(52 nodes) Apoptosis network (Anopheles darlingi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_010252	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (745 aa)
	AND_000222	Uncharacterized protein. (1395 aa)
	AND_000607	Protein farnesyltransferase alpha subunit. (340 aa)
	AND_000221	Kakapo. (7372 aa)
	AND_000436	Lamin; Belongs to the intermediate filament family. (554 aa)
	AND_002192	Baculoviral IAP repeat-containing protein 3. (508 aa)
	AND_001704	Uncharacterized protein. (1439 aa)
	AND_002368	Gelsolin. (388 aa)
	AND_001126	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (990 aa)
	AND_000956	Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1325 aa)
	AND_001492	Buffy. (285 aa)
	AND_002364	Gelsolin. (737 aa)
	AND_002432	Apoptosis 1 inhibitor. (447 aa)
	AND_001493	Bcl-2 associated protein. (288 aa)
	AND_001494	High mobility group protein DSP1. (494 aa)
	AND_003119	Defective proventriculus. (917 aa)
	AND_003355	Importin subunit alpha; Belongs to the importin alpha family. (521 aa)
	AND_002041	Villin. (908 aa)
	AND_002207	Bcl-2 associated protein. (298 aa)
	AND_002425	RING-type domain-containing protein. (337 aa)
	AND_003603	Uncharacterized protein; Belongs to the peptidase C14A family. (355 aa)
	AND_004267	Uncharacterized protein. (1221 aa)
	AND_002695	Frazzled protein. (1491 aa)
	AND_002846	Probable methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (239 aa)
	AND_004024	Tight junction protein; Belongs to the MAGUK family. (2363 aa)
	AND_004658	Uncharacterized protein. (1375 aa)
	AND_004116	Uncharacterized protein. (631 aa)
	AND_004675	Histone H1. (239 aa)
	AND_004945	Armadillo. (748 aa)
	AND_004954	Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (358 aa)
	AND_003452	Septin; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (363 aa)
	AND_003781	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	AND_004636	Caspase short class; Belongs to the peptidase C14A family. (300 aa)
	AND_003947	Caspase long class, Dredd; Belongs to the peptidase C14A family. (507 aa)
	AND_004958	Uncharacterized protein. (127 aa)
	AND_003945	DUF4203 domain-containing protein. (366 aa)
	AND_005913	Bcr-associated protein, bap. (231 aa)
	AND_004285	Importin subunit beta. (904 aa)
	AND_004676	Histone H1. (232 aa)
	AND_006040	Endophilin b. (362 aa)
	AND_006242	Caspase-activated nuclease. (428 aa)
	AND_006624	Plakophilin-4. (1015 aa)
	AND_006875	Serine/threonine protein kinase. (886 aa)
	AND_006521	Histone H1. (236 aa)
	AND_008113	Microtubule-associated protein. (842 aa)
	AND_007593	RRM domain-containing protein. (908 aa)
	AND_006593	Histone H1/5. (229 aa)
	AND_008695	Importin subunit alpha; Belongs to the importin alpha family. (519 aa)
	AND_007916	Spectrin. (2417 aa)
	AND_009977	Cytochrome c proximal; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	AND_010197	Tyrosine-protein kinase. (691 aa)
	AND_010654	CIDE-N domain-containing protein. (706 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000221	AND_000222	W5JUD2	W5JWF7	Kakapo.	Uncharacterized protein.	0.922
AND_000221	AND_000436	W5JUD2	W5JU89	Kakapo.	Lamin; Belongs to the intermediate filament family.	0.772
AND_000221	AND_000956	W5JUD2	W5JS74	Kakapo.	Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.499
AND_000221	AND_003603	W5JUD2	W5JMV4	Kakapo.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.630
AND_000221	AND_003945	W5JUD2	W5JIW3	Kakapo.	DUF4203 domain-containing protein.	0.589
AND_000221	AND_003947	W5JUD2	W5JJK4	Kakapo.	Caspase long class, Dredd; Belongs to the peptidase C14A family.	0.589
AND_000221	AND_004636	W5JUD2	W5JK07	Kakapo.	Caspase short class; Belongs to the peptidase C14A family.	0.630
AND_000221	AND_004945	W5JUD2	W5JKN4	Kakapo.	Armadillo.	0.751
AND_000221	AND_004958	W5JUD2	W5JJ62	Kakapo.	Uncharacterized protein.	0.751
AND_000221	AND_006624	W5JUD2	W5JFN7	Kakapo.	Plakophilin-4.	0.634
AND_000221	AND_007916	W5JUD2	W5J914	Kakapo.	Spectrin.	0.732
AND_000221	AND_010197	W5JUD2	W5J1S8	Kakapo.	Tyrosine-protein kinase.	0.487
AND_000222	AND_000221	W5JWF7	W5JUD2	Uncharacterized protein.	Kakapo.	0.922
AND_000222	AND_000436	W5JWF7	W5JU89	Uncharacterized protein.	Lamin; Belongs to the intermediate filament family.	0.638
AND_000222	AND_000956	W5JWF7	W5JS74	Uncharacterized protein.	Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.499
AND_000222	AND_003603	W5JWF7	W5JMV4	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.630
AND_000222	AND_003945	W5JWF7	W5JIW3	Uncharacterized protein.	DUF4203 domain-containing protein.	0.577
AND_000222	AND_003947	W5JWF7	W5JJK4	Uncharacterized protein.	Caspase long class, Dredd; Belongs to the peptidase C14A family.	0.577
AND_000222	AND_004636	W5JWF7	W5JK07	Uncharacterized protein.	Caspase short class; Belongs to the peptidase C14A family.	0.630
AND_000222	AND_004945	W5JWF7	W5JKN4	Uncharacterized protein.	Armadillo.	0.751