36 items (Anopheles darlingi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_000681	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (656 aa)
	AND_000781	Uncharacterized protein. (209 aa)
	AND_003926	Cyclin D2; Belongs to the cyclin family. (390 aa)
	AND_005496	S-phase kinase-associated protein 2. (386 aa)
	AND_003988	KxDL domain-containing protein. (247 aa)
	AND_003809	Fibronectin type-III domain-containing protein 3a. (1446 aa)
	AND_004480	Phosphatase 2. (459 aa)
	AND_003453	Cak1; Belongs to the protein kinase superfamily. (343 aa)
	AND_003338	Uncharacterized protein. (243 aa)
	AND_002691	Phosphatase 4. (1372 aa)
	AND_004306	Cell division protein kinase 4; Belongs to the protein kinase superfamily. (304 aa)
	AND_001827	Serine/threonine-protein phosphatase. (309 aa)
	AND_001537	Uncharacterized protein. (122 aa)
	AND_001535	Protein phosphatase 2 (Formerly 2A), regulatory subunit B. (1011 aa)
	AND_000733	Jak kinase hopscotch. (337 aa)
	AND_001536	Uncharacterized protein. (725 aa)
	AND_001304	Transcription factor dp. (512 aa)
	AND_004858	E2F_TDP domain-containing protein. (807 aa)
	AND_001696	Cdk1; Belongs to the protein kinase superfamily. (339 aa)
	AND_006215	Ubiquitin/60S ribosomal protein L40 fusion. (128 aa)
	AND_010372	Uncharacterized protein. (223 aa)
	AND_009125	Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (75 aa)
	AND_008874	Tyrosine-protein kinase. (739 aa)
	AND_009504	Skp1; Belongs to the SKP1 family. (162 aa)
	AND_008410	Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (445 aa)
	AND_009786	E2F_TDP domain-containing protein. (422 aa)
	AND_009479	Cullin; Belongs to the cullin family. (778 aa)
	AND_009204	Ubiquitin. (77 aa)
	AND_007610	Cyclin h; Belongs to the cyclin family. (333 aa)
	AND_007380	Tyrosine-protein kinase. (537 aa)
	AND_006536	Ubiquitin. (78 aa)
	AND_006086	CDK-activating kinase assembly factor MAT1. (316 aa)
	AND_007577	Serine/threonine protein phosphatase 2a regulatory subunit a. (962 aa)
	AND_005973	Uncharacterized protein. (957 aa)
	AND_006534	Ubiquitin-5E. (154 aa)
	AND_006351	Cyclin e; Belongs to the cyclin family. (564 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000681	AND_000733	W5JWD1	W5JTK4	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Jak kinase hopscotch.	0.452
AND_000681	AND_000781	W5JWD1	W5JWM6	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.573
AND_000681	AND_001696	W5JWD1	W5JUU0	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Cdk1; Belongs to the protein kinase superfamily.	0.742
AND_000681	AND_001827	W5JWD1	W5JPS4	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Serine/threonine-protein phosphatase.	0.610
AND_000681	AND_002691	W5JWD1	W5JMA8	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Phosphatase 4.	0.599
AND_000681	AND_003809	W5JWD1	W5JK13	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Fibronectin type-III domain-containing protein 3a.	0.501
AND_000681	AND_003926	W5JWD1	W5JIZ6	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Cyclin D2; Belongs to the cyclin family.	0.564
AND_000681	AND_004306	W5JWD1	W5JMI6	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Cell division protein kinase 4; Belongs to the protein kinase superfamily.	0.738
AND_000681	AND_006215	W5JWD1	B6DDR1	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Ubiquitin/60S ribosomal protein L40 fusion.	0.573
AND_000681	AND_006351	W5JWD1	W5JGE9	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Cyclin e; Belongs to the cyclin family.	0.593
AND_000681	AND_006534	W5JWD1	W5JEN8	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Ubiquitin-5E.	0.591
AND_000681	AND_006536	W5JWD1	W5JCI8	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Ubiquitin.	0.573
AND_000681	AND_007380	W5JWD1	W5JAG1	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Tyrosine-protein kinase.	0.616
AND_000681	AND_007577	W5JWD1	W5JD51	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Serine/threonine protein phosphatase 2a regulatory subunit a.	0.599
AND_000681	AND_009204	W5JWD1	W5J8K3	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Ubiquitin.	0.573
AND_000681	AND_009479	W5JWD1	W5J826	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Cullin; Belongs to the cullin family.	0.656
AND_000681	AND_009504	W5JWD1	W5J6B0	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Skp1; Belongs to the SKP1 family.	0.625
AND_000681	AND_010372	W5JWD1	W5J3Z9	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	Uncharacterized protein.	0.631
AND_000733	AND_000681	W5JTK4	W5JWD1	Jak kinase hopscotch.	Tyrosine protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.452
AND_000733	AND_000781	W5JTK4	W5JWM6	Jak kinase hopscotch.	Uncharacterized protein.	0.573