51 items (Anopheles darlingi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_005435	SNARE Vti1a protein. (216 aa)
	AND_007416	Vesicle docking protein P115. (896 aa)
	AND_007047	Uncharacterized protein. (840 aa)
	AND_007169	Synaptobrevin. (112 aa)
	AND_007339	Uncharacterized protein. (235 aa)
	AND_007964	Golgi SNAP receptor complex member 1; Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor. (234 aa)
	AND_008814	Syntaxin 17. (319 aa)
	AND_009044	Syntaxin-18. (342 aa)
	AND_008540	RING-type domain-containing protein. (1274 aa)
	AND_009251	Putative ras-related protein rab-8a. (208 aa)
	AND_008298	Syntaxin; Belongs to the syntaxin family. (289 aa)
	AND_010109	Tubby; Belongs to the TUB family. (1773 aa)
	AND_009723	BTB domain-containing protein. (253 aa)
	AND_009108	Putative gtpase rab11/ypt3 small g protein. (214 aa)
	AND_009267	Vps16B. (452 aa)
	AND_009706	Sorting nexin; Involved in several stages of intracellular trafficking. (434 aa)
	AND_009863	Vacuolar protein sorting-associated; Belongs to the STXBP/unc-18/SEC1 family. (574 aa)
	AND_010049	RT14 protein. (122 aa)
	AND_000996	Syntaxin. (243 aa)
	AND_001062	CNH domain-containing protein. (904 aa)
	AND_000773	Protostome-specific GEF. (201 aa)
	AND_000067	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (836 aa)
	AND_001733	Membrin. (197 aa)
	AND_002140	Vacuolar membrane protein pep11. (1124 aa)
	AND_000771	C2 domain-containing protein. (296 aa)
	AND_002131	Uncharacterized protein. (141 aa)
	AND_002839	Light protein; Belongs to the FBPase class 1 family. (1248 aa)
	AND_001418	Leucine-rich transmembrane protein. (561 aa)
	AND_001755	Syntaxin-5; Belongs to the syntaxin family. (427 aa)
	AND_001929	V-SNARE coiled-coil homology domain-containing protein. (129 aa)
	AND_001806	t-SNARE coiled-coil homology domain-containing protein. (331 aa)
	AND_003766	NSFL1 cofactor p47. (397 aa)
	AND_003618	Uncharacterized protein; Belongs to the synaptobrevin family. (226 aa)
	AND_003260	Uncharacterized protein; Belongs to the synaptobrevin family. (200 aa)
	AND_003927	t-SNARE coiled-coil homology domain-containing protein. (119 aa)
	AND_002582	Transport protein SEC22; Belongs to the synaptobrevin family. (211 aa)
	AND_004177	Vacuolar protein sorting 18 (Deep orange protein). (982 aa)
	AND_004049	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (198 aa)
	AND_003043	ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	AND_003498	SNAPIN protein homolog; Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in pigment granule biogenesis. (134 aa)
	AND_003342	Uncharacterized protein. (361 aa)
	AND_003435	Ras-related protein Rab-7. (206 aa)
	AND_003986	Syntaxin-8. (231 aa)
	AND_005023	Use1. (237 aa)
	AND_005642	Syntaxin 1A; Belongs to the syntaxin family. (409 aa)
	AND_004377	t-SNARE coiled-coil homology domain-containing protein. (396 aa)
	AND_005812	Putative gtpase rab1/ypt1 small g protein. (215 aa)
	AND_005957	Soluble nsf attachment protein (Snap). (293 aa)
	AND_004640	YIPF5. (267 aa)
	AND_005988	Spermatogenesis associated factor; Belongs to the AAA ATPase family. (806 aa)
	AND_005699	Atlastin. (542 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000067	AND_000996	W5JV97	W5JVV0	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Syntaxin.	0.857
AND_000067	AND_001062	W5JV97	W5JVQ0	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	CNH domain-containing protein.	0.999
AND_000067	AND_001929	W5JV97	W5JQA4	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	V-SNARE coiled-coil homology domain-containing protein.	0.823
AND_000067	AND_002140	W5JV97	W5JTK5	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Vacuolar membrane protein pep11.	0.998
AND_000067	AND_002839	W5JV97	W5JRN4	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Light protein; Belongs to the FBPase class 1 family.	0.998
AND_000067	AND_003043	W5JV97	W5JLE3	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	ADP-ribosylation factor; Belongs to the small GTPase superfamily. Arf family.	0.472
AND_000067	AND_003260	W5JV97	W5JNV0	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.972
AND_000067	AND_003435	W5JV97	W5JKB4	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Ras-related protein Rab-7.	0.696
AND_000067	AND_003618	W5JV97	W5JP14	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein; Belongs to the synaptobrevin family.	0.943
AND_000067	AND_003986	W5JV97	W5JJE9	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Syntaxin-8.	0.876
AND_000067	AND_004177	W5JV97	W5JMU1	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Vacuolar protein sorting 18 (Deep orange protein).	0.999
AND_000067	AND_004377	W5JV97	W5JIH4	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	t-SNARE coiled-coil homology domain-containing protein.	0.404
AND_000067	AND_005435	W5JV97	W5JFP3	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	SNARE Vti1a protein.	0.980
AND_000067	AND_005812	W5JV97	W5JI85	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Putative gtpase rab1/ypt1 small g protein.	0.449
AND_000067	AND_005957	W5JV97	W5JHT4	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Soluble nsf attachment protein (Snap).	0.469
AND_000067	AND_007047	W5JV97	W5JD59	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Uncharacterized protein.	0.706
AND_000067	AND_007169	W5JV97	W5JCV4	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Synaptobrevin.	0.823
AND_000067	AND_008298	W5JV97	W5J6K3	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Syntaxin; Belongs to the syntaxin family.	0.951
AND_000067	AND_008540	W5JV97	W5J8Y2	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	RING-type domain-containing protein.	0.996
AND_000067	AND_008814	W5JV97	W5J9Z8	Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family.	Syntaxin 17.	0.959