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AND_004029 AND_004029 AND_003509 AND_003509 Sgf11 Sgf11 AND_001138 AND_001138 AND_000362 AND_000362 AND_001148 AND_001148 e(y)2 e(y)2 AND_000185 AND_000185 AND_008707 AND_008707 AND_009009 AND_009009 AND_007690 AND_007690 AND_007512 AND_007512 AND_006902 AND_006902
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AND_004029Inhibitor of growth protein. (591 aa)
AND_003509E3 ubiquitin protein ligase. (1073 aa)
Sgf11SAGA-associated factor 11 homolog; Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates histone H2B. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. (180 aa)
AND_001138RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (482 aa)
AND_000362Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1180 aa)
AND_001148RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. (456 aa)
e(y)2Enhancer of yellow 2 transcription factor; Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates histones. The SAGA complex is recruited to specific gene promoters by activators, where it is required for transcription. The TREX-2 complex [...] (93 aa)
AND_000185Inhibitor of growth protein. (1087 aa)
AND_008707Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa)
AND_009009Inhibitor of growth protein. (286 aa)
AND_007690Protein HIRA; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (937 aa)
AND_007512Histone-lysine N-methyltransferase, H3 lysine-79 specific. (2406 aa)
AND_006902Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (491 aa)
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
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