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (873 aa)
AND_005202RING-type domain-containing protein. (721 aa)
AND_005296MRG-binding protein. (222 aa)
AND_004822Spindle-b recombination protein spn-b. (273 aa)
AND_005352NUC194 domain-containing protein. (2413 aa)
AND_005277WD repeat-containing protein mio. (857 aa)
AND_003828ATP-dependent DNA helicase hus2. (1444 aa)
AND_004997DNA helicase; Belongs to the MCM family. (888 aa)
AND_005738Uncharacterized protein. (323 aa)
AND_004510Uncharacterized protein. (217 aa)
AND_005892Tyrosyl-dna phosphodiesterase. (625 aa)
AND_005934Structural maintenance of chromosomes 5 smc5. (1034 aa)
AND_004726DNA polymerase theta. (2046 aa)
AND_004541RAD51C protein. (330 aa)
AND_006224DNA repair protein RAD50. (1309 aa)
AND_005811DNA repair protein Rad21. (788 aa)
AND_004800Uncharacterized protein. (435 aa)
AND_006467DNA repair endonuclease xp-f / mei-9 / rad1. (1038 aa)
AND_005307Uncharacterized protein. (803 aa)
AND_006667Uncharacterized protein. (313 aa)
AND_005483FYVE-type domain-containing protein. (2290 aa)
AND_005605Actin; Belongs to the actin family. (422 aa)
AND_005572Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (621 aa)
AND_007086Quijote. (202 aa)
AND_005789Uncharacterized protein. (1097 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (680 aa)
AND_010388HIT domain-containing protein. (185 aa)
AND_009880DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (339 aa)
AND_009254DNA helicase; Belongs to the MCM family. (822 aa)
AND_010227Uncharacterized protein. (425 aa)
AND_009634Uncharacterized protein. (1550 aa)
AND_009395RING-type domain-containing protein. (707 aa)
AND_010389Uncharacterized protein. (105 aa)
AND_010083YEATS domain containing protein 4. (230 aa)
AND_010002DNA replication licensing factor MCM1; Belongs to the MCM family. (1039 aa)
AND_009917Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (458 aa)
AND_009233DNA polymerase zeta catalytic subunit. (2136 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (717 aa)
AND_009583Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family. (334 aa)
AND_008291DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1029 aa)
AND_007678Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (3165 aa)
AND_009236Uncharacterized protein. (1548 aa)
AND_009226Uncharacterized protein. (357 aa)
AND_007921BRCT domain-containing protein. (1412 aa)
AND_008137Serine/threonine-protein phosphatase. (273 aa)
AND_006652SUN domain-containing protein. (1140 aa)
AND_006675Putative 26s proteasome complex subunit dss1. (69 aa)
AND_007799Uncharacterized protein. (1207 aa)
AND_007978Uncharacterized protein. (565 aa)
AND_007599SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (717 aa)
AND_008837FHA domain-containing protein. (720 aa)
AND_008833Poly [ADP-ribose] polymerase. (1002 aa)
AND_008344Cyclin g; Belongs to the cyclin family. (540 aa)
AND_008542Uncharacterized protein. (879 aa)
AND_000049Uncharacterized protein. (1355 aa)
AND_000185Inhibitor of growth protein. (1087 aa)
AND_000101DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (234 aa)
AND_000403Checkpoint protein; Belongs to the HUS1 family. (294 aa)
AND_000364DNA helicase; Belongs to the MCM family. (873 aa)
AND_000050DNA replication helicase dna2. (1110 aa)
AND_001098Uncharacterized protein. (218 aa)
AND_000677Nipped-B protein. (2224 aa)
AND_001354Uncharacterized protein. (235 aa)
AND_001201ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (680 aa)
AND_001203DUF1767 domain-containing protein. (659 aa)
AND_001484DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (236 aa)
AND_001615Uncharacterized protein. (621 aa)
AND_000382DNA ligase 4; Belongs to the ATP-dependent DNA ligase family. (954 aa)
AND_001925WD repeat-containing protein 48. (725 aa)
AND_000546Uncharacterized protein. (116 aa)
AND_000597Uncharacterized protein. (1535 aa)
AND_001574DNA repair and recombination protein RAD54. (883 aa)
AND_000716DNA helicase; Belongs to the MCM family. (733 aa)
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
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