(23 nodes) Male genitalia morphogenesis network (Anopheles darlingi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_009108	Putative gtpase rab11/ypt3 small g protein. (214 aa)
	AND_009085	Mitogen-activated protein kinase. (453 aa)
	AND_007273	PDGF-and VEGF-receptor. (411 aa)
	AND_000752	Protein kinase domain-containing protein. (548 aa)
	AND_001503	Uncharacterized protein. (802 aa)
	AND_002111	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1507 aa)
	AND_003659	Notch. (2296 aa)
	AND_003837	Uncharacterized protein. (650 aa)
	AND_003822	Mixed lineage kinase. (1222 aa)
	AND_004013	Neural cell adhesion molecule. (1043 aa)
	AND_003616	Integrin beta subunit. (226 aa)
	AND_002605	Myosin-IB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1036 aa)
	AND_004656	Uncharacterized protein. (768 aa)
	AND_004291	Uncharacterized protein. (809 aa)
	AND_003615	Integrin beta; Belongs to the integrin beta chain family. (590 aa)
	AND_004292	Pdgf/vegf receptor. (528 aa)
	AND_005874	Uncharacterized protein. (468 aa)
	AND_004627	Uncharacterized protein. (814 aa)
	AND_005317	Vacuolar protein sorting-associated protein 25. (174 aa)
	AND_007047	Uncharacterized protein. (840 aa)
	AND_008463	Myosin i; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1025 aa)
	AND_009089	Mitogen-activated protein kinase. (390 aa)
	AND_009987	Dual specificity mitogen-activated protein kinase kinase hemipterous MAPKK. (1139 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000752	AND_002111	W5JWN9	W5JPQ3	Protein kinase domain-containing protein.	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.667
AND_000752	AND_003615	W5JWN9	W5JJT5	Protein kinase domain-containing protein.	Integrin beta; Belongs to the integrin beta chain family.	0.557
AND_000752	AND_003616	W5JWN9	W5JMU4	Protein kinase domain-containing protein.	Integrin beta subunit.	0.557
AND_001503	AND_002111	W5JRE3	W5JPQ3	Uncharacterized protein.	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.638
AND_001503	AND_003615	W5JRE3	W5JJT5	Uncharacterized protein.	Integrin beta; Belongs to the integrin beta chain family.	0.557
AND_001503	AND_003616	W5JRE3	W5JMU4	Uncharacterized protein.	Integrin beta subunit.	0.557
AND_002111	AND_000752	W5JPQ3	W5JWN9	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Protein kinase domain-containing protein.	0.667
AND_002111	AND_001503	W5JPQ3	W5JRE3	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.638
AND_002111	AND_003615	W5JPQ3	W5JJT5	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Integrin beta; Belongs to the integrin beta chain family.	0.800
AND_002111	AND_003616	W5JPQ3	W5JMU4	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Integrin beta subunit.	0.800
AND_002111	AND_003659	W5JPQ3	W5JPA3	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Notch.	0.790
AND_002111	AND_003822	W5JPQ3	W5JNE2	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Mixed lineage kinase.	0.659
AND_002111	AND_003837	W5JPQ3	W5JNR0	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.659
AND_002111	AND_004013	W5JPQ3	W5JN99	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Neural cell adhesion molecule.	0.807
AND_002111	AND_004291	W5JPQ3	W5JL02	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.638
AND_002111	AND_004292	W5JPQ3	W5JHX8	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Pdgf/vegf receptor.	0.668
AND_002111	AND_004627	W5JPQ3	W5JH15	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.638
AND_002111	AND_004656	W5JPQ3	W5JL34	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.638
AND_002111	AND_005874	W5JPQ3	W5JHR2	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.790
AND_002111	AND_007273	W5JPQ3	W5JCM2	PTK7 protein tyrosine kinase 7; Belongs to the protein kinase superfamily. Tyr protein kinase family.	PDGF-and VEGF-receptor.	0.638