STRINGSTRING
AND_000737 AND_000737 AND_009864 AND_009864 AND_009312 AND_009312 AND_008378 AND_008378 AND_008908 AND_008908 AND_010256 AND_010256 AND_010332 AND_010332 AND_007801 AND_007801 AND_008285 AND_008285 AND_008563 AND_008563 AND_008377 AND_008377 AND_007452 AND_007452 AND_007354 AND_007354 AND_007047 AND_007047 AND_006284 AND_006284 AND_007510 AND_007510 AND_007405 AND_007405 AND_007353 AND_007353 AND_006988 AND_006988 AND_005487 AND_005487 AND_005811 AND_005811 AND_005685 AND_005685 AND_003675 AND_003675 AND_004636 AND_004636 AND_003677 AND_003677 AND_004944 AND_004944 AND_009858 AND_009858 AND_004651 AND_004651 AND_002974 AND_002974 AND_003679 AND_003679 AND_004012 AND_004012 AND_003912 AND_003912 AND_003678 AND_003678 AND_003158 AND_003158 AND_002310 AND_002310 AND_001769 AND_001769 AND_000659 AND_000659 AND_000337 AND_000337 AND_001119 AND_001119
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AND_000737Chromo domain-containing protein. (487 aa)
AND_009864Structural maintenance of chromosomes protein 1A. (590 aa)
AND_009312Tyrosine-protein phosphatase non-receptor type 23. (1778 aa)
AND_008378Ubiquitin-activating enzyme E1; Belongs to the ubiquitin-activating E1 family. (1073 aa)
AND_008908Draper. (1158 aa)
AND_010256Inhibitor of kappab kinase epsilon. (747 aa)
AND_010332Uncharacterized protein. (6844 aa)
AND_007801Skd/vacuolar sorting; Belongs to the AAA ATPase family. (433 aa)
AND_008285Uncharacterized protein. (2562 aa)
AND_008563Retinoid x receptor (Rxr). (561 aa)
AND_008377Nuclear receptor domain-containing protein. (466 aa)
AND_007452Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. (126 aa)
AND_007354WD_REPEATS_REGION domain-containing protein. (597 aa)
AND_007047Uncharacterized protein. (840 aa)
AND_006284IGF-II mRNA-binding protein. (746 aa)
AND_007510Ubiquitin carboxyl-terminal hydrolase. (955 aa)
AND_007405Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (759 aa)
AND_007353Immune response deficient 1. (903 aa)
AND_006988Nuclear receptor subfamily 2 group E member 3. (749 aa)
AND_005487Ced-6. (514 aa)
AND_005811DNA repair protein Rad21. (788 aa)
AND_005685Tumor susceptibility 101 protein. (411 aa)
AND_003675Calpain; Belongs to the peptidase C2 family. (1596 aa)
AND_004636Caspase short class; Belongs to the peptidase C14A family. (300 aa)
AND_003677Calpain; Belongs to the peptidase C2 family. (861 aa)
AND_004944Fragile X mental retardation syndrome-related protein 1. (808 aa)
AND_009858Structural maintenance of chromosomes smc1. (654 aa)
AND_004651Beclin-1. (442 aa)
AND_002974Calpain-c; Belongs to the peptidase C2 family. (681 aa)
AND_003679Calpain B; Belongs to the peptidase C2 family. (777 aa)
AND_004012Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (210 aa)
AND_003912BMERB domain-containing protein. (314 aa)
AND_003678Uncharacterized protein. (248 aa)
AND_003158Nuclear receptor subfamily 5 group A member 3. (590 aa)
AND_002310Charged multivesicular body protein 4b. (242 aa)
AND_001769Signal transducing adapter molecule (Stam). (762 aa)
AND_000659Ubiquitin-conjugating enzyme E2 D/E; Belongs to the ubiquitin-conjugating enzyme family. (184 aa)
AND_000337Skd/vacuolar sorting; Belongs to the AAA ATPase family. (442 aa)
AND_001119Uncharacterized protein. (1126 aa)
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
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