(26 nodes) G-protein mediated events network (Anopheles darlingi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_001914	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1225 aa)
	AND_002688	Putative camp-dependent protein kinase catalytic subunit; Belongs to the protein kinase superfamily. (353 aa)
	AND_004212	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (675 aa)
	AND_003013	Camp-dependent protein kinase type i-beta regulatory subunit. (321 aa)
	AND_004759	Low molecular weight protein-tyrosine-phosphatase. (162 aa)
	AND_003465	Camp-dependent protein kinase catalytic subunit; Belongs to the protein kinase superfamily. (353 aa)
	AND_003781	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
	AND_005429	Uncharacterized protein. (126 aa)
	AND_004215	Adenylate cyclase. (608 aa)
	AND_005690	Rugose. (3560 aa)
	AND_005942	Phospholipase c beta. (150 aa)
	AND_005410	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1190 aa)
	AND_005474	Adenylate cyclase type; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (2346 aa)
	AND_007341	Adenylate cyclase type ix; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1729 aa)
	AND_005940	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1072 aa)
	AND_007580	Phosphoinositide phospholipase C. (1682 aa)
	AND_008400	Protein kinase C. (61 aa)
	AND_009311	Beta-adrenergic receptor kinase. (772 aa)
	AND_009771	Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1272 aa)
	AND_009898	Adenylate cyclase type vi. (1278 aa)
	AND_009550	Calcium/calmodulin-dependent protein kinase kinase. (809 aa)
	AND_008876	GTP-binding protein alpha subunit, gna. (299 aa)
	AND_007739	Calcium/calmodulin-dependent protein kinase type 1. (628 aa)
	AND_001351	GTP-binding protein alpha subunit, gna. (384 aa)
	AND_002326	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (617 aa)
	AND_002352	Phosphodiesterase. (485 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_001351	AND_001914	W5JV65	W5JPE3	GTP-binding protein alpha subunit, gna.	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.735
AND_001351	AND_003013	W5JV65	W5JLH0	GTP-binding protein alpha subunit, gna.	Camp-dependent protein kinase type i-beta regulatory subunit.	0.406
AND_001351	AND_004212	W5JV65	W5JMB9	GTP-binding protein alpha subunit, gna.	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.735
AND_001351	AND_004215	W5JV65	W5JIU5	GTP-binding protein alpha subunit, gna.	Adenylate cyclase.	0.735
AND_001351	AND_004759	W5JV65	W5JL91	GTP-binding protein alpha subunit, gna.	Low molecular weight protein-tyrosine-phosphatase.	0.735
AND_001351	AND_005410	W5JV65	W5JFN6	GTP-binding protein alpha subunit, gna.	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.735
AND_001351	AND_005429	W5JV65	W5JJ20	GTP-binding protein alpha subunit, gna.	Uncharacterized protein.	0.735
AND_001351	AND_005474	W5JV65	W5JFH5	GTP-binding protein alpha subunit, gna.	Adenylate cyclase type; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.735
AND_001351	AND_007341	W5JV65	W5JDP0	GTP-binding protein alpha subunit, gna.	Adenylate cyclase type ix; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.972
AND_001351	AND_009771	W5JV65	W5J5G6	GTP-binding protein alpha subunit, gna.	Adenylate cyclase 2; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.735
AND_001351	AND_009898	W5JV65	W5J6K4	GTP-binding protein alpha subunit, gna.	Adenylate cyclase type vi.	0.735
AND_001914	AND_001351	W5JPE3	W5JV65	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	GTP-binding protein alpha subunit, gna.	0.735
AND_001914	AND_002326	W5JPE3	W5JP71	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.428
AND_001914	AND_002352	W5JPE3	W5JP19	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Phosphodiesterase.	0.907
AND_001914	AND_002688	W5JPE3	W5JN41	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Putative camp-dependent protein kinase catalytic subunit; Belongs to the protein kinase superfamily.	0.833
AND_001914	AND_003013	W5JPE3	W5JLH0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Camp-dependent protein kinase type i-beta regulatory subunit.	0.482
AND_001914	AND_003465	W5JPE3	W5JKX0	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Camp-dependent protein kinase catalytic subunit; Belongs to the protein kinase superfamily.	0.833
AND_001914	AND_004212	W5JPE3	W5JMB9	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.869
AND_001914	AND_004215	W5JPE3	W5JIU5	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase.	0.596
AND_001914	AND_005410	W5JPE3	W5JFN6	Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.485