STRINGSTRING
AND_001035 AND_001035 AND_002473 AND_002473 AND_000616 AND_000616 AND_001862 AND_001862 AND_000842 AND_000842 AND_000790 AND_000790 AND_000297 AND_000297 AND_000891 AND_000891 AND_000141 AND_000141 AND_001338 AND_001338 AND_001467 AND_001467 AND_001836 AND_001836 AND_002894 AND_002894 AND_005284 AND_005284 AND_005224 AND_005224 AND_004906 AND_004906 AND_003778 AND_003778 AND_003985 AND_003985 AND_005115 AND_005115 AND_005904 AND_005904 AND_006092 AND_006092 AND_006066 AND_006066 AND_004615 AND_004615 AND_006129 AND_006129 AND_005336 AND_005336 AND_006582 AND_006582 AND_005046 AND_005046 AND_005983 AND_005983 AND_007642 AND_007642 AND_006086 AND_006086 AND_007401 AND_007401 AND_007920 AND_007920 AND_007610 AND_007610 AND_007630 AND_007630 AND_009495 AND_009495 AND_008565 AND_008565 AND_009743 AND_009743 AND_008215 AND_008215 AND_010298 AND_010298 AND_009299 AND_009299 AND_010187 AND_010187 AND_010608 AND_010608 AND_010315 AND_010315 AND_003610 AND_003610 AND_003453 AND_003453 AND_004116 AND_004116
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AND_001035Kokopelli. (112 aa)
AND_002473Uncharacterized protein. (2482 aa)
AND_000616DNA-directed RNA polymerases I, II, and III subunit RPABC5. (67 aa)
AND_001862HDAg domain-containing protein. (1201 aa)
AND_000842DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1880 aa)
AND_000790TFIIS N-terminal domain-containing protein. (814 aa)
AND_000297Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (583 aa)
AND_000891Elongation factor SIII p15 subunit; Belongs to the SKP1 family. (115 aa)
AND_000141Rad25/xp-b DNA repair helicase. (817 aa)
AND_001338General transcription factor IIF subunit 2; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. This subunit shows ATP-dependent DNA-helicase activity. (271 aa)
AND_001467RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (844 aa)
AND_001836DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (127 aa)
AND_002894Tfb5. (73 aa)
AND_005284Cell division protein kinase 9; Belongs to the protein kinase superfamily. (398 aa)
AND_005224Transcription elongation factor s-ii. (332 aa)
AND_004906Negative elongation factor D. (604 aa)
AND_003778DNA-directed RNA polymerase II subunit. (273 aa)
AND_003985Negative elongation factor E. (298 aa)
AND_005115FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (730 aa)
AND_005904General transcription factor IIH subunit. (418 aa)
AND_006092Negative elongation factor B. (588 aa)
AND_006066Putative dna-directed rna polymerase ii. (210 aa)
AND_004615General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (497 aa)
AND_006129TFIIH basal transcription factor complex subunit 1. (638 aa)
AND_005336Transcription elongation factor SPT4; Component of the DRB sensitivity-inducing factor complex (DSIF complex), which regulates transcription elongation by RNA polymerase II; Belongs to the SPT4 family. (116 aa)
AND_006582DNA-directed RNA polymerase subunit rpb6. (131 aa)
AND_005046DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
AND_005983TFIIH basal transcription factor complex p34 subunit. (288 aa)
AND_007642Negative elongation factor E. (314 aa)
AND_006086CDK-activating kinase assembly factor MAT1. (316 aa)
AND_007401DNA-directed RNA polymerase II 19 kDa polypeptide. (173 aa)
AND_007920CYCLIN domain-containing protein; Belongs to the cyclin family. (1454 aa)
AND_007610Cyclin h; Belongs to the cyclin family. (333 aa)
AND_007630DUF2236 domain-containing protein. (356 aa)
AND_009495Cyclin k; Belongs to the cyclin family. (384 aa)
AND_008565DNA repair helicase rad3/xp-d. (760 aa)
AND_009743Elongin b. (116 aa)
AND_008215DNA-directed RNA polymerase II subunit J. (117 aa)
AND_010298DUF2236 domain-containing protein. (447 aa)
AND_009299Putative dna-directed rna polymerase ii 16 kDa polypeptide. (139 aa)
AND_010187Transcription elongation factor SPT5. (1089 aa)
AND_010608FACT complex subunit spt16. (1081 aa)
AND_010315Cyclin; Belongs to the cyclin family. (257 aa)
AND_003610Protein kinase domain-containing protein. (1435 aa)
AND_003453Cak1; Belongs to the protein kinase superfamily. (343 aa)
AND_004116Uncharacterized protein. (631 aa)
Your Current Organism:
Anopheles darlingi
NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.